Jan Gorodkin
Professor
- 2024
- E-pub ahead of print
Systematic analysis and characterization of long non-coding RNA genes in inflammatory bowel disease
Velissari, R., Ilieva, M., Dao, J., Miller, H. E., Madsen, J. H., Gorodkin, Jan, Aikawa, M., Ishii, H. & Uchida, S., 2024, (E-pub ahead of print) In: Briefings in Functional Genomics.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3
Haukedal, H., Syshøj Lorenzen, S., Westi, Emil Winther, Corsi, G., Gadekar, V. P., McQuade, A., Davtyan, H., Doncheva, Nadezhda Tsankova, Schmid, B., Chandrasekaran, Abinaya, Seemann, Ernst Stefan, Cirera, Susanna, Blurton-Jones, M., Meyer, M., Gorodkin, Jan, Aldana, Blanca & Freude, Kristine, 2023, In: Brain, Behavior, and Immunity. 113, p. 353-373Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CRISPRi screen for enhancing heterologous alpha-amylase yield in Bacillus subtilis
Geissler, Adrian Sven, Fehler, A. O., Poulsen, L. D., Gonzalez-Tortuero, E., Kallehauge, T. B., Alkan, F., Anthon, Christian, Seemann, Ernst Stefan, Rasmussen, M. D., Breuener, A., Hjort, C., Vinther, Jeppe & Gorodkin, Jan, 2023, In: Journal of Industrial Microbiology and Biotechnology. 50, 1, 16 p., kuac028.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis
Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Svane, C. A. S., Mirza, A. H., Litman, Thomas, Holmskov, U., Bang-Berthelsen, C. H., Vilien, M., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2023, In: Frontiers in Molecular Biosciences. 9, 1081176.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Golgi fragmentation: One of the earliest organelle phenotypes in Alzheimer's disease neurons
Haukedal, H., Corsi, G. I., Gadekar, V. P., Doncheva, N. T., Kedia, S., de Haan, N., Chandrasekaran, A., Jensen, P., Schiønning, P., Vallin, S., Marlet, F. R., Poon, A., Pires, C., Agha, F. K., Wandall, H. H., Cirera, S., Simonsen, A. H., Nielsen, T. T., Nielsen, J. E., Hyttel, P. & 7 others, , 2023, In: Frontiers in Neuroscience. 17, 17 p., 1120086.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Letter to the editor: Testing on external independent datasets is necessary to corroborate machine learning model improvement
Corsi, G. I., Anthon, Christian & Gorodkin, Jan, 2023, In: Bioinformatics. 39, 6, btad327.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi
Cavazza, A., Hendel, A., Bak, R. O., Rio, P., Güell, M., Lainšček, D., Arechavala-Gomeza, V., Peng, L., Hapil, F. Z., Harvey, J., Ortega, F. G., Gonzalez-Martinez, C., Lederer, C. W., Mikkelsen, K., Gasiunas, G., Kalter, N., Gonçalves, M. A. F. V., Petersen, J., Garanto, A., Montoliu, L. & 20 others, , 2023, In: Molecular Therapy Nucleic Acids. 34, 14 p., 102066.Research output: Contribution to journal › Review › Research › peer-review
- Published
RNA-Seq Study on the Longissimus thoracis Muscle of Italian Large White Pigs Fed Extruded Linseed with or without Antioxidants and Polyphenols
Vegni, J., Sun, Y., Seemann, Ernst Stefan, Zappaterra, M., Davoli, R., Dall’Olio, S., Gorodkin, Jan & Zambonelli, P., 2023, In: Animals. 13, 7, 1187.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression
Corsi, G. I., Gadekar, V. P., Haukedal, H., Doncheva, Nadezhda Tsankova, Anthon, Christian, Ambardar, S., Palakodeti, D., Hyttel, P., Freude, Kristine, Seemann, Ernst Stefan & Gorodkin, Jan, 2023, In: Neurobiology of Disease. 178, 17 p., 105980.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Translational control of furina by an RNA regulon is important for left-right patterning, heart morphogenesis and cardiac valve function
Nagorska, A., Zaucker, A., Lambert, F., Inman, A., Toral-Perez, S., Gorodkin, Jan, Wan, Y., Smutny, M. & Sampath, K., 2023, In: Development (Cambridge). 150, 23, 15 p., 201657.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utilizing directed evolution to interrogate and optimize CRISPR/Cas guide RNA scaffolds
