VEGF-dependent mechanism of anti-angiogenic action of diamond nanoparticles in Glioblastoma Multiforme tumor

Publikation: Bidrag til bog/antologi/rapport › Konferencebidrag i proceedings › Forskning › fagfællebedømt

Standard

VEGF-dependent mechanism of anti-angiogenic action of diamond nanoparticles in Glioblastoma Multiforme tumor. / Grodzik, M.; Sawosz, E.; Wierzbicki, M.; Hotowy, Anna Malgorzata; Prasek, M.; Jaworski, J.; Chwalibog, André.

Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy. Bind 3 NSTI Nano Science and Technology Institute, 2012. s. 218-221.

Publikation: Bidrag til bog/antologi/rapport › Konferencebidrag i proceedings › Forskning › fagfællebedømt

Harvard

Grodzik, M, Sawosz, E, Wierzbicki, M, Hotowy, AM, Prasek, M, Jaworski, J & Chwalibog, A 2012, VEGF-dependent mechanism of anti-angiogenic action of diamond nanoparticles in Glioblastoma Multiforme tumor. i Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy. bind 3, NSTI Nano Science and Technology Institute, s. 218-221.

APA

Grodzik, M., Sawosz, E., Wierzbicki, M., Hotowy, A. M., Prasek, M., Jaworski, J., & Chwalibog, A. (2012). VEGF-dependent mechanism of anti-angiogenic action of diamond nanoparticles in Glioblastoma Multiforme tumor. I Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy (Bind 3, s. 218-221). NSTI Nano Science and Technology Institute.

Vancouver

Grodzik M, Sawosz E, Wierzbicki M, Hotowy AM, Prasek M, Jaworski J o.a. VEGF-dependent mechanism of anti-angiogenic action of diamond nanoparticles in Glioblastoma Multiforme tumor. I Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy. Bind 3. NSTI Nano Science and Technology Institute. 2012. s. 218-221

Author

Grodzik, M. ; Sawosz, E. ; Wierzbicki, M. ; Hotowy, Anna Malgorzata ; Prasek, M. ; Jaworski, J. ; Chwalibog, André. / VEGF-dependent mechanism of anti-angiogenic action of diamond nanoparticles in Glioblastoma Multiforme tumor. Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy. Bind 3 NSTI Nano Science and Technology Institute, 2012. s. 218-221

Bibtex

@inproceedings{517cbc32dd9249d7a96018c31661cdb7,
title = "VEGF-dependent mechanism of anti-angiogenic action of diamond nanoparticles in Glioblastoma Multiforme tumor",
abstract = "Malignant gliomas are highly lethal cancers dependent on angiogenesis. The concept of treating tumors by inhibiting tumor angiogenesis was first articulated almost 30 years ago. Inhibition of tumor angiogenesis suppresses both tumor growth and metastasis. We determined the inhibition effect of diamond nanoparticles on the growth of brain tumor (cultured on CAM membrane) and the development of its blood vessels. We hypothesize that diamond nanoparticles can bind VEGF or their receptors and this way influence of signal transduction between cells. The aim of our study was to evaluate the influence of diamond nanoparticle on VEGF level and inhibition of the brain tumor angiogenesis. We evaluated interaction of VEGF-A and VEGF-receptor proteins with diamond nanoparticles (TEM), visualized lower the permeability of blood vessels after diamond nanoparticles treatment and determined localization in the cell and expression on protein level VEGF-A and VEGF-A-receptor.",
keywords = "Former LIFE faculty, angiogenesis, cancer, diamond, glioma, nanoparticle, VEGF",
author = "M. Grodzik and E. Sawosz and M. Wierzbicki and Hotowy, {Anna Malgorzata} and M. Prasek and J. Jaworski and Andr{\'e} Chwalibog",
year = "2012",
language = "English",
isbn = "978-.1-4665-6276-9",
volume = "3",
pages = "218--221",
booktitle = "Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy",
publisher = "NSTI Nano Science and Technology Institute",

}

RIS

TY - GEN

T1 - VEGF-dependent mechanism of anti-angiogenic action of diamond nanoparticles in Glioblastoma Multiforme tumor

AU - Grodzik, M.

AU - Sawosz, E.

AU - Wierzbicki, M.

AU - Hotowy, Anna Malgorzata

AU - Prasek, M.

AU - Jaworski, J.

AU - Chwalibog, André

PY - 2012

Y1 - 2012

N2 - Malignant gliomas are highly lethal cancers dependent on angiogenesis. The concept of treating tumors by inhibiting tumor angiogenesis was first articulated almost 30 years ago. Inhibition of tumor angiogenesis suppresses both tumor growth and metastasis. We determined the inhibition effect of diamond nanoparticles on the growth of brain tumor (cultured on CAM membrane) and the development of its blood vessels. We hypothesize that diamond nanoparticles can bind VEGF or their receptors and this way influence of signal transduction between cells. The aim of our study was to evaluate the influence of diamond nanoparticle on VEGF level and inhibition of the brain tumor angiogenesis. We evaluated interaction of VEGF-A and VEGF-receptor proteins with diamond nanoparticles (TEM), visualized lower the permeability of blood vessels after diamond nanoparticles treatment and determined localization in the cell and expression on protein level VEGF-A and VEGF-A-receptor.

AB - Malignant gliomas are highly lethal cancers dependent on angiogenesis. The concept of treating tumors by inhibiting tumor angiogenesis was first articulated almost 30 years ago. Inhibition of tumor angiogenesis suppresses both tumor growth and metastasis. We determined the inhibition effect of diamond nanoparticles on the growth of brain tumor (cultured on CAM membrane) and the development of its blood vessels. We hypothesize that diamond nanoparticles can bind VEGF or their receptors and this way influence of signal transduction between cells. The aim of our study was to evaluate the influence of diamond nanoparticle on VEGF level and inhibition of the brain tumor angiogenesis. We evaluated interaction of VEGF-A and VEGF-receptor proteins with diamond nanoparticles (TEM), visualized lower the permeability of blood vessels after diamond nanoparticles treatment and determined localization in the cell and expression on protein level VEGF-A and VEGF-A-receptor.

KW - Former LIFE faculty

KW - angiogenesis

KW - cancer

KW - diamond

KW - glioma

KW - nanoparticle

KW - VEGF

M3 - Article in proceedings

SN - 978-.1-4665-6276-9

VL - 3

SP - 218

EP - 221

BT - Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy

PB - NSTI Nano Science and Technology Institute

ER -

ID: 44560673