Ernst Stefan Seemann
Associate Professor
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SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
Damas, N. D., Marcatti, M., Côme, Christophe Roger Michel, Christensen, L., Nielsen, M. M., Baumgartner, R., Gylling, H. M., Maglieri, G., Friis, Carsten, Seemann, Ernst Stefan, Rapin, N., Thézenas, S., Vang, S., Ørntoft, T., Andersen, C. L., Pedersen, J. S. & Lund, Anders H., 22 Dec 2016, In: Nature Communications. 7, 14 p., 13875.Research output: Contribution to journal › Journal article › Research › peer-review
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Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3
Haukedal, H., Syshøj Lorenzen, S., Westi, Emil Winther, Corsi, G., Gadekar, V. P., McQuade, A., Davtyan, H., Doncheva, Nadezhda Tsankova, Schmid, B., Chandrasekaran, Abinaya, Seemann, Ernst Stefan, Cirera, Susanna, Blurton-Jones, M., Meyer, M., Gorodkin, Jan, Aldana, Blanca & Freude, Kristine, 2023, In: Brain, Behavior, and Immunity. 113, p. 353-373Research output: Contribution to journal › Journal article › Research › peer-review
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Associating transcription factors and conserved RNA structures with gene regulation in the human brain
Hecker, N., Seemann, Ernst Stefan, Silahtaroglu, Asli, Ruzzo, W. L. & Gorodkin, Jan, 2017, In: Scientific Reports. 7, 1, 16 p., 5776.Research output: Contribution to journal › Journal article › Research › peer-review
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Bsgatlas: A unified bacillus subtilis genome and transcriptome annotation atlas with enhanced information access
Geissler, Adrian Sven, Anthon, Christian, Alkan, F., González-Tortuero, E., Poulsen, L. D., Kallehauge, T. B., Breüner, A., Seemann, Ernst Stefan, Vinther, Jeppe & Gorodkin, Jan, 2021, In: Microbial Genomics. 7, 2, 17 p., 000524.Research output: Contribution to journal › Journal article › Research › peer-review
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CRISPRi screen for enhancing heterologous alpha-amylase yield in Bacillus subtilis
Geissler, Adrian Sven, Fehler, A. O., Poulsen, L. D., Gonzalez-Tortuero, E., Kallehauge, T. B., Alkan, F., Anthon, Christian, Seemann, Ernst Stefan, Rasmussen, M. D., Breuener, A., Hjort, C., Vinther, Jeppe & Gorodkin, Jan, 2023, In: Journal of Industrial Microbiology and Biotechnology. 50, 1, 16 p., kuac028.Research output: Contribution to journal › Journal article › Research › peer-review
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CRISPRroots: On-and off-target assessment of RNA-seq data in CRISPR-Cas9 edited cells
Corsi, G. I., Gadekar, V. P., Gorodkin, Jan & Seemann, Ernst Stefan, 2022, In: Nucleic Acids Research. 50, 4, 12 p., E20.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of RNA structures in porcine EST data and related mammals
Seemann, Ernst Stefan, Gilchrist, M. J., Hofacker, I. L., Stadler, P. F. & Gorodkin, Jan, 2007, In: BMC Genomics. 8, 316, 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of the entorhinal cortex occurs via parallel lamination during neurogenesis
Liu, Y., Bergmann, T., Mori, Yuki, Peralvo Vidal, Juan Miguel, Pihl, M., Vasistha, Navneet A, Thomsen, Preben Dybdahl, Seemann, Ernst Stefan, Gorodkin, Jan, Hyttel, P., Khodosevich, Konstantin, Witter, M. P. & Hall, Vanessa Jane, 2021, In: Frontiers in Neuroanatomy. 15, 19 p., 663667.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells: [Plus] Corrigendum
Hölzer, M., Krähling, V., Amman, F., Barth, E., Bernhart, S. H., Carmelo, V. A. O., Collatz, M., Doose, G., Eggenhofer, F., Ewald, J., Fallmann, J., Feldhahn, L. M., Fricke, M., Gebauer, J., Gruber, A. J., Hufsky, F., Indrischek, H., Kanton, S., Linde, J., Mostajo, N. & 19 others, , 7 Oct 2016, In: Scientific Reports. 6, 16 p., 34589.Research output: Contribution to journal › Journal article › Research › peer-review
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Does rapid sequence divergence preclude RNA structure conservation in vertebrates?
