Expression of nitric oxide synthases and effects of L-arginine and L-NMMA on nitric oxide production and fluid transport in collagenous colitis

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Luminal nitric oxide (NO) is greatly increased in the colon of patients with collagenous and ulcerative colitis. To define the source and consequence of enhanced NO production we have studied expression of NO synthase (NOS) isoforms and nitrotyrosine in mucosal biopsies from these patients. In addition, effects on colonic fluid transfer caused by manipulating the substrate of NOS were studied in patients with collagenous colitis.
OriginalsprogEngelsk
TidsskriftGut
Vol/bind49
Udgave nummer3
Sider (fra-til)387-94
Antal sider8
ISSN0017-5749
StatusUdgivet - 2001

ID: 35922714