Kristine Freude

Kristine Freude

Professor


  1. 2023
  2. Published

    The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression

    Corsi, G. I., Gadekar, V. P., Haukedal, H., Doncheva, Nadezhda Tsankova, Anthon, Christian, Ambardar, S., Palakodeti, D., Hyttel, P., Freude, Kristine, Seemann, Ernst Stefan & Gorodkin, Jan, 2023, In: Neurobiology of Disease. 178, 17 p., 105980.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2022
  4. Published

    Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease

    Tams, A. L. M., Sanz-Morello, B., Westi, Emil Winther, Mouhammad, Zaynab Ahmad, Andersen, Jens Velde, Freude, Kristine, Vohra, Rupali, Hannibal, Jens, Aldana, Blanca & Kolko, Miriam, 2022, In: Cellular and Molecular Neurobiology. 42, 1, p. 291–303

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Editorial: Metabolic Alterations in Neurodegenerative Disorders

    Freude, Kristine, Moreno-gonzalez, I., Rodriguez-ortiz, C. J. & Baglietto-vargas, D., 2022, In: Frontiers in Aging Neuroscience. 14, 3 p., 833109.

    Research output: Contribution to journalEditorialResearchpeer-review

  6. Published

    Fats, Friends or Foes: Investigating the Role of Short- and Medium-Chain Fatty Acids in Alzheimer’s Disease

    Ameen, Aisha, Freude, Kristine & Aldana, Blanca, 2022, In: Biomedicines. 10, 11, 2778.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published
  8. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    RhoA Signaling in Neurodegenerative Diseases

    Schmidt, S. I., Blaabjerg, M., Freude, Kristine & Meyer, M., 2022, In: Cells. 11, 9, 1520.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2021
  12. Published

    A protein-centric view of in vitro biological model systems for schizophrenia

    Chandrasekaran, Abinaya, Jensen, P., Mohamed, Fadumo Abdullahi, Lancaster, M., Benros, Michael Eriksen, Larsen, M. R. & Freude, Kristine, 2021, In: Stem Cells. 39, 12, p. 1569-1578

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    APOE4 affects basal and NMDAR mediated protein synthesis in neurons by perturbing calcium homeostasis

    Ramakrishna, S., Jhaveri, V., Konings, S. C., Nawalpuri, B., Chakraborty, S., Holst, B., Schmid, B., Gouras, G. K., Freude, Kristine & Muddashetty, R. S., 2021, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 41, 42, p. 8686-8709

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3

    Chandrasekaran, A., Dittlau, K. S., Corsi, G. I., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Zhang, Y., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J. E., Kolko, M., Kobolák, J., Dinnyés, A., Hyttel, P., Palakodeti, D. & 5 others, Gorodkin, Jan, Muddashetty, R. S., Meyer, M., Aldana, Blanca & Freude, Kristine, 2021, In: Stem Cell Reports. 16, 11, p. 2736-2751

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Cellular bioenergetics in human iPSC-derived glutamatergic neurons in health and disease

    Aldana, Blanca, Salcedo, C., Freude, Kristine & Waagepetersen, Helle S., 2021, Current Progress in iPSC-derived Cell Types. Birbrair, A. (ed.). Elsevier, p. 205-221 17 p. (Advances in Stem Cell Biology, Vol. 10).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, Helle S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Andersen, Jens Velde, Vinten, K. T., Pinborg, Lars Hageman, Waagepetersen, Helle S., Freude, Kristine & Aldana, Blanca, 2021, In: Frontiers in Aging Neuroscience. 13, 736580.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets

    Garcia Bermudez, Mariana Yolotzin, Freude, Kristine, Mouhammad, Zaynab Ahmad, van Wijngaarden, P., Martin, K. K. & Kolko, Miriam, 2021, In: Frontiers in Neurology. 12, 17 p., 624983.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, H., Westi, Emil Winther, Diaz-delCastillo, M., Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, Helle S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Implications of Glycosylation in Alzheimer’s Disease

    Haukedal, H. & Freude, Kristine, 2021, In: Frontiers in Neuroscience. 14, 18 p., 625348.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells

    Schmidt, S. I., Bogetofte, H., Ritter, L., Agergaard, Jette Bach, Hammerich, D., Kabiljagic, A. A., Wlodarczyk, A., Lopez, S. G., Sørensen, M. D., Jørgensen, M. L., Okarmus, J., Serrano, A. M., Kristensen, Bjarne Winther, Freude, Kristine, Owens, T. & Meyer, M., 2021, In: Stem Cell Reports. 16, p. 1-14

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Neural Derivates of Canine Induced Pluripotent Stem Cells-Like Cells From a Mild Cognitive Impairment Dog

    Chandrasekaran, Abinaya, Thomsen, B. B., Agerholm, Jørgen Steen, Pessôa, L. V. D. F., Godoy Pieri, N. C., Sabaghidarmiyan, V., Langley, K., Kolko, Miriam, De Andrade, A. F. C., Bressan, F. F., Hyttel, P., Berendt, Mette & Freude, Kristine, 2021, In: Frontiers in Veterinary Science. 8, 14 p., 725386.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Neuronal alpha-amylase is important for neuronal activity and glycogenolysis and reduces in presence of amyloid beta pathology

    Byman, E., Martinsson, I., Haukedal, H., Gouras, G., Freude, Kristine, Wennstrom, M. & Netherlands Brain Ban, N. B. B., 2021, In: Aging Cell. 20, 8, 14 p., 13433.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington’s Disease?

    Duque Villegas, Luisana Carolina, Nørremølle, Anne, Freude, Kristine & Vilhardt, Frederik, 2021, In: Frontiers in Aging Neuroscience. 13, 20 p., 736734.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders

    Frederiksen, Henriette Reventlow S, Doehn, U., Tveden-Nyborg, Pernille & Freude, Kristine, 2021, In: Frontiers in Genome Editing. 2, 623717.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Oxidative stress in optic neuropathies

    Sanz-Morello, B., Ahmadi, H., Vohra, Rupali, Saruhanian, S., Freude, Kristine, Hamann, Steffen & Kolko, Miriam, 2021, In: Antioxidants. 10, 10, 27 p., 1538.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    iPSC-derived Microglia for Disease Modeling of Frontotemporal Dementia 3

    Haukedal, H., Freude, Kristine, Garcia, B. A., Corsi, G., Gadekar, V. & Gorodkin, Jan, 2021, In: Glia. 69, S1, p. E480-E481 T14-066D.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  28. 2020
  29. Published

    Patient iPSC-Derived Neorons for Disease Modeling of Familiar Alzheimer's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, Oct 2020.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

ID: 38189431