Pathobiological Sciences

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  1. 2024
  2. Published

    Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy

    Kamand, M., Taleb, R., Wathikthinnakon, Methi, Mohamed, Fadumo Abdullahi, Ghanzanfari, S. P., Konstantinov, D., Hald, Jonas Laugård, Holst, B., Andersen, C. B., Møller, R. S., Lemke, J. R., Krey, I., Freude, Kristine & Chandrasekaran, Abinaya, 1 Apr 2024, In: Stem Cell Research. 76

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Turning the tables – An optimized supervision model for master thesis students from the students’ perspective

    Pingel, Jessica, 8 Mar 2024, https://tidsskrift.dk.

    Research output: Other contribution › Communication

  4. Published

    APOE4 IS INSTRUMENTAL IN AUGMENTING RHOA KINASE PHOSPHORYLATION AND CONTRIBUTES THEREBY TO CLASSICAL ALZHEIMER’S DISEASE NEURON PHENOTYPES

    Freude, Kristine, Dittlau, Katarina Stoklund & Tao, Ruixin, 5 Mar 2024.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  5. Published

    Astrocytes: The Stars in Neurodegeneration?

    Dittlau, Katarina Stoklund & Freude, Kristine, 28 Feb 2024, In: Biomolecules.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Functional, Structural and Proteomic Effects of Ageing in Resistance Arteries

    Jensen, Lars Jørn, 23 Feb 2024, 22 p. MDPI - Open Access Publishing.

    Research output: Other contribution › Research

  7. Published

    Grise med små navlebuler kan nå frem til slagtning: I to besætninger med mange grise med navlebuler nåede 41 procent af grisene med navlebule frem til slagtning

    Thorup, F., Christiansen, M. G., Jensen, Henrik Elvang & Hovmand-Hansen, T., 1 Feb 2024, In: Magasinet Gris.

    Research output: Contribution to journal › Journal article › Communication

  8. Published

    The loss-of-function variant p.M764R in the cardiac sodium channel Nav1.5 is associated with ventricular arrhythmias and sudden cardiac death in a family without overt Brugada syndrome

    Callø, Kirstine, Christiansen, M. K., Henriksen, F. L. & Jensen, H. K., Feb 2024, In: HeartRhythm Case Reports. 10, 2, p. 137-141 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Implications of SNP-triggered miRNA dysregulation in Schizophrenia development

    Mohamed, Fadumo Abdullahi & Freude, Kristine, 26 Jan 2024, In: Frontiers in Genetics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    USP30 inhibition induces mitophagy and reduces oxidative stress in parkin-deficient human neurons

    Okarmus, J., Agergaard, J. B., Stummann, T., Haukedal, H., Ambjørn, M., Freude, Kristine, Fog, K. & Meyer, M., 14 Jan 2024, In: Nature.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. E-pub ahead of print

    Atrial fibrillation as a risk factor for exercise-induced pulmonary haemorrhage following a standardised exercise test

    Hansen, Sanni, Dam Otten, Nina, Nissen, Sarah Dalgas, Carstensen, Helena, Hopster-Iversen, Charlotte, Fjeldborg, Julie, Staun, S. H., Fenner, Merle Friederike, Hesselkilde, E. M. & Buhl, Rikke, 2024, (E-pub ahead of print) In: Equine Veterinary Journal.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Catheter-associated bladder mucosal trauma during intermittent voiding: An experimental study in pigs

    Stærk, K., Schrøder, B., Jensen, Louise Kruse, Petersen, T., Andersen, T. E. & Nielsen, L. F., 2024, In: BJUI Compass. 5, 2, p. 217-223 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Charting the Explicit Path: Translational Dynamics of Hepatic Bioengineering from Experimental Benchmarks to Practical Bedside Applications

    Radhakrishnan, S., Martin, C. A., Dhayanithy, G., Martin, J. C., Chandrasekaran, Abinaya, Kalkura, S. N. & Rela, M., 2024, In: MedLiber of Regenerative Medicine. 2, 1, p. 1-18

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Clinicopathologic evaluation of congenital idiopathic megaesophagus in a Gordon Setter puppy: a case report and development and application of peripherin immunohistochemistry for detection of ganglion cells

    Becker, Cecilie Brandt & Jensen, Henrik Elvang, 2024, In: Journal of Veterinary Diagnostic Investigation. 36, 2, p. 254-257 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Distinct Metabolic Profiles of Ocular Hypertensives in Response to Hypoxia

