Kirstine Callø
Associate Professor - Promotion Programme
Pathobiological Sciences
Grønnegårdsvej 7
1870 Frederiksberg C
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Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis
Axelsen, L. N., Callø, Kirstine, Braunstein, T. H., Riemann, Mads, Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, Kristine Boisen, Bartels, Emil Daniel, Baandrup, U., Jespersen, Thomas, Nielsen, L. B., von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.Research output: Contribution to journal › Journal article › Research › peer-review
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Managing the complexity of communication: regulation of gap junctions by post-translational modification
Axelsen, L. N., Callø, Kirstine, von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, Oct 2013, In: Frontiers in Pharmacology. 4, p. 1-18 18 p., 130.Research output: Contribution to journal › Journal article › Research › peer-review
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The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels.
Bentzen, Bo Hjorth, Nardi, A., Callø, Kirstine, Madsen, L. S., Olesen, Søren-Peter & Grunnet, Morten, 2007, In: Molecular Pharmacology. 72, 4, p. 1033-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels.
Bentzen, Bo Hjorth, Schmitt, Nicole, Callø, Kirstine, Dalby Brown, W., Grunnet, Morten & Olesen, Søren-Peter, 2006, In: Neuropharmacology. 51, 6, p. 1068-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A simple and scalable 3D printing methodology for generating aligned and extended human and murine skeletal muscle tissues
Cakal, S. D., Radeke, C., Alcala, J. F., Ellman, D. G., Butdayev, S., Andersen, D. C., Callø, Kirstine & Lind, J. U., 2022, In: Biomedical Materials (Bristol). 17, 4Research output: Contribution to journal › Journal article › Research › peer-review
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Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Nav1.5 gain-of-function mutation (G213D)
Callø, Kirstine, Broendberg, A. K., Christensen, A. H., Pedersen, L. N., Olesen, Morten Steen Salling, de Los Angeles Tejada, M., Friis, S., Thomsen, Morten Bækgaard, Bundgård, Henning & Jensen, H. K., 15 Apr 2018, In: International Journal of Cardiology. 257, p. 160-167 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A
Calloe, K., Schmitt, Nicole, Grubb, Søren, Pfeiffer, R., David, J., Kanter, R., Cordeiro, J. M., Antzelevitch, C. & Callø, Kirstine, 2011, In: Canadian Journal of Physiology and Pharmacology. 89, 10, p. 723-36 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome
Callø, Kirstine, Cordeiro, J. M., Di Diego, J. M., Hansen, R. S., Grunnet, Morten, Olesen, Søren-Peter & Antzelevitch, C., 2008, In: Cardiovascular Research. 81, 4, p. 686-94 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interventricular differences in sodium current and its potential role in Brugada syndrome
Callø, Kirstine, Aistrup, G. L., Di Diego, J. M., Goodrow, R. J., Treat, J. A. & Cordeiro, J. M., 2018, In: Physiological Reports. 6, 14, 12 p., e13787.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle
Callø, Kirstine, Soltysinska, E., Jespersen, Thomas, Lundby, Alicia, Antzelevitch, C., Olesen, Søren-Peter & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multifocal ectopic purkinje-related premature contractions and related cardiomyopathy
Callø, Kirstine, Magnusson, H. B. D., Lildballe, D. L., Christiansen, M. K. & Jensen, H. K., 2023, In: Frontiers in Cardiovascular Medicine. 10, 1179018.Research output: Contribution to journal › Review › Research › peer-review
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Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel K v 11.1
Callø, Kirstine, Rognant, Salomé, Friis, S., Shaughnessy, C., Klærke, Dan Arne & Trachsel, D., 2019, In: Research in Veterinary Science. 123, p. 239-246 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes.
Callø, Kirstine, Nielsen, Morten Schak, Grunnet, Morten, Schmitt, Nicole & Jorgensen, N. K., 2007, In: BBA General Subjects. 1773, 6, p. 764-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.
Callø, Kirstine, Elmedyb, P., Olesen, Søren-Peter, Jorgensen, N. K. & Grunnet, Morten, 2005, In: Biophysical Journal. 89, 3, p. 2159-69 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The loss-of-function variant p.M764R in the cardiac sodium channel Nav1.5 is associated with ventricular arrhythmias and sudden cardiac death in a family without overt Brugada syndrome
Callø, Kirstine, Christiansen, M. K., Henriksen, F. L. & Jensen, H. K., Feb 2024, In: HeartRhythm Case Reports. 10, 2, p. 137-141 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A dual potassium channel activator improves repolarization reserve and normalizes ventricular action potentials
Callø, Kirstine, Di Diego, J. M., Hansen, R. S., Nagle, S. A., Treat, J. A. & Cordeiro, J. M., 19 Mar 2016, In: Biochemical Pharmacology. 108, p. 36-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Doctoral Dissertation: The transient outward potassium current in healthy and diseased hearts
Callø, Kirstine, Jan 2019, In: Acta Physiologica. 225 , S717, e13225.Research output: Contribution to journal › Journal article › Research › peer-review
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The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes
Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027Research output: Contribution to journal › Journal article › Research › peer-review
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Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.
