Graham John Belsham
Professor
Veterinary Clinical Microbiology
Stigbøjlen 4
1870 Frederiksberg C
- 2018
Cleavages at the three junctions within the foot-and-mouth disease virus capsid precursor (P1-2A) by the 3C protease are mutually independent
Kristensen, Thea, Newman, J., Guan, S. H., Tuthill, T. J. & Belsham, Graham John, Sep 2018, In: Virology. 522, p. 260-270 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Complete genome sequence of an African swine fever virus (ASFV POL/2015/Podlaskie) determined directly from pig erythrocyte-associated nucleic acid
Olesen, A. S., Lohse, L., Dalgaard, M. D., Woźniakowski, G., Belsham, Graham John, Bøtner, A. & Rasmussen, T. B., Nov 2018, In: Journal of Virological Methods. 261, p. 14-16 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Full-length genome sequences of porcine epidemic diarrhoea virus strain CV777; Use of NGS to analyse genomic and sub-genomic RNAs
Rasmussen, T. B., Boniotti, M. B., Papetti, A., Grasland, B., Frossard, J., Dastjerdi, A., Hulst, M., Hanke, D., Pohlmann, A., Blome, S., van der Poel, W. H. M., Steinbach, F., Blanchard, Y., Lavazza, A., Bøtner, A. & Belsham, Graham John, 2018, In: PLoS ONE. 13, 3, p. e0193682Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
Separation of foot-and-mouth disease virus leader protein activities; identification of mutants that retain efficient self-processing activity but poorly induce eIF4G cleavage
Guan, S. H. & Belsham, Graham John, Apr 2017, In: The Journal of general virology. 98, 4, p. 671-680 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Experimental Infection of Young Pigs with an Early European Strain of Porcine Epidemic Diarrhoea Virus and a Recent US Strain
Lohse, L., Krog, J. S., Strandbygaard, B., Rasmussen, T. B., Kjaer, J., Belsham, Graham John & Bøtner, A., Oct 2017, In: Transboundary and Emerging Diseases. 64, 5, p. 1380-1386 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
Development and evaluation of tailored specific real-time RT-PCR assays for detection of foot-and-mouth disease virus serotypes circulating in East Africa
Bachanek-Bankowska, K., Mero, H. R., Wadsworth, J., Mioulet, V., Sallu, R., Belsham, Graham John, Kasanga, C. J., Knowles, N. J. & King, D. P., Nov 2016, In: Journal of Virological Methods. 237, p. 114-120 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Characterization of a Novel Chimeric Swine Enteric Coronavirus from Diseased Pigs in Central Eastern Europe in 2016
Belsham, Graham John, Rasmussen, T. B., Normann, P., Vaclavek, P., Strandbygaard, B. & Bøtner, A., Dec 2016, In: Transboundary and Emerging Diseases. 63, 6, p. 595-601 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Assessing the potential spread and maintenance of foot-and-mouth disease virus infection in wild ungulates: general principles and application to a specific scenario in Thrace
Dhollander, S., Belsham, Graham John, Lange, M., Willgert, K., Alexandrov, T., Chondrokouki, E., Depner, K., Khomenko, S., Özyörük, F., Salman, M., Thulke, H. H. & Bøtner, A., Apr 2016, In: Transboundary and Emerging Diseases. 63, 2, p. 165-74 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid Particles
Gullberg, M., Lohse, L., Bøtner, A., McInerney, G. M., Burman, A., Jackson, T., Polacek, C. & Belsham, Graham John, 2016, In: PLoS ONE. 11, 6, p. e0157435Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Use of recombinant capsid proteins in the development of a vaccine against the foot-and-mouth disease virus
Belsham, Graham John & Bøtner, A., 2015, In: Virus Adaptation and Treatment.Research output: Contribution to journal › Journal article › Research › peer-review
Development and Characterization of Probe-Based Real Time Quantitative RT-PCR Assays for Detection and Serotyping of Foot-And-Mouth Disease Viruses Circulating in West Eurasia
Jamal, S. M. & Belsham, Graham John, 2015, In: PLoS ONE. 10, 8, e0135559.Research output: Contribution to journal › Journal article › Research › peer-review
Identification and complete genome analysis of a novel bovine picornavirus in Japan
Nagai, M., Omatsu, T., Aoki, H., Kaku, Y., Belsham, Graham John, Haga, K., Naoi, Y., Sano, K., Umetsu, M., Shiokawa, M., Tsuchiaka, S., Furuya, T., Okazaki, S., Katayama, Y., Oba, M., Shirai, J., Katayama, K. & Mizutani, T., 2 Dec 2015, In: Virus Research. 210, p. 205-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
