Kristine Freude

Kristine Freude

Professor


Publication year:
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51 - 100 out of 114Page size: 50
  1. 2020
  2. Published

    Canine induced pluripotent stem cells: An in vitro approach to validate the dog as a large animal model for Alzheimer’s disease

    De Figueiredo Pessôa, L. V., Chandrasekaran, Abinaya, Thomsen, B. B., Berendt, Mette, Hyttel, P. & Freude, Kristine, 2020, iPSCs from Diverse Species. Academic Press, p. 77-91 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  3. Published

    Enrichment of retinal ganglion and Müller glia progenitors from retinal organoids derived from human induced pluripotent stem cells - possibilities and current limitations

    Freude, Kristine, Saruhanian, S., Mccauley, A., Paterson, C., Odette, M., Oostenink, A., Hyttel, P., Gillies, M., Haukedal, H. & Kolko, Miriam, 2020, In: World Journal of Stem Cells. 12, 10, p. 1171-1183

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Patient iPSC-Derived Neorons for Disease Modeling of Familiar Alzheimer's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, Oct 2020.

    Research output: Contribution to conference › Conference abstract for conference › Research

  5. Published

    Generation of neural progenitor cells (NPC) from porcine induced pluripotent stem cells (piPSC)

    Machado, L. S., Pieri, N. C. G., Botigelli, R. C., de Castro, R. V. G., de Souza, A. F., Bridi, A., Lima, M. A., Fantinato Neto, P., de Figueiredo Pessôa, L. V., Martins, S. M. M. K., de Andrade, A. F. C., Freude, Kristine & Bressan, F. F., 2020, In: Journal of Tissue Engineering and Regenerative Medicine. 14, 12, p. 1880-1891

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Human induced pluripotent cells in personalized treatment of monogenic epilepsies

    Mohammad, N. A., Freude, Kristine, Haukedal, H., Tümer, Asuman Zeynep & Møller, R. S., 2020, In: Journal of Translational Genetics and Genomics. 2020, 4, p. 238-250

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Canine induced pluripotent stem cells: an in vitro approach to validate the dog as a large animal model for Alzheimer's disease

    Pessoa, L. V. D. F., Chandrasekaran, Abinaya, Thomsen, B. B., Berendt, Mette, Hyttel, P. & Freude, Kristine, Sep 2020, iPSCs from Diverse Species. 1 ed. Elsevier: Academic Press, Vol. 2.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  8. 2019
  9. Published

    Cell type specific expression of toll-like receptors in human brains and implications in Alzheimer's disease

    Frederiksen, Henriette Reventlow S, Haukedal, H. & Freude, Kristine, 2019, In: BioMed Research International. 2019, 18 p., 7420189.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene

    Frederiksen, Henriette Reventlow S, Holst, B., Ramakrishna, S., Muddashetty, R., Schmid, B. & Freude, Kristine, 1 Jan 2019, In: Stem Cell Research. 34, 5 p., 101368.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene.

    Frederiksen, Henriette Reventlow S, Holst, B., Mau-Holzmann, U. A., Freude, Kristine & Schmid, B., Mar 2019, In: Stem Cell Research. 35, 4 p., 101403.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Dementia, Brain Disorders and Molecular Mechanisms

    Freude, Kristine & Krauss, S., 2019, In: Journal of Molecular Biology. 431, 9, p. 1709-1710

    Research output: Contribution to journal › Editorial › Research

  13. Published

    Metabolic impairments in neurons and astrocytes derived from human induced pluripotent stem cells of Alzheimer's disease patients

    Garcia, B. A., Salcedo, C., Hyttel, P., Waagepetersen, Helle S. & Freude, Kristine, 2019, p. 111-111.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  14. Published

    Implications of Microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

    Haukedal, H. & Freude, Kristine, 2019, In: Journal of Molecular Biology. 431, 9, p. 1818-1829

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Patient iPSC-Derived Neurons for Disease Modeling of Familiar Alzheier's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, 26 Mar 2019.

