Section for Pathobiological Sciences

The section for Pathobiological Sciences is a part of the Department for Veterinary and Animal Sciences (IVH) at the University of Copenhagen.

Decorative illustration

PAS is dedicated to;

  • Research on a high, international level within embryology and stem cells, animal welfare, disease models, electro physiology, pathogenesis evaluation and veterinary pathological diagnostics, and in this way contribute to diagnostics and treatment of sick humans and animals.
  • Teaching. The teaching of the section is vital to the veterinary bachelor and master programme and to the Animal Science programme. We prepare the students for research, diagnostics and clinical work. We educate master students and PhD students on a high, international level within the research areas of the section.
  • Veterinary Contingency, partly consulting cases for the Danish Veterinary and Food Administration, partly veterinary Contingency which receives all cadavers and organs for observation of notifiable animal diseases. Furthermore we are responsible for the surveillance of cattle abortion and the surveillance of TSE (BSE and scrapie) in Denmark.

Students are always welcome to contact us for available projects.

 

 

 

 

 

The section consists of 5 research groups: Pathology, Pathology of small animals and wild life, Disease Stem Cell Models and Embryology, Brain Development and Disease and Physiology. 

Veterinary Pathology - Henrik Elvang Jensen

Drawing of the entrance to pathologyResearch areas: Animal welfare, lesions and inflammation, animal diseases, diagnostic pathology, comparative infection pathology, fungi, virus, parasite and bacteria infections, animal models, implants, biofilm and alternatives for antibiotics. 

  • Professor Henrik Elvang Jensen,
  • Associate professor Páll Leifsson,
  • Associate professor Louise Kruse Jensen,
  • Associate professor Mette Sif Hansen,
  • Assistant professor Kristiane Barington

Small Animal and Wild Life Pathology - Anne Sofie Hammer

Research area: Contingency and notifiable animal diseases, diagnostics of and surveillance of fur animals, wild life pathology and surveillance, gut health and microbiota, wound infections and biofilm in wounds, alternatives to antibiotics (probiotica, wound treatment, selection and immunological toughness). 


Disease Stem Cell Models and Embryology - Kristine Freude

Research area: Our group is focused on disease modelling using state of the art stem cell approaches for neurodegenerative diseases (Alzheimer’s disease, Frontotemporal dementia, Parkinson’s disease), Epilepsy and Glaucoma. These projects work with human induced pluripotent stem cells (iPSC), CRISPR/Cas9 gene editing neuronal and glial differentiation and downstream analyses in 2D and 3D organoids.

Likewise, we are interested in iPSC models from animals and we are running projects making canine iPSC to understand and make in vitro models of canine cognitive dysfunction as well as making immune-evasive porcine iPSC to improve transplantation studies.

Our research on cerebral vascular (dys-)function in hypertension, aging and obesity/diabetes is focused on their significance as risk factors for several types of dementia, including vascular dementia and Alzheimer’s Disease.

Our focus in embryology is on early events in oocyte and sperm development, reproduction and manipulation of such events to increase life stock sustainability and animal welfare. 


Brain Development and Disease - Vanessa Hall

Research area: The group of Brain Development and Disease’s primary vision is to determine novel mechanisms involved in neurodevelopment and neurodegenerative diseases. Our primary research is currently focused on the cellular mapping of the developing entorhinal cortex (the brain’s spatial navigation and processing system). We also use pluripotent and neural stem cells, as well brains from the human and pig to model human brain development and to investigate diseases, such as Alzheimer’s disease. The group incorporates cutting edge technologies, including, single cell RNA sequencing and direct programming of stem cells to produce different brain cells in a dish from both healthy and diseased individuals.


Physiology - Dan Klærke

Drawing of researcher at microscopeComparative cardiology, excitable cells, Ion channels, Biomechanics and myofascies, comparative anatomy.

  • Professor Dan Klærke,
  • Associate professor Kirstine Callø,
  • Associate professor Vibeke Sødring Elbrønd,
  • Associate professor Adrian Harrison

 

 

We have highly specialised Core facilities which perform diagnostic pathology, stem cell technologies.

Pathology CORE

The Histo-Laboratory assists scientists in processing tissue samples for histochemical and molecular based procedures. In the Histo-Laboratory state-of the art histotechnology is offered by a team of specialized technicians.

In research projects, optimal results are obtained when the laboratory is contacted as early as possible in the planning of the in vivo part of the project; allowing the technicians to help determine how histological approach can best support the research aim.

Paraffin embedding, sectioning and staining of tissues. Embedding and sectioning services are based on standard protocols. Tissues are fixed and embedded in paraffin blocks, which are used for a variety of analyses, e.g., histochemical staining (HE, PAS, GMS etc.), immunohistochemistry (IHC), and in-situ hybridization (ISH), PCR, etc. Apart from stained sections, also paraffin blocks and the unstained sections can be provided. 

Kontakt: Betina Andersen, bean@sund.ku.dk eller Elisabeth Petersen, ewp@sund.ku.dk. Tlf 35333106.


Veterinary contingency

Contact information:

The veterinary contingency - phone number 9350 9280 - can be contacted 8:00-16:00 on working days. 

