Kristine Freude
Professor
Pathobiological Sciences
Grønnegårdsvej 7, 1870 Frederiksberg C
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3D-organization and spatial localization of chromatin and epigenetic marks in relation to nucleolar activity in porcine oocytes
Fenner, Merle Friederike, Benc, M., Rosenbaum Bartkova , A., Pihl, M., Chebrout, M., Freude, Kristine, Strejeck, F., Hyttel, P., Lucas-Hahn, A., Laurincik, J. & Bonnet-Garnier, A., 2023. 1 p.Research output: Contribution to conference › Poster › Research › peer-review
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FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms
Dittlau, Katarina Stoklund, Terrie, L., Baatsen, P., Kerstens, A., De Swert, L., Janky, R., Corthout, N., Masrori, P., Van Damme, P., Hyttel, P., Meyer, M., Thorrez, L., Freude, Kristine & Van Den Bosch, L., 2023, In: Molecular Neurodegeneration. 18, 1, 5.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro production of bovine embryos: revisiting oocyte development and application of systems biology
Stroebech, L., Mazzoni, G., Pedersen, H. S., Freude, Kristine, Kadarmideen, H., Callesen, H. & Hyttel, P., 1 Aug 2015, In: Animal Reproduction. 12, 3, p. 465-472 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity
Seymour, Philip Allan, Shih, H. P., Patel, N. A., Freude, Kristine, Xie, R., Lim, C. J. & Sander, M., Sep 2012, In: Development. 139, 18, p. 3363-72 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
Seymour, Philip Allan, Freude, Kristine, Dubois, C. L., Shih, H., Patel, N. A. & Sander, M., 1 Nov 2008, In: Advances in Developmental Biology. 323, 1, p. 19-30 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A protein-centric view of in vitro biological model systems for schizophrenia
Chandrasekaran, Abinaya, Jensen, P., Mohamed, Fadumo Abdullahi, Lancaster, M., Benros, Michael Eriksen, Larsen, M. R. & Freude, Kristine, 2021, In: Stem Cells. 39, 12, p. 1569-1578Research output: Contribution to journal › Review › Research › peer-review
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APOE4 IS INSTRUMENTAL IN AUGMENTING RHOA KINASE PHOSPHORYLATION AND CONTRIBUTES THEREBY TO CLASSICAL ALZHEIMER’S DISEASE NEURON PHENOTYPES
Freude, Kristine, Dittlau, Katarina Stoklund & Tao, Ruixin, 5 Mar 2024.Research output: Contribution to conference › Conference abstract for conference › Communication
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APOE4 affects basal and NMDAR mediated protein synthesis in neurons by perturbing calcium homeostasis
Ramakrishna, S., Jhaveri, V., Konings, S. C., Nawalpuri, B., Chakraborty, S., Holst, B., Schmid, B., Gouras, G. K., Freude, Kristine & Muddashetty, R. S., 2021, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 41, 42, p. 8686-8709Research output: Contribution to journal › Journal article › Research › peer-review
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Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3
Haukedal, H., Syshøj Lorenzen, S., Westi, Emil Winther, Corsi, G., Gadekar, V. P., McQuade, A., Davtyan, H., Doncheva, Nadezhda Tsankova, Schmid, B., Chandrasekaran, Abinaya, Seemann, Ernst Stefan, Cirera, Susanna, Blurton-Jones, M., Meyer, M., Gorodkin, Jan, Aldana, Blanca & Freude, Kristine, 2023, In: Brain, Behavior, and Immunity. 113, p. 353-373Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of porcine-induced pluripotent stem cells by in vivo assays
Secher, Jan Bojsen-Møller, Freude, Kristine, Petkov, S. G., Ceylan, A., Schmidt, M. & Hyttel, P., 1 Dec 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Astrocytes: The Stars in Neurodegeneration?
