European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections
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European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections. / Marques, Cátia; Gama, Luís Telo; Belas, Adriana; Bergström, Karin; Beurlet, Stéphanie; Briend-Marchal, Alexandra; Broens, Els M; Costa, Marta; Criel, Delphine; Damborg, Peter; van Dijk, Marloes A M; van Dongen, Astrid M; Dorsch, Roswitha; Espada, Carmen Martin; Gerber, Bernhard; Kritsepi-Konstantinou, Maria; Loncaric, Igor; Mion, Domenico; Misic, Dusan; Movilla, Rebeca; Overesch, Gudrun; Perreten, Vincent; Roura, Xavier; Steenbergen, Joachim; Timofte, Dorina; Wolf, Georg; Zanoni, Renato Giulio; Schmitt, Sarah; Guardabassi, Luca; Pomba, Constança.
In: BMC Veterinary Research, Vol. 12, 213, 22.09.2016.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections
AU - Marques, Cátia
AU - Gama, Luís Telo
AU - Belas, Adriana
AU - Bergström, Karin
AU - Beurlet, Stéphanie
AU - Briend-Marchal, Alexandra
AU - Broens, Els M
AU - Costa, Marta
AU - Criel, Delphine
AU - Damborg, Peter
AU - van Dijk, Marloes A M
AU - van Dongen, Astrid M
AU - Dorsch, Roswitha
AU - Espada, Carmen Martin
AU - Gerber, Bernhard
AU - Kritsepi-Konstantinou, Maria
AU - Loncaric, Igor
AU - Mion, Domenico
AU - Misic, Dusan
AU - Movilla, Rebeca
AU - Overesch, Gudrun
AU - Perreten, Vincent
AU - Roura, Xavier
AU - Steenbergen, Joachim
AU - Timofte, Dorina
AU - Wolf, Georg
AU - Zanoni, Renato Giulio
AU - Schmitt, Sarah
AU - Guardabassi, Luca
AU - Pomba, Constança
PY - 2016/9/22
Y1 - 2016/9/22
N2 - BACKGROUND: There is a growing concern regarding the increase of antimicrobial resistant bacteria in companion animals. Yet, there are no studies comparing the resistance levels of these organisms in European countries. The aim of this study was to investigate geographical and temporal trends of antimicrobial resistant bacteria causing urinary tract infection (UTI) in companion animals in Europe. The antimicrobial susceptibility of 22 256 bacteria isolated from dogs and cats with UTI was determined. Samples were collected between 2008 and 2013 from 16 laboratories of 14 European countries. The prevalence of antimicrobial resistance of the most common bacteria was determined for each country individually in the years 2012-2013 and temporal trends of bacteria resistance were established by logistic regression.RESULTS: The aetiology of uropathogenic bacteria differed between dogs and cats. For all bacterial species, Southern countries generally presented higher levels of antimicrobial resistance compared to Northern countries. Multidrug-resistant Escherichia coli were found to be more prevalent in Southern countries. During the study period, the level of fluoroquinolone-resistant E. coli isolated in Belgium, Denmark, France and the Netherlands decreased significantly. A temporal increase in resistance to amoxicillin-clavulanate and gentamicin was observed among E. coli isolates from the Netherlands and Switzerland, respectively. Other country-specific temporal increases were observed for fluoroquinolone-resistant Proteus spp. isolated from companion animals from Belgium.CONCLUSIONS: This work brings new insights into the current status of antimicrobial resistance in bacteria isolated from companion animals with UTI in Europe and reinforces the need for strategies aiming to reduce resistance.
AB - BACKGROUND: There is a growing concern regarding the increase of antimicrobial resistant bacteria in companion animals. Yet, there are no studies comparing the resistance levels of these organisms in European countries. The aim of this study was to investigate geographical and temporal trends of antimicrobial resistant bacteria causing urinary tract infection (UTI) in companion animals in Europe. The antimicrobial susceptibility of 22 256 bacteria isolated from dogs and cats with UTI was determined. Samples were collected between 2008 and 2013 from 16 laboratories of 14 European countries. The prevalence of antimicrobial resistance of the most common bacteria was determined for each country individually in the years 2012-2013 and temporal trends of bacteria resistance were established by logistic regression.RESULTS: The aetiology of uropathogenic bacteria differed between dogs and cats. For all bacterial species, Southern countries generally presented higher levels of antimicrobial resistance compared to Northern countries. Multidrug-resistant Escherichia coli were found to be more prevalent in Southern countries. During the study period, the level of fluoroquinolone-resistant E. coli isolated in Belgium, Denmark, France and the Netherlands decreased significantly. A temporal increase in resistance to amoxicillin-clavulanate and gentamicin was observed among E. coli isolates from the Netherlands and Switzerland, respectively. Other country-specific temporal increases were observed for fluoroquinolone-resistant Proteus spp. isolated from companion animals from Belgium.CONCLUSIONS: This work brings new insights into the current status of antimicrobial resistance in bacteria isolated from companion animals with UTI in Europe and reinforces the need for strategies aiming to reduce resistance.
U2 - 10.1186/s12917-016-0840-3
DO - 10.1186/s12917-016-0840-3
M3 - Journal article
C2 - 27658466
VL - 12
JO - B M C Veterinary Research
JF - B M C Veterinary Research
SN - 1746-6148
M1 - 213
ER -
ID: 167478364