Host-pathogen interaction in relation to salpingitis and peritonitis in poultry
Bacterial peritonitis and salpingitis are common infections found in egg-laying hens. The result of such infections are lowered animal welfare and loss of production. The main goal of our research is to investigate how these infections establish in the avian reproductive tract.
Gallibacterium anatis and Escherichia coli
Gallibacterium anatis and Escherichia coli are the main organisms investigated. Both bacteria are opportunistic pathogens and possess a high degree of genetic diversity.
A large part of the work is done by experimental infections of hens. From the infected birds, numerous samples are obtained and broad range of methods are used for analysis. Including evaluation of the lesions at different time points, counts of bacterial cells in tissue, histopathology, in situ hybridization, flow-cytometry and immunohistochemistry.
Pors SE, Olsen RH, Christensen JP. Variations in virulence of avian pathogenic Escherichia coli demonstrated by the use of a new in vivo infection model. Veterinary Microbiology 2014 Jun 4;170(3-4):368-74.