Axel Kornerup Hansen
Professor
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Impact of the gut microbiota on rodent models of human disease
Hansen, Axel Kornerup, Hansen, Camilla Hartmann Friis, Krych, Lukasz & Nielsen, Dennis Sandris, 2014, In: World Journal of Gastroenterology. 20, 47, p. 17727-17736 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Health and welfare of laboratory animals in the light of the development within genetics
Hansen, Axel Kornerup, Sørensen, Dorte Bratbo, Krohn, T. C., Buschard, K., Stub, C. & Dahl, K., 2002. 5 p.Research output: Contribution to conference › Paper › Research
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Strategies for the assessment of competence in laboratory animal science courses
Hansen, Axel Kornerup & Sørensen, Dorte Bratbo, 2014, In: Lab Animal. 43, 10, p. 359-363 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbiota, laboratory animals, and research
Hansen, Axel Kornerup & Franklin, C., 2019, In: Laboratory Animals. 53, 3, p. 229-231 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Dyreforsøg
Hansen, Axel Kornerup & Sørensen, Dorte Bratbo, 2022, Veterinær Retsmedicin. Agger, J. F. G., Houe, H. & Otten, N. D. (eds.). 1 ed. Frederiksberg, Denmark: BiofoliaResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Considering the microbiota to achieve reduction in the numbers of animals used in scientific studies
Hansen, Axel Kornerup, 2019, In: Istituto Superiore di Sanita. Annali. 55, 4, p. 405-407 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Handbook of laboratory animal bacteriology
Hansen, Axel Kornerup & Nielsen, Dennis Sandris, 2015, 2. ed. Boca Raton, USA: CRC Press. 280 p.Research output: Book/Report › Book › Research › peer-review
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Targeting gut microbiota and barrier function with prebiotics to alleviate autoimmune manifestations in NOD mice
Hansen, Camilla Hartmann Friis, Larsen, C. S., Petersson, H. O., Zachariassen, L. F., Vegge, A., Lauridsen, C., Kot, W., Krych, Lukasz, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2019, In: Diabetologia. 62, 9, p. 1689-1700Research output: Contribution to journal › Journal article › Research › peer-review
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Gluten-free diet reduces autoimmune diabetes mellitus in mice across multiple generations in a microbiota-independent manner
Hansen, Camilla Hartmann Friis, Larsen, C. S., Zachariassen, L. F., Mentzel, Caroline M. Junker, Laigaard, A., Krych, Lukasz, Nielsen, Dennis Sandris, Gobbi, Alex, Haupt-Jorgensen, M., Buschard, K. & Hansen, Axel Kornerup, 2022, In: Journal of Autoimmunity. 127, 102795.Research output: Contribution to journal › Journal article › Research › peer-review
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Maternal antibiotic exposure increases total islet number and volume in the neonatal pancreas and reduces HbA1c and insulitis in adult female non-obese diabetic mice
Hansen, Camilla Hartmann Friis, Haupt-Jorgensen, M., Buschard, K., Pakkenberg, B., Krych, Lukasz & Hansen, Axel Kornerup, 2023, In: Clinical and Translational Discovery. 3, 2, 13 p., e188.Research output: Contribution to journal › Journal article › Research › peer-review
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Mode of delivery shapes gut colonization pattern and modulates regulatory immunity in mice
Hansen, Camilla Hartmann Friis, Andersen, L. S. F., Krych, Lukasz, Metzdorff, S. B., Hasselby, Jane Preuss, Skov, Søren, Nielsen, Dennis Sandris, Buschard, K., Hansen, Lars Hestbjerg & Hansen, Axel Kornerup, 2014, In: Journal of Immunology. 193, 3, p. 1213-1222 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells
Hansen, Camilla Hartmann Friis, Holm, T. L., Krych, Lukasz, Andresen, Lars, Nielsen, Dennis Sandris, Rune, Ida, Hansen, Axel Kornerup & Skov, Søren, 2013, In: European Journal of Immunology. 43, 2, p. 447-457 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Customizing laboratory mice by modifying gut microbiota and host immunity in an early "window of opportunity".