Characteristics of a foot-and-mouth disease virus with a partial VP1 G-H loop deletion in experimentally infected cattle
Fowler, V., Bashiruddin, J. B., Belsham, Graham John, Stenfeldt, C., Bøtner, A., Knowles, N. J., Bankowski, B., Parida, S. & Barnett, P., 21 Feb 2014, In: Veterinary Microbiology. 169, 1-2, p. 58-66 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Sequence adaptations affecting cleavage of the VP1/2A junction by the 3C protease in foot-and-mouth disease virus-infected cells
Gullberg, M., Polacek, C. & Belsham, Graham John, Nov 2014, In: The Journal of general virology. 95, Pt 11, p. 2402-2410 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Development of tailored real-time RT-PCR assays for the detection and differentiation of serotype O, A and Asia-1 foot-and-mouth disease virus lineages circulating in the Middle East
Reid, S. M., Mioulet, V., Knowles, N. J., Shirazi, N., Belsham, Graham John & King, D. P., Oct 2014, In: Journal of Virological Methods. 207, p. 146-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Full-length genomic analysis of Korean porcine Sapelovirus strains
Son, K., Kim, D., Kwon, J., Choi, J., Kang, M., Belsham, Graham John & Cho, K., 2014, In: PLoS ONE. 9, 9, p. e107860Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Influence of the Leader protein coding region of foot-and-mouth disease virus on virus replication
Belsham, Graham John, Jul 2013, In: The Journal of general virology. 94, Pt 7, p. 1486-1495 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foot-and-mouth disease virus serotype O phylodynamics: genetic variability associated with epidemiological factors in Pakistan
Brito, B. P., Gonzalez-Perez, Alfredo, Jamal, S. M., Belsham, Graham John, Pauszek, S. J., Ahmed, Z. & Rodriguez, L. L., Dec 2013, In: Transboundary and Emerging Diseases. 60, 6, p. 516-24 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assembly and characterization of foot-and-mouth disease virus empty capsid particles expressed within mammalian cells
Gullberg, M., Muszynski, B., Organtini, L. J., Ashley, R. E., Hafenstein, S. L., Belsham, Graham John & Polacek, C., Aug 2013, In: The Journal of general virology. 94, Pt 8, p. 1769-1779 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Processing of the VP1/2A junction is not necessary for production of foot-and-mouth disease virus empty capsids and infectious viruses: characterization of "self-tagged" particles
Gullberg, M., Polacek, C., Bøtner, A. & Belsham, Graham John, Nov 2013, In: Journal of Virology. 87, 21, p. 11591-603 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foot-and-mouth disease: past, present and future
Jamal, S. M. & Belsham, Graham John, 2013, In: Veterinary Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low levels of foot-and-mouth disease virus 3C protease expression are required to achieve optimal capsid protein expression and processing in mammalian cells
Polacek, C., Gullberg, M., Li, J. & Belsham, Graham John, Jun 2013, In: The Journal of general virology. 94, Pt 6, p. 1249-1258 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity
Porta, C., Xu, X., Loureiro, S., Paramasivam, S., Ren, J., Al-Khalil, T., Burman, A., Jackson, T., Belsham, G. J., Curry, S., Lomonossoff, G. P., Parida, S., Paton, D., Li, Y., Wilsden, G., Ferris, N., Owens, R., Kotecha, A., Fry, E., Stuart, D. I. & 2 others, , Feb 2013, In: Journal of Virological Methods. 187, 2, p. 406-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transplacental transmission of field and rescued strains of BTV-2 and BTV-8 in experimentally infected sheep
Rasmussen, L. D., Savini, G., Lorusso, A., Bellacicco, A., Palmarini, M., Caporale, M., Rasmussen, T. B., Belsham, Graham John & Bøtner, A., 5 Sep 2013, In: Veterinary Research. 44, p. 75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The comparative utility of oral swabs and probang samples for detection of foot-and-mouth disease virus infection in cattle and pigs
