Abinaya Chandrasekaran

Abinaya Chandrasekaran

Assistant Professor


Publication year:
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1 - 21 out of 21Page size: 50
  1. 2024
  2. Published

    Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy

    Kamand, M., Taleb, R., Wathikthinnakon, Methi, Mohamed, Fadumo Abdullahi, Ghanzanfari, S. P., Konstantinov, D., Hald, Jonas Laugård, Holst, B., Andersen, C. B., Møller, R. S., Lemke, J. R., Krey, I., Freude, Kristine & Chandrasekaran, Abinaya, 1 Apr 2024, In: Stem Cell Research. 76

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Charting the Explicit Path: Translational Dynamics of Hepatic Bioengineering from Experimental Benchmarks to Practical Bedside Applications

    Radhakrishnan, S., Martin, C. A., Dhayanithy, G., Martin, J. C., Chandrasekaran, Abinaya, Kalkura, S. N. & Rela, M., 2024, In: MedLiber of Regenerative Medicine. 2, 1, p. 1-18

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies

    Dittlau, Katarina Stoklund, Chandrasekaran, Abinaya, Freude, Kristine & Van Den Bosch, L., 2024, In: Bio-protocol. 14, 4, 16 p., e4936.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus

    Duque Villegas, Luisana Carolina, Chandrasekaran, Abinaya, Flintholm Andersen, S. A., Nørremølle, Anne, Schmid, B., Pouladi, M. A. & Freude, Kristine, 2024, In: Stem Cell Research. 77, 6 p., 103408.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2023
  7. Published

    Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3

    Haukedal, H., Syshøj Lorenzen, S., Westi, Emil Winther, Corsi, G., Gadekar, V. P., McQuade, A., Davtyan, H., Doncheva, Nadezhda Tsankova, Schmid, B., Chandrasekaran, Abinaya, Seemann, Ernst Stefan, Cirera, Susanna, Blurton-Jones, M., Meyer, M., Gorodkin, Jan, Aldana, Blanca & Freude, Kristine, 2023, In: Brain, Behavior, and Immunity. 113, p. 353-373

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology

    Rivera-Sánchez, P., Søndergaard, L., Wathikthinnakon, Methi, B. D. Magnusson, H., Frederiksen, Henriette Reventlow S, Aabæk Hammer, F., Taleb, R., Christian Cassidy, C., Tranholm Bruun, M., Tümer, Asuman Zeynep, Holst, B., Brasch-Andersen, C., Møller, R., Freude, Kristine & Chandrasekaran, Abinaya, 2023, In: Stem Cell Research. 71, 103193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Golgi fragmentation: One of the earliest organelle phenotypes in Alzheimer's disease neurons

    Haukedal, H., Corsi, G. I., Gadekar, V. P., Doncheva, N. T., Kedia, S., de Haan, N., Chandrasekaran, A., Jensen, P., Schiønning, P., Vallin, S., Marlet, F. R., Poon, A., Pires, C., Agha, F. K., Wandall, H. H., Cirera, S., Simonsen, A. H., Nielsen, T. T., Nielsen, J. E., Hyttel, P. & 7 others, Muddashetty, R., Aldana, Blanca, Gorodkin, Jan, Nair, D., Meyer, M., Larsen, M. R. & Freude, Kristine, 2023, In: Frontiers in Neuroscience. 17, 17 p., 1120086.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2021
  11. Published

    A protein-centric view of in vitro biological model systems for schizophrenia

    Chandrasekaran, Abinaya, Jensen, P., Mohamed, Fadumo Abdullahi, Lancaster, M., Benros, Michael Eriksen, Larsen, M. R. & Freude, Kristine, 2021, In: Stem Cells. 39, 12, p. 1569-1578

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3

    Chandrasekaran, A., Dittlau, K. S., Corsi, G. I., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Zhang, Y., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J. E., Kolko, M., Kobolák, J., Dinnyés, A., Hyttel, P., Palakodeti, D. & 5 others, Gorodkin, Jan, Muddashetty, R. S., Meyer, M., Aldana, Blanca & Freude, Kristine, 2021, In: Stem Cell Reports. 16, 11, p. 2736-2751

