Kirstine Callø

Kirstine Callø

Associate Professor - Promotion Programme


  1. 2024
  2. Published

    The loss-of-function variant p.M764R in the cardiac sodium channel Nav1.5 is associated with ventricular arrhythmias and sudden cardiac death in a family without overt Brugada syndrome

    Callø, Kirstine, Christiansen, M. K., Henriksen, F. L. & Jensen, H. K., Feb 2024, In: HeartRhythm Case Reports. 10, 2, p. 137-141 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    The Nav1.5 variant G213D found in patients with MEPPC is associated with increased window current and gating pore current

    Magnusson, H. B. D., Geryk, M., Cordeiro, J. M., Lind, J. U., Jensen, H. K., Freude, Kristine & Callø, Kirstine, 16 Sep 2023.

    Research output: Contribution to conferencePosterCommunication

  5. Published

    Challenges in Establishing Animal Induced Pluripotent Stem Cells

    Enevoldsen, Sara, Magnusson, H. B. D., Lind, J. U., Freude, Kristine & Callø, Kirstine, 15 Sep 2023.

    Research output: Contribution to conferencePosterCommunication

  6. Published

    A molecular target of oxantel in whipworms

    Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Callø, Kirstine, Courtot, E., Grencis, R. K., Issouf, M., Martin, R., Neveu, C. & Charvet, C., 2023.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  7. Published

    Acute, pro-contractile effects of prorenin on rat mesenteric arteries

    Rognant, Salomé, Baldwin, S. N., Pritchard, H. A. T., Greenstein, A., Callø, Kirstine, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2023, In: FASEB Journal. 37, 12, 18 p., e23282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Intramural Purkinje fibers facilitate rapid ventricular activation in the equine heart

    Elbrønd (Bibs), Vibeke Sødring, Thomsen, Morten Bækgaard, Isaksen, Jonas L., Lunde, E. D., Vincenti, S., Wang, T., Tranum-Jensen, Jørgen & Callø, Kirstine, 2023, In: Acta Physiologica. 237, 3, e13925.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Multifocal ectopic purkinje-related premature contractions and related cardiomyopathy

    Callø, Kirstine, Magnusson, H. B. D., Lildballe, D. L., Christiansen, M. K. & Jensen, H. K., 2023, In: Frontiers in Cardiovascular Medicine. 10, 1179018.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    NHA1 is a cation/proton antiporter essential for the water-conserving functions of the rectal complex in Tribolium castaneum.

    Naseem, Muhammad Tayyib, Beaven, R., Koyama, Takashi, Naz, S., Su, S., Leader, D. P., Klærke, Dan Arne, Callø, Kirstine, Denholm, B. & Halberg, Kenneth Veland, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 13, 11 p., e2217084120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Xenobiotic Exposure and Migraine-Associated Signaling: A Multimethod Experimental Study Exploring Cellular Assays in Combination with Ex Vivo and In Vivo Mouse Models

    Rasmussen, Rikke Holm, Christensen, S. L., Callø, Kirstine, Nielsen, B. S., Rehfeld, A., Taylor-Clark, T. E., Haanes, Kristian Agmund, Taboureau, O., Audouze, K., Klærke, Dan Arne, Olesen, Jes & Kristensen, D. M., 2023, In: Environmental Health Perspectives. 131, 11, 14 p., 117003.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2022
  13. Published

    A simple and scalable 3D printing methodology for generating aligned and extended human and murine skeletal muscle tissues

    Cakal, S. D., Radeke, C., Alcala, J. F., Ellman, D. G., Butdayev, S., Andersen, D. C., Callø, Kirstine & Lind, J. U., 2022, In: Biomedical Materials (Bristol). 17, 4

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Role of ion channels in human induced pluripotent stem cells-derived cardiomyocytes

    Treat, J. A., Jankova, M., Callø, Kirstine & Cordeiro, J. M., 2022, Molecular Players in iPSC Technology. Academic Press, Vol. 12. p. 219-248 30 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  15. Published

    Takotsubo cardiomyopathy and Brugada syndrome in a patient with a novel loss-of-function variant in the cardiac sodium channel Nav1.5

