Kristine Freude
Professor
Pathobiological Sciences
Grønnegårdsvej 7, 1870 Frederiksberg C
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Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells
Kobolák, J., Molnár, K., Varga, E., Bock, I., Jezsó, B., Téglási, A., Zhou, S., Lo Giudice, M., Hoogeveen-Westerveld, M., Pijnappel, W. P., Phanthong, P., Varga, N., Kitiyanant, N., Freude, Kristine, Nakanishi, H., László, L., Hyttel, P. & Dinnyés, A., 2019, In: Experimental Cell Research. 380, 2, p. 216-233 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts
Li, D., Secher, Jan Bojsen-Møller, Juhl, M., Mashayekhi-Nezamabadi, K., Nielsen, T. T., Holst, B., Hyttel, P., Freude, Kristine & Hall, Vanessa Jane, 2017, In: Cell Cycle. 16, 11, p. 1070-1084Research output: Contribution to journal › Journal article › Research › peer-review
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Generation of transgene-free porcine intermediate type induced pluripotent stem cells
Li, D., Secher, Jan Bojsen-Møller, Hyttel, P., Ivask, M., Kolko, Miriam, Hall, Vanessa Jane & Freude, Kristine, 2018, In: Cell Cycle. 17, 23, p. 2547-2563 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a M146I mutation in PSEN1
Li, T., Pires, C., Nielsen, T. T., Waldemar, Gunhild, Hjermind, L. E., Nielsen, Jørgen Erik, Dinnyes, A., Holst, B., Hyttel, P. & Freude, Kristine, Mar 2016, In: Stem Cell Research. 16, 2, p. 334-337 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying an A79V mutation in PSEN1
Li, T., Pires, C., Nielsen, T. T., Waldemar, Gunhild, Hjermind, L. E., Nielsen, Jørgen Erik, Dinnyes, A., Hyttel, P. & Freude, Kristine, Mar 2016, In: Stem Cell Research. 16, 2, p. 229-332 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation of neural progenitor cells (NPC) from porcine induced pluripotent stem cells (piPSC)
Machado, L. S., Pieri, N. C. G., Botigelli, R. C., de Castro, R. V. G., de Souza, A. F., Bridi, A., Lima, M. A., Fantinato Neto, P., de Figueiredo Pessôa, L. V., Martins, S. M. M. K., de Andrade, A. F. C., Freude, Kristine & Bressan, F. F., 2020, In: Journal of Tissue Engineering and Regenerative Medicine. 14, 12, p. 1880-1891Research output: Contribution to journal › Journal article › Research › peer-review
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The Nav1.5 variant G213D found in patients with MEPPC is associated with increased window current and gating pore current
Magnusson, H. B. D., Geryk, M., Cordeiro, J. M., Lind, J. U., Jensen, H. K., Freude, Kristine & Callø, Kirstine, 16 Sep 2023.Research output: Contribution to conference › Poster › Communication
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Systems Biology and Stem Cell Pluripotency: Revisiting the Discovery of Induced Pluripotent Stem Cell
Mashayekhi, K., Hall, Vanessa Jane, Freude, Kristine, Høffding, M. K., Labusca, L. & Hyttel, P., 29 Oct 2016, Systems Biology in Animal Production and Health. Kadarmideen, H. N. (ed.). 1 ed. Springer, Vol. 2. p. 127-154 28 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Co-expression network analysis to identify pluripotency biomarkers in bovine and porcine embryos
Mazzoni, G., Freude, Kristine, Hall, Vanessa Jane, Mashayekhi-Nezamabadi, K., Hyttel, P., Dinnyés, A. & Kadarmideen, H., 2015. 1 p.Research output: Contribution to conference › Poster › Research › peer-review
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Identification of potential biomarkers in donor cows for in vitro embryo production by granulosa cell transcriptomics
Mazzoni, G., Salleh, S. M., Freude, Kristine, Pedersen, H. S., Stroebech, L., Callesen, H., Hyttel, P. & Kadarmideen, H. N., 2017, In: PLOS ONE. 12, 4, 27 p., e0175464.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence
Mazzoni, G., Razza, E., Pedersen, H. S., Secher, Jan Bojsen-Møller, Kadarmideen, H. N., Callesen, H., Stroebech, L., Freude, Kristine & Hyttel, P., 2017, In: Animal Reproduction. 14, 3, p. 482-489 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic protection modifications: Moving beyond the binary distinction between therapy and enhancement for human genome editing
Mikkelsen, R. C. B., Frederiksen, Henriette Reventlow S, Gjerris, Mickey, Holst, B., Hyttel, P., Luo, Y., Freude, Kristine & Sandøe, Peter, 2019, In: CRISPR Journal. 2, 6, p. 362-369 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Implications of SNP-triggered miRNA dysregulation in Schizophrenia development
Mohamed, Fadumo Abdullahi & Freude, Kristine, 26 Jan 2024, In: Frontiers in Genetics.Research output: Contribution to journal › Journal article › Research › peer-review
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Human induced pluripotent cells in personalized treatment of monogenic epilepsies