Non urgent inquiries can be mailed to: kupat@sund.ku.dk  

Contact person: Anne- Sofie Hammer, hammer@sund.ku.dk


Stem cell and TEM core


Anubis Core

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Head of Section Kirstine Callø

Head of Section

Kirstine Callø
Associate Professor

Phone +45 61 66 64 02
kirstinec@sund.ku.dk

Employees at Section

Internal researchers

Name Title Phone E-mail
Andersen, Betina Gjedsted Biomedical Laboratory Scientist +4535336737 E-mail
Andersen, Frederik Attendant FU +4535336735 E-mail
Barington, Kristiane Assistant Professor +4535333112 E-mail
Becker, Cecilie Brandt Research Assistant +4535337580 E-mail
Blirup-Plum, Sophie Amalie PhD Fellow +4535331513 E-mail
Blok-Husum, Emma Teacher´s Assistant   E-mail
Bredum, Simon Krogh Veterinarian   E-mail
Brok, Dennis Attendant FU +4535333101 E-mail
Cakal, Selgin Deniz External, Ph.d Student +4581930536 E-mail
Callø, Kirstine Associate Professor +4561666402 E-mail
Chandrasekaran, Abinaya Postdoc +4535328080 E-mail
Christensen, Jonathan Ingerslev Teacher´s Assistant   E-mail
Christensen, Signe Leth Teacher´s Assistant   E-mail
Christensen, Vibeke Grøsfjeld Laboratory Technician +4535332562 E-mail
Christiansen, Ida Højager Attendant FU   E-mail
Christoffersen, Maria Juul Teacher´s Assistant   E-mail
Eidsmo, Julia Thyra Wood Teacher´s Assistant   E-mail
Eiersted, Anna Cecilie Boldt Laboratory Technician +4535337069 E-mail
Elbrønd (Bibs), Vibeke Sødring Associate Professor +4535332548 E-mail
Fenner, Merle Friederike Postdoc +4535333300 E-mail
Fenner, Merle Friederike Assistant Professor +4535333300 E-mail
Freude, Kristine Associate Professor +4535330937 E-mail
Gad, Mathilde Teacher´s Assistant   E-mail
Gulmann, Adam Teacher´s Assistant   E-mail
Hall, Vanessa Jane Associate Professor +4535332512 E-mail
Hammer, Anne Sofie Vedsted Associate Professor +4535333129 E-mail
Hansen, Laura Signe Wiberg Teacher´s Assistant   E-mail
Hansen, Mette Sif Associate Professor +4535326468 E-mail
Hansen, Vibeke Bøgelund Attendant +4523828066 E-mail
Harrison, Adrian Paul Associate Professor +4561462732 E-mail
Hartmann, Katrine Top Research Assistant +4535331206 E-mail
Hashem, Nadia No job title   E-mail
Haukedal, Henriette PhD Fellow +4535325288 E-mail
Honoré, Oliver Legarth PhD Student +4535335018 E-mail
Hovmand-Hansen, Trine PhD Fellow +4535331443 E-mail
Hvidtfeldt, Esther Johanne Teacher´s Assistant   E-mail
Hyttel, Poul Professor +4535332541 E-mail
Iburg, Tine Moesgaard Teacher, external   E-mail
Jensen, Henrik Elvang Professor +4535333100 E-mail
Jensen, Jan Lykke Attendant +4523828065 E-mail
Jensen, Lars Jørn Associate Professor +4535332563 E-mail
Jensen, Louise Kruse Associate Professor +4535336192 E-mail
Kamstrup, Kristian Møgeltoft No job title   E-mail
Klærke, Dan Arne Professor +4535332511 E-mail
Kragh, Benedicte Section Secratary +4535333105 E-mail
Kromann, Sofie Industrial PhD +4535326918 E-mail
Larsen, Jakob Overgaard Teacher´s Assistant +4528727717 E-mail
Leifsson, Páll Skúli Associate Professor +4535333114 E-mail
Mohamed, Fadumo Abdullahi Research Assistant +4535325198 E-mail
Mundbjerg, Karin No job title VIP +4535323251 E-mail
Møller, Steffen Kjær Hemmingsen Teacher´s Assistant   E-mail
Møller-Petersen, Mathilde Luth Teacher´s Assistant   E-mail
Najafzadeh, Vahid Postdoc   E-mail
Nielsen, Ole Lerberg No job title VIP   E-mail
Olesen, Sasja Teacher´s Assistant   E-mail
Pankoke, Karen PhD Student   E-mail
Pankoke, Karen PhD Fellow   E-mail
Pedersen, Line Bøgelund Teacher´s Assistant   E-mail
Petersen, Elisabeth Wairimu Laboratory Technician +4535336757 E-mail
Pihl, Maria Laboratory Technician +4522496408 E-mail
Poulsen, Knud No job title VIP +4524204511 E-mail
Quaade, Michelle Lauge PhD Fellow +4535334685 E-mail
Saruhanian, Sarkis PhD Fellow +4535327472 E-mail
Skandov, Nicoline Siebken Teacher´s Assistant   E-mail
Synnestvedt, Josefine Natalie Teacher´s Assistant   E-mail
Sønderby, Laura Teacher´s Assistant   E-mail
Thomsen, Preben Dybdahl Professor +4535332545 E-mail
Vohra, Rupali Postdoc +4551331248 E-mail
Wagner, Nicklas Student   E-mail
Wolf-Jäckel, Godelind Alma Assistant Professor +4535320521 E-mail
Østrup, Esben Associate Professor +4535334743 E-mail