Bush, K., Corsi, G. I., Yan, A. C., Haynes, K., Layzer, J. M., Zhou, J. H., Llanga, T., Gorodkin, Jan & Sullenger, B. A., 2023, In: Cell Chemical Biology. 30, 8, p. 879-892.e5Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Single cell mapping the evolution of the spatial processing centre within the brain
Ralbovszki, Dorottya Maria, Bertelsen, Mads Frost, Buchmann, Kurt, Mori, Yuki, Gorodkin, Jan, Hemberg, M., Seemann, Ernst Stefan, Khodosevich, Konstantin & Hall, Vanessa Jane, 1 May 2022.Research output: Contribution to conference › Poster › Communication
- Published
CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context
Corsi, G. I., Qu, Kunli, Alkan, F., Pan, Xiaoguang, Luo, Y. & Gorodkin, Jan, 2022, In: Nature Communications. 13, 14 p., 3006.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CRISPRon/off: CRISPR/Cas9 on- and off-target gRNA design
Anthon, Christian, Corsi, G. I. & Gorodkin, Jan, 2022, In: Bioinformatics. 38, 24, p. 5437-5439 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CRISPRroots: On-and off-target assessment of RNA-seq data in CRISPR-Cas9 edited cells
Corsi, G. I., Gadekar, V. P., Gorodkin, Jan & Seemann, Ernst Stefan, 2022, In: Nucleic Acids Research. 50, 4, 12 p., E20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differentially Expressed miRNAs in Ulcerative Colitis and Crohn's Disease
Yarani, R., Shojaeian, A., Palasca, Oana, Doncheva, Nadezhda Tsankova, Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2022, In: Frontiers in Immunology. 13, 21 p., 865777.Research output: Contribution to journal › Review › Research › peer-review
- Published
Does rapid sequence divergence preclude RNA structure conservation in vertebrates?
Seemann, Ernst Stefan, Mirza, A. H., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Workman, C. T., Pociot, Flemming, Tommerup, Niels, Gorodkin, Jan & Ruzzo, W. L., 2022, In: Nucleic Acids Research. 50, 5, p. 2452-2463 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flagella disruption in Bacillus subtilis increases amylase production yield
Fehler, A. O., Kallehauge, T. B., Geissler, Adrian Sven, González-Tortuero, E., Seemann, Ernst Stefan, Gorodkin, Jan & Vinther, Jeppe, 2022, In: Microbial Cell Factories. 21, 11 p., 131.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Massively targeted evaluation of therapeutic CRISPR off-targets in cells
Pan, X., Qu, K., Yuan, H., Xiang, X., Anthon, C., Pashkova, L., Liang, X., Han, P., Corsi, G. I., Xu, F., Liu, P., Zhong, J., Zhou, Y., Ma, T., Jiang, H., Liu, J., Wang, J., Jessen, N., Bolund, L., Yang, H. & 5 others, , 2022, In: Nature Communications. 13, 14 p., 4049.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming
Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, , 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Bacillaceae-1 RNA motif comprises two distinct classes
González-Tortuero, E., Anthon, Christian, Havgaard, Jakob Hull, Geissler, Adrian Sven, Breüner, A., Hjort, C., Gorodkin, Jan & Seemann, Ernst Stefan, 2022, In: Gene. 841, 146756.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of PrsA over-expression on the Bacillus subtilis transcriptome during fed-batch fermentation of alpha-amylase production
Geissler, Adrian Sven, Poulsen, L. D., Doncheva, Nadezhda Tsankova, Anthon, Christian, Seemann, Ernst Stefan, González-Tortuero, E., Breüner, A., Jensen, Lars Juhl, Hjort, C., Vinther, Jeppe & Gorodkin, Jan, 2022, In: Frontiers in Microbiology. 13, 17 p., 909493.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
A non-enzymatic, isothermal strand displacement and amplification assay for rapid detection of SARS-CoV-2 RNA
Mohammadniaei, M., Zhang, M., Ashley, J., Christensen, U. B., Friis-Hansen, L. J., Gregersen, R., Lisby, J. G., Benfield, Thomas, Nielsen, F. E., Henning Rasmussen, J., Pedersen, E. B., Olinger, A. C. R., Kolding, L. T., Naseri, M., Zheng, T., Wang, W., Gorodkin, Jan & Sun, Y., 2021, In: Nature Communications. 12, 5089.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3
