Pernille Tveden-Nyborg

Pernille Tveden-Nyborg

Associate Professor

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    ORCID: 0000-0002-5574-5742

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    1. Published

      Developmental disparity between in vitro-produced and somatic cell nuclear transfer bovine days 14 and 21 embryos: implications for embryonic loss

      Alexopoulos, N. I., Maddox-Hyttel, P., Tveden-Nyborg, Pernille, Cruz, N. T. D., Tecirlioglu, T. R., Cooney, M. A., Schauser, K. H., Holland, M. K. & French, A. J., 2008, In: Reproduction. 136, 4, p. 433-445 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Vitamin C and its role in brain development and cognition

      Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2012, Nutrition and mental performance: a develomental perspective. Riby, L., Smith, M. & Foster, J. (eds.). Palgrave Macmillan, p. 29-52 24 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    3. Published

      Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs

      Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2015, In: British Journal of Nutrition. 113, 10, p. 1539-1549 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Non-terminal blood sampling techniques in Guinea pigs

      Birck, M. M., Tveden-Nyborg, Pernille, Lindblad, M. M. & Lykkesfeldt, Jens, 2014, In: Journal of Visualized Experiments. 92, e51982.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Decreased expression of the GLP-1 receptor after segmental artery injury in mice

      Bjørnholm, K. D., Povlsen, G. K., Ougaard, M. E., Pyke, C., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Skovsted, Gry Freja, 2021, In: The Journal of endocrinology. 248, 3, p. 289-301 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis, and affects genes involved in vascular remodelling and inflammation

      Bjørnholm, K. D., Skovsted, Gry Freja, Mitgaard-Thomsen, A., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Povlsen, G. K., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 103-114

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders

      Frederiksen, Henriette Reventlow S, Doehn, U., Tveden-Nyborg, Pernille & Freude, Kristine, 2021, In: Frontiers in Genome Editing. 2, 623717.

      Research output: Contribution to journal › Review › Research › peer-review

    8. Published

      Novel traceable CRISPR-Cas9 engineered human embryonic stem cell line (E1C3 + hSEAP + 2xKO + pCD47), has potential to evade immune detection in pigs

      Frederiksen, Henriette Reventlow S, Skov, Søren, Tveden-Nyborg, Pernille, Freude, Kristine & Doehn, U., 7 May 2024, In: Stem Cell Research.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Vitamin C - ascorbic acid

      Frikke-Schmidt, H., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens, Drake, V. J. & Frei, B., 28 Feb 2011, Vitamins in the Prevention of Human Diseases. Walter de Gruyter GmbH and Co. KG, p. 323-362 40 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    10. Published

      High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs

      Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille, Birck, M. M. & Lykkesfeldt, Jens, 2011, In: British Journal of Nutrition. 105, 1, p. 54-61 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Vitamin C in human nutrition

      Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2011, Vitamins in the prevention of human diseases. Herrmann, W. & Obeid, R. (eds.). De Gruyter, p. 323-362 40 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    12. Published

      L-dehydroascorbic acid can substitute L-ascorbic acid as dietary vitamin C source in guinea pigs

      Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Early life vitamin C deficiency does not alter morphology of hippocampal CA1 pyramidal neurons or markers of synaptic plasticity in a Guinea pig model

      Hansen, S. N., Jørgensen, J. M. B., Nyengaard, J. R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Nutrients. 10, 6, 749.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Maternal vitamin C deficiency does not reduce hippocampal volume and beta-tubulin III intensity in prenatal Guinea pigs

      Hansen, S. N., Schjoldager, J. G., Paidi, M. D., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Jul 2016, In: Nutrition Research. 36, 7, p. 696-702

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation

      Hansen, S. N., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Antioxidants. 7, 7, p. 11 82.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Does vitamin C deficiency affect cognitive development and function?

      Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Long term Westernized diet leads to region-specific changes in brain signaling mechanisms

      Hansen, S. N., Ipsen, David Højland, Schou-Pedersen, A. M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Neuroscience Letters. 676, p. 85-91 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs

      Ipsen, David Højland, Agerskov, R. H., Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Scientific Reports. 11, 2955.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis

      Ipsen, David Højland, Rolin, B., Rakipovski, G., Skovsted, Gry Freja, Madsen, A., Kolstrup, S., Schou-Pedersen, A. M., Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 704-713

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Animal Models of Fibrosis in Nonalcoholic Steatohepatitis: Do They Reflect Human Disease?

      Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Advances in Nutrition. 11, 6, p. 1696–1711

      Research output: Contribution to journal › Review › Research › peer-review

    21. Published

      Dyslipidemia: Obese or Not Obese-That Is Not the Question

      Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Dec 2016, In: Current Obesity Reports. 5, 4, p. 405-412

      Research output: Contribution to journal › Review › Research › peer-review

    22. Published

      Normal Weight Dyslipidemia: Is It All About the Liver?

      Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Mar 2016, In: Obesity. 24, 3, p. 556-567 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    23. Published

      Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

      Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Cellular and Molecular Life Sciences. 75, 18, p. 3313-3327 15 p.