Hansen, Camilla Hartmann Friis, Metzdorff, S. B. & Hansen, Axel Kornerup, 2013, In: Gut Microbes. 4, 3, p. 241-245 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dietary xylooligosaccharide downregulates IFN-γ and the low-grade inflammatory cytokine IL-1β systemically in mice
Hansen, Camilla Hartmann Friis, Frøkiær, Hanne, Christensen, A. G., Bergström, A., Licht, T. R., Hansen, Axel Kornerup & Metzdorff, S. B., 2013, In: Journal of Nutrition. 143, 4, p. 533-540 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse
Hansen, Camilla Hartmann Friis, Krych, Lukasz, Nielsen, Dennis Sandris, Vogensen, Finn Kvist, Hansen, Lars Hestbjerg, Sørensen, Søren Johannes, Buschard, K. & Hansen, Axel Kornerup, 2012, In: Diabetologia. 55, 8, p. 2285-2294 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Patterns of early gut colonization shape future immune responses of the host
Hansen, Camilla Hartmann Friis, Nielsen, Dennis Sandris, Kverka, M., Zakostelska, Z., Klimesova, K., Hudcovic, T., Tlaskalova-Hogenova, H. & Hansen, Axel Kornerup, 2012, In: P L o S One. 7, 3, p. e34043 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A maternal gluten-free diet reduces inflammation and diabetes incidence in the offspring of NOD mice
Hansen, Camilla Hartmann Friis, Krych, Lukasz, Buschard, K., Metzdorff, S. B., Nellemann, C. L., Hansen, Lars Hestbjerg, Nielsen, Dennis Sandris, Frøkiær, Hanne, Skov, Søren & Hansen, Axel Kornerup, 2014, In: Diabetes. 63, 8, p. 2821-2832 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A comparison of various methods of blood sampling in mice and rats: Effects on animal welfare
Sreelatha, Harikrishnan Vijayakumar, Hansen, Axel Kornerup, Abelson, Klas & Sørensen, Dorte Bratbo, 2018, In: Laboratory Animals. 52, 3, p. 253-264Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial hyperlipemia in pigs
Harslund, J. L. F., Olsen, A. K. & Hansen, Axel Kornerup, 2003, In: Scandinavian Journal of Laboratory Animal Science. 30, 4, p. 177-190 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gluten-free diet during pregnancy alleviates signs of diabetes and celiac disease in NOD mouse offspring
Haupt-Jorgensen, M., Larsen, J., Josefsen, K., Jørgensen, T. Z., Antvorskov, J. C., Hansen, Axel Kornerup & Buschard, K., 2018, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 34, 4, 10 p., e2987.Research output: Contribution to journal › Journal article › Research › peer-review
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Gluten-free diet increases beta-cell volume and improves glucose tolerance in an animal model of type 2 diabetes
Haupt-Jørgensen, M., Buschard, K., Hansen, Axel Kornerup, Josefsen, K. & Antvorskov, J. C., Oct 2016, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 32, 7, p. 675-684 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dual nuclear magnetic resonance for probing intrinsic bone structure and a potential gut–bone axis in ovariectomized rats
He, W., Jakobsen, L. M. A., Zachariassen, L. F., Hansen, Axel Kornerup, Andersen, H. J. & Bertram, H. C., 2022, In: Magnetic Resonance in Chemistry. 60, 7, p. 651-658Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model
He, W., Xie, Zhuqing, Thøgersen, R., Rasmussen, M. K., Zachariassen, L. F., Jørgensen, Niklas Rye, Nørgaard, J. V., Andersen, H. J., Nielsen, Dennis Sandris, Hansen, Axel Kornerup & Bertram, H. C., 2022, In: Molecular Nutrition and Food Research. 66, 8, 12 p., 2100883.Research output: Contribution to journal › Journal article › Research › peer-review
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Yogurt Benefits Bone Mineralization in Ovariectomized Rats with Concomitant Modulation of the Gut Microbiome
He, W., Xie, Zhuqing, Wittig, N. K., Zachariassen, L. F., Andersen, A., Andersen, H. J., Birkedal, H., Nielsen, Dennis Sandris, Hansen, Axel Kornerup & Bertram, H. C., 2022, In: Molecular Nutrition and Food Research. 66, 20, 10 p., 2200174.Research output: Contribution to journal › Journal article › Research › peer-review
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A ¤search for acceptable maximum doses for gavaging rats
Hejgaard, K. C., Thomsen, Preben Dybdahl & Hansen, Axel Kornerup, 2000, Ikke angivet. Laboratory Animals Ltd, p. 21-23 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
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Oligosaccharide equine feed supplement, Immulix, has minor impact on vaccine responses in mice
Henriksen, Ida Wang , Mejia, J. L. C., Mentzel, Caroline M. Junker, Lindenberg, F. & Hansen, Axel Kornerup, 2022, In: Scientific Reports. 12, 582.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of the piroxicam-accelerated interleukin-10 knock out mouse: - As a model of human inflammatory bowel disease.