    Research output: Contribution to conference › Poster › Communication

  16. Published

    Oocytes, embryos and pluripotent stem cells from a biomedical perspective

    Hyttel, P., Pessôa, L. V. D. F., Secher, Jan Bojsen-Møller, Dittlau, Katarina Stoklund, Freude, Kristine, Hall, Vanessa Jane, Fair, T., Assey, R. J., Laurincik, J., Callesen, H., Greve, T. & Stroebech, L. B., 2019, In: Animal Reproduction. 16, 3, p. 508-523 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells

    Kobolák, J., Molnár, K., Varga, E., Bock, I., Jezsó, B., Téglási, A., Zhou, S., Lo Giudice, M., Hoogeveen-Westerveld, M., Pijnappel, W. P., Phanthong, P., Varga, N., Kitiyanant, N., Freude, Kristine, Nakanishi, H., László, L., Hyttel, P. & Dinnyés, A., 2019, In: Experimental Cell Research. 380, 2, p. 216-233 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Genetic protection modifications: Moving beyond the binary distinction between therapy and enhancement for human genome editing

    Mikkelsen, R. C. B., Frederiksen, Henriette Reventlow S, Gjerris, Mickey, Holst, B., Hyttel, P., Luo, Y., Freude, Kristine & Sandøe, Peter, 2019, In: CRISPR Journal. 2, 6, p. 362-369 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Induced pluripotent stem cells throughout the animal kingdom: Availability and applications

    Pessôa, L. V. D. F., Bressan, F. F. & Freude, Kristine, 2019, In: World Journal of Stem Cells. 11, 8, p. 491-505 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. 2018
  21. Published

    Mammalian embryo comparison identifies novel pluripotency genes associated with the naive or primed state

    Bernardo, A. S., Jouneau, A., Marks, H., Kensche, P., Kobolak, J., Freude, K., Hall, V., Feher, A., Polgar, Z., Sartori, C., Bock, I., Louet, C., Faial, T., Kerstens, H. H. D., Bouissou, C., Parsonage, G., Mashayekhi, K., Smith, J. C., Lazzari, G., Hyttel, P. & 4 others, Stunnenberg, H. G., Huynen, M., Pedersen, R. A. & Dinnyes, A., 2018, In: Biology Open. 7, 8, 17 p., bio033282.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Generation of transgene-free porcine intermediate type induced pluripotent stem cells

    Li, D., Secher, Jan Bojsen-Møller, Hyttel, P., Ivask, M., Kolko, Miriam, Hall, Vanessa Jane & Freude, Kristine, 2018, In: Cell Cycle. 17, 23, p. 2547-2563 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA.

    Pan, X., Xiong, K., Anthon, Christian, Hyttel, P., Freude, Kristine, Jensen, Lars Juhl & Gorodkin, Jan, 6 Nov 2018, In: Genes. 9, 11, 11 p., 536.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Essential Roles of Lactate in Müller Cell Survival and Function

    Vohra, Rupali, Aldana, Blanca, Jensen, Dorte Skytt, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Dec 2018, In: Molecular Neurobiology. 55, 12, p. 9108-9121 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Muller cell survival and function is maintained by the presence of lactate

    Vohra, Rupali, Skytt, D. M., Aldana, Blanca, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, Jul 2018, p. 1480. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  26. 2017
  27. Published

    Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons

    Aldana, Blanca, Zhang, Y., Lihme, M. F., Bak, Lasse Kristoffer, Nielsen, Jørgen Erik, Holst, B., Hyttel, P., Freude, Kristine & Waagepetersen, Helle S., 2017, In: Neurochemistry International. 106, p. 48-61

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts

    Li, D., Secher, Jan Bojsen-Møller, Juhl, M., Mashayekhi-Nezamabadi, K., Nielsen, T. T., Holst, B., Hyttel, P., Freude, Kristine & Hall, Vanessa Jane, 2017, In: Cell Cycle. 16, 11, p. 1070-1084

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Identification of potential biomarkers in donor cows for in vitro embryo production by granulosa cell transcriptomics

    Mazzoni, G., Salleh, S. M., Freude, Kristine, Pedersen, H. S., Stroebech, L., Callesen, H., Hyttel, P. & Kadarmideen, H. N., 2017, In: PLOS ONE. 12, 4, 27 p., e0175464.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence

    Mazzoni, G., Razza, E., Pedersen, H. S., Secher, Jan Bojsen-Møller, Kadarmideen, H. N., Callesen, H., Stroebech, L., Freude, Kristine & Hyttel, P., 2017, In: Animal Reproduction. 14, 3, p. 482-489 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation

    Ochalek, A., Mihalik, B., Avci, H. X., Chandrasekaran, Abinaya, Téglási, A., Bock, I., Giudice, M. L., Táncos, Z., Molnár, K., László, L., Nielsen, Jørgen Erik, Holst, B., Freude, Kristine, Hyttel, P., Kobolák, J. & Dinnyés, A., Dec 2017, In: Alzheimer's Research and Therapy. 9, 1, 19 p., 90.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Toward Development of Pluripotent Porcine Stem Cells by Road Mapping Early Embryonic Development

    Petkov, S., Freude, Kristine, Mashayekhi-Nezamabadi, K., Hyttel, P. & Hall, Vanessa Jane, Mar 2017, Animal Models and Human Reproduction: Cell and Molecular Approaches with Reference to Human Reproduction. Schatten, H. & Constantinescu, G. M. (eds.). Wiley-Blackwell, p. 485-508 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  33. Published

    Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges

    Poon, A., Zhang, Y., Chandrasekaran, Abinaya, Phanthong, P., Schmid, B., Nielsen, T. T. & Freude, Kristine, 2017, In: New Biotechnology. 39, Part B, p. 190-198

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals

    Secher, Jan Bojsen-Møller, Liu, Y., Petkov, S. G., Li, D., Hall, Vanessa Jane, Schmidt, M., Callesen, H., Freude, Kristine & Hyttel, P., 2017, In: Animal Reproduction Science. 178, p. 40-49

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells

    Secher, J. O. B., Ceylan, A., Mazzoni, G., Mashayekhi-Nezamabadi, K., Li, T., Muenthaisong, S., Nielsen, T., Li, D., Li, S., Petkov, S. G., Cirera Salicio, S., Luo, Y., Thombs, L., Kadarmideen, H., Dinnyés, A., Bolund, L., Roelen, B. A., Schmidt, M., Callesen, H., Hyttel, P. & 1 others, Freude, Kristine, 2017, In: Molecular Reproduction and Development. 84, 3, p. 229-245

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts

    Xiong, K., Zhou, Y., Blichfeld, K. A., Hyttel, P., Bolund, L., Freude, Kristine & Luo, Y., Jun 2017, In: Cellular Reprogramming. 19, 3, p. 189-198 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Mitochondrial Spare Respiratory Capacity Is Negatively Correlated with Nuclear Reprogramming Efficiency

    Yan, Z., Al-Saaidi, R. A., Fernandez Guerra, P., Freude, Kristine, Olsen, R. K. J., Jensen, U. B., Gregersen, N., Hyttel, P., Bolund, L., Aagaard, L., Bross, P. & Luo, Y., 2017, In: Stem Cells and Development. 26, 3, p. 166-176

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B

    Zhang, Y., Schmid, B., Qas Younan, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA. & 4 others, Holst, B., Clausen, C., Hyttel, P. & Freude, Kristine, 2017, In: Stem Cell Reports. 8, 3, p. 648-658

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2016
  40. Published

    Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a M146I mutation in PSEN1

    Li, T., Pires, C., Nielsen, T. T., Waldemar, Gunhild, Hjermind, L. E., Nielsen, Jørgen Erik, Dinnyes, A., Holst, B., Hyttel, P. & Freude, Kristine, Mar 2016, In: Stem Cell Research. 16, 2, p. 334-337 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying an A79V mutation in PSEN1

    Li, T., Pires, C., Nielsen, T. T., Waldemar, Gunhild, Hjermind, L. E., Nielsen, Jørgen Erik, Dinnyes, A., Hyttel, P. & Freude, Kristine, Mar 2016, In: Stem Cell Research. 16, 2, p. 229-332 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Systems Biology and Stem Cell Pluripotency: Revisiting the Discovery of Induced Pluripotent Stem Cell

    Mashayekhi, K., Hall, Vanessa Jane, Freude, Kristine, Høffding, M. K., Labusca, L. & Hyttel, P., 29 Oct 2016, Systems Biology in Animal Production and Health. Kadarmideen, H. N. (ed.). 1 ed. Springer, Vol. 2. p. 127-154 28 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  43. Published

