Kristine Freude

Kristine Freude

Professor


  1. 2020
  2. Published

    Human induced pluripotent cells in personalized treatment of monogenic epilepsies

    Mohammad, N. A., Freude, Kristine, Haukedal, H., Tümer, Asuman Zeynep & Møller, R. S., 2020, In: Journal of Translational Genetics and Genomics. 2020, 4, p. 238-250

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Mutation in FTD3 CHMP2B causes impaired autography and distorted energy metabolism cumulating in reactive astrocyte phenotypes

    Chandrasekaran, A., Dittlau, K. S., Corsi, G., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  4. Published

    Mutations in FTD3 CHMP2B causes impaired autophagy and distorted energy metabolism cumulating in reactive astrocyte phenotypes

    Chandrasekaran, A., Dittlau, K. S., Corsi, G., Doncheva, N. T., Haukedal, H., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

    Research output: Contribution to conferencePosterResearch

  5. 2019
  6. Published

    Patient iPSC-Derived Neurons for Disease Modeling of Familiar Alzheier's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, 26 Mar 2019.

    Research output: Contribution to conferencePosterCommunication

  7. Published

    Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene.

    Frederiksen, Henriette Reventlow S, Holst, B., Mau-Holzmann, U. A., Freude, Kristine & Schmid, B., Mar 2019, In: Stem Cell Research. 35, 4 p., 101403.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene

    Frederiksen, Henriette Reventlow S, Holst, B., Ramakrishna, S., Muddashetty, R., Schmid, B. & Freude, Kristine, 1 Jan 2019, In: Stem Cell Research. 34, 5 p., 101368.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Cell type specific expression of toll-like receptors in human brains and implications in Alzheimer's disease

    Frederiksen, Henriette Reventlow S, Haukedal, H. & Freude, Kristine, 2019, In: BioMed Research International. 2019, 18 p., 7420189.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Dementia, Brain Disorders and Molecular Mechanisms

    Freude, Kristine & Krauss, S., 2019, In: Journal of Molecular Biology. 431, 9, p. 1709-1710

    Research output: Contribution to journalEditorialResearch

  11. Published

    Genetic protection modifications: Moving beyond the binary distinction between therapy and enhancement for human genome editing

    Mikkelsen, R. C. B., Frederiksen, Henriette Reventlow S, Gjerris, Mickey, Holst, B., Hyttel, P., Luo, Y., Freude, Kristine & Sandøe, Peter, 2019, In: CRISPR Journal. 2, 6, p. 362-369 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Implications of Microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

    Haukedal, H. & Freude, Kristine, 2019, In: Journal of Molecular Biology. 431, 9, p. 1818-1829

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Induced pluripotent stem cells throughout the animal kingdom: Availability and applications

    Pessôa, L. V. D. F., Bressan, F. F. & Freude, Kristine, 2019, In: World Journal of Stem Cells. 11, 8, p. 491-505 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Metabolic impairments in neurons and astrocytes derived from human induced pluripotent stem cells of Alzheimer's disease patients

    Garcia, B. A., Salcedo, C., Hyttel, P., Waagepetersen, Helle S. & Freude, Kristine, 2019, p. 111-111.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  15. Published

    Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells

    Kobolák, J., Molnár, K., Varga, E., Bock, I., Jezsó, B., Téglási, A., Zhou, S., Lo Giudice, M., Hoogeveen-Westerveld, M., Pijnappel, W. P., Phanthong, P., Varga, N., Kitiyanant, N., Freude, Kristine, Nakanishi, H., László, L., Hyttel, P. & Dinnyés, A., 2019, In: Experimental Cell Research. 380, 2, p. 216-233 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Oocytes, embryos and pluripotent stem cells from a biomedical perspective

    Hyttel, P., Pessôa, L. V. D. F., Secher, Jan Bojsen-Møller, Dittlau, Katarina Stoklund, Freude, Kristine, Hall, Vanessa Jane, Fair, T., Assey, R. J., Laurincik, J., Callesen, H., Greve, T. & Stroebech, L. B., 2019, In: Animal Reproduction. 16, 3, p. 508-523 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2018
  18. Published

    Essential Roles of Lactate in Müller Cell Survival and Function

    Vohra, Rupali, Aldana, Blanca, Jensen, Dorte Skytt, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Dec 2018, In: Molecular Neurobiology. 55, 12, p. 9108-9121 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA.

