Pathobiological Sciences

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  1. Published

    The Breakthroughs and Caveats of Using Human Pluripotent Stem Cells in Modelling Alzheimer’s Disease

    Bendtsen, K. M. S. & Hall, Vanessa Jane, 2023, In: Cells. 12, 3, 420.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming

    Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, Hall, Vanessa Jane, 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The developing Entorhinal Cortex – a cellular map

    Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.

    Research output: Contribution to conference › Conference abstract for conference › Research

  4. Published

    The developing Entorhinal cortex - a cellular map

    Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 25 Nov 2019. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  5. Published

    Uncovering the anatomical and molecular landscape of the starting point of Alzheimer’s disease in the brain

    Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.

    Research output: Contribution to conference › Conference abstract for conference › Research

  6. Published

    The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.

    Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research

  7. Published

    Effects of buprenorphine on acute pain and inflammation in the adjuvant-induced monoarthritis rat model

    Berke, M. S., Colding-Jørgensen, Pernille, Hestehave, Sara, Kalliokoski, Otto, Jensen, Henrik Elvang, Sørensen, Dorte Bratbo, Hau, Jann & Abelson, Klas, 2022, In: Heliyon. 8, 11, 9 p., e11554.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Effects of Transdermal Fentanyl Treatment on Acute Pain and Inflammation in Rats with Adjuvant-induced Monoarthritis

    Berke, M. S., Colding-Jørgensen, Pernille, Pedersen, L. G., Hestehave, Sara, Kalliokoski, Otto, Jensen, Henrik Elvang, Sørensen, Dorte Bratbo, Hau, Jann & Abelson, Klas, 2022, In: Comparative Medicine. 72, 5, p. 320–329 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Mammalian embryo comparison identifies novel pluripotency genes associated with the naive or primed state

    Bernardo, A. S., Jouneau, A., Marks, H., Kensche, P., Kobolak, J., Freude, K., Hall, V., Feher, A., Polgar, Z., Sartori, C., Bock, I., Louet, C., Faial, T., Kerstens, H. H. D., Bouissou, C., Parsonage, G., Mashayekhi, K., Smith, J. C., Lazzari, G., Hyttel, P. & 4 others, Stunnenberg, H. G., Huynen, M., Pedersen, R. A. & Dinnyes, A., 2018, In: Biology Open. 7, 8, 17 p., bio033282.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Clinical trial of the effect of three alternative treatments compared with a standard amoxillin treatment in mink kits with pre-weaning diarrhea

    Birch, Julie Knippel Melsted, Agger, Jens Frederik Gramstrup, Leijon, M., Ullman, K., Struve, T. & Jensen, Henrik Elvang, 2019.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  11. Published

    Transfer of amoxillin to suckling mink (neovison vison) kits via the milk from dams treated orally or intra-muscularly

    Birch, Julie Knippel Melsted, Frandsen, H. L., Struve, T., Agger, Jens Frederik Gramstrup & Jensen, Henrik Elvang, 2019.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  12. Published

    Sequencing of viruses and bacteria from suckling mink kits with diarrhea (PWD)

    Birch, Julie Knippel Melsted, Ullman, K., Struve, T., Agger, Jens Frederik Gramstrup, Hammer, Anne Sofie Vedsted, Leijon, M. & Jensen, Henrik Elvang, 17 Jan 2018.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  13. Published

    Clinical trial of the effect of three alternative treatments compared with a standard amoxillin treatment in mink kits with pre-weaning diarrhea

    Birch, Julie Knippel Melsted, Agger, Jens Frederik Gramstrup, Leijon, M., Ullman, K., Struve, T. & Jensen, Henrik Elvang, 9 Apr 2018.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  14. Published

    Visualization of intestinal infections with astro- and sapovirus in mink (nevison vison) kits by in situ hybridization

    Birch, Julie Knippel Melsted, Leijon, M., Nielsen, Søren Saxmose, Struve, T. & Jensen, Henrik Elvang, 2021, In: FEMS Microbes. 2, 6 p., xtab005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Comparing the treatment effect of narrow spectrum antimicrobial, probiotic and fluid with amoxicillin in mink kits (Neovison vison) with pre-weaning diarrhea

    Birch, Julie Knippel Melsted, Agger, Jens Frederik Gramstrup, Leijon, M., Ullman, K., Struve, T. & Jensen, Henrik Elvang, 2019, In: Research in Veterinary Science. 125, p. 121-129 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Comparing video examinations with physical clinical examinations using finishing pigs with umbilical outpouchings as a model

    Birch, Julie Knippel Melsted & Pedersen, Ken Steen, 2023, In: Acta Veterinaria Scandinavica. 65, 26.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Visualization of intestinal infections with astro- and sapovirus in mink (Neovison vison) kits by in situ hybridization

