Environmental factors affecting challenge success in vaccination studies
Research output: Contribution to conference › Conference abstract for conference › Research
Standard
Environmental factors affecting challenge success in vaccination studies. / Chettri, Jiwan Kumar; Skov, Jakob; Dalsgaard, Inger; Buchmann, Kurt.
2013. Abstract from DAFINET Workshop, Copenhagen, Denmark.Research output: Contribution to conference › Conference abstract for conference › Research
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - ABST
T1 - Environmental factors affecting challenge success in vaccination studies
AU - Chettri, Jiwan Kumar
AU - Skov, Jakob
AU - Dalsgaard, Inger
AU - Buchmann, Kurt
PY - 2013/11/12
Y1 - 2013/11/12
N2 - We have tested the efficacies of two different vaccines (a commercial versus an experimental vaccine – both being oil adjuvanted) for rainbow trout against furunculosis caused by Aeromonas salmonicida infections. However, when challenging fish with live bacteria in order to assess protection following vaccination, the administration of the pathogen is important for the outcome ofthe experiments. We have therefore also compared injection challenge with cohabitation challenge. In addition, when doing so we also investigated the influence of environmental conditions such as salinity and temperature on the protection recorded. Thus, challenge studies were conducted at two temperatures (12 and 19°C) and at two salinities (0 and 15 ppt). Mortalities following challenge were recorded and RPS calculated for each group. Side effects of the vaccines were evaluated by using the Speilberg scale. Results from the challenge studies will be presented.
AB - We have tested the efficacies of two different vaccines (a commercial versus an experimental vaccine – both being oil adjuvanted) for rainbow trout against furunculosis caused by Aeromonas salmonicida infections. However, when challenging fish with live bacteria in order to assess protection following vaccination, the administration of the pathogen is important for the outcome ofthe experiments. We have therefore also compared injection challenge with cohabitation challenge. In addition, when doing so we also investigated the influence of environmental conditions such as salinity and temperature on the protection recorded. Thus, challenge studies were conducted at two temperatures (12 and 19°C) and at two salinities (0 and 15 ppt). Mortalities following challenge were recorded and RPS calculated for each group. Side effects of the vaccines were evaluated by using the Speilberg scale. Results from the challenge studies will be presented.
M3 - Conference abstract for conference
T2 - DAFINET Workshop
Y2 - 12 November 2013 through 14 November 2013
ER -
ID: 100735068