Callø, Kirstine, Ravn, L. S., Schmitt, Nicole, Sui, J. L., Duno, M., Haunso, S., Grunnet, Morten, Svendsen, J. H. & Olesen, Søren-Peter, 2007, In: Biochemical and Biophysical Research Communications. 364, 4, p. 889-95 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.
Callø, Kirstine, Nof, E., Jespersen, Thomas, Di Diego, J. M., Chlus, N., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Transient Outward Potassium Current in Healthy and Diseased Hearts
Callø, Kirstine, 2019, Københavns Universitet.Research output: Book/Report › Doctoral thesis › Research
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Tissue-specific effects of acetylcholine in the canine heart
Callø, Kirstine, Goodrow, R., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2013, In: A J P: Heart and Circulatory Physiology (Online). 305, p. H66-H75 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Action potential repolarization in equine hearts
Callø, Kirstine, Pedersen, P. J., Tejada, M. D. L. A., Poulsen, K. L., Grubb, Søren, Buhl, Rikke & Klærke, Dan Arne, 2015, In: Biophysical Journal. 108, 2, Supplement 1, p. 113a 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Acquired LQTS in horses
Callø, Kirstine, Trachsel, D. S., Rognant, Salomé, Friis, S., Pedersen, P. J. & Klærke, Dan Arne, 8 Aug 2019.Research output: Contribution to conference › Poster › Communication
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Characterization and mechanisms of action of novel NaV1.5 channel mutations associated with Brugada syndrome
Callø, Kirstine, Refaat, M. M., Grubb, Søren, Wojciak, J., Campagna, J., Thomsen, N. M., Nussbaum, R. L., Scheinman, M. M. & Schmitt, Nicole, 2013, In: Circulation. Arrhythmia and Electrophysiology (Online). 6, 1, p. 177-184 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome
Cordeiro, J. M., Marieb, M., Pfeiffer, R., Callø, Kirstine, Burashnikov, E. & Antzelevitch, C., 2009, In: Journal of Molecular and Cellular Cardiology. 46, 5, p. 695-703 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological consequences of transient outward K(+) current activation during heart failure in the canine left ventricle
Cordeiro, J. M., Callø, Kirstine, Moise, N. S., Kornreich, B., Giannandrea, D., Di Diego, J. M., Olesen, Søren-Peter & Antzelevitch, C., 2012, In: Journal of Molecular and Cellular Cardiology. 52, 6, p. 1291-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological roles of the transient outward current Ito in normal and diseased hearts
Cordeiro, J. M., Callø, Kirstine, Aschar-Sobbi, R., Kim, K., Korogyi, A., Occhipinti, D., Backx, P. H. & Panama, B. K., 1 Jan 2016, In: Frontiers in bioscience (Scholar edition). 8, p. 143-159 17 p., 454.Research output: Contribution to journal › Journal article › Research › peer-review
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Gliadin Fragments and a Specific Gliadin 33-mer Peptide Close KATP Channels and Induce Insulin Secretion in INS-1E Cells and Rat Islets of Langerhans
Dall, M., Callø, Kirstine, Haupt-Jorgensen, M., Larsen, J., Schmitt, Nicole, Josefsen, K. & Buschard, K., 2013, In: PLOS ONE. 8, 6, p. 1-10 10 p., e66474.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional properties of human neuronal Kv11 channels
Einarsen, K., Callø, Kirstine, Grunnet, Morten, Olesen, Søren-Peter & Schmitt, Nicole, 2009, In: Pflügers Archiv: European Journal of Physiology. 458, 4, p. 689-700 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intramural Purkinje fibers facilitate rapid ventricular activation in the equine heart
Elbrønd (Bibs), Vibeke Sødring, Thomsen, Morten Bækgaard, Isaksen, Jonas L., Lunde, E. D., Vincenti, S., Wang, T., Tranum-Jensen, Jørgen & Callø, Kirstine, 2023, In: Acta Physiologica. 237, 3, e13925.Research output: Contribution to journal › Journal article › Research › peer-review
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Modulation of ERG channels by XE991.
