Characterizing new rodent knockout models within haemostasis and inflammation
These projects are mainly PhD projects, where we at present characterize:
a rat made deficient of the coagulation factor VII as a model of long-term complications of haemophilia,
a rat model made deficient of the transport protein APOE, as a model of atherosclerosis,
a mouse made deficient of the cytokine TL1A as a model of reducing type 2 diabetes and obesity,
and a mouse made deficient of the cytokine IL-10 as a model of inflammatory bowel disease.