Stenfeldt, C., Lohse, L. & Belsham, Graham John, 23 Mar 2013, In: Veterinary Microbiology. 162, 2-4, p. 330-337 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Virus survival in slurry: analysis of the stability of foot-and-mouth disease, classical swine fever, bovine viral diarrhoea and swine influenza viruses
Bøtner, A. & Belsham, Graham John, 25 May 2012, In: Veterinary Microbiology. 157, 1-2, p. 41-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Modulation of Translation Initiation Efficiency in Classical Swine Fever Virus
Friis, M. B., Rasmussen, T. B. & Belsham, Graham John, 2012, In: Journal of Virology. 86, 16, p. 8681-8692 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection and genetic characterization of foot-and-mouth disease viruses in samples from clinically healthy animals in endemic settings
Jamal, S. M., Ferrari, G., Hussain, M., Nawroz, A. H., Aslami, A. A., Khan, E., Murvatulloev, S., Ahmed, S. & Belsham, Graham John, Oct 2012, In: Transboundary and Emerging Diseases. 59, 5, p. 429-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Capsid coding sequences of foot-and-mouth disease viruses are determinants of pathogenicity in pigs
Lohse, L., Jackson, T., Bøtner, A. & Belsham, Graham John, 24 May 2012, In: Veterinary Research. 43, p. 46Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of foot-and-mouth disease virus RNA in pharyngeal epithelium biopsy samples obtained from infected cattle: investigation of possible sites of virus replication and persistence
Stenfeldt, C. & Belsham, Graham John, 27 Jan 2012, In: Veterinary Microbiology. 154, 3-4, p. 230-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reconstruction of the transmission history of RNA virus outbreaks using full genome sequences: foot-and-mouth disease virus in Bulgaria in 2011
Valdazo-González, B., Polihronova, L., Alexandrov, T., Normann, P., Knowles, N. J., Hammond, J. M., Georgiev, G. K., Özyörük, F., Sumption, K. J., Belsham, Graham John & King, D. P., 2012, In: PLoS ONE. 7, 11, p. e49650Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Rescue of foot-and-mouth disease viruses that are pathogenic for cattle from preserved viral RNA samples
Belsham, Graham John, Jamal, S. M., Tjørnehøj, K. & Bøtner, A., 28 Jan 2011, In: PLoS ONE. 6, 1, p. e14621Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Capsid proteins from field strains of foot-and-mouth disease virus confer a pathogenic phenotype in cattle on an attenuated, cell-culture-adapted virus
Bøtner, A., Kakker, N. K., Barbezange, C., Berryman, S., Jackson, T. & Belsham, Graham John, May 2011, In: The Journal of general virology. 92, Pt 5, p. 1141-1151 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary analysis of serotype A foot-and-mouth disease viruses circulating in Pakistan and Afghanistan during 2002-2009
Jamal, S. M., Ferrari, G., Ahmed, S., Normann, P., Curry, S. & Belsham, Graham John, Dec 2011, In: The Journal of general virology. 92, Pt 12, p. 2849-2864 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic diversity of foot-and-mouth disease virus serotype O in Pakistan and Afghanistan, 1997-2009
Jamal, S. M., Ferrari, G., Ahmed, S., Normann, P. & Belsham, Graham John, Aug 2011, In: Infection, Genetics and Evolution. 11, 6, p. 1229-38 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular characterization of serotype Asia-1 foot-and-mouth disease viruses in Pakistan and Afghanistan; emergence of a new genetic Group and evidence for a novel recombinant virus
Jamal, S. M., Ferrari, G., Ahmed, S., Normann, P. & Belsham, Graham John, Dec 2011, In: Infection, Genetics and Evolution. 11, 8, p. 2049-62 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of cytokine mRNA expression in pharyngeal epithelial samples obtained from cattle infected with foot-and-mouth disease virus
Stenfeldt, C., Heegaard, P. M. H., Stockmarr, A. & Belsham, Graham John, 27 Aug 2011, In: Journal of Comparative Pathology. 146, 2-3, p. 243-52 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of the acute phase responses of serum amyloid a, haptoglobin and type 1 interferon in cattle experimentally infected with foot-and-mouth disease virus serotype O
Stenfeldt, C., Heegaard, P. M. H., Stockmarr, A., Tjørnehøj, K. & Belsham, Graham John, 18 May 2011, In: Veterinary Research. 42, p. 66Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural features of the Seneca Valley virus internal ribosome entry site (IRES) element: a picornavirus with a pestivirus-like IRES