Seemann, Ernst Stefan, Mirza, A. H., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Workman, C. T., Pociot, Flemming, Tommerup, Niels, Gorodkin, Jan & Ruzzo, W. L., 2022, In: Nucleic Acids Research. 50, 5, p. 2452-2463 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DotAligner: Identification and clustering of RNA structure motifs
Smith, M. A., Seemann, Ernst Stefan, Quek, X. C. & Mattick, J. S., Dec 2017, In: Genome Biology. 18, 1, 12 p., 244.Research output: Contribution to journal › Journal article › Research › peer-review
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Emerging tools for RNA structure analysis in polymorphic data
Radhakrishnan, S., Seemann, Ernst Stefan & Gorodkin, Jan, 2015, In: Biozoom. 2, p. 10-13 4 p.Research output: Contribution to journal › Journal article › Communication
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Flagella disruption in Bacillus subtilis increases amylase production yield
Fehler, A. O., Kallehauge, T. B., Geissler, Adrian Sven, González-Tortuero, E., Seemann, Ernst Stefan, Gorodkin, Jan & Vinther, Jeppe, 2022, In: Microbial Cell Factories. 21, 11 p., 131.Research output: Contribution to journal › Journal article › Research › peer-review
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Full-length RNA structure prediction of the HIV-1 genome reveals a conserved core domain
Sükösd, Z., Andersen, E. S., Seemann, Ernst Stefan, Jensen, M. K., Hansen, M., Gorodkin, Jan & Kjems, J., 2 Dec 2015, In: Nucleic Acids Research. 43, 21, p. 10168-79 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hierarchical folding of multiple sequence alignments for the prediction of structures and RNA-RNA interactions
Seemann, Ernst Stefan, Richter, A. S., Gorodkin, Jan & Backofen, R., 2010, In: Algorithms for Molecular Biology. 5, 22, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification and characterization of novel conserved RNA structures in Drosophila
Kirsch, Rebecca, Seemann, Ernst Stefan, Ruzzo, W. L., Cohen, S. M., Stadler, P. F. & Gorodkin, Jan, 2018, In: BMC Genomics. 19, 20 p., 899.Research output: Contribution to journal › Journal article › Research › peer-review
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Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model
Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 9, 18 p., 1198.Research output: Contribution to journal › Journal article › Research › peer-review
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Modelling nonalcoholic steatohepatitis in vivo—a close transcriptomic similarity supports the guinea pig disease model
Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Sep 2021, In: Biomedicines. 9, 9, 1198.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple Sequence Alignments Enhance Boundary Definition of RNA Structures
Sabarinathan, R., Anthon, Christian, Gorodkin, Jan & Seemann, Ernst Stefan, 4 Dec 2018, In: Genes. 9, 12, 17 p., 604.Research output: Contribution to journal › Journal article › Research › peer-review
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Optimizing RNA structures by sequence extensions using RNAcop
Hecker, N., Christensen-Dalsgaard, M., Seemann, Ernst Stefan, Havgaard, Jakob Hull, Stadler, P. F., Hofacker, I. L., Nielsen, Henrik & Gorodkin, Jan, 2015, In: Nucleic Acids Research. 43, 17, p. 8135-8145 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PETcofold: predicting conserved interactions and structures of two multiple alignments of RNA sequences
Seemann, Ernst Stefan, Richter, A. S., Gesell, T., Backofen, R. & Gorodkin, Jan, 2011, In: Bioinformatics. 27, 2, p. 211-219 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prediction of structured non-coding RNAs, RNA-RNA interactions and their (co)-expression in the brain
Seemann, Ernst Stefan, 2010, Department of Basic Animal and Veterinary Sciences, University of Copenhagen. 195 p.Research output: Book/Report › Ph.D. thesis › Research
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Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming
Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, , 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.Research output: Contribution to journal › Journal article › Research › peer-review
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Production of stellate cells from induced pluripotent stem cells to study Alzheimer's disease pathology
Mogus, L., Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
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Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi
Cavazza, A., Hendel, A., Bak, R. O., Rio, P., Güell, M., Lainšček, D., Arechavala-Gomeza, V., Peng, L., Hapil, F. Z., Harvey, J., Ortega, F. G., Gonzalez-Martinez, C., Lederer, C. W., Mikkelsen, K., Gasiunas, G., Kalter, N., Gonçalves, M. A. F. V., Petersen, J., Garanto, A., Montoliu, L. & 20 others, , 2023, In: Molecular Therapy Nucleic Acids. 34, 14 p., 102066.Research output: Contribution to journal › Review › Research › peer-review
