Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Standard

Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. / Mkupasi, Ernatus Martin; Sikasunge, Chummy Sikalizyo; Ngowi, Helena Aminiel; Johansen, Maria Vang.

I: P L o S Neglected Tropical Diseases (Online), Bind 7, Nr. 7, e2200, 2013.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Mkupasi, EM, Sikasunge, CS, Ngowi, HA & Johansen, MV 2013, 'Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs', P L o S Neglected Tropical Diseases (Online), bind 7, nr. 7, e2200. https://doi.org/10.1371/journal.pntd.0002200

APA

Mkupasi, E. M., Sikasunge, C. S., Ngowi, H. A., & Johansen, M. V. (2013). Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. P L o S Neglected Tropical Diseases (Online), 7(7), [e2200]. https://doi.org/10.1371/journal.pntd.0002200

Vancouver

Mkupasi EM, Sikasunge CS, Ngowi HA, Johansen MV. Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. P L o S Neglected Tropical Diseases (Online). 2013;7(7). e2200. https://doi.org/10.1371/journal.pntd.0002200

Author

Mkupasi, Ernatus Martin ; Sikasunge, Chummy Sikalizyo ; Ngowi, Helena Aminiel ; Johansen, Maria Vang. / Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs. I: P L o S Neglected Tropical Diseases (Online). 2013 ; Bind 7, Nr. 7.

Bibtex

@article{717793c36cd54a3d9edb909da52df7cf,
title = "Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs",
abstract = "Porcine cysticercosis, an infection caused by Taenia solium metacestodes, is continuously being reported in low-income countries of Latin America, Asia, and sub-Saharan Africa. The disease was declared eradicable by the International Task Force for Diseases Eradication (ITFDE) in 1993, and it is listed among the 17 WHO Neglected Tropical Diseases and Neglected Zoonoses that are potentially eradicable. In view of that, WHO has proposed a step-wise approach to its elimination, including chemotherapy of infected pigs. Different drugs have been tested on porcine cysticercosis with varying efficacies. These include flubendazole, fenbendazole, albendazole, albendazole sulphoxide, oxfendazole, praziquantel, and nitazoxanide. This review summarises available information on the efficacies and adverse effects shown by these drugs in pigs. Oxfendazole has shown to be effective for the control of porcine cysticercosis; however, it needs to be integrated with other control approaches. There is a need for standardised guidelines for evaluating the efficacy of anthelmintics against porcine cysticercosis, and more efficacy studies are needed since the conclusions so far are based on a limited number of studies using few infected pigs.",
author = "Mkupasi, {Ernatus Martin} and Sikasunge, {Chummy Sikalizyo} and Ngowi, {Helena Aminiel} and Johansen, {Maria Vang}",
year = "2013",
doi = "10.1371/journal.pntd.0002200",
language = "English",
volume = "7",
journal = "P L o S Neglected Tropical Diseases (Online)",
issn = "1935-2735",
publisher = "Public Library of Science",
number = "7",

}

RIS

TY - JOUR

T1 - Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs

AU - Mkupasi, Ernatus Martin

AU - Sikasunge, Chummy Sikalizyo

AU - Ngowi, Helena Aminiel

AU - Johansen, Maria Vang

PY - 2013

Y1 - 2013

N2 - Porcine cysticercosis, an infection caused by Taenia solium metacestodes, is continuously being reported in low-income countries of Latin America, Asia, and sub-Saharan Africa. The disease was declared eradicable by the International Task Force for Diseases Eradication (ITFDE) in 1993, and it is listed among the 17 WHO Neglected Tropical Diseases and Neglected Zoonoses that are potentially eradicable. In view of that, WHO has proposed a step-wise approach to its elimination, including chemotherapy of infected pigs. Different drugs have been tested on porcine cysticercosis with varying efficacies. These include flubendazole, fenbendazole, albendazole, albendazole sulphoxide, oxfendazole, praziquantel, and nitazoxanide. This review summarises available information on the efficacies and adverse effects shown by these drugs in pigs. Oxfendazole has shown to be effective for the control of porcine cysticercosis; however, it needs to be integrated with other control approaches. There is a need for standardised guidelines for evaluating the efficacy of anthelmintics against porcine cysticercosis, and more efficacy studies are needed since the conclusions so far are based on a limited number of studies using few infected pigs.

AB - Porcine cysticercosis, an infection caused by Taenia solium metacestodes, is continuously being reported in low-income countries of Latin America, Asia, and sub-Saharan Africa. The disease was declared eradicable by the International Task Force for Diseases Eradication (ITFDE) in 1993, and it is listed among the 17 WHO Neglected Tropical Diseases and Neglected Zoonoses that are potentially eradicable. In view of that, WHO has proposed a step-wise approach to its elimination, including chemotherapy of infected pigs. Different drugs have been tested on porcine cysticercosis with varying efficacies. These include flubendazole, fenbendazole, albendazole, albendazole sulphoxide, oxfendazole, praziquantel, and nitazoxanide. This review summarises available information on the efficacies and adverse effects shown by these drugs in pigs. Oxfendazole has shown to be effective for the control of porcine cysticercosis; however, it needs to be integrated with other control approaches. There is a need for standardised guidelines for evaluating the efficacy of anthelmintics against porcine cysticercosis, and more efficacy studies are needed since the conclusions so far are based on a limited number of studies using few infected pigs.

U2 - 10.1371/journal.pntd.0002200

DO - 10.1371/journal.pntd.0002200

M3 - Journal article

C2 - 23936558

VL - 7

JO - P L o S Neglected Tropical Diseases (Online)

JF - P L o S Neglected Tropical Diseases (Online)

SN - 1935-2735

IS - 7

M1 - e2200

ER -

ID: 49458918