Pernille Tveden-Nyborg

Pernille Tveden-Nyborg

Associate Professor

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    ORCID: 0000-0002-5574-5742

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    1. Published

      Hepatic Stellate Cell Activation and Inactivation in NASH-Fibrosis—Roles as Putative Treatment Targets?

      Zisser, Alexandra, Ipsen, David Højland & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 4, 365.

      Research output: Contribution to journal › Review › Research › peer-review

    2. Published

      Gender balance in the editorial room: BCPT as model journal?

      Wellendorph, Petrine & Tveden-Nyborg, Pernille, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 6, p. 767-769

      Research output: Contribution to journal › Editorial › Research › peer-review

    3. Published

      A cafeteria diet alters the decision making strategy and metabolic markers in Sprague-Dawley male rats

      Virtuoso, Alessandro, Forkman, Björn, Sarruf, D. A., Tveden-Nyborg, Pernille & Sørensen, Dorte Bratbo, 2018, In: Applied Animal Behaviour Science. 199, p. 35-44 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      A long‐term energy‐rich diet increases prefrontal bdnf in sprague‐dawley rats

      Virtuoso, Alessandro, Tveden-Nyborg, Pernille, Schou‐pedersen, A. M. V., Lykkesfeldt, Jens, Müller, H. K., Elfving, B. & Sørensen, Dorte Bratbo, 2022, In: Nutrients. 14, 1, 126.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Does vitamin C deficiency result in impaired brain development in infants?

      Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2009, In: Redox Report. 14, 1, p. 2-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Analysis of the expression of putatively imprinted genes in bovine peri-implantation embryos

      Tveden-Nyborg, Pernille, Alexopoulos, N. I., Cooney, M. A., French, A. J., Tecirlioglu, R. T., Holland, M. K., Thomsen, Preben Dybdahl & D'Cruz, N. T., 2008, In: Theriogenology. 70, 7, p. 1119-1128 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Morphological characterization of pre- and peri-implantation in vitro cultured, somatic cell nuclear transfer and in vivo derived ovine embryos: research

      Tveden-Nyborg, Pernille, Peura, T. T., Hartwich, K. M., Walker, S. K. & Maddox-Hyttel, P., 2005, In: Reproduction. 130, 5, p. 681-694 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Developmental delay of pre-implantation ovine in vitro cultured and somatic cell nuclear transfer embryos

      Tveden-Nyborg, Pernille, Peura, T., Hartwich, K. & Maddox-Hyttel, P., 2005. 1 p.

      Research output: Contribution to conference › Paper › Research

    9. Published

      Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs

      Tveden-Nyborg, Pernille, Jensen, Louise Kruse, Raida, Z., Villumsen, C. K., Larsen, J. O. & Lykkesfeldt, Jens, 2009, In: American Journal of Clinical Nutrition. 90, 3, p. 540-546 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Pre- and peri-implantation development in ruminants: some morphological and epigenetic aspects

      Tveden-Nyborg, Pernille, 2006, Frederiksberg: Samfundslitteratur. 47 p.

      Research output: Book/Report › Ph.D. thesis › Research

    11. Published

      Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies

      Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    12. Published

      A Role of Vitamin C in the Young Brain: Effects of deficiency in a model of human hypovitaminosis C

      Tveden-Nyborg, Pernille, 2022, University of Copenhagen. 82 p.

      Research output: Book/Report › Doctoral thesis › Research

    13. Published

      BCPT policy for experimental and clinical studies

      Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 4-8

      Research output: Contribution to journal › Review › Research › peer-review

    14. Published

      Vitaminer til hjernen

      Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Aktuel Naturvidenskab. 2016, 4, p. 8-11 4 p.

      Research output: Contribution to journal › Journal article › Research

    15. Published

      BCPT 2023 policy for experimental and clinical studies

      Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 391-396

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Vitamin c deficiency in the young brain—findings from experimental animal models

      Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 5, 1685.

      Research output: Contribution to journal › Review › Research › peer-review

    17. Published

      Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies

      Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs

      Tveden-Nyborg, Pernille, Vogt, L., Schjoldager, J. G., Jeannet, N., Andersen, S. H., Paidi, M. D., Christen, S. & Lykkesfeldt, Jens, 2012, In: P L o S One. 7, 10, 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs

      Tveden-Nyborg, Pernille, Andersen, S. H., Miyashita, N., Moos, T., Poulsen, Henrik Enghusen & Lykkesfeldt, Jens, 2012, In: Basic & Clinical Pharmacology & Toxicology Online. 110, 6, p. 524-529 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs

      Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Chronic dyslipidemia induces fatty liver disease in Guinea pigs

      Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    22. Published

      In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain

      Søgaard, D., Lindblad, M. M., Paidi, M. D., Andersen, S. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrition Research. 34, 7, p. 639-645 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Vitamin C deficiency reduces muscarinic receptor coronary artery vasoconstriction and plasma tetrahydrobiopterin concentration in guinea pigs

      Skovsted, Gry Freja, Tveden-Nyborg, Pernille, Lindblad, M. M., Hansen, S. N. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 7, 14 p., 691.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Expression of endothelin type B receptors in uterine artery smooth muscle cells from pregnant Guinea pigs

      Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2019, In: Placenta. 77, p. 8-15 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet

      Skovsted, Gry Freja, Skat-Rørdam, Josephine, Frøkiær, A. P., Jensen, Henrik Elvang, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2022, In: Antioxidants. 11, 11, 2226.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Holder C-vitamin dine blodkar sunde?

      Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2018

      Research output: Other contribution › Net publication - Internet publication › Communication

    27. Published

      Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis

      Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Modelling nonalcoholic steatohepatitis in vivo—a close transcriptomic similarity supports the guinea pig disease model

      Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Sep 2021, In: Biomedicines. 9, 9, 1198.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model

      Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 9, 18 p., 1198.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig

      Skat-Rørdam, Josephine, Pedersen, Kamilla, Skovsted, Gry Freja, Gregersen, I., Vangsgaard, S., Ipsen, David Højland, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Antioxidants. 11, 1, 69.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease

      Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537

      Research output: Contribution to journal › Review › Research › peer-review

    32. Published

      Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain

      Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs: [Plus] erratum

      Schjoldager, J. G., Paidi, M. D., Lindblad, M. M., Birck, M. M., Kjærgaard, A. B., Dantzer, V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2015, In: European Journal of Nutrition. 54, 4, p. 667-676 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs

      Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Dietary Long-Chain Fatty Acids Accelerate Metabolic Dysfunction in Guinea Pigs with Non-Alcoholic Steatohepatitis

      Pedersen, Kamilla, Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2023, In: Nutrients. 15, 2445.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression

      Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

      Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

      Olsen, H. G., Kjeldgaard-Hansen, M., Tveden-Nyborg, Pernille, Birck, M. M., Hammelev, Karsten Pharao, Vegge, A., Aalbæk, Bent, Leifsson, Páll S., Jensen, Henrik Elvang, Iburg, T., Heegaard, P. M. H. & Nielsen, O. L., 2016, In: BMC Research Notes. 9, p. 1-10 10 p., 99.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Nociception after castration of juvenile pigs determined by quantitative estimation of C-fos-expressing neurones in spinal dorsal horn

      Tveden-Nyborg, Pernille, Sørig, A., Lykkegaard, K. & Svendsen, O., 2000. 1 p.

      Research output: Contribution to conference › Paper › Research

    40. Published

      Nociception efter kastraktion af juvenile grise målt ved kvantitativ bestemmelse af C-fos udtrykkende neuroner i rygmarvens dorsalhornnoci: Nociception after castration of juvenile pigs determined by quantitative estimation of C-fos-expressing neurones in spinal dorsal horn

      Tveden-Nyborg, Pernille, Sørig, A., Lykkegaard, K. & Svendsen, O., 2000, In: Dansk Veterinærtidsskrift. 83, 9, p. 16-17 2 p.

      Research output: Contribution to journal › Journal article › Research

    41. Published

      Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo

      Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Morphological assessment of preimplantation embryo quality in cattle

      Maddox-Hyttel, P., Gjørret, J. O., Vajta, G., Alexopoulos, N. I., Lewis, I., Trounson, A., Viuff, D., Laurincik, J., Müller, M., Tveden-Nyborg, Pernille & Thomsen, Preben Dybdahl, 2003, In: Reproduction. Supplement. 61, p. 103-116 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Immunohistochemical and ultrastructural characterization of the initial post-hatching development of bovine embryos

      Maddox-Hyttel, P., Alexopoulos, N. I., Vajta, G., Lewis, I., Rogers, P., Cann, L., Callesen, H., Tveden-Nyborg, Pernille & Trounson, A., 2003, In: Reproduction. 125, 4, p. 607-623 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      The Pharmacokinetics of Vitamin C

      Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.

      Research output: Contribution to journal › Review › Research › peer-review

    45. E-pub ahead of print

      Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease

      Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2024, (E-pub ahead of print) In: Laboratory Animals.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Regulation of vitamin C homeostasis during deficiency

      Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation

      Klaebel, J. H., Rakipovski, G., Andersen, B., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Antioxidants. 9, 9, 808.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model

      Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs

      Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats

      Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B., Nowak, J., Viuff, B. M., Rasmussen, C. L. M., Voetmann, Louise Marie, Fels, J. J., Madsen, S. H., McGuigan, F. E., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Akesson, K. E., 2020, In: Scientific Reports. 10, 1, 13 p., 5609.

      Research output: Contribution to journal › Journal article › Research › peer-review

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