Chandrasekaran, A., Dittlau, K. S., Corsi, G. I., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Zhang, Y., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J. E., Kolko, M., Kobolák, J., Dinnyés, A., Hyttel, P., Palakodeti, D. & 5 others, , 2021, In: Stem Cell Reports. 16, 11, p. 2736-2751Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bsgatlas: A unified bacillus subtilis genome and transcriptome annotation atlas with enhanced information access
Geissler, Adrian Sven, Anthon, Christian, Alkan, F., González-Tortuero, E., Poulsen, L. D., Kallehauge, T. B., Breüner, A., Seemann, Ernst Stefan, Vinther, Jeppe & Gorodkin, Jan, 2021, In: Microbial Genomics. 7, 2, 17 p., 000524.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of the entorhinal cortex occurs via parallel lamination during neurogenesis
Liu, Y., Bergmann, T., Mori, Yuki, Peralvo Vidal, Juan Miguel, Pihl, M., Vasistha, Navneet A, Thomsen, Preben Dybdahl, Seemann, Ernst Stefan, Gorodkin, Jan, Hyttel, P., Khodosevich, Konstantin, Witter, M. P. & Hall, Vanessa Jane, 2021, In: Frontiers in Neuroanatomy. 15, 19 p., 663667.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning
Xiang, X., Corsi, G. I., Anthon, C., Qu, K., Pan, X., Liang, X., Han, P., Dong, Z., Liu, L., Zhong, J., Ma, T., Wang, J., Zhang, X., Jiang, H., Xu, F., Liu, X., Xu, X., Wang, J., Yang, H., Bolund, L. & 4 others, , 2021, In: Nature Communications. 12, 1, 9 p., 3238.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human pathways in animal models: possibilities and limitations
Doncheva, Nadezhda Tsankova, Palasca, Oana, Yarani, R., Litman, Thomas, Anthon, Christian, Groenen, M. A. M., Stadler, P. F., Pociot, Flemming, Jensen, Lars Juhl & Gorodkin, Jan, 2021, In: Nucleic Acids Research. 49, 4, p. 1859-1871 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel circRNA discovery in sheep shows evidence of high backsplice junction conservation
Varela-Martínez, E., Corsi, G. I., Anthon, Christian, Gorodkin, Jan & Jugo, B. M., 2021, In: Scientific Reports. 11, 1, 11 p., 427.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNAcentral 2021: Secondary structure integration, improved sequence search and new member databases
Sweeney, B. A., Petrov, A. I., Ribas, C. E., Finn, R. D., Bateman, A., Szymanski, M., Karlowski, W. M., Seemann, S. E., Gorodkin, J., Cannone, J. J., Gutell, R. R., Kay, S., Marygold, S., Dos Santos, G., Frankish, A., Mudge, J. M., Barshir, R., Fishilevich, S., Chan, P. P., Lowe, T. M. & 26 others, , 2021, In: Nucleic Acids Research. 49, D1, p. D212-D220Research output: Contribution to journal › Journal article › Research › peer-review
- Published
iPSC-derived Microglia for Disease Modeling of Frontotemporal Dementia 3
Haukedal, H., Freude, Kristine, Garcia, B. A., Corsi, G., Gadekar, V. & Gorodkin, Jan, 2021, In: Glia. 69, S1, p. E480-E481 T14-066D.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- 2020
- Published
Patient iPSC-Derived Neorons for Disease Modeling of Familiar Alzheimer's Disease with Mutations in Presenilin 1
Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, Oct 2020.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a
Creutzburg, S. C. A., Wu, W. Y., Mohanraju, P., Swartjes, T., Alkan, F., Gorodkin, Jan, Staals, R. H. J. & van der Oost, J., 2020, In: Nucleic Acids Research. 48, 6, p. 3228-3243 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation in FTD3 CHMP2B causes impaired autography and distorted energy metabolism cumulating in reactive astrocyte phenotypes
Chandrasekaran, A., Dittlau, K. S., Corsi, G., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, , 2020.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Mutations in FTD3 CHMP2B causes impaired autophagy and distorted energy metabolism cumulating in reactive astrocyte phenotypes
Chandrasekaran, A., Dittlau, K. S., Corsi, G., Doncheva, N. T., Haukedal, H., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, , 2020.Research output: Contribution to conference › Poster › Research
