Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region: A systematic review and meta-analysis

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Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region : A systematic review and meta-analysis. / Olsen, Abbey; Berg, Rebecca P. K. Dorph; Tagel, Maarja; Must, Kärt; Deksne, Gunita; Enemark, Heidi Larsen; Alban, Lis; Johansen, Maria Vang; Nielsen, Henrik Vedel; Sandberg, Marianne; Lundén, Anna; Stensvold, Christen Rune; Pires, Sara Monteiro; Jokelainen, Pikka.

I: Parasite Epidemiology and Control, Bind 5, e00100, 05.2019, s. 1-13.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Olsen, A, Berg, RPKD, Tagel, M, Must, K, Deksne, G, Enemark, HL, Alban, L, Johansen, MV, Nielsen, HV, Sandberg, M, Lundén, A, Stensvold, CR, Pires, SM & Jokelainen, P 2019, 'Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region: A systematic review and meta-analysis', Parasite Epidemiology and Control, bind 5, e00100, s. 1-13. https://doi.org/10.1016/j.parepi.2019.e00100

APA

Olsen, A., Berg, R. P. K. D., Tagel, M., Must, K., Deksne, G., Enemark, H. L., Alban, L., Johansen, M. V., Nielsen, H. V., Sandberg, M., Lundén, A., Stensvold, C. R., Pires, S. M., & Jokelainen, P. (2019). Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region: A systematic review and meta-analysis. Parasite Epidemiology and Control, 5, 1-13. [e00100]. https://doi.org/10.1016/j.parepi.2019.e00100

Vancouver

Olsen A, Berg RPKD, Tagel M, Must K, Deksne G, Enemark HL o.a. Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region: A systematic review and meta-analysis. Parasite Epidemiology and Control. 2019 maj;5:1-13. e00100. https://doi.org/10.1016/j.parepi.2019.e00100

Author

Olsen, Abbey ; Berg, Rebecca P. K. Dorph ; Tagel, Maarja ; Must, Kärt ; Deksne, Gunita ; Enemark, Heidi Larsen ; Alban, Lis ; Johansen, Maria Vang ; Nielsen, Henrik Vedel ; Sandberg, Marianne ; Lundén, Anna ; Stensvold, Christen Rune ; Pires, Sara Monteiro ; Jokelainen, Pikka. / Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region : A systematic review and meta-analysis. I: Parasite Epidemiology and Control. 2019 ; Bind 5. s. 1-13.

Bibtex

@article{a759f832a5a04dfeaff5e21d0877ef57,
title = "Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region: A systematic review and meta-analysis",
abstract = "Background Toxoplasma gondii is an important foodborne zoonotic parasite. Meat of infected animals is presumed to constitute a major source of human infection and may be a driver of geographical variation in the prevalence of anti-T. gondii antibodies in humans, which is substantial in the Nordic-Baltic region in northern Europe. However, data on seroprevalence of T. gondii in different animal species used for human consumption are scattered. Methods We conducted a systematic review of seroprevalence studies and meta-analysis to estimate the seroprevalence of T. gondii in five animal species that are raised or hunted for human consumption in the Nordic-Baltic region: domestic pigs (Sus scrofa domesticus), sheep (Ovis aries), cattle (Bos taurus), wild boars (Sus scrofa), and moose (Alces alces). We searched for studies that were conducted between January 1990 and June 2018, and reported in articles, theses, conference abstracts and proceedings, and manuscripts. Subgroup analyses were performed to identify variables influencing the seroprevalence. Findings From a total of 271 studies identified in the systematic review, 32 were included in the meta-analysis. These comprised of 13 studies on domestic pigs, six on sheep, three on cattle, six on wild boars, and four on moose. The estimated pooled seroprevalence of T. gondii was 6% in domestic pigs (CI95%: 3–10%), 23% in sheep (CI95%: 12–36%), 7% in cattle (CI95%: 1–21%), 33% in wild boars (CI95%: 26–41%), and 16% in moose (CI95%: 10–23%). High heterogeneity was observed in the seroprevalence data within each species. In all host species except wild boars, the pooled seroprevalence estimates were significantly higher in animals >1 year of age than in younger animals. Not all studies provided information on animal age, sensitivity and specificity of the serological method employed, and the cut-off values used for defining an animal seropositive. Conclusions A substantial proportion of animals raised or hunted for human consumption in the region had tested positive for T. gondii. This indicates widespread exposure to T. gondii among animals raised or hunted for human consumption in the region. Large variations were observed in the seroprevalence estimates between the studies in the region; however, studies were too few to identify spatial patterns at country-level.",
author = "Abbey Olsen and Berg, {Rebecca P. K. Dorph} and Maarja Tagel and K{\"a}rt Must and Gunita Deksne and Enemark, {Heidi Larsen} and Lis Alban and Johansen, {Maria Vang} and Nielsen, {Henrik Vedel} and Marianne Sandberg and Anna Lund{\'e}n and Stensvold, {Christen Rune} and Pires, {Sara Monteiro} and Pikka Jokelainen",
year = "2019",
month = may,
doi = "10.1016/j.parepi.2019.e00100",
language = "English",
volume = "5",
pages = "1--13",
journal = "Parasite Epidemiology and Control",
issn = "2405-6731",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Seroprevalence of Toxoplasma gondii in domestic pigs, sheep, cattle, wild boars, and moose in the Nordic-Baltic region

