Dan Arne Klærke

Dan Arne Klærke

Professor

Member of:


    1. 2023
    2. Published

      A molecular target of oxantel in whipworms

      Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Callø, Kirstine, Courtot, E., Grencis, R. K., Issouf, M., Martin, R., Neveu, C. & Charvet, C., 2023.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    3. Published

      NHA1 is a cation/proton antiporter essential for the water-conserving functions of the rectal complex in Tribolium castaneum.

      Naseem, Muhammad Tayyib, Beaven, R., Koyama, Takashi, Naz, S., Su, S., Leader, D. P., Klærke, Dan Arne, Callø, Kirstine, Denholm, B. & Halberg, Kenneth Veland, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 13, 11 p., e2217084120.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Xenobiotic Exposure and Migraine-Associated Signaling: A Multimethod Experimental Study Exploring Cellular Assays in Combination with Ex Vivo and In Vivo Mouse Models

      Rasmussen, Rikke Holm, Christensen, S. L., Callø, Kirstine, Nielsen, B. S., Rehfeld, A., Taylor-Clark, T. E., Haanes, Kristian Agmund, Taboureau, O., Audouze, K., Klærke, Dan Arne, Olesen, Jes & Kristensen, D. M., 2023, In: Environmental Health Perspectives. 131, 11, 14 p., 117003.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      pXOOY: A dual-function vector for expression of membrane proteins in Saccharomyces cerevisiae and Xenopus laevis oocytes

      Vold, Victoria Amstrup, Glanville, S., Klærke, Dan Arne & Pedersen, Per Amstrup, 2023, In: PLoS ONE. 18, 2, 16 p., e0281868.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. 2022
    7. Published

      Characterization of erenumab and rimegepant on calcitonin gene-related peptide induced responses in Xenopus Laevis oocytes expressing the calcitonin gene-related peptide receptor and the amylin-1 receptor

      La Cour, S. H., Juhler, K., Kogelman, L. J. A., Olesen, Jes, Klærke, Dan Arne, Kristensen, D. M. & Jansen-Olesen, I., 2022, In: Journal of Headache and Pain. 23, 12 p., 59.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      The Molecular target of oxantel in whipworms

      Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Callø, Kirstine, Courtot, E., Grencis, R., Issouf, M., Martin, R., Neveu, C. & Charvet, C., 2022.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    9. 2021
    10. Published

      Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins

      Preisler, Sarah Spruce, Wiuf, A. D., Friis, M., Kjaergaard, L., Hurd, M., Becares, E. R., Nurup, C. N., Bjoerkskov, F. B., Szathmáry, Z., Gourdon, Pontus Emanuel, Callø, Kirstine, Klærke, Dan Arne, Gotfryd, K. & Pedersen, Per Amstrup, 2021, In: Current research in structural biology. 3, p. 51-71 21 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Evaluation of electrocardiographic repolarization parameters after administration of trimethoprim-sulfadiazine, detomidine, or their combination in horses

      Trachsel, D. S., Callø, Kirstine, Jørgensen, Elin , Lunddahl, C. S., Pedersen, P. J., Kanters, Jørgen K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: American Journal of Veterinary Research. 82, 3, p. 207-217 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Exercise-Associated Sudden Death in Finnish Standardbred and Coldblooded Trotters - A Case Series With Pedigree Analysis

      Trachsel, D. S., Callø, Kirstine, Mykkänen, A. K., Raistakka, P., Anttila, M., Fredholm, Merete, Tala, M., Lamminpää, K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: Journal of Equine Veterinary Science. 104, 103694.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      The narrow-spectrum anthelmintic oxantel is a potent agonist of a novel acetylcholine receptor subtype in whipworms

      Hansen, Tina Vicky Alstrup, Cirera, Susanna, Neveu, C., Courtot, E., Charvet, C. L., Callø, Kirstine, Klærke, Dan Arne & Martin, R. J., 2021, In: P L o S Pathogens. 17, 2, 26 p., e1008982.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. 2020
    15. Published

      Cloning and Expression of an Oxantel Sensitive Homomeric Nicotinic Acetylcholine Receptor of Trichuris, the Tsu-ACR-16-like receptor

      Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Neveu, C., Callø, Kirstine & Martin, R., 2020.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    16. Published

      Purification and initial characterization of Plasmodium falciparum K+ channels, PfKch1 and PfKch2 produced in Saccharomyces cerevisiae