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Proteomic profiling of the thrombin-activated canine platelet secretome (CAPS)
Cremer, Signe Emilie, Catalfamo, J. L., Goggs, R., Seemann, Ernst Stefan, Kristensen, Annemarie T. & Brooks, M. B., 2019, In: PLoS ONE. 14, 11, e0224891.Research output: Contribution to journal › Journal article › Research › peer-review
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Quality Assessment of Domesticated Animal Genome Assemblies
Seemann, Ernst Stefan, Anthon, Christian, Palasca, Oana & Gorodkin, Jan, 2015, In: Bioinformatics and Biology Insights. 9, Suppl 4, p. 49-58 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RILogo: visualising RNA-RNA interactions
Menzel, K. P., Seemann, Ernst Stefan & Gorodkin, Jan, 2012, In: Bioinformatics. 28, 19, p. 2523-2526 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RNA-Seq Study on the Longissimus thoracis Muscle of Italian Large White Pigs Fed Extruded Linseed with or without Antioxidants and Polyphenols
Vegni, J., Sun, Y., Seemann, Ernst Stefan, Zappaterra, M., Davoli, R., Dall’Olio, S., Gorodkin, Jan & Zambonelli, P., 2023, In: Animals. 13, 7, 1187.Research output: Contribution to journal › Journal article › Research › peer-review
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RNAcentral: a hub of information for non-coding RNA sequences
The RNAcentral Constortium , T., Gorodkin, Jan & Seemann, Ernst Stefan, 2019, In: Nucleic Acids Research. 47, D1, p. D221–D229Research output: Contribution to journal › Journal article › Research › peer-review
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RNAcentral 2021: Secondary structure integration, improved sequence search and new member databases
Sweeney, B. A., Petrov, A. I., Ribas, C. E., Finn, R. D., Bateman, A., Szymanski, M., Karlowski, W. M., Seemann, S. E., Gorodkin, J., Cannone, J. J., Gutell, R. R., Kay, S., Marygold, S., Dos Santos, G., Frankish, A., Mudge, J. M., Barshir, R., Fishilevich, S., Chan, P. P., Lowe, T. M. & 26 others, , 2021, In: Nucleic Acids Research. 49, D1, p. D212-D220Research output: Contribution to journal › Journal article › Research › peer-review
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RNAscClust: Clustering RNA sequences using structure conservation and graph based motifs
Miladi, M., Junge, A., Costa, F., Seemann, Ernst Stefan, Havgaard, Jakob Hull, Gorodkin, Jan & Backofen, R., 2017, In: Bioinformatics. 33, 14, p. 2089-2096 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RNAsnp: efficient detection of local RNA secondary structure changes induced by SNPs: efficient detection of local RNA secondary structure changes induced by SNPs
Radhakrishnan, S., Tafer, H., Seemann, Ernst Stefan, Hofacker, I. L., Stadler, P. F. & Gorodkin, Jan, 2013, In: Human Mutation. 34, 4, p. 546-556 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sandwich cortial lamination and single-cell analysis decodes the developing spatial processing system
Liu, Y., Bergmann, T. B., Lee, J., Pfisterer, U. G., Handfield, L-F., Mori, Y., Asenjo Martinez, A., Lisa Vargas, I., Seemann, E. S., Lee, J. T. H., Patikis, N., Peralvo Vidal, J. M., Pihl, M., Kornum, B. R., Thomsen, P. D., Hyttel, P., Witter, M., Khodosevich, K., Gorodkin, J., Hemberg, M. & 2 others, , 2019. 45 p.Research output: Contribution to conference › Paper › Communication
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Sequence and expression analysis of gaps in human chromosome 20
Minocherhomji, S., Seemann, Ernst Stefan, Mang, Y., Elschich, Z., Bak, M., Hansen, C., Papadopoulos, N., Josefsen, K., Nielsen, Henrik, Gorodkin, Jan, Tommerup, Niels & Silahtaroglu, Asli, Aug 2012, In: Nucleic Acids Research. 40, 14, p. 6660-6672 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single cell mapping the evolution of the spatial processing centre within the brain
Ralbovszki, Dorottya Maria, Bertelsen, Mads Frost, Buchmann, Kurt, Mori, Yuki, Gorodkin, Jan, Hemberg, M., Seemann, Ernst Stefan, Khodosevich, Konstantin & Hall, Vanessa Jane, 1 May 2022.Research output: Contribution to conference › Poster › Communication
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Structured RNAs and synteny regions in the pig genome
Anthon, Christian, Tafer, H., Havgaard, Jakob Hull, Thomsen, B., Hedegaard, J., Seemann, Ernst Stefan, Pundhir, Sachin, Kehr, S., Bartschat, S., Nielsen, M., Nielsen, R. O., Fredholm, Merete, Stadler, P. F. & Gorodkin, Jan, 2014, In: BMC Genomics. 15, 27 p., 459.Research output: Contribution to journal › Journal article › Research › peer-review
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The Bacillaceae-1 RNA motif comprises two distinct classes