- Published
Using GPU to accelerate the pairwise structural RNA alignment with base pair probabilities
Sundfeld, D., Teodoro, G., Havgaard, Jakob Hull, Gorodkin, Jan & Melo, A. C. M. A., 2020, In: Concurrency Computation. 32, 10, e5468.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
The developing Entorhinal cortex - a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 25 Nov 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
Patient iPSC-Derived Neurons for Disease Modeling of Familiar Alzheier's Disease with Mutations in Presenilin 1
Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, 26 Mar 2019.Research output: Contribution to conference › Poster › Communication
- Published
A splice-site variant in the lncRNA gene RP1-140A9.1 cosegregates in the large Volkmann cataract family
Eiberg, Hans Rudolf Lytchoff, Mikkelsen, Annemette Friis, Bak, M., Tommerup, Niels, Lund, A. M., Wenzel, Anne, Sabarinathan, R., Gorodkin, Jan, Bang-Berthelsen, C. H. & Hansen, Lars, 2019, In: Molecular Vision. 25, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytoscape stringApp: Network analysis and visualization of proteomics data
Doncheva, Nadezhda Tsankova, Morris, J., Gorodkin, Jan & Jensen, Lars Juhl, 2019, In: Journal of Proteome Research. 18, 2, p. 623-632Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism
Jacobsen, M. J., Havgaard, Jakob Hull, Anthon, Christian, Mentzel, Caroline M. Junker, Cirera, Susanna, Krogh, P. M., Pundhir, Sachin, Karlskov-Mortensen, Peter, Bruun, C. S., Lesnik, P., Guerin, M., Gorodkin, Jan, Jørgensen, Claus Bøttcher, Fredholm, Merete & Barrès, Romain, 2019, In: Frontiers in Genetics. 10, 13 p., 1268.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inferring disease-associated long non-coding RNAs using genome - wide tissue expression profiles
Pan, X., Jensen, Lars Juhl & Gorodkin, Jan, 2019, In: Bioinformatics. 35, 9, p. 1494-1502 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of stellate cells from induced pluripotent stem cells to study Alzheimer's disease pathology
Mogus, L., Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
RNAcentral: a hub of information for non-coding RNA sequences
The RNAcentral Constortium , T., Gorodkin, Jan & Seemann, Ernst Stefan, 2019, In: Nucleic Acids Research. 47, D1, p. D221–D229Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sandwich cortial lamination and single-cell analysis decodes the developing spatial processing system
Liu, Y., Bergmann, T. B., Lee, J., Pfisterer, U. G., Handfield, L-F., Mori, Y., Asenjo Martinez, A., Lisa Vargas, I., Seemann, E. S., Lee, J. T. H., Patikis, N., Peralvo Vidal, J. M., Pihl, M., Kornum, B. R., Thomsen, P. D., Hyttel, P., Witter, M., Khodosevich, K., Gorodkin, J., Hemberg, M. & 2 others, , 2019. 45 p.Research output: Contribution to conference › Paper › Communication
- Published
Special issue: Computational analysis of RNA structure and function
Gorodkin, Jan, 2019, In: Genes. 10, 1, 3 p., 55.Research output: Contribution to journal › Editorial › Research
- Published
The developing Entorhinal Cortex – a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Transcriptome landscape of protein-coding genes and long noncoding RNAs in the colon and blood of DSS-induced mouse model of Acute ulcerative colitis
Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Litman, Thomas, Holmskov, U., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2019, In: Journal of Crohn's and Colitis. 13, p. S129-S130Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Uncovering the anatomical and molecular landscape of the starting point of Alzheimer’s disease in the brain
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
- 2018
- Published
Multiple Sequence Alignments Enhance Boundary Definition of RNA Structures
Sabarinathan, R., Anthon, Christian, Gorodkin, Jan & Seemann, Ernst Stefan, 4 Dec 2018, In: Genes. 9, 12, 17 p., 604.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA.