    Frederiksen, T. C., Callø, Kirstine, Geryk, M. & Jensen, H. K., 2022, In: HeartRhythm Case Reports. 8, 5, p. 325-329

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The Molecular target of oxantel in whipworms

    Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Callø, Kirstine, Courtot, E., Grencis, R., Issouf, M., Martin, R., Neveu, C. & Charvet, C., 2022.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  18. 2021
  19. Published

    Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins

    Preisler, Sarah Spruce, Wiuf, A. D., Friis, M., Kjaergaard, L., Hurd, M., Becares, E. R., Nurup, C. N., Bjoerkskov, F. B., Szathmáry, Z., Gourdon, Pontus Emanuel, Callø, Kirstine, Klærke, Dan Arne, Gotfryd, K. & Pedersen, Per Amstrup, 2021, In: Current research in structural biology. 3, p. 51-71 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Evaluation of electrocardiographic repolarization parameters after administration of trimethoprim-sulfadiazine, detomidine, or their combination in horses

    Trachsel, D. S., Callø, Kirstine, Jørgensen, Elin , Lunddahl, C. S., Pedersen, P. J., Kanters, Jørgen K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: American Journal of Veterinary Research. 82, 3, p. 207-217 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Exercise-Associated Sudden Death in Finnish Standardbred and Coldblooded Trotters - A Case Series With Pedigree Analysis

    Trachsel, D. S., Callø, Kirstine, Mykkänen, A. K., Raistakka, P., Anttila, M., Fredholm, Merete, Tala, M., Lamminpää, K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: Journal of Equine Veterinary Science. 104, 103694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Quantitative proteome comparison of human hearts with those of model organisms

    Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The narrow-spectrum anthelmintic oxantel is a potent agonist of a novel acetylcholine receptor subtype in whipworms

    Hansen, Tina Vicky Alstrup, Cirera, Susanna, Neveu, C., Courtot, E., Charvet, C. L., Callø, Kirstine, Klærke, Dan Arne & Martin, R. J., 2021, In: P L o S Pathogens. 17, 2, 26 p., e1008982.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2020
  25. Published

    Cloning and Expression of an Oxantel Sensitive Homomeric Nicotinic Acetylcholine Receptor of Trichuris, the Tsu-ACR-16-like receptor

    Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Neveu, C., Callø, Kirstine & Martin, R., 2020.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  26. 2019
  27. Published

    PACAP-38 and PACAP(6-38) degranulate rat meningeal mast cells via the orphanMrgB3-receptor

    Pedersen, S. H., la Cour, S. H., Callø, Kirstine, Hauser, Frank, Olesen, Jes, Klærke, Dan Arne & Jansen-Olesen, I., Sep 2019, p. 4-4.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  28. Published

    Acquired LQTS in horses

    Callø, Kirstine, Trachsel, D. S., Rognant, Salomé, Friis, S., Pedersen, P. J. & Klærke, Dan Arne, 8 Aug 2019.

    Research output: Contribution to conferencePosterCommunication

  29. Published

    Cardiac repolarization in horses

    Klærke, Dan Arne, Trachsel, D. S., Buhl, Rikke, Pedersen, P. J. & Callø, Kirstine, 8 Aug 2019.

    Research output: Contribution to conferencePosterCommunication

  30. Published

    Doctoral Dissertation: The transient outward potassium current in healthy and diseased hearts

    Callø, Kirstine, Jan 2019, In: Acta Physiologica. 225 , S717, e13225.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Comparison of cultured human cardiomyocyte clusters obtained from embryos/fetuses or derived from human embryonic stem cells

    Grubb, Søren, Vestergaard, M. L., Andersen, A. S., Rasmussen, K. K., Mamsen, L., Tuckute, G., Grunnet-Lauridsen, K., Møllgård, Kjeld, Ernst, E., Christensen, Søren Tvorup, Callø, Kirstine & tcg964, tcg964, 2019, In: Stem Cells and Development. 28, 9, p. 608-619

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel K v 11.1

    Callø, Kirstine, Rognant, Salomé, Friis, S., Shaughnessy, C., Klærke, Dan Arne & Trachsel, D., 2019, In: Research in Veterinary Science. 123, p. 239-246 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    PACAP-38 and PACAP(6-38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB3-Receptor