    Human Induced Pluripotent stem cells and their derivatives for disease modeling and therapeutic applications in Alzheimer's disease

    Pires, C., Hall, Vanessa Jane & Freude, Kristine, 20 May 2016, Alzheimer's disease. SMGroup, p. 1-25 25 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  44. Published

    Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1

    Pires, C., Schmid, B., Petræus, C., Poon, A. F., Nimsanor, N., Nielsen, T. T., Waldemar, Gunhild, Hjermind, L. E., Nielsen, Jørgen Erik, Hyttel, P. & Freude, Kristine, Sep 2016, In: Stem Cell Research. 17, 2, p. 285-288 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1

    Poon, A. F., Li, T., Pires, C., Nielsen, T. T., Nielsen, Jørgen Erik, Holst, B., Dinnyes, A., Hyttel, P. & Freude, Kristine, Nov 2016, In: Stem Cell Research. 17, 3, p. 470-473 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Generation of a gene-corrected isogenic control hiPSC line derived from a familial Alzheimer's disease patient carrying a L150P mutation in presenilin 1

    Poon, A. F., Schmid, B., Pires, C., Nielsen, T. T., Hjermind, L. E., Nielsen, Jørgen Erik, Holst, B., Hyttel, P. & Freude, Kristine, Nov 2016, In: Stem Cell Research. 17, 3, p. 466-469 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Initial embryology and pluripotent stem cells in the pig: the quest for establishing the pig as a model for cell therapy

    Secher, Jan Bojsen-Møller, Callesen, H., Freude, Kristine & Hyttel, P., 1 Jan 2016, In: Theriogenology. 85, 1, p. 162-171 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1

    Tubsuwan, A., Pires, C., Rasmussen, M. A., Schmid, B., Nielsen, Jørgen Erik, Hjermind, L. E., Hall, Vanessa Jane, Nielsen, T. T., Waldemar, Gunhild, Hyttel, P., Clausen, C., Kitiyanant, N., Freude, Kristine & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 110-112 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM)

    Xiong, K., Zhou, Y., Hyttel, P., Bolund, L., Freude, Kristine & Luo, Y., Nov 2016, In: Stem Cell Research. 17, 3, p. 665-669 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B

    Zhang, Y., Schmid, B., Nielsen, T. T., Nielsen, Jørgen Erik, Clausen, C., Hyttel, P., Holst, B. & Freude, Kristine, Jul 2016, In: Stem Cell Research. 17, 1, p. 148-150 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B

    Zhang, Y., Schmid, B., Nielsen, T. T., Nielsen, Jørgen Erik, Clausen, C., Hyttel, P., Holst, B. & Freude, Kristine, 2016, In: Stem Cell Research. 17, 1, p. 151-153 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Neurosphere based differentiation of human iPSC improves astrocyte differentiation

    Zhou, S., Szczesna, K., Ochalek, A., Kobolák, J., Varga, E., Nemes, C., Chandrasekaran, A., Rasmussen, M., Cirera, Susanna, Hyttel, P., Dinnyés, A., Freude, Kristine & Avci, H. X., 2016, In: Stem Cells International. 2016, 15 p., 4937689.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    The positional identity of iPSC-derived neural progenitor cells along the anterior-posterior axis is controlled in a dosage-dependent manner by bFGF and EGF

    Zhou, S., Ochalek, A., Szczesna, K., Avci, H. X., Kobolak, J., Varga, E., Rasmussen, M., Holst, B., Cirera, Susanna, Hyttel, P., Freude, Kristine & Dinnyes, A., Oct 2016, In: Differentiation. 92, 4, p. 183-194 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2015
  55. Published

    Co-expression network analysis to identify pluripotency biomarkers in bovine and porcine embryos

    Mazzoni, G., Freude, Kristine, Hall, Vanessa Jane, Mashayekhi-Nezamabadi, K., Hyttel, P., Dinnyés, A. & Kadarmideen, H., 2015. 1 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  56. Published

    Optimization of three-dimensional imaging on in vitro produced porcine blastocysts and chimeras for stem cell testing: a technology report.

    Secher, Jan Bojsen-Møller, Freude, Kristine, Li, R. & Callesen, H., 2015, In: Stem Cells and Development. 24, 9, p. 1141-1145 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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