Differential serodiagnostics of Toxocara canis and Toxocara cati - is it possible?

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Differential serodiagnostics of Toxocara canis and Toxocara cati - is it possible? / Poulsen, C. S.; Skov, Søren; Yoshida, A.; Skallerup, Per; Maruyama, H.; Thamsborg, Stig Milan; Nejsum, Peter.

In: Parasite Immunology, Vol. 37, No. 4, 04.2015, p. 204-207.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Poulsen, CS, Skov, S, Yoshida, A, Skallerup, P, Maruyama, H, Thamsborg, SM & Nejsum, P 2015, 'Differential serodiagnostics of Toxocara canis and Toxocara cati - is it possible?', Parasite Immunology, vol. 37, no. 4, pp. 204-207. https://doi.org/10.1111/pim.12181

APA

Poulsen, C. S., Skov, S., Yoshida, A., Skallerup, P., Maruyama, H., Thamsborg, S. M., & Nejsum, P. (2015). Differential serodiagnostics of Toxocara canis and Toxocara cati - is it possible? Parasite Immunology, 37(4), 204-207. https://doi.org/10.1111/pim.12181

Vancouver

Poulsen CS, Skov S, Yoshida A, Skallerup P, Maruyama H, Thamsborg SM et al. Differential serodiagnostics of Toxocara canis and Toxocara cati - is it possible? Parasite Immunology. 2015 Apr;37(4):204-207. https://doi.org/10.1111/pim.12181

Author

Poulsen, C. S. ; Skov, Søren ; Yoshida, A. ; Skallerup, Per ; Maruyama, H. ; Thamsborg, Stig Milan ; Nejsum, Peter. / Differential serodiagnostics of Toxocara canis and Toxocara cati - is it possible?. In: Parasite Immunology. 2015 ; Vol. 37, No. 4. pp. 204-207.

Bibtex

@article{7b37fe3371b4461eb519d870f6f9aa3e,
title = "Differential serodiagnostics of Toxocara canis and Toxocara cati - is it possible?",
abstract = "One of the most common zoonotic helminth infections is caused by species in the genus Toxocara, particularly Toxocara canis and T. cati (Syn. T. mystax). However, their relative contribution to toxocarosis in humans remains largely unknown because causative larvae are seldom recovered and uncertainties regarding the validity of existing serological assays. In this study, we used sera from a pig model experimentally infected with T. canis and T. cati to evaluate whether a Western blot could discriminate between the two species. No proteins were observed that could be used as a diagnostic tool. In addition, a heterogenic protein pattern between individual hosts was found, which was most pronounced in the T. cati-infected pigs. There is therefore an urgent need to optimize and validate current methods or develop new species-specific serological methods in order to implement appropriate control measures.",
author = "Poulsen, {C. S.} and S{\o}ren Skov and A. Yoshida and Per Skallerup and H. Maruyama and Thamsborg, {Stig Milan} and Peter Nejsum",
note = "{\textcopyright} 2015 John Wiley & Sons Ltd.",
year = "2015",
month = apr,
doi = "10.1111/pim.12181",
language = "English",
volume = "37",
pages = "204--207",
journal = "Parasite Immunology",
issn = "0141-9838",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Differential serodiagnostics of Toxocara canis and Toxocara cati - is it possible?

AU - Poulsen, C. S.

AU - Skov, Søren

AU - Yoshida, A.

AU - Skallerup, Per

AU - Maruyama, H.

AU - Thamsborg, Stig Milan

AU - Nejsum, Peter

N1 - © 2015 John Wiley & Sons Ltd.

PY - 2015/4

Y1 - 2015/4

N2 - One of the most common zoonotic helminth infections is caused by species in the genus Toxocara, particularly Toxocara canis and T. cati (Syn. T. mystax). However, their relative contribution to toxocarosis in humans remains largely unknown because causative larvae are seldom recovered and uncertainties regarding the validity of existing serological assays. In this study, we used sera from a pig model experimentally infected with T. canis and T. cati to evaluate whether a Western blot could discriminate between the two species. No proteins were observed that could be used as a diagnostic tool. In addition, a heterogenic protein pattern between individual hosts was found, which was most pronounced in the T. cati-infected pigs. There is therefore an urgent need to optimize and validate current methods or develop new species-specific serological methods in order to implement appropriate control measures.

AB - One of the most common zoonotic helminth infections is caused by species in the genus Toxocara, particularly Toxocara canis and T. cati (Syn. T. mystax). However, their relative contribution to toxocarosis in humans remains largely unknown because causative larvae are seldom recovered and uncertainties regarding the validity of existing serological assays. In this study, we used sera from a pig model experimentally infected with T. canis and T. cati to evaluate whether a Western blot could discriminate between the two species. No proteins were observed that could be used as a diagnostic tool. In addition, a heterogenic protein pattern between individual hosts was found, which was most pronounced in the T. cati-infected pigs. There is therefore an urgent need to optimize and validate current methods or develop new species-specific serological methods in order to implement appropriate control measures.

U2 - 10.1111/pim.12181

DO - 10.1111/pim.12181

M3 - Journal article

C2 - 25711956

VL - 37

SP - 204

EP - 207

JO - Parasite Immunology

JF - Parasite Immunology

SN - 0141-9838

IS - 4

ER -

ID: 138152739