T2 - A systematic review and meta-analysis

AU - Olsen, Abbey

AU - Berg, Rebecca P. K. Dorph

AU - Tagel, Maarja

AU - Must, Kärt

AU - Deksne, Gunita

AU - Enemark, Heidi Larsen

AU - Alban, Lis

AU - Johansen, Maria Vang

AU - Nielsen, Henrik Vedel

AU - Sandberg, Marianne

AU - Lundén, Anna

AU - Stensvold, Christen Rune

AU - Pires, Sara Monteiro

AU - Jokelainen, Pikka

PY - 2019/5

Y1 - 2019/5

N2 - Background Toxoplasma gondii is an important foodborne zoonotic parasite. Meat of infected animals is presumed to constitute a major source of human infection and may be a driver of geographical variation in the prevalence of anti-T. gondii antibodies in humans, which is substantial in the Nordic-Baltic region in northern Europe. However, data on seroprevalence of T. gondii in different animal species used for human consumption are scattered. Methods We conducted a systematic review of seroprevalence studies and meta-analysis to estimate the seroprevalence of T. gondii in five animal species that are raised or hunted for human consumption in the Nordic-Baltic region: domestic pigs (Sus scrofa domesticus), sheep (Ovis aries), cattle (Bos taurus), wild boars (Sus scrofa), and moose (Alces alces). We searched for studies that were conducted between January 1990 and June 2018, and reported in articles, theses, conference abstracts and proceedings, and manuscripts. Subgroup analyses were performed to identify variables influencing the seroprevalence. Findings From a total of 271 studies identified in the systematic review, 32 were included in the meta-analysis. These comprised of 13 studies on domestic pigs, six on sheep, three on cattle, six on wild boars, and four on moose. The estimated pooled seroprevalence of T. gondii was 6% in domestic pigs (CI95%: 3–10%), 23% in sheep (CI95%: 12–36%), 7% in cattle (CI95%: 1–21%), 33% in wild boars (CI95%: 26–41%), and 16% in moose (CI95%: 10–23%). High heterogeneity was observed in the seroprevalence data within each species. In all host species except wild boars, the pooled seroprevalence estimates were significantly higher in animals >1 year of age than in younger animals. Not all studies provided information on animal age, sensitivity and specificity of the serological method employed, and the cut-off values used for defining an animal seropositive. Conclusions A substantial proportion of animals raised or hunted for human consumption in the region had tested positive for T. gondii. This indicates widespread exposure to T. gondii among animals raised or hunted for human consumption in the region. Large variations were observed in the seroprevalence estimates between the studies in the region; however, studies were too few to identify spatial patterns at country-level.

AB - Background Toxoplasma gondii is an important foodborne zoonotic parasite. Meat of infected animals is presumed to constitute a major source of human infection and may be a driver of geographical variation in the prevalence of anti-T. gondii antibodies in humans, which is substantial in the Nordic-Baltic region in northern Europe. However, data on seroprevalence of T. gondii in different animal species used for human consumption are scattered. Methods We conducted a systematic review of seroprevalence studies and meta-analysis to estimate the seroprevalence of T. gondii in five animal species that are raised or hunted for human consumption in the Nordic-Baltic region: domestic pigs (Sus scrofa domesticus), sheep (Ovis aries), cattle (Bos taurus), wild boars (Sus scrofa), and moose (Alces alces). We searched for studies that were conducted between January 1990 and June 2018, and reported in articles, theses, conference abstracts and proceedings, and manuscripts. Subgroup analyses were performed to identify variables influencing the seroprevalence. Findings From a total of 271 studies identified in the systematic review, 32 were included in the meta-analysis. These comprised of 13 studies on domestic pigs, six on sheep, three on cattle, six on wild boars, and four on moose. The estimated pooled seroprevalence of T. gondii was 6% in domestic pigs (CI95%: 3–10%), 23% in sheep (CI95%: 12–36%), 7% in cattle (CI95%: 1–21%), 33% in wild boars (CI95%: 26–41%), and 16% in moose (CI95%: 10–23%). High heterogeneity was observed in the seroprevalence data within each species. In all host species except wild boars, the pooled seroprevalence estimates were significantly higher in animals >1 year of age than in younger animals. Not all studies provided information on animal age, sensitivity and specificity of the serological method employed, and the cut-off values used for defining an animal seropositive. Conclusions A substantial proportion of animals raised or hunted for human consumption in the region had tested positive for T. gondii. This indicates widespread exposure to T. gondii among animals raised or hunted for human consumption in the region. Large variations were observed in the seroprevalence estimates between the studies in the region; however, studies were too few to identify spatial patterns at country-level.

U2 - 10.1016/j.parepi.2019.e00100

DO - 10.1016/j.parepi.2019.e00100

M3 - Journal article

C2 - 30906889

VL - 5

SP - 1

EP - 13

JO - Parasite Epidemiology and Control

JF - Parasite Epidemiology and Control

SN - 2405-6731

M1 - e00100

ER -

ID: 214394905