Micro and nano-platforms for biological cell analysis

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Micro and nano-platforms for biological cell analysis. / Svendsen, W.E.; Castillo-León, J.; Lange, J.M.; Sasso, L.; Olsen, M.H.; Abaddi, M.; Andresen, Lars; Levinsen, Simon; Shah, P.; Vedarethinam, I.; Dimaki, Maria.

In: Sensors and Actuators A: Physical, Vol. 172, No. 1, 01.12.2011, p. 54-60.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Svendsen, WE, Castillo-León, J, Lange, JM, Sasso, L, Olsen, MH, Abaddi, M, Andresen, L, Levinsen, S, Shah, P, Vedarethinam, I & Dimaki, M 2011, 'Micro and nano-platforms for biological cell analysis', Sensors and Actuators A: Physical, vol. 172, no. 1, pp. 54-60. https://doi.org/10.1016/j.sna.2011.02.027

APA

Svendsen, W. E., Castillo-León, J., Lange, J. M., Sasso, L., Olsen, M. H., Abaddi, M., Andresen, L., Levinsen, S., Shah, P., Vedarethinam, I., & Dimaki, M. (2011). Micro and nano-platforms for biological cell analysis. Sensors and Actuators A: Physical, 172(1), 54-60. https://doi.org/10.1016/j.sna.2011.02.027

Vancouver

Svendsen WE, Castillo-León J, Lange JM, Sasso L, Olsen MH, Abaddi M et al. Micro and nano-platforms for biological cell analysis. Sensors and Actuators A: Physical. 2011 Dec 1;172(1):54-60. https://doi.org/10.1016/j.sna.2011.02.027

Author

Svendsen, W.E. ; Castillo-León, J. ; Lange, J.M. ; Sasso, L. ; Olsen, M.H. ; Abaddi, M. ; Andresen, Lars ; Levinsen, Simon ; Shah, P. ; Vedarethinam, I. ; Dimaki, Maria. / Micro and nano-platforms for biological cell analysis. In: Sensors and Actuators A: Physical. 2011 ; Vol. 172, No. 1. pp. 54-60.

Bibtex

@article{d6dc626a490244a9bd3f752a57e12fbc,
title = "Micro and nano-platforms for biological cell analysis",
abstract = "In this paper some technological platforms developed for biological cell analysis will be presented and compared to existing systems. In brief, we present a novel micro cell culture chamber based on diffusion feeding of cells, into which cells can be introduced and extracted after culturing using normal pipettes, thus making it readily usable for clinical laboratories. To enhance the functionality of such a chamber we have been investigating the use of active or passive 3D surface modifications. Active modifications involve miniature electrodes able to record electrical or electrochemical signals from the cells, while passive modifications involve the presence of a peptide nanotube based scaffold for the cell culturing that mimics the in vivo environment. Two applications involving fluorescent in situ hybridization (FISH) analysis and cancer cell sorting are presented, as examples of further analysis that can be done after cell culturing. A platform able to automate the entire process from cell culturing to cell analysis by means of simple plug and play of various self-contained, individually fabricated modules is finally described.",
author = "W.E. Svendsen and J. Castillo-Le{\'o}n and J.M. Lange and L. Sasso and M.H. Olsen and M. Abaddi and Lars Andresen and Simon Levinsen and P. Shah and I. Vedarethinam and Maria Dimaki",
year = "2011",
month = dec,
day = "1",
doi = "10.1016/j.sna.2011.02.027",
language = "English",
volume = "172",
pages = "54--60",
journal = "Sensors and Actuators A: Physical",
issn = "0924-4247",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Micro and nano-platforms for biological cell analysis

AU - Svendsen, W.E.

AU - Castillo-León, J.

AU - Lange, J.M.

AU - Sasso, L.

AU - Olsen, M.H.

AU - Abaddi, M.

AU - Andresen, Lars

AU - Levinsen, Simon

AU - Shah, P.

AU - Vedarethinam, I.

AU - Dimaki, Maria

PY - 2011/12/1

Y1 - 2011/12/1

N2 - In this paper some technological platforms developed for biological cell analysis will be presented and compared to existing systems. In brief, we present a novel micro cell culture chamber based on diffusion feeding of cells, into which cells can be introduced and extracted after culturing using normal pipettes, thus making it readily usable for clinical laboratories. To enhance the functionality of such a chamber we have been investigating the use of active or passive 3D surface modifications. Active modifications involve miniature electrodes able to record electrical or electrochemical signals from the cells, while passive modifications involve the presence of a peptide nanotube based scaffold for the cell culturing that mimics the in vivo environment. Two applications involving fluorescent in situ hybridization (FISH) analysis and cancer cell sorting are presented, as examples of further analysis that can be done after cell culturing. A platform able to automate the entire process from cell culturing to cell analysis by means of simple plug and play of various self-contained, individually fabricated modules is finally described.

AB - In this paper some technological platforms developed for biological cell analysis will be presented and compared to existing systems. In brief, we present a novel micro cell culture chamber based on diffusion feeding of cells, into which cells can be introduced and extracted after culturing using normal pipettes, thus making it readily usable for clinical laboratories. To enhance the functionality of such a chamber we have been investigating the use of active or passive 3D surface modifications. Active modifications involve miniature electrodes able to record electrical or electrochemical signals from the cells, while passive modifications involve the presence of a peptide nanotube based scaffold for the cell culturing that mimics the in vivo environment. Two applications involving fluorescent in situ hybridization (FISH) analysis and cancer cell sorting are presented, as examples of further analysis that can be done after cell culturing. A platform able to automate the entire process from cell culturing to cell analysis by means of simple plug and play of various self-contained, individually fabricated modules is finally described.

UR - http://www.scopus.com/inward/record.url?scp=82755191531&partnerID=8YFLogxK

U2 - 10.1016/j.sna.2011.02.027

DO - 10.1016/j.sna.2011.02.027

M3 - Journal article

AN - SCOPUS:82755191531

VL - 172

SP - 54

EP - 60

JO - Sensors and Actuators A: Physical

JF - Sensors and Actuators A: Physical

SN - 0924-4247

IS - 1

ER -

ID: 49847395