The association between seizures and deposition of collagen in the brain in porcine Taenia solium neurocysticercosis
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
The association between seizures and deposition of collagen in the brain in porcine Taenia solium neurocysticercosis. / Christensen, Nina Møller; Trevisan, Chiara; Leifsson, Páll Skúli; Johansen, Maria Vang.
I: Veterinary Parasitology, Bind 228, 15.09.2016, s. 180-182.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - The association between seizures and deposition of collagen in the brain in porcine Taenia solium neurocysticercosis
AU - Christensen, Nina Møller
AU - Trevisan, Chiara
AU - Leifsson, Páll Skúli
AU - Johansen, Maria Vang
PY - 2016/9/15
Y1 - 2016/9/15
N2 - Neurocysticercosis caused by infection with Taenia solium is a significant cause of epilepsy and seizures in humans. The aim of this study was to assess the association between seizures and the deposition of collagen in brain tissue in pigs with T. solium neurocysticercosis. In total 78 brain tissue sections from seven pigs were examined histopathologically i.e. two pigs with epileptic seizures and T. solium cysts, four pigs without seizures but with cysts, and one non-infected control pig. Pigs with epileptic seizures had a larger amount of collagen in their brain tissue, showing as large fibrotic scars and moderate amount of collagen deposited around cysts, compared to pigs without seizures and the negative control pig. Our results indicate that collagen is likely to play a considerable part in the pathogenesis of seizures in T. solium neurocysticercosis.
AB - Neurocysticercosis caused by infection with Taenia solium is a significant cause of epilepsy and seizures in humans. The aim of this study was to assess the association between seizures and the deposition of collagen in brain tissue in pigs with T. solium neurocysticercosis. In total 78 brain tissue sections from seven pigs were examined histopathologically i.e. two pigs with epileptic seizures and T. solium cysts, four pigs without seizures but with cysts, and one non-infected control pig. Pigs with epileptic seizures had a larger amount of collagen in their brain tissue, showing as large fibrotic scars and moderate amount of collagen deposited around cysts, compared to pigs without seizures and the negative control pig. Our results indicate that collagen is likely to play a considerable part in the pathogenesis of seizures in T. solium neurocysticercosis.
U2 - 10.1016/j.vetpar.2016.09.008
DO - 10.1016/j.vetpar.2016.09.008
M3 - Journal article
C2 - 27692323
VL - 228
SP - 180
EP - 182
JO - Veterinary Parasitology
JF - Veterinary Parasitology
SN - 0304-4017
ER -
ID: 165576527