TY - JOUR

T1 - Occurrence and clinical significance of Aelurostrongylus abstrusus and other endoparasites in Danish cats

AU - Hansen, Alice P.

AU - Skarbye, Line K.

AU - Vinther, Lene M.

AU - Willesen, Jakob L.

AU - Pipper, Christian B.

AU - Olsen, Caroline S.

AU - Mejer, Helena

PY - 2017/1/30

Y1 - 2017/1/30

N2 - Feline endoparasites are highly prevalent worldwide and may cause a variety of clinical signs in infected cats. Prevalence rates are dynamic and there is limited knowledge of the current prevalence in Denmark and the clinical manifestation and significance of especially the lungworm Aelurostrongylus abstrusus. This study investigated the total and local prevalence of Aelurostrongylus abstrusus and other endoparasites in Danish cats. The clinical significance of feline aelurostrongylosis was also examined through identification of frequency and severity of selected clinical signs. Faecal samples (n = 327) and clinical data (n = 312) were collected from August to October 2015, primarily from outdoor cats located at shelters distributed across Denmark. A modified Baermann method and a concentration McMaster technique was used to diagnose A. abstrusus first stage larvae and eggs/oocysts of other endoparasites. The total A. abstrusus prevalence was 8.3% [95% CI: 5.6–11.9] but local prevalence rates varied from 0% [95% CI: 0.0–8.8] to 31.4% [95% CI: 16.9–49.3]. A rural habitat appeared to increase the risk of A. abstrusus and this accounted for most of the local variation. Furthermore, the risk of infection was lower in kittens younger than 11 weeks compared to older cats (p = 0.002). The cats were also infected with Toxocara cati (44.4% [95% CI: 38.3–50.7]), taeniid species (8.9% [95% CI: 5.7–13.0]), Capillaria aerophila (3.1% [95% CI: 1.3–6.0]), Aonchotheca putorii (3.9% [95% CI: 1.9–7.0]), Cystoisospora felis (3.1% [95% CI: 1.3–6.0]) and Cystoisospora rivolta (2.3% [95% CI: 0.9–5.0]), but there was no difference in local distribution. Co-infection was common, as 66.7% of A. abstrusus infected cats were also infected with one or more other parasites, the most common being T. cati. However, none of these parasites were significantly associated with A. abstrusus. The vast majority of the A. abstrusus infected cats displayed mild to moderate clinical signs. The main symptoms associated with the infection were increased sound on auscultation of the lungs (p = 0.002), increased respiratory rate (p = 0.02), coughing (p = 0.007) and enlarged mandibular lymph nodes (p = 0.002). None of these symptoms were associated with T. cati or C. aerophila which may also affect the lungs. This supports that the symptoms may be related to A. abstrusus and that aelurostrongylosis should be considered an important differential diagnosis in any feline respiratory patient.

AB - Feline endoparasites are highly prevalent worldwide and may cause a variety of clinical signs in infected cats. Prevalence rates are dynamic and there is limited knowledge of the current prevalence in Denmark and the clinical manifestation and significance of especially the lungworm Aelurostrongylus abstrusus. This study investigated the total and local prevalence of Aelurostrongylus abstrusus and other endoparasites in Danish cats. The clinical significance of feline aelurostrongylosis was also examined through identification of frequency and severity of selected clinical signs. Faecal samples (n = 327) and clinical data (n = 312) were collected from August to October 2015, primarily from outdoor cats located at shelters distributed across Denmark. A modified Baermann method and a concentration McMaster technique was used to diagnose A. abstrusus first stage larvae and eggs/oocysts of other endoparasites. The total A. abstrusus prevalence was 8.3% [95% CI: 5.6–11.9] but local prevalence rates varied from 0% [95% CI: 0.0–8.8] to 31.4% [95% CI: 16.9–49.3]. A rural habitat appeared to increase the risk of A. abstrusus and this accounted for most of the local variation. Furthermore, the risk of infection was lower in kittens younger than 11 weeks compared to older cats (p = 0.002). The cats were also infected with Toxocara cati (44.4% [95% CI: 38.3–50.7]), taeniid species (8.9% [95% CI: 5.7–13.0]), Capillaria aerophila (3.1% [95% CI: 1.3–6.0]), Aonchotheca putorii (3.9% [95% CI: 1.9–7.0]), Cystoisospora felis (3.1% [95% CI: 1.3–6.0]) and Cystoisospora rivolta (2.3% [95% CI: 0.9–5.0]), but there was no difference in local distribution. Co-infection was common, as 66.7% of A. abstrusus infected cats were also infected with one or more other parasites, the most common being T. cati. However, none of these parasites were significantly associated with A. abstrusus. The vast majority of the A. abstrusus infected cats displayed mild to moderate clinical signs. The main symptoms associated with the infection were increased sound on auscultation of the lungs (p = 0.002), increased respiratory rate (p = 0.02), coughing (p = 0.007) and enlarged mandibular lymph nodes (p = 0.002). None of these symptoms were associated with T. cati or C. aerophila which may also affect the lungs. This supports that the symptoms may be related to A. abstrusus and that aelurostrongylosis should be considered an important differential diagnosis in any feline respiratory patient.

U2 - 10.1016/j.vetpar.2016.12.015

DO - 10.1016/j.vetpar.2016.12.015

M3 - Journal article

C2 - 28115180

VL - 234

SP - 31

EP - 39

JO - Veterinary Parasitology

JF - Veterinary Parasitology

SN - 0304-4017

ER -