Alaskan Malamute

Alaskan Malamute

Photo: Karsten Bidstrup

Polyneuropathy (PN) – is caused by degeneration of peripheral nerves. This degeneration causes a progressive deterioration of muscles.

In Alaskan Malamute it is a specific mutation in the NDRG1 gene that causes the disease.

The mutation is found in research described in the article:

Bruun, C.S.; Jäderlund, K.H.; Berendt, M.; Jensen, K.B.; Spodsberg, E.H.; Gredal, H.; Shelton, G.D.; Mickelson, J.R:; Minor, K.M.; Lohi, H.; Bjerkås, I.; Stigen, Ø.; Espenes, A.; Rohdin, C.; Edlund, R.; Ohlsson, J.; Cizinauskas, S.; Leifsson, P.S:; Drögemüller, C.; Moe, L.; Cirera, S. and Fredholm, M. (2013): A Gly98Val mutation in the N-Myc Downstream Regulated Gene 1 (NDRG1) in Alaskan Malamutes with Polyneuropathy. PLoS One 8(2): e54547. doi: 10.1371

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Payment for DNA test for polyneuropathy in Alaskan Malamute dogs. Below you can choose the number of tests you require. Notice that discount is provided when 10 or more tests are required and in connection with testing of whole litters.
When the payment is registered the laboratory will initiate the test. The test result will be send by e-mail according to the address provided on the test-form. 

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