      Molbaek, K., Tejada, M., Ricke, C. H., Scharff-Poulsen, P., Ellekvist, P., Helix-Nielsen, C., Kumar, N., Klærke, Dan Arne & Pedersen, Per Amstrup, 2020, In: Microbial Cell Factories. 19, 1, 183.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. 2019
    18. Published

      PACAP-38 and PACAP(6-38) degranulate rat meningeal mast cells via the orphanMrgB3-receptor

      Pedersen, S. H., la Cour, S. H., Callø, Kirstine, Hauser, Frank, Olesen, Jes, Klærke, Dan Arne & Jansen-Olesen, I., Sep 2019, p. 4-4.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    19. Published

      Acquired LQTS in horses

      Callø, Kirstine, Trachsel, D. S., Rognant, Salomé, Friis, S., Pedersen, P. J. & Klærke, Dan Arne, 8 Aug 2019.

      Research output: Contribution to conferencePosterCommunication

    20. Published

      Cardiac repolarization in horses

      Klærke, Dan Arne, Trachsel, D. S., Buhl, Rikke, Pedersen, P. J. & Callø, Kirstine, 8 Aug 2019.

      Research output: Contribution to conferencePosterCommunication

    21. Published

      Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel K v 11.1

      Callø, Kirstine, Rognant, Salomé, Friis, S., Shaughnessy, C., Klærke, Dan Arne & Trachsel, D., 2019, In: Research in Veterinary Science. 123, p. 239-246 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      PACAP-38 and PACAP(6-38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB3-Receptor

      Pedersen, S. H., la Cour, S. H., Callø, Kirstine, Hauser, Frank, Olesen, Jes, Klærke, Dan Arne & Jansen-Olesen, I., 2019, In: Frontiers in Cellular Neuroscience. 13, 11 p., 114.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Purification of Functional Human TRP Channels Recombinantly Produced in Yeast

      Zhang, L., Wang, Kaituo, Klærke, Dan Arne, Callø, Kirstine, Lowrey, L., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2019, In: Cells. 8, 2, p. 1-20 148.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Structure of the human ClC-1 chloride channel

      Wang, Kaituo, Preisler, Sarah Spruce, Zhang, L., Cui, Y., Missel, Julie Winkel, Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. 2018
    26. Published

      Effects of trimethoprim–sulfadiazine and detomidine on the function of equine Kv11.1 channels in a two-electrode voltage-clamp (TEVC) oocyte model

      Trachsel, D. S., Tejada, M. A., Groesfjeld Christensen, V., Pedersen, P. J., Kanters, Jørgen K., Buhl, Rikke, Callø, Kirstine & Klærke, Dan Arne, 2018, In: Journal of Veterinary Pharmacology and Therapeutics. 41, 4, p. 536-545 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers

      Klærke, Dan Arne, Tejada, M. D. L. A., Christensen, V. G., Lassen, M., Pedersen, Per Amstrup & Callø, Kirstine, 2018, In: Current Protocols in Pharmacology. 81, 1, p. e37 17 p., e37.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. 2017
    29. Published

      Functional characterization of malaria parasites deficient in the K+ channel Kch2

      Ellekvist, P., Mlambo, G., Kumar, N. & Klærke, Dan Arne, Nov 2017, In: Biochemical and Biophysical Research Communications. 493, 1, p. 690-696 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Molecular cloning and functional expression of the K+ channel KV7.1 and the regulatory subunit KCNE1 from equine myocardium: [Inkl. corrigendum]

      Pedersen, P. J., Thomsen, K. B., Flak, J. B., Tejada, M. D. L. A., Hauser, Frank, Trachsel, D. S., Buhl, Rikke, Kalbfleisch, T., DePriest, M. S., MacLeod, J. N., Callø, Kirstine & Klærke, Dan Arne, Aug 2017, In: Research in Veterinary Science. 113, p. 79-86 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Heteromeric Slick/Slack K+ channels show graded sensitivity to cell volume changes

      Tejada, M. A., Hashem, N., Callø, Kirstine & Klærke, Dan Arne, 2017, In: PLOS ONE. 12, 2, 11 p., e0169914.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Single-Channel Recordings of K+ Channels Expressed in Saccharomyces Cerevisiae

      Tejada, M. D. L. A., Molbaek, K., Cazimi, H., Ellekvist, P., Callø, Kirstine, Nielsen, C. H., Pedersen, Per Amstrup & Klærke, Dan Arne, 2017, In: Biophysical Journal. 112, 3, Suppl. 1, p. 406A 1 p., 2002-Pos Board B322.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    33. 2016
    34. Published

      Differences in the electrocardiographic QT interval of various breeds of athletic horses during rest and exercise

