Pathobiological Sciences

  1. 2021
  2. Published

    Detecting bird’s eggs in the diet of raccoon dog (Nyctereutes procyonoides)

    Bahlke, S. Ø., Nash, David Richard, Pedersen, Jes Søe, Hansen, Mette Sif, Chriél, M. & Pagh, S., 2021, In: Genetics and Biodiversity Journal. 5, 2, p. 127-139 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Development of an aerogenous Escherichia coli infection model in adult broiler breeders

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2021, In: Scientific Reports. 11, 15 p., 19556.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Development of the entorhinal cortex occurs via parallel lamination during neurogenesis

    Liu, Y., Bergmann, T., Mori, Yuki, Peralvo Vidal, Juan Miguel, Pihl, M., Vasistha, Navneet A, Thomsen, Preben Dybdahl, Seemann, Ernst Stefan, Gorodkin, Jan, Hyttel, P., Khodosevich, Konstantin, Witter, M. P. & Hall, Vanessa Jane, 2021, In: Frontiers in Neuroanatomy. 15, 19 p., 663667.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, Helle S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Early risk factors, development, disappearance and contents of umbilical outpouching in Danish pigs

    Hovmand-Hansen, T., Jensen, T. B., Vestergaard, K., Nielsen, M. B. F., Leifsson, Páll S. & Jensen, Henrik Elvang, 2021, In: Livestock Science. 251, 9 p., 104654.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effect of age on the vascular proteome in middle cerebral arteries and mesenteric resistance arteries in mice

    Rabaglino, M. B., Wakabayashi, M., Pearson, J. T. & Jensen, Lars Jørn, 2021, In: Mechanisms of Ageing and Development. 200, 111594.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Enhanced Physiological Stress Response in Patients with Normal Tension Glaucoma during Hypoxia

    Dalgaard, L. M., Vibæk, J., Vohra, Rupali, Jensen, Lars Thorbjørn, Cvenkel, B., Secher, Niels H., Olsen, N. V. & Kolko, Miriam, 2021, In: Journal of Ophthalmology. 2021, 5826361.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Epigenomic and transcriptomic analyses reveal early activation of the HPG axis in in vitro-produced male dairy calves

    Rabaglino, M. B., Secher, Jan Bojsen-Møller, Sirard, M. A., Hyttel, P. & Kadarmideen, H. N., 2021, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 35, 10, e21882.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Epigenomics and transcriptomics of muscle and liver tissues from in vitro- and in vivo-produced dairy calves at 3 months of age

    Rabaglino, M., Secher, Jan Bojsen-Møller, Hyttel, P. & Kadarmideen, H., 2021, In: Reproduction, fertility, and development. 34, 2, p. 316 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  11. Published

    Estimation of the age and reproductive performance of wild-born and escaped mink (Neovison vison) caught in the wild in Denmark

    Pagh, S., Pertoldi, C., Chriel, M., Petersen, H. H., Jensen, T. H., Madsen, S., Kraft, D. C. E., Schou, T. M. & Hansen, Mette Sif, 2021, In: Animals. 11, 1, 11 p., 162.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Evaluating a tylosin dosage regimen for treatment of Staphylococcus delphini infection in mink (Neovison vison): a pharmacokinetic-pharmacodynamic approach

    Ronaghinia, A. A., Birch, Julie Knippel Melsted, Frandsen, H. L., Toutain, P. L., Damborg, Peter Panduro & Struve, T., 2021, In: Veterinary Research. 52, 1, 16 p., 34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Evaluation of electrocardiographic repolarization parameters after administration of trimethoprim-sulfadiazine, detomidine, or their combination in horses

    Trachsel, D. S., Callø, Kirstine, Jørgensen, Elin , Lunddahl, C. S., Pedersen, P. J., Kanters, Jørgen K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: American Journal of Veterinary Research. 82, 3, p. 207-217 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Exercise-Associated Sudden Death in Finnish Standardbred and Coldblooded Trotters - A Case Series With Pedigree Analysis

    Trachsel, D. S., Callø, Kirstine, Mykkänen, A. K., Raistakka, P., Anttila, M., Fredholm, Merete, Tala, M., Lamminpää, K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: Journal of Equine Veterinary Science. 104, 103694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Andersen, Jens Velde, Vinten, K. T., Pinborg, Lars Hageman, Waagepetersen, Helle S., Freude, Kristine & Aldana, Blanca, 2021, In: Frontiers in Aging Neuroscience. 13, 736580.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets

    Garcia Bermudez, Mariana Yolotzin, Freude, Kristine, Mouhammad, Zaynab Ahmad, van Wijngaarden, P., Martin, K. K. & Kolko, Miriam, 2021, In: Frontiers in Neurology. 12, 17 p., 624983.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, H., Westi, Emil Winther, Diaz-delCastillo, M., Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, Helle S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Histological examination of testes and epididymides from boars naturally infected with porcine reproductive and respiratory syndrome virus (PRRSV)

    Blirup-Plum, Sophie Amalie, Larsen, Lars, Jensen, Henrik Elvang, Kristensen, C. S. & Kvisgaard, L. K., 2021.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  19. Published

    Histopathology: Histopathological diagnosis using conventional staining techniques, with a key to identification

    Jensen, Henrik Elvang, Vonk, A. G., Verdijk, R., Boer, H. D., Lee, H. V. D. & Rijs, T., 2021, Atlas of clinical fungi: The ultimate benchtool for diagnostics. de Hoog, G. S., Guarro, J., Gené, J., Ahmed, S., Al-Hatmi, A. M. S., Figueras, M. J. & Vitale, R. G. (eds.). 4 ed. 15 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  20. Published

    Histopathology in the Diagnosis of Invasive Fungal Diseases

    Jensen, Henrik Elvang, 2021, In: Current Fungal Infection Reports. 15, 1, p. 23-31 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Hornless cattle – is gene editing the best solution?

    Sandøe, Peter, Borchersen, S., Dean, Wesley, Hyttel, P., Sørensen, L. P. & Palmer, C., 2021, Justice and food security in a changing climate: EurSafe 2021, Fribourg, Switzerland, 24-26 June 2021. Schübel, H. & Wallimann-Helmer, I. (eds.). Wageningen Academic Publishers, p. 324-330 7 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  22. Published

    Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)

    Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, Nana Isabella, Ozgür, Burak, Holst, B., Shusta, E., Hall, Vanessa Jane, Saaby, Lasse, Hyttel, P. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism

    Okarmus, J., Havelund, J. F., Ryding, M., Schmidt, S. I., Bogetofte, H., Heon-Roberts, R., Wade-Martins, R., Cowley, S. A., Ryan, B. J., Færgeman, N. J., Hyttel, P. & Meyer, M., 2021, In: Stem Cell Reports. 16, 6, p. 1510-1526 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Implant-associated osteomyelitis: Development, characterisation, and application of a porcine model

    Jensen, Louise Kruse, 2021, University of Copenhagen. 72 p.

    Research output: Book/ReportDoctoral thesisResearch

  25. Published

    Implant-associated osteomyelitis: Development, characterisation, and application of a porcine model

    Jensen, Louise Kruse, 2021, In: APMIS. 129, S141, p. 1-44 44 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Implications of Glycosylation in Alzheimer’s Disease

    Haukedal, H. & Freude, Kristine, 2021, In: Frontiers in Neuroscience. 14, 18 p., 625348.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Increased fibroblast accumulation in the equine heart following persistent atrial fibrillation

    Saljic, Arnela, Fenner, Merle Friederike, Winters, J., Flethøj, M., Eggert Eggertsen, C., Carstensen, Helena, Nissen, Sarah Dalgas, Melis Hesselkilde, E., van Hunnik, A., Schotten, U., Sørensen, U., Jespersen, Thomas, Verheule, S. & Buhl, Rikke, 2021, In: IJC Heart and Vasculature. 35, 100842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Infection, recovery and re-infection of farmed mink with SARS-CoV-2

    Rasmussen, T. B., Fonager, J., Jørgensen, C. S., Lassaunière, R., Hammer, Anne Sofie Vedsted, Quaade, Michelle Lauge, Boklund, Anette, Lohse, L., Strandbygaard, B., Rasmussen, M., Michaelsen, T. Y., Mortensen, S., Fomsgaard, A., Belsham, Graham John & Bøtner, A., 2021, In: PLOS Pathogens. 17, 11, e1010068.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells

    Schmidt, S. I., Bogetofte, H., Ritter, L., Agergaard, Jette Bach, Hammerich, D., Kabiljagic, A. A., Wlodarczyk, A., Lopez, S. G., Sørensen, M. D., Jørgensen, M. L., Okarmus, J., Serrano, A. M., Kristensen, Bjarne Winther, Freude, Kristine, Owens, T. & Meyer, M., 2021, In: Stem Cell Reports. 16, p. 1-14

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Molecular Techniques for Genus and Species Determination of Fungi From Fresh and Paraffin-Embedded Formalin-Fixed Tissue in the Revised EORTC/MSGERC Definitions of Invasive Fungal Infection

    Lockhart, S. R., Bialek, R., Kibbler, C. C., Cuenca-Estrella, M., Jensen, Henrik Elvang & Kontoyiannis, D. P., 2021, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 72, 2, p. S109-S113

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Molecular characterization of highly pathogenic avian influenza viruses h5n6 detected in denmark in 2018–2019

    Liang, Yuan, Krog, J. S., Ryt-Hansen, Pia, Pedersen, A. G., Kvisgaard, L. K., Holm, E., Nielsen, P. D., Hammer, Anne Sofie Vedsted, Madsen, Jesper Johannes, Thorup, Kasper, Larsen, Lars & Hjulsager, C. K., 2021, In: Viruses. 13, 6, 1052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Neural Derivates of Canine Induced Pluripotent Stem Cells-Like Cells From a Mild Cognitive Impairment Dog

    Chandrasekaran, Abinaya, Thomsen, B. B., Agerholm, Jørgen Steen, Pessôa, L. V. D. F., Godoy Pieri, N. C., Sabaghidarmiyan, V., Langley, K., Kolko, Miriam, De Andrade, A. F. C., Bressan, F. F., Hyttel, P., Berendt, Mette & Freude, Kristine, 2021, In: Frontiers in Veterinary Science. 8, 14 p., 725386.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Neuronal alpha-amylase is important for neuronal activity and glycogenolysis and reduces in presence of amyloid beta pathology

    Byman, E., Martinsson, I., Haukedal, H., Gouras, G., Freude, Kristine, Wennstrom, M. & Netherlands Brain Ban, N. B. B., 2021, In: Aging Cell. 20, 8, 14 p., 13433.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington’s Disease?

    Duque Villegas, Luisana Carolina, Nørremølle, Anne, Freude, Kristine & Vilhardt, Frederik, 2021, In: Frontiers in Aging Neuroscience. 13, 20 p., 736734.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction

    Tribble, J. R., Otmani, A., Sun, S., Ellis, S. A., Cimaglia, G., Vohra, R., Jöe, M., Lardner, E., Venkataraman, A. P., Domínguez-Vicent, A., Kokkali, E., Rho, S., Jóhannesson, G., Burgess, R. W., Fuerst, P. G., Brautaset, R., Kolko, M., Morgan, J. E., Crowston, J. G., Votruba, M. & 1 others, Williams, P. A., 2021, In: Redox Biology. 43, 21 p., 101988.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders

    Frederiksen, Henriette Reventlow S, Doehn, U., Tveden-Nyborg, Pernille & Freude, Kristine, 2021, In: Frontiers in Genome Editing. 2, 623717.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Oxidative stress in optic neuropathies

    Sanz-Morello, B., Ahmadi, H., Vohra, Rupali, Saruhanian, S., Freude, Kristine, Hamann, Steffen & Kolko, Miriam, 2021, In: Antioxidants. 10, 10, 27 p., 1538.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Post-weaning diarrhea in pigs weaned without medicinal zinc: risk factors, pathogen dynamics, and association to growth rate

    Eriksen, E. Ø., Kudirkiene, E., Christensen, A. E., Schmidt, Marianne Viuf Agerlin, Weber, N. R., Nødtvedt, A., Nielsen, Jens Peter, Hartmann, Katrine Top, Skade, L., Larsen, Lars, Pankoke, K., Olsen, John Elmerdahl, Jensen, Henrik Elvang & Pedersen, Ken Steen, 2021, In: Porcine Health Management. 7, 54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Preclinical testing of radiopharmaceuticals for the detection and characterization of osteomyelitis: Experiences from a porcine model

    Alstrup, A. K. O., Jensen, S. B., Nielsen, O. L., Jødal, L. & Afzelius, P., 2021, In: Molecules. 26, 14, 4221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Preliminary report of an outbreak of SARS-CoV-2 in mink and mink farmers associated with community spread, Denmark, June to November 2020