Holgersen, Kristine, Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., Sep 2012.Research output: Contribution to conference › Poster › Research › peer-review
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High-resolution gene expression profiling using RNA sequencing in patients with inflammatory bowel disease and in mouse models of colitis
Holgersen, Kristine, Kutlu, B., Fox, B., Serikawa, K., Lord, J., Hansen, Axel Kornerup & Holm, T. L., Mar 2015, In: Journal of Crohn's and Colitis (JCC). 9, 6, p. 492-506 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Validation of Piroxicam-Accelerated Colitis in the Interleukin-10 Knock out Mouse - a Preclinical Model Mimicking Human Inflammatory Bowel Disease
Holgersen, Kristine, Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., May 2014.Research output: Contribution to conference › Poster › Research › peer-review
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Piroxicam-accelerated colitis in interleukin-10 knock out mice a “new” model of human inflammatory bowel disease
Holgersen, K., Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., 2013. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Piroxicam treatment augments bone abnormalities in interleukin-10 knockout mice
Holgersen, Kristine, Dobie, R., Farquharson, C., Van't Hof, R., Ahmed, S. F., Hansen, Axel Kornerup & Lindebo Holm, T., Feb 2015, In: Inflammatory Bowel Diseases. 21, 2, p. 257-266 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterisation of enterocolitis in the piroxicam-accelerated interleukin-10 knock out mouse: a model mimicking inflammatory bowel disease
Holgersen, Kristine, Kvist, P. H., Markholst, H., Hansen, Axel Kornerup & Holm, T. L., 2014, In: Journal of Crohn's and Colitis. 8, 2, p. 147-160 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predictive validity and immune cell involvement in the pathogenesis of piroxicam-accelerated colitis in interleukin-10 knockout mice
Holgersen, Kristine, Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., 2014, In: International Immunopharmacology. 21, 1, p. 137-147 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FELASA guidance paper for the accreditation of laboratory animal diagnostic laboratories: report of the Federation of European Laboratory Animal Science Associations (FELASA) Working Group on Accreditation of Diagnostic Laboratories
Homberger, F. R., Boot, R., Feinstein, R., Hansen, Axel Kornerup & Logt, J. V. D., 1999, In: Laboratory Animals. Journal of the Laboratory Animal Science Association. 33, 1, p. 19-38 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies
Hu, H., Kofoed, Christian, Li, M., Gonçalves, J. P. L., Hansen, J., Wolfram, M., Hansen, Axel Kornerup, Hansen, Camilla Hartmann Friis, Diness, Frederik, Schoffelen, S. & Meldal, Morten Peter, 27 Feb 2019, In: ACS Central Science. 5, 2, p. 259-269 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Refinement of animal models influenced by the intestinal microbiota
Hufeldt, M. R., Vogensen, Finn Kvist, Nielsen, Dennis Sandris, Midtvedt, T. & Hansen, Axel Kornerup, Jun 2010.Research output: Contribution to conference › Conference abstract for conference › Research
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Characterising the variation in the composition of the intestinal microbiota in mice
Hufeldt, M. R., Vogensen, Finn Kvist & Hansen, Axel Kornerup, 2010.Research output: Contribution to conference › Poster › Research
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Variation in the gut microbiota of laboratory mice is related to both genetic and environmental factors
Hufeldt, M. R., Nielsen, Dennis Sandris, Vogensen, Finn Kvist, Midtvedt, T. & Hansen, Axel Kornerup, 2010, In: Comparative Medicine. 60, 5, p. 336-342 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Family relationship of female breeders reduce the systematic inter-individual variation in the gut microbiota of inbred laboratory mice
