Kristine Freude

Kristine Freude

Professor


Publication year:
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1 - 25 out of 111Page size: 25
  1. 2024
  2. Published

    Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy

    Kamand, M., Taleb, R., Wathikthinnakon, Methi, Mohamed, Fadumo Abdullahi, Ghanzanfari, S. P., Konstantinov, D., Hald, Jonas Laugård, Holst, B., Andersen, C. B., Møller, R. S., Lemke, J. R., Krey, I., Freude, Kristine & Chandrasekaran, Abinaya, 1 Apr 2024, In: Stem Cell Research. 76

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    APOE4 IS INSTRUMENTAL IN AUGMENTING RHOA KINASE PHOSPHORYLATION AND CONTRIBUTES THEREBY TO CLASSICAL ALZHEIMER’S DISEASE NEURON PHENOTYPES

    Freude, Kristine, Dittlau, Katarina Stoklund & Tao, Ruixin, 5 Mar 2024.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  4. Published

    Astrocytes: The Stars in Neurodegeneration?

    Dittlau, Katarina Stoklund & Freude, Kristine, 28 Feb 2024, In: Biomolecules.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Implications of SNP-triggered miRNA dysregulation in Schizophrenia development

    Mohamed, Fadumo Abdullahi & Freude, Kristine, 26 Jan 2024, In: Frontiers in Genetics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    USP30 inhibition induces mitophagy and reduces oxidative stress in parkin-deficient human neurons

    Okarmus, J., Agergaard, J. B., Stummann, T., Haukedal, H., Ambjørn, M., Freude, Kristine, Fog, K. & Meyer, M., 14 Jan 2024, In: Nature.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Fordele og ulemper ved anvendelse af autologe versus allogene stamceller til behandling af artrose

    Bagge, J., Freude, Kristine, Lindegaard, Casper, Holst, B. & Hölmich, Per, 2024, In: Ugeskrift for Laeger. 186, 7 p., V06230423.

    Research output: Contribution to journal › Journal article › Communication

  8. Published

    Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies

    Dittlau, Katarina Stoklund, Chandrasekaran, Abinaya, Freude, Kristine & Van Den Bosch, L., 2024, In: Bio-protocol. 14, 4, 16 p., e4936.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus

    Duque Villegas, Luisana Carolina, Chandrasekaran, Abinaya, Flintholm Andersen, S. A., Nørremølle, Anne, Schmid, B., Pouladi, M. A. & Freude, Kristine, 2024, In: Stem Cell Research. 77, 6 p., 103408.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. E-pub ahead of print

    Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease

    Salcedo, C., Pozo Garcia, V., Garcia-Adan, B., Ameen, Aisha, Gegelashvili, G., Waagepetersen, Helle S., Freude, Kristine & Aldana, Blanca, 2024, (E-pub ahead of print) In: Journal of Neurochemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2023
  12. Published

    The Nav1.5 variant G213D found in patients with MEPPC is associated with increased window current and gating pore current

    Magnusson, H. B. D., Geryk, M., Cordeiro, J. M., Lind, J. U., Jensen, H. K., Freude, Kristine & Callø, Kirstine, 16 Sep 2023.

    Research output: Contribution to conference › Poster › Communication

  13. Published

    Challenges in Establishing Animal Induced Pluripotent Stem Cells

    Enevoldsen, Sara, Magnusson, H. B. D., Lind, J. U., Freude, Kristine & Callø, Kirstine, 15 Sep 2023.

    Research output: Contribution to conference › Poster › Communication

  14. Published

    Complexity of Sex Differences and Their Impact on Alzheimer’s Disease

    Kadlecová, Marion, Freude, Kristine & Haukedal, H., 24 Apr 2023, In: Biomedicines. 11, 5, 29 p., 1261.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    3D-organization and spatial localization of chromatin and epigenetic marks in relation to nucleolar activity in porcine oocytes

    Fenner, Merle Friederike, Benc, M., Rosenbaum Bartkova , A., Pihl, M., Chebrout, M., Freude, Kristine, Strejeck, F., Hyttel, P., Lucas-Hahn, A., Laurincik, J. & Bonnet-Garnier, A., 2023. 1 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  16. Published

    FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms

    Dittlau, Katarina Stoklund, Terrie, L., Baatsen, P., Kerstens, A., De Swert, L., Janky, R., Corthout, N., Masrori, P., Van Damme, P., Hyttel, P., Meyer, M., Thorrez, L., Freude, Kristine & Van Den Bosch, L., 2023, In: Molecular Neurodegeneration. 18, 1, 5.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3

