Diet-microbiota crosstalk and immunity to helminth infection

Research output: Contribution to journal › Review › Research › peer-review

Standard

Diet-microbiota crosstalk and immunity to helminth infection. / Myhill, Laura J.; Williams, Andrew R.

In: Parasite Immunology, Vol. 45, No. 4, 12965, 2023.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Myhill, LJ & Williams, AR 2023, 'Diet-microbiota crosstalk and immunity to helminth infection', Parasite Immunology, vol. 45, no. 4, 12965. https://doi.org/10.1111/pim.12965

APA

Myhill, L. J., & Williams, A. R. (2023). Diet-microbiota crosstalk and immunity to helminth infection. Parasite Immunology, 45(4), [12965]. https://doi.org/10.1111/pim.12965

Vancouver

Myhill LJ, Williams AR. Diet-microbiota crosstalk and immunity to helminth infection. Parasite Immunology. 2023;45(4). 12965. https://doi.org/10.1111/pim.12965

Author

Myhill, Laura J. ; Williams, Andrew R. / Diet-microbiota crosstalk and immunity to helminth infection. In: Parasite Immunology. 2023 ; Vol. 45, No. 4.

Bibtex

@article{1d9fce47c64e4bcc84a99ddbdee01f32,
title = "Diet-microbiota crosstalk and immunity to helminth infection",
abstract = "Helminths are large multicellular parasites responsible for widespread chronic disease in humans and animals. Intestinal helminths live in close proximity with the host gut microbiota and mucosal immune network, resulting in reciprocal interactions that closely influence the course of infections. Diet composition may strongly regulate gut microbiota composition and intestinal immune function and therefore may play a key role in modulating anti-helminth immune responses. Characterizing the multitude of interactions that exist between different dietary components (e.g., dietary fibres), immune cells, and the microbiota, may shed new light on regulation of helminth-specific immunity. This review focuses on the current knowledge of how metabolism of dietary components shapes immune response during helminth infection, and how this information may be potentially harnessed to design new therapeutics to manage parasitic infections and associated diseases.",
keywords = "immune modulation, immunological terms, mucosal immunity",
author = "Myhill, {Laura J.} and Williams, {Andrew R.}",
note = "Publisher Copyright: {\textcopyright} 2022 The Authors. Parasite Immunology published by John Wiley & Sons Ltd.",
year = "2023",
doi = "10.1111/pim.12965",
language = "English",
volume = "45",
journal = "Parasite Immunology",
issn = "0141-9838",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Diet-microbiota crosstalk and immunity to helminth infection

AU - Myhill, Laura J.

AU - Williams, Andrew R.

N1 - Publisher Copyright: © 2022 The Authors. Parasite Immunology published by John Wiley & Sons Ltd.

PY - 2023

Y1 - 2023

N2 - Helminths are large multicellular parasites responsible for widespread chronic disease in humans and animals. Intestinal helminths live in close proximity with the host gut microbiota and mucosal immune network, resulting in reciprocal interactions that closely influence the course of infections. Diet composition may strongly regulate gut microbiota composition and intestinal immune function and therefore may play a key role in modulating anti-helminth immune responses. Characterizing the multitude of interactions that exist between different dietary components (e.g., dietary fibres), immune cells, and the microbiota, may shed new light on regulation of helminth-specific immunity. This review focuses on the current knowledge of how metabolism of dietary components shapes immune response during helminth infection, and how this information may be potentially harnessed to design new therapeutics to manage parasitic infections and associated diseases.

AB - Helminths are large multicellular parasites responsible for widespread chronic disease in humans and animals. Intestinal helminths live in close proximity with the host gut microbiota and mucosal immune network, resulting in reciprocal interactions that closely influence the course of infections. Diet composition may strongly regulate gut microbiota composition and intestinal immune function and therefore may play a key role in modulating anti-helminth immune responses. Characterizing the multitude of interactions that exist between different dietary components (e.g., dietary fibres), immune cells, and the microbiota, may shed new light on regulation of helminth-specific immunity. This review focuses on the current knowledge of how metabolism of dietary components shapes immune response during helminth infection, and how this information may be potentially harnessed to design new therapeutics to manage parasitic infections and associated diseases.

KW - immune modulation

KW - immunological terms

KW - mucosal immunity

U2 - 10.1111/pim.12965

DO - 10.1111/pim.12965

M3 - Review

C2 - 36571323

AN - SCOPUS:85146295955

VL - 45

JO - Parasite Immunology

JF - Parasite Immunology

SN - 0141-9838

IS - 4

M1 - 12965

ER -

ID: 334261163