The section consists of 5 research groups: Pathology, Pathology of small animals and wild life, Disease Stem Cell Models and Embryology, Brain Development and Disease and Physiology. 

Pathology - Henrik Elvang Jensen

Research areas: Animal welfare, lesions and inflammation, animal diseases, diagnostic pathology, comparative infection pathology, fungi, virus, parasite and bacteria infections, animal models, implants, biofilm and alternatives for antibiotics. 

• Professor Henrik Elvang Jensen,
• Associate professor Páll Leifsson,
• Associate professor Louise Kruse Jensen,
• Associate professor Mette Sif Hansen,
• Assistant professor Kristiane Barington

Small Animal and wild life pathology - Anne Sofie Hammer

Research area: Contingency and notifiable animal diseases, diagnostics of and surveillance of fur animals, wild life pathology and surveillance, gut health and microbiota, wound infections and biofilm in wounds, alternatives to antibiotics (probiotica, wound treatment, selection and immunological toughness). 

Disease Stem Cell Models and Embryology - Kristine Freude

Research area: Our group is focused on disease modelling using state of the art stem cell approaches for neurodegenerative diseases (Alzheimer’s disease, Frontotemporal dementia, Parkinson’s disease), Epilepsy and Glaucoma. These projects work with human induced pluripotent stem cells (iPSC), CRISPR/Cas9 gene editing neuronal and glial differentiation and downstream analyses in 2D and 3D organoids.

Likewise, we are interested in iPSC models from animals and we are running projects making canine iPSC to understand and make in vitro models of canine cognitive dysfunction as well as making immune-evasive porcine iPSC to improve transplantation studies.

Our research on cerebral vascular (dys-)function in hypertension, aging and obesity/diabetes is focused on their significance as risk factors for several types of dementia, including vascular dementia and Alzheimer’s Disease.

Our focus in embryology is on early events in oocyte and sperm development, reproduction and manipulation of such events to increase life stock sustainability and animal welfare. 

• Associate professor Kristine Freude - Stem Cells Models for Studies of Neurodegenerative Diseases
• Professor Poul Hyttel - Animal Stem Cells and Embryology 
• Associate professor Esben Østrup - Biochemistry 
• Associate professor Lars Jørn Jensen - Cerebrovascular Physiology
• Professor Preben Dybdahl Thomsen

Brain Development and Disease - Vanessa Hall

Research area: The group of Brain Development and Disease’s primary vision is to determine novel mechanisms involved in neurodevelopment and neurodegenerative diseases. Our primary research is currently focused on the cellular mapping of the developing entorhinal cortex (the brain’s spatial navigation and processing system). We also use pluripotent and neural stem cells, as well brains from the human and pig to model human brain development and to investigate diseases, such as Alzheimer’s disease. The group incorporates cutting edge technologies, including, single cell RNA sequencing and direct programming of stem cells to produce different brain cells in a dish from both healthy and diseased individuals.

Physiology - Dan Klærke

Comparative cardiology, excitable cells, Ion channels, Biomechanics and myofascies, comparative anatomy.

• Professor Dan Klærke,
• Associate professor Kirstine Callø,
• Associate professor Vibeke Sødring Elbrønd,
• Associate professor Adrian Harrison