Bacterial pathogenesis and treatment strategies - Mol-VET-Micro group

Research carried out in the Molecular Veterinary Microbiology (Mol-Micro-VET) group aims to find new ways to prevent and cure bacterial diseases in animals and humans, and thus to contribute to reduction in use of antimicrobials in livestock and companion animals.

Research focus

In our research, we investigate mechanisms of bacterial diseases in production and companion animals and where relevant also in humans, and we aim to understand the role of the microbiota in disease. We develop diagnostic methods, preferably those that can be used directly in veterinary practice, we explore alternatives to antibiotics (vaccines, bacteriophages, antibacterial peptides), and we study the spread of clinically relevant bacteria and antimicrobial resistance in society. Additionally, we are at the forefront of molecular bacterial taxonomy, in particular within Pasteurellaceae. 

Our tool-box is state of the art. We have a modern DNA-sequencing facility, we use sophisticated animal, microscopy and cell culture models, and we have expertise to genetically modify disease causing bacteria. We mainly work with veterinary relevant bacteria e.g. Salmonella, E. coli, staphylococci, streptococci and Pasteurella.  

Moreover, we have long collaborated (on research projects, joint PhD students) with a number of universities and veterinary institutes in developing countries and contribute to capacity building within infectious diseases in livestock production, with a strong focus on antimicrobial resistance.

We focus on bacterial pathogenesis, because if you know your enemy, then you know how to defeat it.  And we also focus on antimicrobial resistance because it is a major global health threat to humans and animals. Denmark has been a pioneer in reducing antimicrobial use in animals, but we can still improve and be an example for other countries” says research group leader John Elmerdahl Olsen.