Safety and efficacy of a feed additive consisting of disodium 5'-inosinate (IMP) produced by Corynebacterium stationis KCCM 80235 for all animal species (CJ Europe GmbH)

Department of Veterinary and Animal Sciences

Research output: Contribution to journal › Journal article › Research

Standard

Safety and efficacy of a feed additive consisting of disodium 5'-inosinate (IMP) produced by Corynebacterium stationis KCCM 80235 for all animal species (CJ Europe GmbH). / EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP).

In: EFSA Journal, Vol. 20, No. 3, e07153, 2022.

Research output: Contribution to journal › Journal article › Research

Harvard

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) 2022, 'Safety and efficacy of a feed additive consisting of disodium 5'-inosinate (IMP) produced by Corynebacterium stationis KCCM 80235 for all animal species (CJ Europe GmbH)', EFSA Journal, vol. 20, no. 3, e07153. https://doi.org/10.2903/j.efsa.2022.7153

APA

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) (2022). Safety and efficacy of a feed additive consisting of disodium 5'-inosinate (IMP) produced by Corynebacterium stationis KCCM 80235 for all animal species (CJ Europe GmbH). EFSA Journal, 20(3), [e07153]. https://doi.org/10.2903/j.efsa.2022.7153

Vancouver

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). Safety and efficacy of a feed additive consisting of disodium 5'-inosinate (IMP) produced by Corynebacterium stationis KCCM 80235 for all animal species (CJ Europe GmbH). EFSA Journal. 2022;20(3). e07153. https://doi.org/10.2903/j.efsa.2022.7153

Author

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). / Safety and efficacy of a feed additive consisting of disodium 5'-inosinate (IMP) produced by Corynebacterium stationis KCCM 80235 for all animal species (CJ Europe GmbH). In: EFSA Journal. 2022 ; Vol. 20, No. 3.

Bibtex

@article{5f02fe935a2d44988961ef382f4337f9,

title = "Safety and efficacy of a feed additive consisting of disodium 5'-inosinate (IMP) produced by Corynebacterium stationis KCCM 80235 for all animal species (CJ Europe GmbH)",

abstract = "Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of disodium 5{\textquoteright}-inosinate (IMP) produced by fermentation using Corynebacterium stationis KCCM 80235 as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is genetically modified, and it is resistant to streptomycin. No viable cells were detected in the final product. However, uncertainties remained on the genetic basis of the streptomycin resistance and on the possible presence of recombinant DNA from the production strain in the final product. Therefore, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) could not conclude on the safety of the additive for the target species, consumers, users and the environment. Moreover, the FEEDAP Panel reiterated its previous concerns on the safety of the use of IMP in water for drinking due to hygienic reasons. The Panel concluded that the additive is efficacious to contribute to the flavour of feed and water for drinking.",

keywords = "all animal species, disodium 5{\textquoteright}-inosinate, efficacy, flavouring compounds, safety, Sensory",

author = "Vasileios Bampidis and Giovanna Azimonti and Bastos, {Maria de Lourdes} and Henrik Christensen and Birgit Dusemund and {Fa{\v s}mon Durjava}, Mojca and Maryline Kouba and Marta L{\'o}pez-Alonso and {L{\'o}pez Puente}, Secundino and Francesca Marcon and Baltasar Mayo and Alena Pechov{\'a} and Mariana Petkova and Fernando Ramos and Yolanda Sanz and Villa, {Roberto Edoardo} and Ruud Woutersen and Montserrat Anguita and Rosella Brozzi and Jaume Galobart and Paola Manini and Jordi Tarr{\'e}s-Call and Elisa Pettenati and {EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)}",

note = "Publisher Copyright: {\textcopyright} 2022 Wiley-VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety Authority.",

year = "2022",

doi = "10.2903/j.efsa.2022.7153",

language = "English",

volume = "20",

journal = "E F S A Journal",

issn = "1831-4732",

publisher = "European Food Safety Authority (E F S A)",

number = "3",

}

RIS

TY - JOUR

T1 - Safety and efficacy of a feed additive consisting of disodium 5'-inosinate (IMP) produced by Corynebacterium stationis KCCM 80235 for all animal species (CJ Europe GmbH)

AU - Bampidis, Vasileios

AU - Azimonti, Giovanna

AU - Bastos, Maria de Lourdes

AU - Christensen, Henrik

AU - Dusemund, Birgit

AU - Fašmon Durjava, Mojca

AU - Kouba, Maryline

AU - López-Alonso, Marta

AU - López Puente, Secundino

AU - Marcon, Francesca

AU - Mayo, Baltasar

AU - Pechová, Alena

AU - Petkova, Mariana

AU - Ramos, Fernando

AU - Sanz, Yolanda

AU - Villa, Roberto Edoardo

AU - Woutersen, Ruud

AU - Anguita, Montserrat

AU - Brozzi, Rosella

AU - Galobart, Jaume

AU - Manini, Paola

AU - Tarrés-Call, Jordi

AU - Pettenati, Elisa

AU - EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)

PY - 2022

Y1 - 2022

N2 - Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of disodium 5’-inosinate (IMP) produced by fermentation using Corynebacterium stationis KCCM 80235 as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is genetically modified, and it is resistant to streptomycin. No viable cells were detected in the final product. However, uncertainties remained on the genetic basis of the streptomycin resistance and on the possible presence of recombinant DNA from the production strain in the final product. Therefore, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) could not conclude on the safety of the additive for the target species, consumers, users and the environment. Moreover, the FEEDAP Panel reiterated its previous concerns on the safety of the use of IMP in water for drinking due to hygienic reasons. The Panel concluded that the additive is efficacious to contribute to the flavour of feed and water for drinking.

AB - Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of disodium 5’-inosinate (IMP) produced by fermentation using Corynebacterium stationis KCCM 80235 as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is genetically modified, and it is resistant to streptomycin. No viable cells were detected in the final product. However, uncertainties remained on the genetic basis of the streptomycin resistance and on the possible presence of recombinant DNA from the production strain in the final product. Therefore, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) could not conclude on the safety of the additive for the target species, consumers, users and the environment. Moreover, the FEEDAP Panel reiterated its previous concerns on the safety of the use of IMP in water for drinking due to hygienic reasons. The Panel concluded that the additive is efficacious to contribute to the flavour of feed and water for drinking.

KW - all animal species

KW - disodium 5’-inosinate

KW - efficacy

KW - flavouring compounds

KW - safety

KW - Sensory

U2 - 10.2903/j.efsa.2022.7153

DO - 10.2903/j.efsa.2022.7153

M3 - Journal article

C2 - 35281652

AN - SCOPUS:85127723874

VL - 20

JO - E F S A Journal

JF - E F S A Journal

SN - 1831-4732

IS - 3

M1 - e07153

ER -

ID: 320396495