      Research output: Contribution to journal › Review › Research › peer-review

    24. Published

      Når leveren bliver for fed

      Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Aktuel Naturvidenskab. 2019, 3, p. 28-31

      Research output: Contribution to journal › Journal article › Communication

    25. Published

      Does vitamin C deficiency promote fatty liver disease development?

      Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.

      Research output: Contribution to journal › Review › Research › peer-review

    26. Published

      High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs

      Ipsen, David Højland, Tveden-Nyborg, Pernille, Rolin, B., Rakipovski, G., Beck, M., Mortensen, L. W., Færk, L., Heegaard, P. M. H., Møller, Peter & Lykkesfeldt, Jens, 2016, In: Nutrition & Metabolism. 13, p. 51

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis

      Ipsen, David Højland, Skat-Rørdam, Josephine, Svenningsen, M., Andersen, Mia Trein, Latta, M., Buelund, Lene Elisabeth, Lintrup, K., Skaarup, R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 4, p. 583-593

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model

      Ipsen, David Højland, Skat-Rørdam, Josephine, Tsamouri, M. M., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Molecular Genetics and Genomics. 294, 3, p. 649–661

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Extracellular vesicles as drivers of non-alcoholic fatty liver disease: Small particles with big impact

      Ipsen, David Højland & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 1, p. 1-13 13 p., 93.

      Research output: Contribution to journal › Review › Research › peer-review

    30. Published

      Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models

      Jensen, Victoria Svop, Tveden-Nyborg, Pernille, Zacho-Rasmussen, C., Quaade, Michelle Lauge, Ipsen, David Højland, Hvid, H., Fledelius, C., Wulff, E. M. & Lykkesfeldt, Jens, 2020, In: Journal of Pharmacological and Toxicological Methods. 101, 9 p., 106651.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats

      Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B., Nowak, J., Viuff, B. M., Rasmussen, C. L. M., Voetmann, Louise Marie, Fels, J. J., Madsen, S. H., McGuigan, F. E., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Akesson, K. E., 2020, In: Scientific Reports. 10, 1, 13 p., 5609.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation

      Klaebel, J. H., Rakipovski, G., Andersen, B., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Antioxidants. 9, 9, 808.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model

      Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs

      Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Regulation of vitamin C homeostasis during deficiency

      Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. E-pub ahead of print

      Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease

      Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2024, (E-pub ahead of print) In: Laboratory Animals.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      The Pharmacokinetics of Vitamin C

      Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.

      Research output: Contribution to journal › Review › Research › peer-review

    38. Published

      Morphological assessment of preimplantation embryo quality in cattle

      Maddox-Hyttel, P., Gjørret, J. O., Vajta, G., Alexopoulos, N. I., Lewis, I., Trounson, A., Viuff, D., Laurincik, J., Müller, M., Tveden-Nyborg, Pernille & Thomsen, Preben Dybdahl, 2003, In: Reproduction. Supplement. 61, p. 103-116 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Immunohistochemical and ultrastructural characterization of the initial post-hatching development of bovine embryos

      Maddox-Hyttel, P., Alexopoulos, N. I., Vajta, G., Lewis, I., Rogers, P., Cann, L., Callesen, H., Tveden-Nyborg, Pernille & Trounson, A., 2003, In: Reproduction. 125, 4, p. 607-623 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo

      Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Nociception after castration of juvenile pigs determined by quantitative estimation of C-fos-expressing neurones in spinal dorsal horn

      Tveden-Nyborg, Pernille, Sørig, A., Lykkegaard, K. & Svendsen, O., 2000. 1 p.

      Research output: Contribution to conference › Paper › Research

    42. Published

      Nociception efter kastraktion af juvenile grise målt ved kvantitativ bestemmelse af C-fos udtrykkende neuroner i rygmarvens dorsalhornnoci: Nociception after castration of juvenile pigs determined by quantitative estimation of C-fos-expressing neurones in spinal dorsal horn

      Tveden-Nyborg, Pernille, Sørig, A., Lykkegaard, K. & Svendsen, O., 2000, In: Dansk Veterinærtidsskrift. 83, 9, p. 16-17 2 p.

      Research output: Contribution to journal › Journal article › Research

    43. Published

      Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

      Olsen, H. G., Kjeldgaard-Hansen, M., Tveden-Nyborg, Pernille, Birck, M. M., Hammelev, Karsten Pharao, Vegge, A., Aalbæk, Bent, Leifsson, Páll S., Jensen, Henrik Elvang, Iburg, T., Heegaard, P. M. H. & Nielsen, O. L., 2016, In: BMC Research Notes. 9, p. 1-10 10 p., 99.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression

      Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

      Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Dietary Long-Chain Fatty Acids Accelerate Metabolic Dysfunction in Guinea Pigs with Non-Alcoholic Steatohepatitis

      Pedersen, Kamilla, Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2023, In: Nutrients. 15, 2445.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs: [Plus] erratum

      Schjoldager, J. G., Paidi, M. D., Lindblad, M. M., Birck, M. M., Kjærgaard, A. B., Dantzer, V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2015, In: European Journal of Nutrition. 54, 4, p. 667-676 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs

      Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain

      Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease

      Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537

      Research output: Contribution to journal › Review › Research › peer-review

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