Health promoting compounds in vegetables and fruits: A systematic approach for identifying plant components with impact on human health
Research output: Contribution to journal › Journal article › Research › peer-review
Vegetables contain unknown compounds with important health promoting effect. The described project defined and tested a two-step screening procedure for identification of such compounds. Step 1 is initial screening according to three criteria: 1.1, chemically reactive functional groups; 1.2, toxicity at high concentrations or other bioactivity; and 1.3, presence in healthy foods. Step 2 is testing for minimum criteria defining health-promoting compounds: 2.1, positive or biphasic ("hormesis") responses in bioassay; 2.2, human tissue concentrations corresponding to beneficial effects in bioassay; and 2.3, possibility to control content in food. Falcarinol from carrots fulfilled all 6 criteria and subsequently showed anticancer effect in rats.
Original language | English |
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Journal | Trends in Food Science and Technology |
Volume | 15 |
Issue number | 7-8 |
Pages (from-to) | 384-393 |
Number of pages | 10 |
ISSN | 0924-2244 |
DOIs | |
Publication status | Published - Jul 2004 |
ID: 316998846