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Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe. / Sheehy, Susanne H; Spencer, Alexandra J; Douglas, Alexander D; Sim, B Kim Lee; Longley, Rhea J; Edwards, Nick J; Poulton, Ian D; Kimani, Domtila; Williams, Andrew Richard; Anagnostou, Nicholas A; Roberts, Rachel; Kerridge, Simon; Voysey, Merryn; James, Eric R; Billingsley, Peter F; Gunasekera, Anusha; Lawrie, Alison M; Hoffman, Stephen L; Hill, Adrian V S.
In:
PLOS ONE, Vol. 8, No. 6, 2013, p. e65960.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Sheehy, SH, Spencer, AJ, Douglas, AD, Sim, BKL, Longley, RJ, Edwards, NJ, Poulton, ID, Kimani, D
, Williams, AR, Anagnostou, NA, Roberts, R, Kerridge, S, Voysey, M, James, ER, Billingsley, PF, Gunasekera, A, Lawrie, AM, Hoffman, SL & Hill, AVS 2013, '
Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe',
PLOS ONE, vol. 8, no. 6, pp. e65960.
https://doi.org/10.1371/journal.pone.0065960APA
Sheehy, S. H., Spencer, A. J., Douglas, A. D., Sim, B. K. L., Longley, R. J., Edwards, N. J., Poulton, I. D., Kimani, D.
, Williams, A. R., Anagnostou, N. A., Roberts, R., Kerridge, S., Voysey, M., James, E. R., Billingsley, P. F., Gunasekera, A., Lawrie, A. M., Hoffman, S. L., & Hill, A. V. S. (2013).
Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe.
PLOS ONE,
8(6), e65960.
https://doi.org/10.1371/journal.pone.0065960Vancouver
Sheehy SH, Spencer AJ, Douglas AD, Sim BKL, Longley RJ, Edwards NJ et al.
Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe.
PLOS ONE. 2013;8(6):e65960.
https://doi.org/10.1371/journal.pone.0065960Author
Sheehy, Susanne H ; Spencer, Alexandra J ; Douglas, Alexander D ; Sim, B Kim Lee ; Longley, Rhea J ; Edwards, Nick J ; Poulton, Ian D ; Kimani, Domtila ; Williams, Andrew Richard ; Anagnostou, Nicholas A ; Roberts, Rachel ; Kerridge, Simon ; Voysey, Merryn ; James, Eric R ; Billingsley, Peter F ; Gunasekera, Anusha ; Lawrie, Alison M ; Hoffman, Stephen L ; Hill, Adrian V S. / Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe. In: PLOS ONE. 2013 ; Vol. 8, No. 6. pp. e65960.
Bibtex
@article{658d6d08a07849acbbfee072a713fc02,
title = "Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe",
abstract = "Controlled human malaria infection (CHMI) studies have become a routine tool to evaluate efficacy of candidate anti-malarial drugs and vaccines. To date, CHMI trials have mostly been conducted using the bite of infected mosquitoes, restricting the number of trial sites that can perform CHMI studies. Aseptic, cryopreserved P. falciparum sporozoites (PfSPZ Challenge) provide a potentially more accurate, reproducible and practical alternative, allowing a known number of sporozoites to be administered simply by injection.",
author = "Sheehy, {Susanne H} and Spencer, {Alexandra J} and Douglas, {Alexander D} and Sim, {B Kim Lee} and Longley, {Rhea J} and Edwards, {Nick J} and Poulton, {Ian D} and Domtila Kimani and Williams, {Andrew Richard} and Anagnostou, {Nicholas A} and Rachel Roberts and Simon Kerridge and Merryn Voysey and James, {Eric R} and Billingsley, {Peter F} and Anusha Gunasekera and Lawrie, {Alison M} and Hoffman, {Stephen L} and Hill, {Adrian V S}",
year = "2013",
doi = "10.1371/journal.pone.0065960",
language = "English",
volume = "8",
pages = "e65960",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "6",
}
RIS
TY - JOUR
T1 - Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe
AU - Sheehy, Susanne H
AU - Spencer, Alexandra J
AU - Douglas, Alexander D
AU - Sim, B Kim Lee
AU - Longley, Rhea J
AU - Edwards, Nick J
AU - Poulton, Ian D
AU - Kimani, Domtila
AU - Williams, Andrew Richard
AU - Anagnostou, Nicholas A
AU - Roberts, Rachel
AU - Kerridge, Simon
AU - Voysey, Merryn
AU - James, Eric R
AU - Billingsley, Peter F
AU - Gunasekera, Anusha
AU - Lawrie, Alison M
AU - Hoffman, Stephen L
AU - Hill, Adrian V S
PY - 2013
Y1 - 2013
N2 - Controlled human malaria infection (CHMI) studies have become a routine tool to evaluate efficacy of candidate anti-malarial drugs and vaccines. To date, CHMI trials have mostly been conducted using the bite of infected mosquitoes, restricting the number of trial sites that can perform CHMI studies. Aseptic, cryopreserved P. falciparum sporozoites (PfSPZ Challenge) provide a potentially more accurate, reproducible and practical alternative, allowing a known number of sporozoites to be administered simply by injection.
AB - Controlled human malaria infection (CHMI) studies have become a routine tool to evaluate efficacy of candidate anti-malarial drugs and vaccines. To date, CHMI trials have mostly been conducted using the bite of infected mosquitoes, restricting the number of trial sites that can perform CHMI studies. Aseptic, cryopreserved P. falciparum sporozoites (PfSPZ Challenge) provide a potentially more accurate, reproducible and practical alternative, allowing a known number of sporozoites to be administered simply by injection.
U2 - 10.1371/journal.pone.0065960
DO - 10.1371/journal.pone.0065960
M3 - Journal article
C2 - 23823332
VL - 8
SP - e65960
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 6
ER -