Pan, X., Xiong, K., Anthon, Christian, Hyttel, P., Freude, Kristine, Jensen, Lars Juhl & Gorodkin, Jan, 6 Nov 2018, In: Genes. 9, 11, 11 p., 536.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Translational co-regulation of a ligand and inhibitor by a conserved RNA element
Zaucker, A., Nagorska, A., Kumari, P., Hecker, N., Wang, Y., Huang, S., Cooper, L., Sivashanmugam, L., VijayKumar, S., Brosens, J., Gorodkin, Jan & Sampath, K., Jan 2018, In: Nucleic Acids Research. 46, 1, p. 104–119Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CRISPR-Cas9 off-targeting assessment with nucleic acid duplex energy parameters
Alkan, F., Wenzel, Anne, Anthon, Christian, Havgaard, Jakob Hull & Gorodkin, Jan, 2018, In: Genome Biology. 19, 13 p., 177.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative RNA genomics
Backofen, R., Gorodkin, Jan, Hofacker, I. L. & Stadler, P. F., 2018, Comparative Genomics: Methods and Protocols. Humana Press, Vol. 1704. p. 363-400 38 p. (Methods in Molecular Biology, Vol. 1704).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Genome-wide identification of clusters of predicted microRNA binding sites as microRNA sponge candidates
Pan, X., Wenzel, Anne, Jensen, Lars Juhl & Gorodkin, Jan, 2018, In: PLoS ONE. 13, 8, 15 p., e0202369.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IFN-λ and microRNAs are important modulators of the pulmonary innate immune response against influenza A (H1N2) infection in pigs
Brogaard, L., Larsen, Lars, Heegaard, P. M. H., Anthon, Christian, Gorodkin, Jan, Dürrwald, R. & Skovgaard, K., 2018, In: PLOS ONE. 13, 4, 23 p., e0194765.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of novel conserved RNA structures in Drosophila
Kirsch, Rebecca, Seemann, Ernst Stefan, Ruzzo, W. L., Cohen, S. M., Stadler, P. F. & Gorodkin, Jan, 2018, In: BMC Genomics. 19, 20 p., 899.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TISSUES 2.0: an integrative web resource on mammalian tissue expression
Palasca, Oana, Santos, A., Stolte, C., Gorodkin, Jan & Jensen, Lars Juhl, 2018, In: Database: The Journal of Biological Databases and Curation. 2018, 1, p. 1-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.
Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.
Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer
Eichenlaub, T., Villadsen, René, Freitas, F. C. P., Andrejeva, Diana, Aldana, Blanca, Nguyen, H. T., Petersen, Ole William, Gorodkin, Jan, Herranz, Hector & Cohen, S. M., 2018, In: Current Biology. 28, 20, p. 3220-3228.e6Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Alignment-free comparative genomic screen for structured RNAs using coarse-grained secondary structure dot plots
Kato, Y., Gorodkin, Jan & Havgaard, Jakob Hull, Dec 2017, In: BMC Genomics. 18, 1, 935.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing the miRNA sponge potential of RUNX1T1 in t(8;21) acute myeloid leukemia
Junge, A., Zandi, R., Havgaard, Jakob Hull, Gorodkin, Jan & Cowland, J. B., 2017, In: Gene. 615, p. 35-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associating transcription factors and conserved RNA structures with gene regulation in the human brain
Hecker, N., Seemann, Ernst Stefan, Silahtaroglu, Asli, Ruzzo, W. L. & Gorodkin, Jan, 2017, In: Scientific Reports. 7, 1, 16 p., 5776.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CUDA-Sankoff: Using GPU to Accelerate the Pairwise Structural RNA Alignment
Sundfeld, D., Havgaard, Jakob Hull, Gorodkin, Jan & De Melo, A. C. M. A., 2017, Proceedings: 2017 25th Euromicro International Conference on Parallel, Distributed and Network-Based Processing, PDP 2017. IEEE, p. 295-302 8 p. 7912663Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
RAIN: RNA-protein Association and Interaction Networks