Elmedyb, P., Callø, Kirstine, Schmitt, Nicole, Hansen, R. S., Grunnet, Morten & Olesen, Søren-Peter, 2007, In: Basic & Clinical Pharmacology & Toxicology. 100, 5, p. 316-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Challenges in Establishing Animal Induced Pluripotent Stem Cells
Enevoldsen, Sara, Magnusson, H. B. D., Lind, J. U., Freude, Kristine & Callø, Kirstine, 15 Sep 2023.Research output: Contribution to conference › Poster › Communication
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Takotsubo cardiomyopathy and Brugada syndrome in a patient with a novel loss-of-function variant in the cardiac sodium channel Nav1.5
Frederiksen, T. C., Callø, Kirstine, Geryk, M. & Jensen, H. K., 2022, In: HeartRhythm Case Reports. 8, 5, p. 325-329Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure
Grubb, Søren, Callø, Kirstine & Thomsen, Morten Bækgaard, 2012, In: Frontiers in Physiology. 3, p. 118Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of cultured human cardiomyocyte clusters obtained from embryos/fetuses or derived from human embryonic stem cells
Grubb, Søren, Vestergaard, M. L., Andersen, A. S., Rasmussen, K. K., Mamsen, L., Tuckute, G., Grunnet-Lauridsen, K., Møllgård, Kjeld, Ernst, E., Christensen, Søren Tvorup, Callø, Kirstine & tcg964, tcg964, 2019, In: Stem Cells and Development. 28, 9, p. 608-619Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of K+ currents in heart failure is accentuated in KChIP2 deficient mice
Grubb, Søren, Speerschneider, T., Occhipinti, D., Fiset, C., Olesen, Søren-Peter, Thomsen, Morten Bækgaard & Callø, Kirstine, 2014, In: Journal of Cardiovascular Electrophysiology. 25, 8, p. 896-904 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2
Grubb, Søren, Aistrup, G. L., Koivumäki, J. T., Speerschneider, T., Gottlieb, Lisa Amalie, Mutsaers, N. A. M., Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H481-H489 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome.
Grunnet, Morten, Behr, E. R., Callø, Kirstine, Hofman-Bang, J., Till, J., Christiansen, M., McKenna, W. J., Olesen, Søren-Peter & Schmitt, Nicole, 2005, In: Heart Rhythm. 2, 11, p. 1238-49 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels
Hansen, D. B., Ye, Z., Callø, Kirstine, Braunstein, T. H., Hofgaard, J. P., Ransom, B. R., Nielsen, Morten Schak & MacAulay, Nanna, 19 Sep 2014, In: The Journal of Biological Chemistry. 289, 38, p. 26058-73 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The narrow-spectrum anthelmintic oxantel is a potent agonist of a novel acetylcholine receptor subtype in whipworms
Hansen, Tina Vicky Alstrup, Cirera, Susanna, Neveu, C., Courtot, E., Charvet, C. L., Callø, Kirstine, Klærke, Dan Arne & Martin, R. J., 2021, In: P L o S Pathogens. 17, 2, 26 p., e1008982.Research output: Contribution to journal › Journal article › Research › peer-review
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The Molecular target of oxantel in whipworms
Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Callø, Kirstine, Courtot, E., Grencis, R., Issouf, M., Martin, R., Neveu, C. & Charvet, C., 2022.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Cloning and Expression of an Oxantel Sensitive Homomeric Nicotinic Acetylcholine Receptor of Trichuris, the Tsu-ACR-16-like receptor
Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Neveu, C., Callø, Kirstine & Martin, R., 2020.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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A molecular target of oxantel in whipworms
Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Callø, Kirstine, Courtot, E., Grencis, R. K., Issouf, M., Martin, R., Neveu, C. & Charvet, C., 2023.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease
Holst, A. G., Callø, Kirstine, Jespersen, Thomas, Cedergreen, P., Winkel, B. G., Jensen, H. K., Leren, T. P., Haunso, S., Svendsen, Jesper Hastrup & Tfelt-Hansen, J., 2009, In: Case Reports in Medicine. 2009, p. 963645Research output: Contribution to journal › Journal article › Research › peer-review
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The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.
Jensen, H. S., Callø, Kirstine, Jespersen, Thomas, Jensen, B. S. & Olesen, Søren-Peter, 2005, In: Brain Research. 139, 1, p. 52-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstitution and Electrophysiological Characterization of Ion Channels in Lipid Bilayers
Klærke, Dan Arne, Tejada, M. D. L. A., Christensen, V. G., Lassen, M., Pedersen, Per Amstrup & Callø, Kirstine, 2018, In: Current Protocols in Pharmacology. 81, 1, p. e37 17 p., e37.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiac repolarization in horses
Klærke, Dan Arne, Trachsel, D. S., Buhl, Rikke, Pedersen, P. J. & Callø, Kirstine, 8 Aug 2019.Research output: Contribution to conference › Poster › Communication
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Quantitative proteome comparison of human hearts with those of model organisms
Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.Research output: Contribution to journal › Journal article › Research › peer-review
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The Nav1.5 variant G213D found in patients with MEPPC is associated with increased window current and gating pore current
Magnusson, H. B. D., Geryk, M., Cordeiro, J. M., Lind, J. U., Jensen, H. K., Freude, Kristine & Callø, Kirstine, 16 Sep 2023.Research output: Contribution to conference › Poster › Communication
ID: 5330
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Dysfunction of the heteromeric KV7.3/KV7.5 potassium channel is associated with autism spectrum disorders
Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization and mechanisms of action of novel NaV1.5 channel mutations associated with Brugada syndrome
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Tissue-specific effects of acetylcholine in the canine heart
Research output: Contribution to journal › Journal article › Research › peer-review
Published