Willcocks, M. M., Locker, N., Gomwalk, Z., Royall, E., Bakhshesh, M., Belsham, Graham John, Idamakanti, N., Burroughs, K. D., Reddy, P. S., Hallenbeck, P. L. & Roberts, L. O., May 2011, In: Journal of Virology. 85, 9, p. 4452-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
Detection of myxoma viruses encoding a defective M135R gene from clinical cases of myxomatosis; Possible implications for the role of the M135R protein as a virulence factor
Belsham, Graham John, Polacek, C., Breum, S., Larsen, Lars & Bøtner, A., 2010, In: Virology Journal. 7, 7.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bluetongue in Denmark during 2008
Rasmussen, L. D., Rasmussen, T. B., Belsham, Graham John, Strandbygaard, B. & Bøtner, A., 5 Jun 2010, In: The Veterinary Record. 166, 23, p. 714-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foot-and-mouth disease virus 2C is a hexameric AAA+ protein with a coordinated ATP hydrolysis mechanism
Sweeney, T. R., Cisnetto, V., Bose, D., Bailey, M., Wilson, J. R., Zhang, X., Belsham, Graham John & Curry, S., 6 Aug 2010, In: The Journal of Biological Chemistry. 285, 32, p. 24347-59 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into cleavage specificity from the crystal structure of foot-and-mouth disease virus 3C protease complexed with a peptide substrate
Zunszain, P. A., Knox, S. R., Sweeney, T. R., Yang, J., Roqué-Rosell, N., Belsham, Graham John, Leatherbarrow, R. J. & Curry, S., 15 Jan 2010, In: Journal of Molecular Biology. 395, 2, p. 375-89 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Divergent picornavirus IRES elements
Belsham, Graham John, Feb 2009, In: Virus Research. 139, 2, p. 183-92 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A dominant-negative mutant of rab5 inhibits infection of cells by foot-and-mouth disease virus: implications for virus entry
Johns, H. L., Berryman, S., Monaghan, P., Belsham, Graham John & Jackson, T., Jun 2009, In: Journal of Virology. 83, 12, p. 6247-56 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Foot-and-mouth disease virus, but not bovine enterovirus, targets the host cell cytoskeleton via the nonstructural protein 3Cpro
Armer, H., Moffat, K., Wileman, T., Belsham, Graham John, Jackson, T., Duprex, W. P., Ryan, M. & Monaghan, P., Nov 2008, In: Journal of Virology. 82, 21, p. 10556-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The picornavirus avian encephalomyelitis virus possesses a hepatitis C virus-like internal ribosome entry site element
Bakhshesh, M., Groppelli, E., Willcocks, M. M., Royall, E., Belsham, Graham John & Roberts, L. O., Feb 2008, In: Journal of Virology. 82, 4, p. 1993-2003 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of picornavirus RNA replication within infected cells
Belsham, Graham John & Normann, P., Feb 2008, In: The Journal of general virology. 89, Pt 2, p. 485-493 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monocistronic mRNAs containing defective hepatitis C virus-like picornavirus internal ribosome entry site elements in their 5' untranslated regions are efficiently translated in cells by a cap-dependent mechanism
Belsham, Graham John, Nielsen, I., Normann, P., Royall, E. & Roberts, L. O., Aug 2008, In: R N A. 14, 8, p. 1671-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Identification of minimal sequences of the Rhopalosiphum padi virus 5' untranslated region required for internal initiation of protein synthesis in mammalian, plant and insect translation systems
Groppelli, E., Belsham, Graham John & Roberts, L. O., May 2007, In: The Journal of general virology. 88, Pt 5, p. 1583-1588 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 223344837
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SARS-CoV-2 in Danish Mink Farms: Course of the Epidemic and a Descriptive Analysis of the Outbreaks in 2020
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Virus adaptation and selection following challenge of animals vaccinated against classical swine fever virus
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Coronavirus i danske produktionsdyr, kæledyr og vilde dyre
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