Dittlau, Katarina Stoklund & Freude, Kristine, 28 Feb 2024, In: Biomolecules.Research output: Contribution to journal › Journal article › Research › peer-review
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Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3
Chandrasekaran, A., Dittlau, K. S., Corsi, G. I., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Zhang, Y., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J. E., Kolko, M., Kobolák, J., Dinnyés, A., Hyttel, P., Palakodeti, D. & 5 others, , 2021, In: Stem Cell Reports. 16, 11, p. 2736-2751Research output: Contribution to journal › Journal article › Research › peer-review
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CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice
Frederiksen, Henriette Reventlow S, Glantz, A., Vøls, K. K., Skov, Søren, Tveden-Nyborg, Pernille, Freude, Kristine & Doehn, U., 28 May 2024, In: Frontiers in Genome Editing. 6Research output: Contribution to journal › Journal article › Research › peer-review
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Canine induced pluripotent stem cells: An in vitro approach to validate the dog as a large animal model for Alzheimer’s disease
De Figueiredo Pessôa, L. V., Chandrasekaran, Abinaya, Thomsen, B. B., Berendt, Mette, Hyttel, P. & Freude, Kristine, 2020, iPSCs from Diverse Species. Academic Press, p. 77-91 15 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Canine induced pluripotent stem cells: an in vitro approach to validate the dog as a large animal model for Alzheimer's disease
Pessoa, L. V. D. F., Chandrasekaran, Abinaya, Thomsen, B. B., Berendt, Mette, Hyttel, P. & Freude, Kristine, Sep 2020, iPSCs from Diverse Species. 1 ed. Elsevier: Academic Press, Vol. 2.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Cell type specific expression of toll-like receptors in human brains and implications in Alzheimer's disease
Frederiksen, Henriette Reventlow S, Haukedal, H. & Freude, Kristine, 2019, In: BioMed Research International. 2019, 18 p., 7420189.Research output: Contribution to journal › Review › Research › peer-review
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Cellular bioenergetics in human iPSC-derived glutamatergic neurons in health and disease
Aldana, Blanca, Salcedo, C., Freude, Kristine & Waagepetersen, Helle S., 2021, Current Progress in iPSC-derived Cell Types. Birbrair, A. (ed.). Elsevier, p. 205-221 17 p. (Advances in Stem Cell Biology, Vol. 10).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Challenges in Establishing Animal Induced Pluripotent Stem Cells
Enevoldsen, Sara, Magnusson, H. B. D., Lind, J. U., Freude, Kristine & Callø, Kirstine, 15 Sep 2023.Research output: Contribution to conference › Poster › Communication
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Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons
Aldana, Blanca, Zhang, Y., Lihme, M. F., Bak, Lasse Kristoffer, Nielsen, Jørgen Erik, Holst, B., Hyttel, P., Freude, Kristine & Waagepetersen, Helle S., 2017, In: Neurochemistry International. 106, p. 48-61Research output: Contribution to journal › Journal article › Research › peer-review
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Chromatin organization, spatial localization of heterochromatin sequences and nucleolar activity, change towards final maturation in porcine oocytes
Bonnet-Garnier, A., Benc, M., Bartkova, A., Pihl, M., Chebrout, M., Strejcek, F., Hyttel, P., Lucas-Hahn, A., Laurincik, J., Freude, Kristine & Fenner, Merle Friederike, 2023. 1 p.Research output: Contribution to conference › Poster › Research › peer-review
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Co-expression network analysis to identify pluripotency biomarkers in bovine and porcine embryos
Mazzoni, G., Freude, Kristine, Hall, Vanessa Jane, Mashayekhi-Nezamabadi, K., Hyttel, P., Dinnyés, A. & Kadarmideen, H., 2015. 1 p.Research output: Contribution to conference › Poster › Research › peer-review
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Complexity of Sex Differences and Their Impact on Alzheimer’s Disease
Kadlecová, Marion, Freude, Kristine & Haukedal, H., 24 Apr 2023, In: Biomedicines. 11, 5, 29 p., 1261.Research output: Contribution to journal › Review › Research › peer-review
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Deciphering the naïve state of porcine iPSC
Freude, Kristine, Secher, Jan Bojsen-Møller, Mashayekhi-Nezamabadi, K., Petkov, S. G., Nielsen, T. T., Ceylan, A., Poligari, S., Dinnyes, A. & Hyttel, P., 18 Jun 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease
Tams, A. L. M., Sanz-Morello, B., Westi, Emil Winther, Mouhammad, Zaynab Ahmad, Andersen, Jens Velde, Freude, Kristine, Vohra, Rupali, Hannibal, Jens, Aldana, Blanca & Kolko, Miriam, 2022, In: Cellular and Molecular Neurobiology. 42, 1, p. 291–303Research output: Contribution to journal › Journal article › Research › peer-review
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Dementia, Brain Disorders and Molecular Mechanisms
Freude, Kristine & Krauss, S., 2019, In: Journal of Molecular Biology. 431, 9, p. 1709-1710Research output: Contribution to journal › Editorial › Research
ID: 38189431
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Induced pluripotent stem cells derived from Alzheimer's disease patients: the promise, the hope and the path ahead
Research output: Contribution to journal › Review › Research › peer-review
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462
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Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
Research output: Contribution to journal › Journal article › Research › peer-review
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334
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Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM)
Research output: Contribution to journal › Journal article › Research › peer-review
Published