    Langbøl, Mia Aggergaard, Rovelt, Jens, Saruhanian, A., Saruhanian, S., Tiedemann, D., Baskaran, T., Bocca, C., Vohra, Rupali, Cvenkel, B., Lenaers, G. & Kolko, Miriam, 2024, In: International Journal of Molecular Sciences. 25, 1, 18 p., 195.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. E-pub ahead of print

    Equine dental sinusitis—A statistical analysis of the effect of antibiotics on dental sinusitis following dental extraction

    Lydiksen, C. V., Christensen, J. I., Rosenmeier, J. G., Jensen, Dan Børge & Lindegaard, Casper, 2024, (E-pub ahead of print) In: Equine Veterinary Education.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Fordele og ulemper ved anvendelse af autologe versus allogene stamceller til behandling af artrose

    Bagge, J., Freude, Kristine, Lindegaard, Casper, Holst, B. & Hölmich, Per, 2024, In: Ugeskrift for Laeger. 186, 7 p., V06230423.

    Research output: Contribution to journal › Journal article › Communication

  18. Published

    Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies

    Dittlau, Katarina Stoklund, Chandrasekaran, Abinaya, Freude, Kristine & Van Den Bosch, L., 2024, In: Bio-protocol. 14, 4, 16 p., e4936.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus

    Duque Villegas, Luisana Carolina, Chandrasekaran, Abinaya, Flintholm Andersen, S. A., Nørremølle, Anne, Schmid, B., Pouladi, M. A. & Freude, Kristine, 2024, In: Stem Cell Research. 77, 6 p., 103408.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    High fat diet is associated with gut microbiota dysbiosis and decreased gut microbial derived metabolites related to metabolic health in young Göttingen Minipigs

    Lützhøft, Ditte Olsen, Bækgård, Cecilie, Wimborne, E., Straarup, E. M., Pedersen, K. M., Swann, J. R., Pedersen, H. D., Kristensen, K., Morgills, L., Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Bracken, M. K., Cirera, Susanna & Christoffersen, B. Ø., 2024, In: PLoS ONE. 19, 3, 27 p., e0298602.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. E-pub ahead of print

    Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease

    Salcedo, C., Pozo Garcia, V., Garcia-Adan, B., Ameen, Aisha, Gegelashvili, G., Waagepetersen, Helle S., Freude, Kristine & Aldana, Blanca, 2024, (E-pub ahead of print) In: Journal of Neurochemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Intraoperative tissue sampling for histology in chronic osteomyelitis shows high neutrophil infiltration centrally and low remains in debrided presumed infection-free regions

    Jensen, Louise Kruse, Jensen, Henrik Elvang & Gottlieb, Hans, 2024, In: Injury. 55, 2, 6 p., 111178.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Migratory pattern of zoonotic Toxocara cati and T. canis in experimentally infected pigs

    Poulsen, C. S., Yoshida, A., Wellbrant, T. T., Leifsson, Páll S., Skallerup, P., Thamsborg, Stig Milan & Nejsum, P., 2024, In: European Journal of Clinical Microbiology and Infectious Diseases. 43, p. 587-596 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Pathological Diagnosis of Pulmonary Aspergillosis

    Jensen, Henrik Elvang & Becker, Cecilie Brandt, 2024, In: Seminars in Respiratory and Critical Care Medicine. 45, 1, p. 41-49

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Rifampicin does not reduce moxifloxacin concentrations at the site of infection and may not improve treatment outcome of a one-stage exchange surgery protocol of implant-associated osteomyelitis lesions in a porcine model

    Vittrup, S., Jensen, Louise Kruse, Hartmann, Katrine Top, Aalbæk, Bent, Hanberg, P., Slater, J., Hvistendahl, M. A., Stilling, M., Jørgensen, N. P. & Bue, M., 2024, In: APMIS. 132, 3, p. 198-209 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The avian influenza A virus receptor SA-α2,3-Gal is expressed in the porcine nasal mucosa sustaining the pig as a mixing vessel for new influenza viruses

    Kristensen, Charlotte, Larsen, Lars, Trebbien, R. & Jensen, Henrik Elvang, 2024, In: Virus Research. 340, 8 p., 199304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2023
  28. Published

    The Nav1.5 variant G213D found in patients with MEPPC is associated with increased window current and gating pore current

    Magnusson, H. B. D., Geryk, M., Cordeiro, J. M., Lind, J. U., Jensen, H. K., Freude, Kristine & Callø, Kirstine, 16 Sep 2023.

    Research output: Contribution to conference › Poster › Communication

  29. Published

    Challenges in Establishing Animal Induced Pluripotent Stem Cells

    Enevoldsen, Sara, Magnusson, H. B. D., Lind, J. U., Freude, Kristine & Callø, Kirstine, 15 Sep 2023.