      Pedersen, P. J., Karlsson, M., Madsen, M. F., Trachsel, D. S., Kanters, Jørgen K., Klærke, Dan Arne & Buhl, Rikke, 2016, In: Journal of Veterinary Cardiology. 18, 3, p. 255-264 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. 2015
    36. Published

      The Mutation P.T613a in the Pore Helix of the Kv 11.1 Potassium Channel is Associated with Long Qt Syndrome

      Poulsen, K. L., Hotait, M., Callø, Kirstine, Klærke, Dan Arne, Rebeiz, A., Nemer, G., Tejada, M. A. & Refaat, M. M., Nov 2015, In: Pacing and Clinical Electrophysiology. 38, 11, p. 1304–1309 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Action potential repolarization in equine hearts

      Callø, Kirstine, Pedersen, P. J., Tejada, M. D. L. A., Poulsen, K. L., Grubb, Søren, Buhl, Rikke & Klærke, Dan Arne, 2015, In: Biophysical Journal. 108, 2, Supplement 1, p. 113a 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    38. Published

      High yield purification of full-length functional hERG K+ channels produced in Saccharomyces cerevisiae

      Hansen, K. M., Scharff-Poulsen, P., Hélix-Nielsen, C., Klærke, Dan Arne & Pedersen, Per Amstrup, 2015, In: Microbial Cell Factories. 14, 16 p., 15.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Molecular cloning and functional expression of the Equine K+ channel KV11.1 (Ether à Go-Go-related/KCNH2 gene) and the regulatory subunit KCNE2 from equine myocardium

      Pedersen, P. J., Thomsen, K. B., Olander, E. R., Hauser, Frank, Tejada, M. D. L. A., Poulsen, K. L., Grubb, Søren, Buhl, Rikke, Callø, Kirstine & Klærke, Dan Arne, 2015, In: PloS one. 10, 9, 19 p., e0138320.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. 2014
    41. Published

      Cell volume changes regulate Slick (Slo2.1), but not Slack (Slo2.2) K+ channels

      Tejada, M. D. L. A., Stople, K., Bomholtz, Sofia Hammami, Meinild, A., Poulsen, A. N. & Klærke, Dan Arne, 2014, In: P L o S One. 9, 10, p. 1-8 8 p., e110833.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Diurnal modulation and sources of variation affecting ventricular repolarization in Warmblood horses

      Pedersen, P. J., Moeller, S. B., Madsen, M. F., Kanters, Jørgen K., Buhl, Rikke & Klærke, Dan Arne, 2014, In: Journal of Veterinary Cardiology. 16, 4, p. 265-276 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Expression of acute phase proteins and inflammatory cytokines in mouse mammary gland following Staphylococcus aureus challenge and in response to milk accumulation

      Nazemi, S., Aalbæk, Bent, Kjelgaard-Hansen, M., Safayi, S., Klærke, Dan Arne & Knight, C. H., 2014, In: Journal of Dairy Research. 81, 4, p. 445-454 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Expression of the Small Conductance Ca(2+)-Activated Potassium Channel Subtype 3 (SK3) in Rat Uterus after Stimulation with 17β-Estradiol

      Rahbek, M., Nazemi, S., Odum, L., Gupta, S., Poulsen, Steen Seier, Hay-Schmidt, Anders & Klærke, Dan Arne, 2014, In: PLOS ONE. 9, 2, p. 1-8 8 p., e87652.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Long-term effect on in vitro cloning efficiency after treatment of somatic cells with Xenopus egg extract in the pig

      Liu, Y., Østrup, O., Li, R., Li, J., Vajta, G., Kragh, P. M., Schmidt, M., Purup, S., Hyttel, P., Klærke, Dan Arne & Callesen, H., 2014, In: Reproduction, Fertility and Development. 26, 7, p. 1017-1031 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Reciprocity in the developmental regulation of aquaporins 1, 3 and 5 during pregnancy and lactation in the rat

      Nazemi, S., Rahbek, M., Parhamifar, L., Moghimi, S. M., Babamoradi, H., Mehrdana, Foojan, Klærke, Dan Arne & Knight, C. H., 2014, In: P L o S One. 9, 9, 7 p., e106809.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. 2013
    48. Published

      Erratum: Normal electrocardiographic QT interval in race-fit Standardbred horses at rest and its rate dependence during exercise (Journal of Veterinary Cardiology (2013) 15 (23-31))

      Pedersen, P. J., Kanters, Jørgen K., Buhl, Rikke & Klærke, Dan Arne, 1 Sep 2013, In: Journal of Veterinary Cardiology. 15, 3, 1 p.