    Birch, Julie Knippel Melsted, Leijon, M., Nielsen, Søren Saxmose, Struve, T. & Jensen, Henrik Elvang, 2021, In: FEMS Microbes. 2, 6 p., xtab005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Transfer of amoxicillin to suckling mink (Neovison vison) kits via the milk from dams treated orally or intra-muscularly

    Birch, Julie Knippel Melsted, Frandsen, H. L., Struve, T., Agger, Jens Frederik Gramstrup & Jensen, Henrik Elvang, 2019, In: Research in Veterinary Science. 123, p. 47-50 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Syncytin-1 and its receptor is present in human gametes

    Bjerregaard, B., Lemmen, J. G., Petersen, M. R., Østrup, E., Iversen, L. H., Almstrup, Kristian, Larsson, L. I. & Ziebe, S., May 2014, In: Journal of Assisted Reproduction and Genetics. 31, 5, p. 533-539 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Role of age, Rho-kinase 2 expression, and G protein-mediated signaling in the myogenic response in mouse small mesenteric arteries

    Björling, K., Joseph, P. D., Egebjerg, K., Salomonsson, M., Hansen, J. L., Ludvigsen, T. P. & Jensen, Lars Jørn, 10 Sep 2018, In: Physiological Reports. 6, 17, 17 p., e13863.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    G protein-mediated signaling in the myogenic response – role of Rho-kinase and aging

    Björling, K., Joseph, P. D., Egebjerg, K., Hansen, J. L., Salomonsson, M. & Jensen, Lars Jørn, 2017, In: Journal of Vascular Research. 54, S2, p. 9 1 p., 8.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. Published

    Pathological and microbiological impact of a gentamicin-loaded biocomposite following limited or extensive debridement in a porcine model of osteomyelitis

    Blirup-Plum, Sophie Amalie, Bjarnsholt, Thomas, Jensen, Henrik Elvang, Kragh, K. N., Aalbæk, Bent, Gottlieb, Hans, Bue, M. & Jensen, Louise Kruse, 2020, In: Bone and Joint Research. 9, 7, p. 394-401 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Gastro-intestinal lesions are not relatable to diarrhoea or specific pathogens in post-weaning diarrhoea (PWD) in pigs

    Blirup-Plum, Sophie Amalie, Jensen, Henrik Elvang, Nielsen, Søren Saxmose, Pankoke, K., Hansen, Mette Sif, Pedersen, Ken Steen, Eriksen, E. Ø., Nielsen, Jens Peter, Olsen, John Elmerdahl, Kudirkiene, E., Larsen, Lars, Goecke, Nicole Bakkegård & Barington, Kristiane, 2023, In: Acta Veterinaria Scandinavica. 65, p. 1-18 18 p., 30.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Histological examination of testes and epididymides from boars naturally infected with porcine reproductive and respiratory syndrome virus (PRRSV)

    Blirup-Plum, Sophie Amalie, Larsen, Lars, Jensen, Henrik Elvang, Kristensen, C. S. & Kvisgaard, L. K., 2021.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  25. Published

    Histopathology of intestinal lesions in a case-control study of post-weaning diarrhoea (PWD) in pigs

    Blirup-Plum, Sophie Amalie, 16 Jun 2022.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  26. Published

    SARS-CoV-2 in Danish Mink Farms: Course of the Epidemic and a Descriptive Analysis of the Outbreaks in 2020

    Boklund, Anette, Hammer, Anne Sofie Vedsted, Quaade, Michelle Lauge, Rasmussen, T. B., Lohse, L., Strandbygaard, B., Jørgensen, C. S., Olesen, A. S., Hjerpe, F. B., Petersen, H. H., Jensen, Tim Kåre, Mortensen, S., Calvo-Artavia, F. F., Lefèvre, S. K., Nielsen, Søren Saxmose, Halasa, T., Belsham, Graham John & Bøtner, A., 2021, In: Animals. 11, 1, p. 1-16 16 p., 164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Author Correction: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 (Nature Biotechnology, (2019), 37, 8, (852-857), 10.1038/s41587-019-0209-9)