    Research output: Contribution to conference › Poster › Communication

  30. Published

    SKIN ULCERATIONS IN DANISH NURSERY PIGS

    Barington, Kristiane, Pankoke, K., Hartmann, Katrine Top, Hansen, Mette Sif, Jensen, Henrik Elvang, Blirup-Plum, Sophie Amalie, Jørgensen, B. M., Nielsen, Jens Peter, Eriksen, E. Ø., Kudirkiene, E., Olsen, John Elmerdahl & Pedersen, Ken Steen, 30 Aug 2023.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  31. Published

    A SEVERE OUTBREAK OF COLIBACILLOSIS IN BROILERS

    Kromann, Sofie, Baig, S. J., Olsen, Rikke Heidemann, Edslev, S. M., Thoefner, Ida , Bojesen, Anders Miki, Jensen, Henrik Elvang & Stegger, M., 29 Aug 2023.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  32. Published

    Complexity of Sex Differences and Their Impact on Alzheimer’s Disease

    Kadlecová, Marion, Freude, Kristine & Haukedal, H., 24 Apr 2023, In: Biomedicines. 11, 5, 29 p., 1261.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Universiteterne har brug for en reformpause

    Kropp, K., Vallgårda, Karen Asta Arnfred, Hougaard Laustsen-Kiel, A., Albrechtsen, Nicolai Jacob Wewer, Sylow, Lykke, Damgaard, R. B., Kristensen, Line Burholt, Hansen, N. C., Uusimäki, E., Jønsson, A. B., Høyland-Kroghsbo, Nina Molin, Eriksen, J. J., Rasmussen, Laura Vang, Andersen, P. E., Jensen, Louise Kruse, Lomborg, Stine, Morueta-Holme, Naia, Simonsen, K. B., Zetterberg-Nielsen, S. & Autzen, A., 29 Jan 2023, In: Berlingske Tidende.

    Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication

  34. Published

    3D-organization and spatial localization of chromatin and epigenetic marks in relation to nucleolar activity in porcine oocytes

    Fenner, Merle Friederike, Benc, M., Rosenbaum Bartkova , A., Pihl, M., Chebrout, M., Freude, Kristine, Strejeck, F., Hyttel, P., Lucas-Hahn, A., Laurincik, J. & Bonnet-Garnier, A., 2023. 1 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  35. Published

    FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms

    Dittlau, Katarina Stoklund, Terrie, L., Baatsen, P., Kerstens, A., De Swert, L., Janky, R., Corthout, N., Masrori, P., Van Damme, P., Hyttel, P., Meyer, M., Thorrez, L., Freude, Kristine & Van Den Bosch, L., 2023, In: Molecular Neurodegeneration. 18, 1, 5.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    A molecular target of oxantel in whipworms

    Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Callø, Kirstine, Courtot, E., Grencis, R. K., Issouf, M., Martin, R., Neveu, C. & Charvet, C., 2023.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  37. Published

    Acute, pro-contractile effects of prorenin on rat mesenteric arteries

    Rognant, Salomé, Baldwin, S. N., Pritchard, H. A. T., Greenstein, A., Callø, Kirstine, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2023, In: FASEB Journal. 37, 12, 18 p., e23282.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3

    Haukedal, H., Syshøj Lorenzen, S., Westi, Emil Winther, Corsi, G., Gadekar, V. P., McQuade, A., Davtyan, H., Doncheva, Nadezhda Tsankova, Schmid, B., Chandrasekaran, Abinaya, Seemann, Ernst Stefan, Cirera, Susanna, Blurton-Jones, M., Meyer, M., Gorodkin, Jan, Aldana, Blanca & Freude, Kristine, 2023, In: Brain, Behavior, and Immunity. 113, p. 353-373

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals

    Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Feng, S., Marichal-Gallardo, P., Holmbeck, Kenn, Pihl, A. F., Fernandez-Antunez, C., Alzua, G. P., Hartmann, Katrine Top, Pham, Long, Zhou, Y., Gammeltoft, Karen Anbro, Fahnøe, Ulrik, Schneider, Uffe Vest, Pedersen, Gabriel Kristian, Jensen, Henrik Elvang, Christensen, Jan Pravsgaard, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: iScience. 26, 2, 105949.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    An observational field study of porcine post-weaning diarrhea: clinical and microbiological findings, and fecal pH-measurements as a potential diagnostic tool