Junge, A., Refsgaard, J. C., Garde, C., Pan, X., Santos, A., Alkan, F., Anthon, Christian, von Mering, C., Workman, C. T., Jensen, Lars Juhl & Gorodkin, Jan, 2017, In: Database: The Journal of Biological Databases and Curation. 2017, 9 p., baw167.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RIsearch2: suffix array-based large-scale prediction of RNA-RNA interactions and siRNA off-targets
Alkan, F., Wenzel, Anne, Palasca, Oana, Kerpedjiev, P., Rudebeck, A. F., Stadler, P. F., Hofacker, I. L. & Gorodkin, Jan, 2017, In: Nucleic Acids Research. 45, 8, 13 p., e60.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNAscClust: Clustering RNA sequences using structure conservation and graph based motifs
Miladi, M., Junge, A., Costa, F., Seemann, Ernst Stefan, Havgaard, Jakob Hull, Gorodkin, Jan & Backofen, R., 2017, In: Bioinformatics. 33, 14, p. 2089-2096 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The identification and functional annotation of RNA structures conserved in vertebrates
Seemann, Ernst Stefan, Mirza, A. H., Hansen, C., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Torarinsson, E., Yao, Z., Workman, C. T., Pociot, Flemming, Nielsen, Henrik, Tommerup, Niels, Ruzzo, W. L. & Gorodkin, Jan, 2017, In: Genome Research. 27, p. 1371-1383 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Joint profiling of miRNAs and mRNAs reveals miRNA mediated gene regulation in the Göttingen minipig obesity model
Mentzel, Caroline M. Junker, Alkan, F., Keinicke, H., Jacobsen, M. J., Gorodkin, Jan, Fredholm, Merete & Cirera, Susanna, 30 Nov 2016, In: P L o S One. 11, 11, 16 p., e0167285.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipocyte gene expression and DNA methylation patterns differ significantly between lean and obese pigs
Jacobsen, M. J., Havgaard, Jakob Hull, Mentzel, Caroline M. Junker, Sørensen, P. M., Pundhir, Sachin, Anthon, Christian, Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Gorodkin, Jan, Jørgensen, Claus Bøttcher, Barrès, Romain & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement 4, p. 46-47 2 p., P2019.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells: [Plus] Corrigendum
Hölzer, M., Krähling, V., Amman, F., Barth, E., Bernhart, S. H., Carmelo, V. A. O., Collatz, M., Doose, G., Eggenhofer, F., Ewald, J., Fallmann, J., Feldhahn, L. M., Fricke, M., Gebauer, J., Gruber, A. J., Hufsky, F., Indrischek, H., Kanton, S., Linde, J., Mostajo, N. & 19 others, , 7 Oct 2016, In: Scientific Reports. 6, 16 p., 34589.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foldalign 2.5: multithreaded implementation for pairwise structural RNA alignment
Sundfeld, D., Havgaard, Jakob Hull, de Melo, A. C. M. A. & Gorodkin, Jan, 2016, In: Bioinformatics. 32, 8, p. 1238-1240 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Full-length RNA structure prediction of the HIV-1 genome reveals a conserved core domain
Sükösd, Z., Andersen, E. S., Seemann, Ernst Stefan, Jensen, M. K., Hansen, M., Gorodkin, Jan & Kjems, J., 2 Dec 2015, In: Nucleic Acids Research. 43, 21, p. 10168-79 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gender and obesity specific MicroRNA expression in adipose tissue from lean and obese pigs
Mentzel, Caroline M. Junker, Anthon, Christian, Jacobsen, M. J., Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Jørgensen, Claus Bøttcher, Gorodkin, Jan, Cirera, Susanna & Fredholm, Merete, 29 Jul 2015, In: P L o S One. 10, 7, 19 p., e0131650.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential and coherent processing patterns from small RNAs
Pundhir, Sachin & Gorodkin, Jan, 13 Jul 2015, In: Scientific Reports. 5, 16 p., 12062.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous DNA and RNA mapping of somatic mitochondrial mutations across diverse human cancers
Stewart, J. B., Alaei-Mahabadi, B., Radhakrishnan, S., Samuelsson, T., Gorodkin, Jan, Gustafsson, C. M. & Larsson, E., Jun 2015, In: P L o S Genetics. 11, 6, 15 p., e1005333.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emerging applications of read profiles towards the functional annotation of the genome