Mohammad, N. A., Freude, Kristine, Haukedal, H., Tümer, Asuman Zeynep & Møller, R. S., 2020, In: Journal of Translational Genetics and Genomics. 2020, 4, p. 238-250Research output: Contribution to journal › Review › Research › peer-review
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Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation
Ochalek, A., Mihalik, B., Avci, H. X., Chandrasekaran, Abinaya, Téglási, A., Bock, I., Giudice, M. L., Táncos, Z., Molnár, K., László, L., Nielsen, Jørgen Erik, Holst, B., Freude, Kristine, Hyttel, P., Kobolák, J. & Dinnyés, A., Dec 2017, In: Alzheimer's Research and Therapy. 9, 1, 19 p., 90.Research output: Contribution to journal › Journal article › Research › peer-review
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USP30 inhibition induces mitophagy and reduces oxidative stress in parkin-deficient human neurons
Okarmus, J., Agergaard, J. B., Stummann, T., Haukedal, H., Ambjørn, M., Freude, Kristine, Fog, K. & Meyer, M., 14 Jan 2024, In: Nature.Research output: Contribution to journal › Journal article › Research › peer-review
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WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA.
Pan, X., Xiong, K., Anthon, Christian, Hyttel, P., Freude, Kristine, Jensen, Lars Juhl & Gorodkin, Jan, 6 Nov 2018, In: Genes. 9, 11, 11 p., 536.Research output: Contribution to journal › Journal article › Research › peer-review
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Canine induced pluripotent stem cells: an in vitro approach to validate the dog as a large animal model for Alzheimer's disease
Pessoa, L. V. D. F., Chandrasekaran, Abinaya, Thomsen, B. B., Berendt, Mette, Hyttel, P. & Freude, Kristine, Sep 2020, iPSCs from Diverse Species. 1 ed. Elsevier: Academic Press, Vol. 2.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Induced pluripotent stem cells throughout the animal kingdom: Availability and applications
Pessôa, L. V. D. F., Bressan, F. F. & Freude, Kristine, 2019, In: World Journal of Stem Cells. 11, 8, p. 491-505 15 p.Research output: Contribution to journal › Review › Research › peer-review
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Toward Development of Pluripotent Porcine Stem Cells by Road Mapping Early Embryonic Development
Petkov, S., Freude, Kristine, Mashayekhi-Nezamabadi, K., Hyttel, P. & Hall, Vanessa Jane, Mar 2017, Animal Models and Human Reproduction: Cell and Molecular Approaches with Reference to Human Reproduction. Schatten, H. & Constantinescu, G. M. (eds.). Wiley-Blackwell, p. 485-508 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Human Induced Pluripotent stem cells and their derivatives for disease modeling and therapeutic applications in Alzheimer's disease
Pires, C., Hall, Vanessa Jane & Freude, Kristine, 20 May 2016, Alzheimer's disease. SMGroup, p. 1-25 25 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1
Pires, C., Schmid, B., Petræus, C., Poon, A. F., Nimsanor, N., Nielsen, T. T., Waldemar, Gunhild, Hjermind, L. E., Nielsen, Jørgen Erik, Hyttel, P. & Freude, Kristine, Sep 2016, In: Stem Cell Research. 17, 2, p. 285-288 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges
Poon, A., Zhang, Y., Chandrasekaran, Abinaya, Phanthong, P., Schmid, B., Nielsen, T. T. & Freude, Kristine, 2017, In: New Biotechnology. 39, Part B, p. 190-198Research output: Contribution to journal › Review › Research › peer-review
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Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1
Poon, A. F., Li, T., Pires, C., Nielsen, T. T., Nielsen, Jørgen Erik, Holst, B., Dinnyes, A., Hyttel, P. & Freude, Kristine, Nov 2016, In: Stem Cell Research. 17, 3, p. 470-473 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation of a gene-corrected isogenic control hiPSC line derived from a familial Alzheimer's disease patient carrying a L150P mutation in presenilin 1
Poon, A. F., Schmid, B., Pires, C., Nielsen, T. T., Hjermind, L. E., Nielsen, Jørgen Erik, Holst, B., Hyttel, P. & Freude, Kristine, Nov 2016, In: Stem Cell Research. 17, 3, p. 466-469 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38189431
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Induced pluripotent stem cells derived from Alzheimer's disease patients: the promise, the hope and the path ahead
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Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
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330
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Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM)
Research output: Contribution to journal › Journal article › Research › peer-review
Published