González-Tortuero, E., Anthon, Christian, Havgaard, Jakob Hull, Geissler, Adrian Sven, Breüner, A., Hjort, C., Gorodkin, Jan & Seemann, Ernst Stefan, 2022, In: Gene. 841, 146756.Research output: Contribution to journal › Journal article › Research › peer-review
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The PETfold and PETcofold web servers for intra- and intermolecular structures of multiple RNA sequences
Seemann, Ernst Stefan, Menzel, K. P., Backofen, R. & Gorodkin, Jan, 2011, In: Nucleic Acids Research. 39, Suppl. 2, p. W107-W111 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The RNAsnp web server: predicting SNP effects on local RNA secondary structure
Radhakrishnan, S., Tafer, H., Seemann, Ernst Stefan, Hofacker, I. L., Stadler, P. F. & Gorodkin, Jan, 2013, In: Nucleic Acids Research. 41, p. W475-W479 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The canine activated platelet secretome (CAPS): A translational model of thrombin-evoked platelet activation response
Cremer, Signe Emilie, Catalfamo, J. L., Goggs, R., Seemann, Ernst Stefan, Kristensen, Annemarie T., Szklanna, P. B., Maguire, P. B. & Brooks, M. B., 2021, In: Research and Practice in Thrombosis and Haemostasis. 5, 1, p. 55-68Research output: Contribution to journal › Journal article › Research › peer-review
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The developing Entorhinal Cortex – a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
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The developing Entorhinal cortex - a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 25 Nov 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
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The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.
Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
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The identification and functional annotation of RNA structures conserved in vertebrates
Seemann, Ernst Stefan, Mirza, A. H., Hansen, C., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Torarinsson, E., Yao, Z., Workman, C. T., Pociot, Flemming, Nielsen, Henrik, Tommerup, Niels, Ruzzo, W. L. & Gorodkin, Jan, 2017, In: Genome Research. 27, p. 1371-1383 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of PrsA over-expression on the Bacillus subtilis transcriptome during fed-batch fermentation of alpha-amylase production
Geissler, Adrian Sven, Poulsen, L. D., Doncheva, Nadezhda Tsankova, Anthon, Christian, Seemann, Ernst Stefan, González-Tortuero, E., Breüner, A., Jensen, Lars Juhl, Hjort, C., Vinther, Jeppe & Gorodkin, Jan, 2022, In: Frontiers in Microbiology. 13, 17 p., 909493.Research output: Contribution to journal › Journal article › Research › peer-review
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The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression
Corsi, G. I., Gadekar, V. P., Haukedal, H., Doncheva, Nadezhda Tsankova, Anthon, Christian, Ambardar, S., Palakodeti, D., Hyttel, P., Freude, Kristine, Seemann, Ernst Stefan & Gorodkin, Jan, 2023, In: Neurobiology of Disease. 178, 17 p., 105980.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic landscape of lncRNAs in inflammatory bowel disease
Mirza, A. H., Bang-Berthelsen, C. H., Seemann, Ernst Stefan, Pan, X., Frederiksen, K. S., Vilien, M., Gorodkin, Jan & Pociot, Flemming, 2015, In: Genome Medicine. 7, 22 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcripts with in silico predicted RNA structure are enriched everywhere in the mouse brain
Seemann, Ernst Stefan, Sunkin, S. M., Hawrylycz, M. J., Ruzzo, W. L. & Gorodkin, Jan, 2012, In: BMC Genomics. 13, 1, p. 214-227 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.
Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
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Uncovering the anatomical and molecular landscape of the starting point of Alzheimer’s disease in the brain
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
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Unifying evolutionary and thermodynamic information for RNA folding of multiple alignments
Seemann, Ernst Stefan, Gorodkin, Jan & Backofen, R., 2008, In: Nucleic Acids Research. 36, 20, p. 6355-6362 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4223622
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Detection of RNA structures in porcine EST data and related mammals
Research output: Contribution to journal › Journal article › Research › peer-review
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879
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Structured RNAs and synteny regions in the pig genome
Research output: Contribution to journal › Journal article › Research › peer-review
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Unifying evolutionary and thermodynamic information for RNA folding of multiple alignments
Research output: Contribution to journal › Journal article › Research › peer-review
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