Kristine Freude

Kristine Freude

Professor


  1. Published

    The positional identity of iPSC-derived neural progenitor cells along the anterior-posterior axis is controlled in a dosage-dependent manner by bFGF and EGF

    Zhou, S., Ochalek, A., Szczesna, K., Avci, H. X., Kobolak, J., Varga, E., Rasmussen, M., Holst, B., Cirera, Susanna, Hyttel, P., Freude, Kristine & Dinnyes, A., Oct 2016, In: Differentiation. 92, 4, p. 183-194 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Neurosphere based differentiation of human iPSC improves astrocyte differentiation

    Zhou, S., Szczesna, K., Ochalek, A., Kobolák, J., Varga, E., Nemes, C., Chandrasekaran, A., Rasmussen, M., Cirera, Susanna, Hyttel, P., Dinnyés, A., Freude, Kristine & Avci, H. X., 2016, In: Stem Cells International. 2016, 15 p., 4937689.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B

    Zhang, Y., Schmid, B., Nielsen, T. T., Nielsen, Jørgen Erik, Clausen, C., Hyttel, P., Holst, B. & Freude, Kristine, 2016, In: Stem Cell Research. 17, 1, p. 151-153 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B

    Zhang, Y., Schmid, B., Qas Younan, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA. & 4 others, Holst, B., Clausen, C., Hyttel, P. & Freude, Kristine, 2017, In: Stem Cell Reports. 8, 3, p. 648-658

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B

    Zhang, Y., Schmid, B., Nielsen, T. T., Nielsen, Jørgen Erik, Clausen, C., Hyttel, P., Holst, B. & Freude, Kristine, Jul 2016, In: Stem Cell Research. 17, 1, p. 148-150 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Mitochondrial Spare Respiratory Capacity Is Negatively Correlated with Nuclear Reprogramming Efficiency

    Yan, Z., Al-Saaidi, R. A., Fernandez Guerra, P., Freude, Kristine, Olsen, R. K. J., Jensen, U. B., Gregersen, N., Hyttel, P., Bolund, L., Aagaard, L., Bross, P. & Luo, Y., 2017, In: Stem Cells and Development. 26, 3, p. 166-176

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts

    Xiong, K., Zhou, Y., Blichfeld, K. A., Hyttel, P., Bolund, L., Freude, Kristine & Luo, Y., Jun 2017, In: Cellular Reprogramming. 19, 3, p. 189-198 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM)

    Xiong, K., Zhou, Y., Hyttel, P., Bolund, L., Freude, Kristine & Luo, Y., Nov 2016, In: Stem Cell Research. 17, 3, p. 665-669 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid

    Walls, K. C., Coskun, P., Gallegos-Perez, J. L., Zadourian, N., Freude, Kristine, Rasool, S., Blurton-Jones, M., Green, K. N. & LaFerla, F. M., 2012, In: Journal of Biological Chemistry. 287, 36, p. 30317-30327 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Essential Roles of Lactate in Müller Cell Survival and Function

    Vohra, Rupali, Aldana, Blanca, Jensen, Dorte Skytt, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Dec 2018, In: Molecular Neurobiology. 55, 12, p. 9108-9121 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Muller cell survival and function is maintained by the presence of lactate

    Vohra, Rupali, Skytt, D. M., Aldana, Blanca, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, Jul 2018, p. 1480. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  13. Published

    Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington’s Disease?