    Pedersen, S. H., la Cour, S. H., Callø, Kirstine, Hauser, Frank, Olesen, Jes, Klærke, Dan Arne & Jansen-Olesen, I., 2019, In: Frontiers in Cellular Neuroscience. 13, 11 p., 114.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Purification of Functional Human TRP Channels Recombinantly Produced in Yeast

    Zhang, L., Wang, Kaituo, Klærke, Dan Arne, Callø, Kirstine, Lowrey, L., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2019, In: Cells. 8, 2, p. 1-20 148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Structure of the human ClC-1 chloride channel

    Wang, Kaituo, Preisler, Sarah Spruce, Zhang, L., Cui, Y., Missel, Julie Winkel, Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The Transient Outward Potassium Current in Healthy and Diseased Hearts

    Callø, Kirstine, 2019, Københavns Universitet.

    Research output: Book/ReportDoctoral thesisResearch

  37. 2018
  38. Published

    Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Nav1.5 gain-of-function mutation (G213D)

    Callø, Kirstine, Broendberg, A. K., Christensen, A. H., Pedersen, L. N., Olesen, Morten Steen Salling, de Los Angeles Tejada, M., Friis, S., Thomsen, Morten Bækgaard, Bundgård, Henning & Jensen, H. K., 15 Apr 2018, In: International Journal of Cardiology. 257, p. 160-167 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Effects of trimethoprim–sulfadiazine and detomidine on the function of equine Kv11.1 channels in a two-electrode voltage-clamp (TEVC) oocyte model

    Trachsel, D. S., Tejada, M. A., Groesfjeld Christensen, V., Pedersen, P. J., Kanters, Jørgen K., Buhl, Rikke, Callø, Kirstine & Klærke, Dan Arne, 2018, In: Journal of Veterinary Pharmacology and Therapeutics. 41, 4, p. 536-545 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Interventricular differences in sodium current and its potential role in Brugada syndrome

    Callø, Kirstine, Aistrup, G. L., Di Diego, J. M., Goodrow, R. J., Treat, J. A. & Cordeiro, J. M., 2018, In: Physiological Reports. 6, 14, 12 p., e13787.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers

    Klærke, Dan Arne, Tejada, M. D. L. A., Christensen, V. G., Lassen, M., Pedersen, Per Amstrup & Callø, Kirstine, 2018, In: Current Protocols in Pharmacology. 81, 1, p. e37 17 p., e37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2017
  43. Published

    Human embryonic stem cell derived cardiomyocytes self-arrange with areas of different subtypes during differentiation

    Vestergaard, M. L., Grubb, Søren, Rasmussen, K. K., Anderson-Jenkins, Z. L., Grunnet-Lauridsen, K., Callø, Kirstine, Clausen, C., Christensen, Søren Tvorup, Møllgård, Kjeld & tcg964, tcg964, 1 Nov 2017, In: Stem Cells and Development. 26, 21, p. 1566-1577 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Molecular cloning and functional expression of the K+ channel KV7.1 and the regulatory subunit KCNE1 from equine myocardium: [Inkl. corrigendum]

    Pedersen, P. J., Thomsen, K. B., Flak, J. B., Tejada, M. D. L. A., Hauser, Frank, Trachsel, D. S., Buhl, Rikke, Kalbfleisch, T., DePriest, M. S., MacLeod, J. N., Callø, Kirstine & Klærke, Dan Arne, Aug 2017, In: Research in Veterinary Science. 113, p. 79-86 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Ventricular repolarization time, location of pacing stimulus and current pulse amplitude conspire to determine arrhythmogenicity in mice

    Speerschneider, T., Grubb, Søren, Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 9 Feb 2017, In: Acta Physiologica. 219, 3, p. 662-670 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Heteromeric Slick/Slack K+ channels show graded sensitivity to cell volume changes

    Tejada, M. A., Hashem, N., Callø, Kirstine & Klærke, Dan Arne, 2017, In: PLOS ONE. 12, 2, 11 p., e0169914.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B

