Kristine Freude

Kristine Freude

Professor


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  1. Published

    Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene.

    Frederiksen, Henriette Reventlow S, Holst, B., Mau-Holzmann, U. A., Freude, Kristine & Schmid, B., Mar 2019, In: Stem Cell Research. 35, 4 p., 101403.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Novel traceable CRISPR-Cas9 engineered human embryonic stem cell line (E1C3 + hSEAP + 2xKO + pCD47), has potential to evade immune detection in pigs

    Frederiksen, Henriette Reventlow S, Skov, Søren, Tveden-Nyborg, Pernille, Freude, Kristine & Doehn, U., 7 May 2024, In: Stem Cell Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Induced pluripotent stem cells derived from Alzheimer's disease patients: the promise, the hope and the path ahead

    Freude, Kristine, Pires, C., Hyttel, P. & Hall, Vanessa Jane, 2014, In: Journal of Clinical Medicine. 3, 4, p. 1402-1436 35 p.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Deciphering the naïve state of porcine iPSC

    Freude, Kristine, Secher, Jan Bojsen-Møller, Mashayekhi-Nezamabadi, K., Petkov, S. G., Nielsen, T. T., Ceylan, A., Poligari, S., Dinnyes, A. & Hyttel, P., 18 Jun 2014. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  5. Soluble amyloid precursor protein induces rapid neural differentiation of human embryonic stem cells

    Freude, Kristine, Penjwini, M., Davis, J. L., LaFerla, F. M. & Blurton-Jones, M., 2011, In: The Journal of Biological Chemistry. 286, 27, p. 24264-24274 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Dementia, Brain Disorders and Molecular Mechanisms

    Freude, Kristine & Krauss, S., 2019, In: Journal of Molecular Biology. 431, 9, p. 1709-1710

    Research output: Contribution to journal › Editorial › Research

  7. Published

    APOE4 IS INSTRUMENTAL IN AUGMENTING RHOA KINASE PHOSPHORYLATION AND CONTRIBUTES THEREBY TO CLASSICAL ALZHEIMER’S DISEASE NEURON PHENOTYPES

    Freude, Kristine, Dittlau, Katarina Stoklund & Tao, Ruixin, 5 Mar 2024.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  8. Published

    Mutations in the FTSJ1 gene coding for a novel S-adenosylmethionine-binding protein cause nonsyndromic X-linked mental retardation

    Freude, K., Hoffmann, K., Jensen, L., Delatycki, M. B., des Portes, V., Moser, B., Hamel, B., van Bokhoven, H., Moraine, C., Fryns, J., Chelly, J., Gécz, J., Lenzner, S., Kalscheuer, V. M., Ropers, H. & Freude, Kristine, Aug 2004, In: American Journal of Human Genetics. 75, 2, p. 305-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Editorial: Metabolic Alterations in Neurodegenerative Disorders

    Freude, Kristine, Moreno-gonzalez, I., Rodriguez-ortiz, C. J. & Baglietto-vargas, D., 2022, In: Frontiers in Aging Neuroscience. 14, 3 p., 833109.

    Research output: Contribution to journal › Editorial › Research › peer-review

  10. Published

    Enrichment of retinal ganglion and Müller glia progenitors from retinal organoids derived from human induced pluripotent stem cells - possibilities and current limitations

    Freude, Kristine, Saruhanian, S., Mccauley, A., Paterson, C., Odette, M., Oostenink, A., Hyttel, P., Gillies, M., Haukedal, H. & Kolko, Miriam, 2020, In: World Journal of Stem Cells. 12, 10, p. 1171-1183

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Metabolic impairments in neurons and astrocytes derived from human induced pluripotent stem cells of Alzheimer's disease patients

    Garcia, B. A., Salcedo, C., Hyttel, P., Waagepetersen, Helle S. & Freude, Kristine, 2019, p. 111-111.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  12. Published

    Potential Retinal Biomarkers in Alzheimer's Disease

    Garcia Bermudez, Mariana Yolotzin, Vohra, Rupali, Freude, Kristine, van Wijngaarden, P., Martin, K. K., Thomsen, M. S., Aldana, Blanca & Kolko, Miriam, 2023, In: International Journal of Molecular Sciences (Online). 24, 21, 26 p., 15834.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets

    Garcia Bermudez, Mariana Yolotzin, Freude, Kristine, Mouhammad, Zaynab Ahmad, van Wijngaarden, P., Martin, K. K. & Kolko, Miriam, 2021, In: Frontiers in Neurology. 12, 17 p., 624983.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    iPSC-derived Microglia for Disease Modeling of Frontotemporal Dementia 3

    Haukedal, H., Freude, Kristine, Garcia, B. A., Corsi, G., Gadekar, V. & Gorodkin, Jan, 2021, In: Glia. 69, S1, p. E480-E481 T14-066D.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  15. Published

    Implications of Microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

    Haukedal, H. & Freude, Kristine, 2019, In: Journal of Molecular Biology. 431, 9, p. 1818-1829

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Golgi fragmentation: One of the earliest organelle phenotypes in Alzheimer's disease neurons

    Haukedal, H., Corsi, G. I., Gadekar, V. P., Doncheva, N. T., Kedia, S., de Haan, N., Chandrasekaran, A., Jensen, P., Schiønning, P., Vallin, S., Marlet, F. R., Poon, A., Pires, C., Agha, F. K., Wandall, H. H., Cirera, S., Simonsen, A. H., Nielsen, T. T., Nielsen, J. E., Hyttel, P. & 7 others, Muddashetty, R., Aldana, Blanca, Gorodkin, Jan, Nair, D., Meyer, M., Larsen, M. R. & Freude, Kristine, 2023, In: Frontiers in Neuroscience. 17, 17 p., 1120086.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Patient iPSC-Derived Neorons for Disease Modeling of Familiar Alzheimer's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, Oct 2020.

    Research output: Contribution to conference › Conference abstract for conference › Research

  18. Published

    Inflammatory Responses and Sex Differences of Patient Derived Cell Models of Microglia in Alzheimer's Disease

    Haukedal, H., Thomassen, F., Kadlecová, Marion & Freude, Kristine, 20 May 2024.

    Research output: Contribution to conference › Poster › Communication

  19. Published

    Patient iPSC-Derived Neurons for Disease Modeling of Familiar Alzheier's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, 26 Mar 2019.

    Research output: Contribution to conference › Poster › Communication

  20. Published

    Implications of Glycosylation in Alzheimer’s Disease

    Haukedal, H. & Freude, Kristine, 2021, In: Frontiers in Neuroscience. 14, 18 p., 625348.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3

    Haukedal, H., Syshøj Lorenzen, S., Westi, Emil Winther, Corsi, G., Gadekar, V. P., McQuade, A., Davtyan, H., Doncheva, Nadezhda Tsankova, Schmid, B., Chandrasekaran, Abinaya, Seemann, Ernst Stefan, Cirera, Susanna, Blurton-Jones, M., Meyer, M., Gorodkin, Jan, Aldana, Blanca & Freude, Kristine, 2023, In: Brain, Behavior, and Immunity. 113, p. 353-373

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop: Effect on cultured human conjunctival goblet cells and their physicochemical properties

    Nagstrup, Anne Hedengran, Freiberg, Josefine, Hansen, Pernille May, Jacobsen, Jette, Larsen, Susan Weng, Rønholt, Stine, Freude, Kristine, Boix‐lemonche, G., Petrovski, G., Heegaard, Steffen & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, 7, p. 819-827

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Oocytes, embryos and pluripotent stem cells from a biomedical perspective

    Hyttel, P., Pessôa, L. V. D. F., Secher, Jan Bojsen-Møller, Dittlau, Katarina Stoklund, Freude, Kristine, Hall, Vanessa Jane, Fair, T., Assey, R. J., Laurincik, J., Callesen, H., Greve, T. & Stroebech, L. B., 2019, In: Animal Reproduction. 16, 3, p. 508-523 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. X-linked mental retardation: a comprehensive molecular screen of 47 candidate genes from a 7.4 Mb interval in Xp11

    Jensen, L. R., Lenzner, S., Moser, B., Freude, Kristine, Tzschach, A., Wei, C., Fryns, J., Chelly, J., Turner, G., Moraine, C., Hamel, B., Ropers, H. & Kuss, A. W., 2007, In: European Journal of Human Genetics. 15, 1, p. 68-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Complexity of Sex Differences and Their Impact on Alzheimer’s Disease

    Kadlecová, Marion, Freude, Kristine & Haukedal, H., 24 Apr 2023, In: Biomedicines. 11, 5, 29 p., 1261.

    Research output: Contribution to journal › Review › Research › peer-review

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