    Pan, X., Xiong, K., Anthon, Christian, Hyttel, P., Freude, Kristine, Jensen, Lars Juhl & Gorodkin, Jan, 6 Nov 2018, In: Genes. 9, 11, 11 p., 536.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Muller cell survival and function is maintained by the presence of lactate

    Vohra, Rupali, Skytt, D. M., Aldana, Blanca, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, Jul 2018, p. 1480. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  21. Published

    Generation of transgene-free porcine intermediate type induced pluripotent stem cells

    Li, D., Secher, Jan Bojsen-Møller, Hyttel, P., Ivask, M., Kolko, Miriam, Hall, Vanessa Jane & Freude, Kristine, 2018, In: Cell Cycle. 17, 23, p. 2547-2563 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Mammalian embryo comparison identifies novel pluripotency genes associated with the naive or primed state

    Bernardo, A. S., Jouneau, A., Marks, H., Kensche, P., Kobolak, J., Freude, K., Hall, V., Feher, A., Polgar, Z., Sartori, C., Bock, I., Louet, C., Faial, T., Kerstens, H. H. D., Bouissou, C., Parsonage, G., Mashayekhi, K., Smith, J. C., Lazzari, G., Hyttel, P. & 4 others, Stunnenberg, H. G., Huynen, M., Pedersen, R. A. & Dinnyes, A., 2018, In: Biology Open. 7, 8, 17 p., bio033282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2017
  24. Published

    Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation

    Ochalek, A., Mihalik, B., Avci, H. X., Chandrasekaran, Abinaya, Téglási, A., Bock, I., Giudice, M. L., Táncos, Z., Molnár, K., László, L., Nielsen, Jørgen Erik, Holst, B., Freude, Kristine, Hyttel, P., Kobolák, J. & Dinnyés, A., Dec 2017, In: Alzheimer's Research and Therapy. 9, 1, 19 p., 90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts

    Xiong, K., Zhou, Y., Blichfeld, K. A., Hyttel, P., Bolund, L., Freude, Kristine & Luo, Y., Jun 2017, In: Cellular Reprogramming. 19, 3, p. 189-198 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Toward Development of Pluripotent Porcine Stem Cells by Road Mapping Early Embryonic Development

    Petkov, S., Freude, Kristine, Mashayekhi-Nezamabadi, K., Hyttel, P. & Hall, Vanessa Jane, Mar 2017, Animal Models and Human Reproduction: Cell and Molecular Approaches with Reference to Human Reproduction. Schatten, H. & Constantinescu, G. M. (eds.). Wiley-Blackwell, p. 485-508 24 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  27. Published

    Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons

    Aldana, Blanca, Zhang, Y., Lihme, M. F., Bak, Lasse Kristoffer, Nielsen, Jørgen Erik, Holst, B., Hyttel, P., Freude, Kristine & Waagepetersen, Helle S., 2017, In: Neurochemistry International. 106, p. 48-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals

    Secher, Jan Bojsen-Møller, Liu, Y., Petkov, S. G., Li, D., Hall, Vanessa Jane, Schmidt, M., Callesen, H., Freude, Kristine & Hyttel, P., 2017, In: Animal Reproduction Science. 178, p. 40-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts

    Li, D., Secher, Jan Bojsen-Møller, Juhl, M., Mashayekhi-Nezamabadi, K., Nielsen, T. T., Holst, B., Hyttel, P., Freude, Kristine & Hall, Vanessa Jane, 2017, In: Cell Cycle. 16, 11, p. 1070-1084

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38189431