      Research output: Contribution to journalComment/debateResearchpeer-review

    49. Published

      Normal electrocardiographic QT interval in race-fit Standardbred horses at rest and its rate dependence during exercise

      Pedersen, P. J., Kanters, Jørgen K., Buhl, Rikke & Klærke, Dan Arne, Mar 2013, In: Journal of Veterinary Cardiology. 15, 1, p. 23-31 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      In vivo studies of aquaporins 3 and 10 in human stratum corneum

      Jungersted, J., Bomholt, J., Bajraktari, N., Hansen, J. S., Klærke, Dan Arne, Pedersen, Per Amstrup, Hedfalk, K., Nielsen, K. H., Agner, T. & Hélix-Nielsen, C., 2013, In: Archives of Dermatological Research. 305, 8, p. 699-704 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Purinergic signalling - a possible mechanism for KCNQ1 channel response to cell volume challenges

      Bomholtz, Sofia Hammami, Willumsen, N. J., Meinild, A., Klærke, Dan Arne & Novak, Ivana, 2013, In: Acta Physiologica (Print). 207, 3, p. 503-515 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. 2012
    53. Published

      Clofilium inhibits slick and slack potassium channels

      Tejada, M. D. L. A., Stolpe, K., Meinild, A. K. & Klærke, Dan Arne, 12 Dec 2012, In: Biologics: Targets and Therapy. 6, p. 465-470 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      PHOSPHOINOSITIDES CONTROL THE ACTIVITY OF SLICK AND SLACK K+ CHANNELS

      Tejada, M. D. L. A., Jensen, Lars Jørn & Klærke, Dan Arne, Feb 2012.

      Research output: Contribution to conferencePosterResearchpeer-review

    55. Published

      PIP2 modulation of slick and slack K+ channels

      Tejada, M. D. L. A., Jensen, Lars Jørn & Klærke, Dan Arne, 2012, In: Biochemical and Biophysical Research Communications. 424, 2, p. 208-213 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. 2011
    57. Published

      Remodeling of ribosomal genes in somatic cells by Xenopus egg extract

      Østrup, O., Hyttel, P., Klærke, Dan Arne & Collas, P., 2011, In: Biochemical and Biophysical Research Communications. 412, 3, p. 487-493 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Submitted

      Upregulation of KCNQ1 currents by the KCNE1 beta subunit is not caused by insertion of KCNQ1 into the membrane

      Bomholtz, Sofia Hammami, Willumsen, N. & Klærke, Dan Arne, 2011, (Submitted). 1 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearch

    59. 2010
    60. Published

      KCNE1-induced increase in KCNQ1 currents is not mediated through enhanced membrane expression

      Bomholtz, Sofia Hammami, Willumsen, N. J. & Klærke, Dan Arne, Apr 2010, In: The FASEB Journal. 24, 610.6

      Research output: Contribution to journalConference abstract in journalResearch

    61. Published

      BKCa channels are expressed in the trigeminal ganglion and the trigeminal nucleus caudalis in rat

      Johansson, H. W., Hay-Schmidt, Anders, Poulsen, A. N., Klærke, Dan Arne, Olesen, J. & Jansen-Olesen, I., 2010, In: Cephalalgia. p. 1356 1 p.

      Research output: Contribution to journalConference abstract in journalResearch

    62. Published

      KCNQ1 channel response to cell volume changes is not mediated by ATP release

      Bomholtz, Sofia Hammami, Willumsen, N., Novak, Ivana & Klærke, Dan Arne, 2010, In: Acta Physiologica Scandinavica. Supplementum. 198, Suppl 677, p. 213 1 p.

      Research output: Contribution to journalConference abstract in journalResearch

    63. Published

      Localization of large conductance calcium-activated potassium channels and their effect on calcitonin gene-related peptide release in the rat trigemino-neuronal pathway

      Wulf-Johansson, H., Amrutkar, D. V., Hay-Schmidt, Anders, Poulsen, A. N., Klærke, Dan Arne, Olesen, J. & Jansen-Olesen, I., 2010, In: Neuroscience. 167, 4, p. 1091-1102 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    64. Published

      Mechanism for strict regulation of certain K+ channels by small, fast changes in cell volume

      Tejada, M. D. L. A., Stolpe, K., Bomholtz, Sofia Hammami, Willumsen, N. J., Poulsen, A. N. & Klærke, Dan Arne, 2010, In: Biophysical Journal. Supp. 1, p. 534a

      Research output: Contribution to journalConference abstract in journalResearch

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