Kristine Freude
Associate Professor
Pathobiological Sciences
Grønnegårdsvej 7, 1870 Frederiksberg C, 1-04
My current research interests are induced pluipotent cells (iPSC) from pigs and humans.
Regarding the porcine iPSC I am working on making naive pluripotent stem cells which are able to generate chimeras. Furthermore, I am comparing the pluripotent state of porcine iPSC to porcine embryos via RNAseq to understand similarities and discrepancies in regards to pluripotency.
I am interested in neurodegenerative disorder in particular Alzheimer's disease and frontotemporal dementia. I am using patient specific iPSC and differentiate these into disease relevant neuronal subtypes to investigate the underlying disaese mechanisms.
ID: 38189431
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683
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Induced pluripotent stem cells derived from Alzheimer's disease patients: the promise, the hope and the path ahead
Research output: Contribution to journal › Review › Research › peer-review
Published -
581
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Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
204
downloads
Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B
Research output: Contribution to journal › Journal article › Research › peer-review
Published