Pundhir, Sachin, Poirazi, P. & Gorodkin, Jan, 19 May 2015, In: Frontiers in Genetics. 6, 11 p., 188.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Profiling of Ribose Methylations in RNA by High-Throughput Sequencing
Birkedal, U., Christensen-Dalsgaard, M., Krogh, Nicolai, Radhakrishnan, S., Gorodkin, Jan & Nielsen, Henrik, 7 Jan 2015, In: Angewandte Chemie (International ed. in English). 54, 2, p. 451-455 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emerging tools for RNA structure analysis in polymorphic data
Radhakrishnan, S., Seemann, Ernst Stefan & Gorodkin, Jan, 2015, In: Biozoom. 2, p. 10-13 4 p.Research output: Contribution to journal › Journal article › Communication
- Published
Optimizing RNA structures by sequence extensions using RNAcop
Hecker, N., Christensen-Dalsgaard, M., Seemann, Ernst Stefan, Havgaard, Jakob Hull, Stadler, P. F., Hofacker, I. L., Nielsen, Henrik & Gorodkin, Jan, 2015, In: Nucleic Acids Research. 43, 17, p. 8135-8145 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quality Assessment of Domesticated Animal Genome Assemblies
Seemann, Ernst Stefan, Anthon, Christian, Palasca, Oana & Gorodkin, Jan, 2015, In: Bioinformatics and Biology Insights. 9, Suppl 4, p. 49-58 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA 3D modules in genome-wide predictions of RNA 2D structure
Theis, C., Zirbel, C. L., Zu Siederdissen, C. H., Anthon, Christian, Hofacker, I. L., Nielsen, Henrik & Gorodkin, Jan, 2015, In: PLOS ONE. 10, 10, 13 p., e0139900.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic landscape of lncRNAs in inflammatory bowel disease
Mirza, A. H., Bang-Berthelsen, C. H., Seemann, Ernst Stefan, Pan, X., Frederiksen, K. S., Vilien, M., Gorodkin, Jan & Pociot, Flemming, 2015, In: Genome Medicine. 7, 22 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Spatially conserved regulatory elements identified within human and mouse Cd247 gene using high-throughput sequencing data from the ENCODE project.
Pundhir, Sachin, Hannibal, T. D., Bang-Berthelsen, C. H., Wegener, A. K., Pociot, Flemming, Holmberg, D. I. & Gorodkin, Jan, 2 May 2014, In: Gene. 545, 1, p. 80-87 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
De Novo Discovery of Structured ncRNA Motifs in Genomic Sequences
Ruzzo, W. L. & Gorodkin, Jan, 2014, RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods. Gorodkin, J. & Ruzzo, W. L. (eds.). Vol. 1097. p. 303-18 16 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Computational approaches for predicting mutation effects on RNA Sstructure
Radhakrishnan, S. & Gorodkin, Jan, 2014, Bioinformatics. Persson, B. (ed.). Elsevier, p. 111-121 11 p. (Comprehensive biomedical physics, Vol. 6).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Concepts and introduction to RNA bioinformatics
Gorodkin, Jan, Hofacker, I. L. & Ruzzo, W. L., 2014, In: Methods in molecular biology (Clifton, N.J.). 1097, p. 1-31 31 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein-driven inference of miRNA-disease associations
Mørk, S., Pletscher-Frankild, S., Palleja, A., Gorodkin, Jan & Jensen, Lars Juhl, 2014, In: Bioinformatics (Oxford, England). 30, 3, p. 392-397 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA Structural Alignments, Part I: Sankoff-Based Approaches for Structural Alignments
Havgaard, Jakob Hull & Gorodkin, Jan, 2014, RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods. Gorodkin, J. & Ruzzo, W. L. (eds.). p. 275-90 16 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Structured RNAs and synteny regions in the pig genome
Anthon, Christian, Tafer, H., Havgaard, Jakob Hull, Thomsen, B., Hedegaard, J., Seemann, Ernst Stefan, Pundhir, Sachin, Kehr, S., Bartschat, S., Nielsen, M., Nielsen, R. O., Fredholm, Merete, Stadler, P. F. & Gorodkin, Jan, 2014, In: BMC Genomics. 15, 27 p., 459.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome-wide analysis of UTRs in non-small cell lung cancer reveals cancer-related genes with SNV-induced changes on RNA secondary structure and miRNA target sites