    Duque Villegas, Luisana Carolina, Nørremølle, Anne, Freude, Kristine & Vilhardt, Frederik, 2021, In: Frontiers in Aging Neuroscience. 13, 20 p., 736734.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1

    Tubsuwan, A., Pires, C., Rasmussen, M. A., Schmid, B., Nielsen, Jørgen Erik, Hjermind, L. E., Hall, Vanessa Jane, Nielsen, T. T., Waldemar, Gunhild, Hyttel, P., Clausen, C., Kitiyanant, N., Freude, Kristine & Holst, B., Jan 2016, In: Stem Cell Research. 16, 1, p. 110-112 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease

    Tams, A. L. M., Sanz-Morello, B., Westi, Emil Winther, Mouhammad, Zaynab Ahmad, Andersen, Jens Velde, Freude, Kristine, Vohra, Rupali, Hannibal, Jens, Aldana, Blanca & Kolko, Miriam, 2022, In: Cellular and Molecular Neurobiology. 42, 1, p. 291–303

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    In vitro production of bovine embryos: revisiting oocyte development and application of systems biology

    Stroebech, L., Mazzoni, G., Pedersen, H. S., Freude, Kristine, Kadarmideen, H., Callesen, H. & Hyttel, P., 1 Aug 2015, In: Animal Reproduction. 12, 3, p. 465-472 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms

    Dittlau, Katarina Stoklund, Terrie, L., Baatsen, P., Kerstens, A., De Swert, L., Janky, R., Corthout, N., Masrori, P., Van Damme, P., Hyttel, P., Meyer, M., Thorrez, L., Freude, Kristine & Van Den Bosch, L., 2023, In: Molecular Neurodegeneration. 18, 1, 5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Role of S1P-receptor and Rho-kinase in myogenic tone in mesenteric and cerebral arteries of young vs. middle-aged mice

    Skovsted, Gry Freja, Aupetit, A., Björling , K., Haanes, K. A., Syberg, S., Jørgensen, N. R., Freude, Kristine, Pearson, J. T. & Jensen, Lars Jørn, 2023, In: Acta Physiologica. 239, S728, e14042.

    Research output: Contribution to journalConference abstract in journalCommunication

  19. A Sox9/Fgf feed-forward loop maintains pancreatic organ identity

    Seymour, Philip Allan, Shih, H. P., Patel, N. A., Freude, Kristine, Xie, R., Lim, C. J. & Sander, M., Sep 2012, In: Development. 139, 18, p. 3363-72 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. SOX9 is required for maintenance of the pancreatic progenitor cell pool

    Seymour, Philip Allan, Freude, Kristine, Tran, M. N., Mayes, E. E., Jensen, J., Kist, R., Scherer, G. & Sander, M., 6 Feb 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 6, p. 1865-70 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation

    Seymour, Philip Allan, Freude, Kristine, Dubois, C. L., Shih, H., Patel, N. A. & Sander, M., 1 Nov 2008, In: Advances in Developmental Biology. 323, 1, p. 19-30 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Initial embryology and pluripotent stem cells in the pig: the quest for establishing the pig as a model for cell therapy

    Secher, Jan Bojsen-Møller, Callesen, H., Freude, Kristine & Hyttel, P., 1 Jan 2016, In: Theriogenology. 85, 1, p. 162-171 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Optimization of three-dimensional imaging on in vitro produced porcine blastocysts and chimeras for stem cell testing: a technology report.

    Secher, Jan Bojsen-Møller, Freude, Kristine, Li, R. & Callesen, H., 2015, In: Stem Cells and Development. 24, 9, p. 1141-1145 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells

    Secher, J. O. B., Ceylan, A., Mazzoni, G., Mashayekhi-Nezamabadi, K., Li, T., Muenthaisong, S., Nielsen, T., Li, D., Li, S., Petkov, S. G., Cirera Salicio, S., Luo, Y., Thombs, L., Kadarmideen, H., Dinnyés, A., Bolund, L., Roelen, B. A., Schmidt, M., Callesen, H., Hyttel, P. & 1 others, Freude, Kristine, 2017, In: Molecular Reproduction and Development. 84, 3, p. 229-245

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals

    Secher, Jan Bojsen-Møller, Liu, Y., Petkov, S. G., Li, D., Hall, Vanessa Jane, Schmidt, M., Callesen, H., Freude, Kristine & Hyttel, P., 2017, In: Animal Reproduction Science. 178, p. 40-49

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 38189431