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Neural Derivates of Canine Induced Pluripotent Stem Cells-Like Cells From a Mild Cognitive Impairment Dog

    Chandrasekaran, Abinaya, Thomsen, B. B., Agerholm, Jørgen Steen, Pessôa, L. V. D. F., Godoy Pieri, N. C., Sabaghidarmiyan, V., Langley, K., Kolko, Miriam, De Andrade, A. F. C., Bressan, F. F., Hyttel, P., Berendt, Mette & Freude, Kristine, 2021, In: Frontiers in Veterinary Science. 8, 14 p., 725386.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2020
  15. Published

    Patient iPSC-Derived Neorons for Disease Modeling of Familiar Alzheimer's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, Oct 2020.

    Research output: Contribution to conference › Conference abstract for conference › Research

  16. Published

    Canine induced pluripotent stem cells: an in vitro approach to validate the dog as a large animal model for Alzheimer's disease

    Pessoa, L. V. D. F., Chandrasekaran, Abinaya, Thomsen, B. B., Berendt, Mette, Hyttel, P. & Freude, Kristine, Sep 2020, iPSCs from Diverse Species. 1 ed. Elsevier: Academic Press, Vol. 2.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  17. Published

    Canine induced pluripotent stem cells: An in vitro approach to validate the dog as a large animal model for Alzheimer’s disease

    De Figueiredo Pessôa, L. V., Chandrasekaran, Abinaya, Thomsen, B. B., Berendt, Mette, Hyttel, P. & Freude, Kristine, 2020, iPSCs from Diverse Species. Academic Press, p. 77-91 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  18. Published

    Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia

    Aldana, Blanca, Zhang, Y., Jensen, P., Chandrasekaran, Abinaya, Christensen, S. K., Nielsen, T. T., Nielsen, Jørgen Erik, Hyttel, P., Larsen, M. R., Waagepetersen, Helle S. & Freude, Kristine, 2020, In: Molecular Brain. 13, 1, 7 p., 125.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Mutation in FTD3 CHMP2B causes impaired autography and distorted energy metabolism cumulating in reactive astrocyte phenotypes

    Chandrasekaran, A., Dittlau, K. S., Corsi, G., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

    Research output: Contribution to conference › Conference abstract for conference › Research

  20. Published

    Mutations in FTD3 CHMP2B causes impaired autophagy and distorted energy metabolism cumulating in reactive astrocyte phenotypes

    Chandrasekaran, A., Dittlau, K. S., Corsi, G., Doncheva, N. T., Haukedal, H., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

    Research output: Contribution to conference › Poster › Research

  21. 2019
  22. Published

    Patient iPSC-Derived Neurons for Disease Modeling of Familiar Alzheier's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, 26 Mar 2019.

    Research output: Contribution to conference › Poster › Communication

  23. 2017
  24. Published

    Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation

    Ochalek, A., Mihalik, B., Avci, H. X., Chandrasekaran, Abinaya, Téglási, A., Bock, I., Giudice, M. L., Táncos, Z., Molnár, K., László, L., Nielsen, Jørgen Erik, Holst, B., Freude, Kristine, Hyttel, P., Kobolák, J. & Dinnyés, A., Dec 2017, In: Alzheimer's Research and Therapy. 9, 1, 19 p., 90.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism

    Chandrasekaran, Abinaya, 2017, In: Translational Psychiatry. 7 , 7, e1179.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

    Chandrasekaran, Abinaya, Avci, H., Ochalek, A., Rosingh, L., Molnar, K., Laszlo, L., Bellak, T., Teglasi, A., Pesti, K., Mike, A., Phanthong, P., Biro, O., Hall, Vanessa Jane, Kitiyanant, N., Krause, K., Kobolak, J. & Dinnyés, A., 2017, In: Stem Cell Research. 25, p. 139-151

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges

    Poon, A., Zhang, Y., Chandrasekaran, Abinaya, Phanthong, P., Schmid, B., Nielsen, T. T. & Freude, Kristine, 2017, In: New Biotechnology. 39, Part B, p. 190-198

    Research output: Contribution to journal › Review › Research › peer-review

ID: 172787827