Hufeldt, M. R., Nielsen, Dennis Sandris, Vogensen, Finn Kvist, Midtvedt, T. & Hansen, Axel Kornerup, 2010, In: Laboratory Animals. Journal of the Laboratory Animal Science Association. 44, 4, p. 283-289 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitation of regional cerebral blood flow corrected for partial volume effect using O-15 water and PET: I. theory, error analysis, and stereologic comparison
IIda, H., Law, I., Pakkenberg, B., Krarup-Hansen, A., Eberl, S., Holm, S., Hansen, Axel Kornerup, Gundersen, H. J. G., Thomsen, C., Svarer, C., Ring, P., Friberg, L. & Paulson, O. B., 2000, In: Journal of Cerebral Blood Flow and Metabolism. 20, p. 1237-1251 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic nephropathy in guinea pigs, pathological classification and correlation with changes in haematological and urine parameters
Iburg, T., Jehg, M. L., Hansen, Axel Kornerup & Rueløkke, Mette Lybek, 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Administration of bovine milk oligosaccharide to weaning gnotobiotic mice inoculated with a simplified infant type microbiota
Jakobsen, L. M. A., Sundekilde, U. K., Andersen, H. J., Kot, Witold, Mejia, J. L. C., Nielsen, Dennis Sandris, Hansen, Axel Kornerup & Bertram, H. C., 2021, In: Microorganisms. 9, 5, 1003.Research output: Contribution to journal › Journal article › Research › peer-review
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Vurdering af sundhed og velfærd hos genmodificerede forsøgsdyr
Jegstrup, I. M., Dahl, K., Stub, C., Sørensen, Dorte Bratbo, Krohn, T. C., Hansen, Axel Kornerup, Ritskes-Hoitinga, M., Thon, R., Madsen, K. H., Sandøe, Peter & Tveit, Geir (ed.), 2003, In: Vedr. bioteknologi og offentligheden. p. 67-74 8 p.Research output: Contribution to journal › Journal article › Research
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A volumetric screening procedure for the Göttingen minipig brain
Jelsing, J., Olsen, A. K., Cumming, P., Gjedde, A., Hansen, Axel Kornerup, Arnfred, S. & Hemmingsen, R., 2005, In: Experimental Brain Research. 162, p. 428-435 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A possible link between food and mood: dietary impact on gut microbiota and behavior in BALB/c mice
Jørgensen, B. M. P., Hansen, J. T., Krych, Lukasz, Larsen, C. S., Klein, A. B., Nielsen, Dennis Sandris, Josefsen, K., Hansen, Axel Kornerup & Sørensen, Dorte Bratbo, 2014, In: PLOS ONE. 9, 8, p. e103398 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigating the long-term effect of subchronic phencyclidine-treatment on novel object recognition and the association between the gut microbiota and behavior in the animal model of schizophrenia
Jørgensen, B. M. P., Krych, Lukasz, Brønnum Pedersen, T., Plath, N., Redrobe, J. P., Hansen, Axel Kornerup, Nielsen, Dennis Sandris, Spang Pedersen, C., Larsen, C. S. & Sørensen, Dorte Bratbo, 2015, In: Physiology & Behavior. 141, p. 32-39 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dietary magnesium deficiency affects gut microbiota and anxiety-like behaviour in C57BL/6N mice
Jørgensen, B. M. P., Winther, G., Kihl, Pernille, Nielsen, Dennis Sandris, Wegener, G., Hansen, Axel Kornerup & Sørensen, Dorte Bratbo, 2015, In: Acta Neuropsychiatrica (Print). 27, 5, p. 307-311 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4237328
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A possible link between food and mood: dietary impact on gut microbiota and behavior in BALB/c mice
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2-heptyl-formononetin increases cholesterol and induces hepatic steatosis in mice
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Laparoscopic Roux-en-Y gastric bypass in super obese Göttingen minipigs
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