    Haukedal, H., Syshøj Lorenzen, S., Westi, Emil Winther, Corsi, G., Gadekar, V. P., McQuade, A., Davtyan, H., Doncheva, Nadezhda Tsankova, Schmid, B., Chandrasekaran, Abinaya, Seemann, Ernst Stefan, Cirera, Susanna, Blurton-Jones, M., Meyer, M., Gorodkin, Jan, Aldana, Blanca & Freude, Kristine, 2023, In: Brain, Behavior, and Immunity. 113, p. 353-373

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Chromatin organization, spatial localization of heterochromatin sequences and nucleolar activity, change towards final maturation in porcine oocytes

    Bonnet-Garnier, A., Benc, M., Bartkova, A., Pihl, M., Chebrout, M., Strejcek, F., Hyttel, P., Lucas-Hahn, A., Laurincik, J., Freude, Kristine & Fenner, Merle Friederike, 2023. 1 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  19. Published

    Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology

    Rivera-Sánchez, P., Søndergaard, L., Wathikthinnakon, Methi, B. D. Magnusson, H., Frederiksen, Henriette Reventlow S, Aabæk Hammer, F., Taleb, R., Christian Cassidy, C., Tranholm Bruun, M., Tümer, Asuman Zeynep, Holst, B., Brasch-Andersen, C., Møller, R., Freude, Kristine & Chandrasekaran, Abinaya, 2023, In: Stem Cell Research. 71, 103193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Golgi fragmentation: One of the earliest organelle phenotypes in Alzheimer's disease neurons

    Haukedal, H., Corsi, G. I., Gadekar, V. P., Doncheva, N. T., Kedia, S., de Haan, N., Chandrasekaran, A., Jensen, P., Schiønning, P., Vallin, S., Marlet, F. R., Poon, A., Pires, C., Agha, F. K., Wandall, H. H., Cirera, S., Simonsen, A. H., Nielsen, T. T., Nielsen, J. E., Hyttel, P. & 7 others, Muddashetty, R., Aldana, Blanca, Gorodkin, Jan, Nair, D., Meyer, M., Larsen, M. R. & Freude, Kristine, 2023, In: Frontiers in Neuroscience. 17, 17 p., 1120086.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Potential Retinal Biomarkers in Alzheimer's Disease

    Garcia Bermudez, Mariana Yolotzin, Vohra, Rupali, Freude, Kristine, van Wijngaarden, P., Martin, K. K., Thomsen, M. S., Aldana, Blanca & Kolko, Miriam, 2023, In: International Journal of Molecular Sciences (Online). 24, 21, 26 p., 15834.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Role of S1P-receptor and Rho-kinase in myogenic tone in mesenteric and cerebral arteries of young vs. middle-aged mice

    Skovsted, Gry Freja, Aupetit, A., Björling , K., Haanes, K. A., Syberg, S., Jørgensen, N. R., Freude, Kristine, Pearson, J. T. & Jensen, Lars Jørn, 2023, In: Acta Physiologica. 239, S728, e14042.

    Research output: Contribution to journal › Conference abstract in journal › Communication

  23. Published

    The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression

    Corsi, G. I., Gadekar, V. P., Haukedal, H., Doncheva, Nadezhda Tsankova, Anthon, Christian, Ambardar, S., Palakodeti, D., Hyttel, P., Freude, Kristine, Seemann, Ernst Stefan & Gorodkin, Jan, 2023, In: Neurobiology of Disease. 178, 17 p., 105980.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2022
  25. Published

    Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease

    Tams, A. L. M., Sanz-Morello, B., Westi, Emil Winther, Mouhammad, Zaynab Ahmad, Andersen, Jens Velde, Freude, Kristine, Vohra, Rupali, Hannibal, Jens, Aldana, Blanca & Kolko, Miriam, 2022, In: Cellular and Molecular Neurobiology. 42, 1, p. 291–303

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Editorial: Metabolic Alterations in Neurodegenerative Disorders

    Freude, Kristine, Moreno-gonzalez, I., Rodriguez-ortiz, C. J. & Baglietto-vargas, D., 2022, In: Frontiers in Aging Neuroscience. 14, 3 p., 833109.

    Research output: Contribution to journal › Editorial › Research › peer-review

  27. Published

    Fats, Friends or Foes: Investigating the Role of Short- and Medium-Chain Fatty Acids in Alzheimer’s Disease

    Ameen, Aisha, Freude, Kristine & Aldana, Blanca, 2022, In: Biomedicines. 10, 11, 2778.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop: Effect on cultured human conjunctival goblet cells and their physicochemical properties

    Nagstrup, Anne Hedengran, Freiberg, Josefine, Hansen, Pernille May, Jacobsen, Jette, Larsen, Susan Weng, Rønholt, Stine, Freude, Kristine, Boix‐lemonche, G., Petrovski, G., Heegaard, Steffen & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, 7, p. 819-827

    Research output: Contribution to journal › Journal article › Research › peer-review

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