    Bolyen, E., Rideout, J. R., Dillon, M. R., Bokulich, N. A., Abnet, C. C., Al-Ghalith, G. A., Alexander, H., Alm, E. J., Arumugam, M., Asnicar, F., Bai, Y., Bisanz, J. E., Bittinger, K., Brejnrod, A., Brislawn, C. J., Brown, C. T., Callahan, B. J., Caraballo-Rodríguez, A. M., Chase, J., Cope, E. K. & 92 others, Da Silva, R., Diener, C., Dorrestein, P. C., Douglas, G. M., Durall, D. M., Duvallet, C., Edwardson, C. F., Ernst, M., Estaki, M., Fouquier, J., Gauglitz, J. M., Gibbons, S. M., Gibson, D. L., Gonzalez, A., Gorlick, K., Guo, J., Hillmann, B., Holmes, S., Holste, H., Huttenhower, C., Huttley, G. A., Janssen, S., Jarmusch, A. K., Jiang, L., Kaehler, B. D., Kang, K. B., Keefe, C. R., Keim, P., Kelley, S. T., Knights, D., Koester, I., Kosciolek, T., Kreps, J., Langille, M. G. I., Lee, J., Ley, R., Liu, Y. X., Loftfield, E., Lozupone, C., Maher, M., Marotz, C., Martin, B. D., McDonald, D., McIver, L. J., Melnik, A. V., Metcalf, J. L., Morgan, S. C., Morton, J. T., Naimey, A. T., Navas-Molina, J. A., Nothias, L. F., Orchanian, S. B., Pearson, T., Peoples, S. L., Petras, D., Preuss, M. L., Pruesse, E., Rasmussen, L. B., Rivers, A., Robeson, M. S., Rosenthal, P., Segata, N., Shaffer, M., Shiffer, A., Sinha, R., Song, S. J., Spear, J. R., Swafford, A. D., Thompson, L. R., Torres, P. J., Trinh, P., Tripathi, A., Turnbaugh, P. J., Ul-Hasan, S., van der Hooft, J. J. J., Vargas, F., Vázquez-Baeza, Y., Vogtmann, E., von Hippel, M., Walters, W., Wan, Y., Wang, M., Warren, J., Weber, K. C., Williamson, C. H. D., Willis, A. D., Xu, Z. Z., Zaneveld, J. R., Zhang, Y., Zhu, Q., Knight, R. & Caporaso, J. G., 1 Sep 2019, In: Nature Biotechnology. 37, 9, p. 1091 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  28. Published

    Chromatin organization, spatial localization of heterochromatin sequences and nucleolar activity, change towards final maturation in porcine oocytes

    Bonnet-Garnier, A., Benc, M., Bartkova, A., Pihl, M., Chebrout, M., Strejcek, F., Hyttel, P., Lucas-Hahn, A., Laurincik, J., Freude, Kristine & Fenner, Merle Friederike, 2023. 1 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  29. Published

    Early pathogenesis in porcine proliferative enteropathy caused by Lawsonia intracellularis

    Boutrup, T. S., Boesen, H. T., Boye, M., Agerholm, Jørgen Steen & Jensen, Tim Kåre, 2010, In: Journal of Comparative Pathology. 143, 2-3, p. 101-109 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    A viral metagenomic approach on a nonmetagenomic experiment: Mining next generation sequencing datasets from pig DNA identified several porcine parvoviruses for a retrospective evaluation of viral infections

    Bovo, S., Mazzoni, G., Ribani, A., Utzeri, V. J., Bertolini, F., Schiavo, G. & Fontanesi, L., 2017, In: PLOS ONE. 12, 6, 17 p., e0179462.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Effect of increasing dietary methionine-to-lysine ratio during early gestation on fetal development and piglet birth weight

    Bruun, T. S., Østrup, E., Lyderik, Kimmie Kyed, Dall, J. & Strathe, Anja Varmløse, 2023, In: Animal Reproduction Science. 252, 107251.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Inflammatory proteins in infected bone tissue – An explorative porcine study

    Bue, M., Bergholt, N. L., Jensen, Louise Kruse, Jensen, Henrik Elvang, Søballe, K., Stilling, M. & Hanberg, P., 2020, In: Bone Reports. 13, 7 p., 100292.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Neuronal alpha-amylase is important for neuronal activity and glycogenolysis and reduces in presence of amyloid beta pathology

    Byman, E., Martinsson, I., Haukedal, H., Gouras, G., Freude, Kristine, Wennstrom, M. & Netherlands Brain Ban, N. B. B., 2021, In: Aging Cell. 20, 8, 14 p., 13433.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Vectorborne zoonoses

    Bødker, René, Reipurth, M., Hammer, Anne Sofie Vedsted, Lohse, L. & Kjær, Lene Jung, 2022, Annual Report on Zoonoses in Denmark 2021. Olsen, A., Høg, B. B., Sandberg, M., Müller, L. & Torpdahl, M. (eds.). Technical University of Denmark, p. 17-20 (Annual Report on Zoonoses in Denmark, Vol. 2021).

    Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

  35. Published

    A simple and scalable 3D printing methodology for generating aligned and extended human and murine skeletal muscle tissues

    Cakal, S. D., Radeke, C., Alcala, J. F., Ellman, D. G., Butdayev, S., Andersen, D. C., Callø, Kirstine & Lind, J. U., 2022, In: Biomedical Materials (Bristol). 17, 4

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Nav1.5 gain-of-function mutation (G213D)

    Callø, Kirstine, Broendberg, A. K., Christensen, A. H., Pedersen, L. N., Olesen, Morten Steen Salling, de Los Angeles Tejada, M., Friis, S., Thomsen, Morten Bækgaard, Bundgård, Henning & Jensen, H. K., 15 Apr 2018, In: International Journal of Cardiology. 257, p. 160-167 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Interventricular differences in sodium current and its potential role in Brugada syndrome

    Callø, Kirstine, Aistrup, G. L., Di Diego, J. M., Goodrow, R. J., Treat, J. A. & Cordeiro, J. M., 2018, In: Physiological Reports. 6, 14, 12 p., e13787.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Multifocal ectopic purkinje-related premature contractions and related cardiomyopathy

    Callø, Kirstine, Magnusson, H. B. D., Lildballe, D. L., Christiansen, M. K. & Jensen, H. K., 2023, In: Frontiers in Cardiovascular Medicine. 10, 1179018.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel K v 11.1

    Callø, Kirstine, Rognant, Salomé, Friis, S., Shaughnessy, C., Klærke, Dan Arne & Trachsel, D., 2019, In: Research in Veterinary Science. 123, p. 239-246 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The loss-of-function variant p.M764R in the cardiac sodium channel Nav1.5 is associated with ventricular arrhythmias and sudden cardiac death in a family without overt Brugada syndrome

    Callø, Kirstine, Christiansen, M. K., Henriksen, F. L. & Jensen, H. K., Feb 2024, In: HeartRhythm Case Reports. 10, 2, p. 137-141 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    A dual potassium channel activator improves repolarization reserve and normalizes ventricular action potentials

    Callø, Kirstine, Di Diego, J. M., Hansen, R. S., Nagle, S. A., Treat, J. A. & Cordeiro, J. M., 19 Mar 2016, In: Biochemical Pharmacology. 108, p. 36-46 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Doctoral Dissertation: The transient outward potassium current in healthy and diseased hearts

    Callø, Kirstine, Jan 2019, In: Acta Physiologica. 225 , S717, e13225.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Acquired LQTS in horses

    Callø, Kirstine, Trachsel, D. S., Rognant, Salomé, Friis, S., Pedersen, P. J. & Klærke, Dan Arne, 8 Aug 2019.

    Research output: Contribution to conference › Poster › Communication

  45. Published

    The Transient Outward Potassium Current in Healthy and Diseased Hearts

    Callø, Kirstine, 2019, Københavns Universitet.

    Research output: Book/Report › Doctoral thesis › Research

  46. Published

    Assessment of Noninvasive Low-Frequency Ultrasound as a Means of Treating Injuries to Suspensory Ligaments in Horses: A Research Paper

    Carrozzo, U., Toniato, M. & Harrison, Adrian Paul, 2019, In: Journal of Equine Veterinary Science. 80, p. 80-89 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Probing motor dynamics at the muscle level — Acoustic myography in Parkinson's disease

    Celicanin, M., Harrison, Adrian Paul, Olsen, J. K., Korbo, L., Løkkegaard, Annemette, Danneskiold-Samsøe, B., Siebner, Hartwig Roman, Ilic, T. V. & Bartels, E. M., 2023, In: Physiological Reports. 11, 6, 13 p., e15631.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Probing cellular health at the muscle level—Multi-frequency bioimpedance in Parkinson's disease

    Celicanin, M., Harrison, Adrian Paul, Olsen, J. K., Korbo, L., Løkkegaard, Annemette, Petersen, C. B., Danneskiold-Samsøe, B., Siebner, Hartwig Roman, Ilic, T. & Bartels, E. M., 2022, In: Physiological Reports. 10, 19, e15465.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    A protein-centric view of in vitro biological model systems for schizophrenia

    Chandrasekaran, Abinaya, Jensen, P., Mohamed, Fadumo Abdullahi, Lancaster, M., Benros, Michael Eriksen, Larsen, M. R. & Freude, Kristine, 2021, In: Stem Cells. 39, 12, p. 1569-1578

    Research output: Contribution to journal › Review › Research › peer-review

  50. Published

    Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

    Chandrasekaran, Abinaya, Avci, H., Ochalek, A., Rosingh, L., Molnar, K., Laszlo, L., Bellak, T., Teglasi, A., Pesti, K., Mike, A., Phanthong, P., Biro, O., Hall, Vanessa Jane, Kitiyanant, N., Krause, K., Kobolak, J. & Dinnyés, A., 2017, In: Stem Cell Research. 25, p. 139-151

    Research output: Contribution to journal › Journal article › Research › peer-review

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