    Eriksen, E. Ø., Kudirkiene, E., Barington, Kristiane, Goecke, Nicole Bakkegård, Blirup-Plum, Sophie Amalie, Nielsen, Jens Peter, Olsen, John Elmerdahl, Jensen, Henrik Elvang, Pankoke, K., Larsen, Lars, Liu, G. & Pedersen, Ken Steen, 2023, In: Porcine Health Management. 9, 33.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Bacterial invasion of the submicron osteocyte lacuna–canaliculi network (OLCN): a part of osteomyelitis disease biology

    Jensen, Louise Kruse, Birch, Julie Knippel Melsted, Jensen, Henrik Elvang, Kirketerp-Møller, K. & Gottlieb, Hans, 2023, In: APMIS. 131, 7, p. 325-332

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Biomekanik - Funktionel Anatomi: Kompendium i biomekanik til veterinærstuderende

    Elbrønd (Bibs), Vibeke Sødring, 2023, 8 p.

    Research output: Book/Report › Compendium/lecture notes › Education

  43. Published

    CONGENITAL IDIOPATHIC MEGAOESOPHAGUS IN A 5 WEEK OLD FEMALE GORDON SETTER PUPPY

    Becker, Cecilie Brandt & Jensen, Henrik Elvang, 2023.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  44. Published

    Characterization of high pathogenicity avian influenza H5Nx viruses from a wild harbor seal and red foxes in Denmark, 2021 and 2022: Characterization of high pathogenicity avian influenza H5Nx viruses from a wild harbor seal and red foxes in Denmark, 2021 and 2022

    Liang, Yuan, Hjulsager, C. K., Jensen, Tim Kåre, Hammer, Anne Sofie Vedsted, Ovesen, Maibritt Træholt & Larsen, Lars, 2023, In: Influenza and other Respiratory Viruses. 17, 10, 10 p., e13208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Chromatin organization, spatial localization of heterochromatin sequences and nucleolar activity, change towards final maturation in porcine oocytes

    Bonnet-Garnier, A., Benc, M., Bartkova, A., Pihl, M., Chebrout, M., Strejcek, F., Hyttel, P., Lucas-Hahn, A., Laurincik, J., Freude, Kristine & Fenner, Merle Friederike, 2023. 1 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  46. Published

    Co-localization of influenza A virus and voltage-dependent calcium channels provides new perspectives on the internalization process in pigs

    Kristensen, Charlotte, Jensen, Henrik Elvang, Trebbien, R., Ryt-Hansen, Pia & Larsen, Lars, 2023, In: npj Viruses. 1, 7 p., 8.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Comparing video examinations with physical clinical examinations using finishing pigs with umbilical outpouchings as a model

    Birch, Julie Knippel Melsted & Pedersen, Ken Steen, 2023, In: Acta Veterinaria Scandinavica. 65, 26.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Composition of mucus- and digesta-associated bacteria in growing pigs with and without diarrhea differed according to the presence of colonic inflammation

    Panah, F. M., Lauridsen, C., Højberg, O., Jensen, Henrik Elvang & Nielsen, T. S., 2023, In: BMC Microbiology. 23, 18 p., 145.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Computed Tomography as a Method for Age Determination of Carnivora and Odontocetes with Validation from Individuals with Known Age

    Baier-Stegmaier, S., Gundlach, C., Chriél, M., Hansen, Mette Sif, Vedel-Smith, C., Hansen, C. V., Johansson, D. K., Henriksen, L. B., Wahlberg, M., Thøstesen, C. B., Alstrup, A. K. O., Gregersen, K. M., Pertoldi, C. & Pagh, S., 2023, In: Animals. 13, 11, 1783.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Cystitis: significant associations between pathology, histology, and quantitative bacteriology in sows, a cross-sectional study

    Tolstrup, L. K., Leifsson, Páll S., Guardabassi, Luca, Nielsen, Jens Peter & Pedersen, Ken Steen, 2023, In: Porcine Health Management. 9, 41.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Development of a shared item repository for progress testing in veterinary education

    Schaper, E., van Haeften, T., Wandall, Jakob, Iivanainen, A., Penell, J., Press, C. M., Lekeux, P. & Holm, Peter, 2023, In: Frontiers in Veterinary Science. 10, 15 p., 1296514.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Differentiating Strongylus vulgaris-associated, non-strangulating intestinal infarctions from idiopathic peritonitis and acute colitis in horses

    Poulsen, L., Henriksson, F. V., Dahl, M., Honoré, M. L., Olsen, Susanne Nautrup, Leifsson, Páll S., Stærk-Østergaard, J., Jacobsen, Stine & Pihl, Tina, 2023, In: Veterinary Record. 192, 3, e2538.

    Research output: Contribution to journal › Journal article › Research › peer-review

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