Radhakrishnan, S., Wenzel, Anne, Novotny, P., Tang, X., Kalari, K. R. & Gorodkin, Jan, 2014, In: P L o S One. 9, 1, 16 p., e82699.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Discovery of a divergent HPIV4 from respiratory secretions using second and third generation metagenomic sequencing
Alquezar Planas, D. E., Mourier, T., Bruhn, C. A. W., Hansen, Anders Johannes, Vitcetz, S. N., Mørk, S., Gorodkin, Jan, Nielsen, H. A., Guo, Y., Sethuraman, A., Paxinos, E. E., Shan, T., Delwart, E. L. & Nielsen, L. P., 3 Sep 2013, In: Scientific Reports. 3, 10 p., 2468.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Automated identification of RNA 3D modules with discriminative power in RNA structural alignments
Theis, C., Höner zu Siederdissen, C., Hofacker, I. L. & Gorodkin, Jan, 2013, In: Nucleic Acids Research. 41, 22, p. 9999-10009 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global Analysis of Genetic and Epigenetic differences associated with Obesity
Jacobsen, M. J., Mentzel, Caroline M. Junker, Kogelman, L., Mark, T., Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Gorodkin, Jan, Kadarmideen, H., Barrès, Romain, Jørgensen, Claus Bøttcher & Fredholm, Merete, 2013.Research output: Contribution to conference › Poster › Research › peer-review
- Published
RNAsnp: efficient detection of local RNA secondary structure changes induced by SNPs: efficient detection of local RNA secondary structure changes induced by SNPs
Radhakrishnan, S., Tafer, H., Seemann, Ernst Stefan, Hofacker, I. L., Stadler, P. F. & Gorodkin, Jan, 2013, In: Human Mutation. 34, 4, p. 546-556 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The RNAsnp web server: predicting SNP effects on local RNA secondary structure
Radhakrishnan, S., Tafer, H., Seemann, Ernst Stefan, Hofacker, I. L., Stadler, P. F. & Gorodkin, Jan, 2013, In: Nucleic Acids Research. 41, p. W475-W479 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Profiling microRNAs in lung tissue from pigs infected with Actinobacillus pleuropneumoniae
Podolska, A., Anthon, Christian, Bak, M., Tommerup, Niels, Skovgaard, K., Heegaard, P. M., Gorodkin, Jan, Cirera, S. & Fredholm, Merete, Sep 2012, In: B M C Genomics. 13, 1, p. 459Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence and expression analysis of gaps in human chromosome 20
Minocherhomji, S., Seemann, Ernst Stefan, Mang, Y., Elschich, Z., Bak, M., Hansen, C., Papadopoulos, N., Josefsen, K., Nielsen, Henrik, Gorodkin, Jan, Tommerup, Niels & Silahtaroglu, Asli, Aug 2012, In: Nucleic Acids Research. 40, 14, p. 6660-6672 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analyses of pig genomes provide insight into porcine demography and evolution
Groenen, M. A., Archibald, A. L., Uenishi, H., Tuggle, C. K., Takeuchi, Y., Rothschild, M. F., Rogel-Gaillard, C., Park, C., Milan, D., Megens, H-J., Li, S., Larkin, D. M., Kim, H., Frantz, L. A. F., Caccamo, M., Ahn, H., Aken, B. L., Anselmo, A., Anthon, C., Auvil, L. & 116 others, , 2012, In: Nature. 491, 7424, p. 393-398 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4356276
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Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
Research output: Contribution to journal › Journal article › Research › peer-review
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1377
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454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides
Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptome-wide analysis of UTRs in non-small cell lung cancer reveals cancer-related genes with SNV-induced changes on RNA secondary structure and miRNA target sites
Research output: Contribution to journal › Journal article › Research › peer-review
Published