    Zhang, Y., Schmid, B., Qas Younan, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA. & 4 others, Holst, B., Clausen, C., Hyttel, P. & Freude, Kristine, 2017, In: Stem Cell Reports. 8, 3, p. 648-658

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Single-Channel Recordings of K+ Channels Expressed in Saccharomyces Cerevisiae

    Tejada, M. D. L. A., Molbaek, K., Cazimi, H., Ellekvist, P., Callø, Kirstine, Nielsen, C. H., Pedersen, Per Amstrup & Klærke, Dan Arne, 2017, In: Biophysical Journal. 112, 3, Suppl. 1, p. 406A 1 p., 2002-Pos Board B322.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  49. 2016
  50. Published

    A dual potassium channel activator improves repolarization reserve and normalizes ventricular action potentials

    Callø, Kirstine, Di Diego, J. M., Hansen, R. S., Nagle, S. A., Treat, J. A. & Cordeiro, J. M., 19 Mar 2016, In: Biochemical Pharmacology. 108, p. 36-46 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Human atrial fibroblasts and their contribution to supraventricular arrhythmia

    Thomsen, Morten Bækgaard & Callø, Kirstine, Feb 2016, In: Physiological Reports. 4, 3, 3 p., e12711.

    Research output: Contribution to journalEditorialResearchpeer-review

  52. Published

    Physiological roles of the transient outward current Ito in normal and diseased hearts

    Cordeiro, J. M., Callø, Kirstine, Aschar-Sobbi, R., Kim, K., Korogyi, A., Occhipinti, D., Backx, P. H. & Panama, B. K., 1 Jan 2016, In: Frontiers in bioscience (Scholar edition). 8, p. 143-159 17 p., 454.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2015
  54. Published

    The Mutation P.T613a in the Pore Helix of the Kv 11.1 Potassium Channel is Associated with Long Qt Syndrome

    Poulsen, K. L., Hotait, M., Callø, Kirstine, Klærke, Dan Arne, Rebeiz, A., Nemer, G., Tejada, M. A. & Refaat, M. M., Nov 2015, In: Pacing and Clinical Electrophysiology. 38, 11, p. 1304–1309 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2

    Grubb, Søren, Aistrup, G. L., Koivumäki, J. T., Speerschneider, T., Gottlieb, Lisa Amalie, Mutsaers, N. A. M., Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H481-H489 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

    Axelsen, L. N., Callø, Kirstine, Braunstein, T. H., Riemann, Mads, Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, Kristine Boisen, Bartels, Emil Daniel, Baandrup, U., Jespersen, Thomas, Nielsen, L. B., von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    High incidence of functional ion-channel abnormalities in a consecutive Long QT cohort with novel missense genetic variants of unknown significance

    Steffensen, Annette Buur, Refaat, M. M., David, J., Mujezinovic, A., Callø, Kirstine, Wojciak, J., Nussbaum, R. L., Scheinman, M. M. & Schmitt, Nicole, 12 Jun 2015, In: Scientific Reports. 5, p. 1-13 13 p., 10009.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Action potential repolarization in equine hearts

    Callø, Kirstine, Pedersen, P. J., Tejada, M. D. L. A., Poulsen, K. L., Grubb, Søren, Buhl, Rikke & Klærke, Dan Arne, 2015, In: Biophysical Journal. 108, 2, Supplement 1, p. 113a 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  59. Published

    Molecular cloning and functional expression of the Equine K+ channel KV11.1 (Ether à Go-Go-related/KCNH2 gene) and the regulatory subunit KCNE2 from equine myocardium

    Pedersen, P. J., Thomsen, K. B., Olander, E. R., Hauser, Frank, Tejada, M. D. L. A., Poulsen, K. L., Grubb, Søren, Buhl, Rikke, Callø, Kirstine & Klærke, Dan Arne, 2015, In: PloS one. 10, 9, 19 p., e0138320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. 2014
  61. Published

    NS5806 partially restores action potential duration but fails to ameliorate calcium transient dysfunction in a computational model of canine heart failure

    Maleckar, M. M., Lines, G. T., Koivumäki, J. T., Cordeiro, J. M. & Callø, Kirstine, Nov 2014, In: Europace. 16, suppl. 4, p. iv46-iv55 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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