    Larsen, H. D., Fonager, J., Lomholt, F. K., Dalby, T., Benedetti, G., Kristensen, B., Urth, T. R., Rasmussen, M., Lassaunière, R., Rasmussen, T. B., Strandbygaard, B., Lohse, L., Chaine, M., Møller, K. L., Berthelsen, A. S. N., Nørgaard, S. K., Sönksen, U. W., Boklund, A. E., Hammer, A. S., Belsham, G. J. & 5 others, Krause, Tyra Grove, Mortensen, S., Bøtner, A., Fomsgaard, A. & Mølbak, Kåre, 2021, In: Eurosurveillance. 26, 5, 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published
  42. Published

    Quantitative proteome comparison of human hearts with those of model organisms

    Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    RT-qPCR assay for detection of mink astrovirus in outbreaks of diarrhea on Danish mink farms

    Barsøe, S., Ullman, K., Leijon, M., Hedlund, K. O., Klingström, J., Krarup, L. I., Andresen, Lars, Quaade, Michelle Lauge & Hammer, Anne Sofie Vedsted, 2021, In: PLoS ONE. 16, 5, e0252022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    SARS-CoV-2 in Danish Mink Farms: Course of the Epidemic and a Descriptive Analysis of the Outbreaks in 2020

    Boklund, Anette, Hammer, Anne Sofie Vedsted, Quaade, Michelle Lauge, Rasmussen, T. B., Lohse, L., Strandbygaard, B., Jørgensen, C. S., Olesen, A. S., Hjerpe, F. B., Petersen, H. H., Jensen, Tim Kåre, Mortensen, S., Calvo-Artavia, F. F., Lefèvre, S. K., Nielsen, Søren Saxmose, Halasa, T., Belsham, Graham John & Bøtner, A., 2021, In: Animals. 11, 1, p. 1-16 16 p., 164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    SARS-CoV-2 transmission between mink (neovison vison) and Humans, Denmark

    Hammer, Anne Sofie Vedsted, Quaade, Michelle Lauge, Rasmussen, T. B., Fonager, J., Rasmussen, M., Mundbjerg, K., Lohse, L., Strandbygaard, B., Jørgensen, C. S., Alfaro-Núñez, A., Rosenstierne, M. W., Boklund, Anette, Halasa, T., Fomsgaard, A., Belsham, Graham John & Bøtner, A., 2021, In: Emerging Infectious Diseases . 27, 2, p. 547-551 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The Development of Contractures in Cerebral Palsy and Stroke: Pathophysiological Approaches

    Pingel, Jessica, Harrison, Adrian Paul, Korbo, L. & Bartels, E., 2021, In: Journal of Clinical and Experimental Neuroimmunology. 6, 4, 5 p., 1000127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The Effect of Aromatherapy on Equine Facial Expression, Heart Rate, Respiratory Tidal Volume and Spontaneous Muscle Contractures in M. Temporalis and M. Cleidomastoideus

    Kosiara, S. & Harrison, Adrian Paul, 2021, In: Open Journal of Veterinary Medicine. 11, 02, p. 87-103

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The effect of antimicrobial treatment on mortality associated with urinary tract disease in mink kits (Neovison vison)

    Mundbjerg, K., Pedersen, P. E. & Hammer, Anne Sofie Vedsted, 2021, In: Acta Veterinaria Scandinavica. 63, 1, 6 p., 15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The impact of water depth and speed on muscle fiber activation of healthy dogs walking in a water treadmill

    Vitger, Anne Désiré, Bruhn-Rasmussen, T., Pedersen, E. O., Fuglsang-Damgaard, L. H. & Harrison, Adrian Paul, 2021, In: Acta Veterinaria Scandinavica. 63, 1, 46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The narrow-spectrum anthelmintic oxantel is a potent agonist of a novel acetylcholine receptor subtype in whipworms

    Hansen, Tina Vicky Alstrup, Cirera, Susanna, Neveu, C., Courtot, E., Charvet, C. L., Callø, Kirstine, Klærke, Dan Arne & Martin, R. J., 2021, In: P L o S Pathogens. 17, 2, 26 p., e1008982.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Vascular calcium signaling and aging

    Harraz, O. F. & Jensen, Lars Jørn, 2021, In: The Journal of Physiology. 599, 24, p. 5361-5377

    Research output: Contribution to journalJournal articleResearchpeer-review