Expression of nitric oxide synthases and effects of L-arginine and L-NMMA on nitric oxide production and fluid transport in collagenous colitis
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Luminal nitric oxide (NO) is greatly increased in the colon of patients with collagenous and ulcerative colitis. To define the source and consequence of enhanced NO production we have studied expression of NO synthase (NOS) isoforms and nitrotyrosine in mucosal biopsies from these patients. In addition, effects on colonic fluid transfer caused by manipulating the substrate of NOS were studied in patients with collagenous colitis.
Originalsprog | Engelsk |
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Tidsskrift | Gut |
Vol/bind | 49 |
Udgave nummer | 3 |
Sider (fra-til) | 387-94 |
Antal sider | 8 |
ISSN | 0017-5749 |
Status | Udgivet - 2001 |
ID: 35922714