Pathobiological Sciences

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  1. 2019
  2. Published

    Assessment of Noninvasive Low-Frequency Ultrasound as a Means of Treating Injuries to Suspensory Ligaments in Horses: A Research Paper

    Carrozzo, U., Toniato, M. & Harrison, Adrian Paul, 2019, In: Journal of Equine Veterinary Science. 80, p. 80-89 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Cell type specific expression of toll-like receptors in human brains and implications in Alzheimer's disease

    Frederiksen, Henriette Reventlow S, Haukedal, H. & Freude, Kristine, 2019, In: BioMed Research International. 2019, 18 p., 7420189.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene

    Chumarina, M., Russ, K., Azevedo, C., Heuer, A., Pihl, M., Collin, A., Frostner, E. Å., Elmer, E., Hyttel, P., Cappelletti, G., Zini, M., Goldwurm, S. & Roybon, L., 2019, In: Acta Neuropathologica Communications. 7, 1, 19 p., 208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Characterization of eQTLs associated with androstenone by RNA sequencing in porcine testis

    Drag, Markus Hodal, Kogelman, L. J. A., Maribo, H., Meinert, L., Thomsen, Preben Dybdahl & Kadarmideen, H. N., 2019, In: Physiological Genomics. 51, 10, p. 488-499 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Clinical trial of the effect of three alternative treatments compared with a standard amoxillin treatment in mink kits with pre-weaning diarrhea

    Birch, Julie Knippel Melsted, Agger, Jens Frederik Gramstrup, Leijon, M., Ullman, K., Struve, T. & Jensen, Henrik Elvang, 2019.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  7. Published

    Cold case reopened: finding clues to recurrent mass mortalities in Greenland sled dogs (Canis lupus familiaris borealis)

    Andersen-Ranberg, E. U., Vernersen, Emilie Sandager, Jensen, J. J., Houser, G., Sonne, C. & Langebæk, Rikke, 2019, In: Polar Biology. 42, 7, p. 1411-1413 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  8. Published

    Comparative Osteology: A Cross-Species Study of First Rib Parameters and Their Relation to Body Mass with Emphasis on the Woolly Mammoth

    Harrison, Adrian Paul, Pringel, J. & Bülow, J., 2019, In: American Journal of Biomedical Science & Research. 3, 4, p. 340-346

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Comparing the treatment effect of narrow spectrum antimicrobial, probiotic and fluid with amoxicillin in mink kits (Neovison vison) with pre-weaning diarrhea

    Birch, Julie Knippel Melsted, Agger, Jens Frederik Gramstrup, Leijon, M., Ullman, K., Struve, T. & Jensen, Henrik Elvang, 2019, In: Research in Veterinary Science. 125, p. 121-129 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Comparison of cultured human cardiomyocyte clusters obtained from embryos/fetuses or derived from human embryonic stem cells

    Grubb, Søren, Vestergaard, M. L., Andersen, A. S., Rasmussen, K. K., Mamsen, L., Tuckute, G., Grunnet-Lauridsen, K., Møllgård, Kjeld, Ernst, E., Christensen, Søren Tvorup, Callø, Kirstine & tcg964, tcg964, 2019, In: Stem Cells and Development. 28, 9, p. 608-619

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Compounds commonly used in equine medicine inhibits the voltage-gated potassium channel K v 11.1

    Callø, Kirstine, Rognant, Salomé, Friis, S., Shaughnessy, C., Klærke, Dan Arne & Trachsel, D., 2019, In: Research in Veterinary Science. 123, p. 239-246 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Dementia, Brain Disorders and Molecular Mechanisms

    Freude, Kristine & Krauss, S., 2019, In: Journal of Molecular Biology. 431, 9, p. 1709-1710

    Research output: Contribution to journal › Editorial › Research

  13. Published

    Denmark's exemplary gender balance trips up in science

    Bendixen, M., Meehan, Claire Francesca, Hall, Vanessa Jane & Vogel, I., 2019, In: Nature. 572, 7768, p. 178 1 p.

    Research output: Contribution to journal › Comment/debate › Communication

  14. Published

    Does Rider Weight have a Measurable Effect on the Horse’s Back Muscle Longissimus dorsi?

    Andersen, N. E. & Harrison, Adrian Paul, 2019, In: Integrative Journal of Veterinary Biosciences. 3, 1, 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Editorial: Socially-responsible media: #totweetornottotweet?

    Knight, C. H., 2019, In: Journal of Dairy Research. 86, 4, p. 377-378 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  16. Published

    Editorial: Next generation dairying

    Knight, C. H., 2019, In: Journal of Dairy Research. 86, 1, p. 1-2 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  17. Published

    Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)

    Jespersen, Thomas, Fenner, Merle Friederike & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 96-96

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  18. Published

    Effect of TRPA1 activator allyl isothiocyanate (AITC) on rat dural and pial arteries

    Hansted, A. K., Bhatt, D. K., Olesen, Jes, Jensen, Lars Jørn & Jansen-Olesen, I., 2019, In: Pharmacological Reports. 71, 4, p. 565-572 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Equine myodural bridges - An Anatomical and integrative/functional description of myodural bridges along the spine of horses: Special focus on the atlanto-occipital and atlanto-axial regions.

    Elbrønd (Bibs), Vibeke Sødring & Mark Schultz, R., 2019, In: Medical Research Archives. 7, 11, p. 1-20 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Evidence for nucleolar dysfunction in Alzheimer's disease

    Nyhus, C., Pihl, M., Hyttel, P. & Hall, Vanessa Jane, 2019, In: Reviews in the Neurosciences. 30, 7, p. 685–700

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    Forensic Evaluation of Bruises in Pigs

    Barington, Kristiane, 2019, Copenhagen.

    Research output: Book/Report › Doctoral thesis › Research

  22. Published

    Generation and miRNA Characterization of Equine Induced Pluripotent Stem Cells Derived from Fetal and Adult Multipotent Tissues

    Pessoa, L. V. D. F., Pires, P. R. L., Collado, M. D., Pieri, N. C. G., Recchia, K., Souza, A. F., Perecin, F., Da Silveira, J. C., Andrade, A. F. C. D., Ambrosio, C. E., Bressan, F. F. & Meirelles, F. V., 2019, In: Stem Cells International. 2019, 1393791.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Genetic protection modifications: Moving beyond the binary distinction between therapy and enhancement for human genome editing

    Mikkelsen, R. C. B., Frederiksen, Henriette Reventlow S, Gjerris, Mickey, Holst, B., Hyttel, P., Luo, Y., Freude, Kristine & Sandøe, Peter, 2019, In: CRISPR Journal. 2, 6, p. 362-369 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genital Infiltrations of CD4(+) and CD8(+) T Lymphocytes, IgA(+) and IgG(+) Plasma Cells and Intra-Mucosal Lymphoid Follicles Associate With Protection Against Genital Chlamydia trachomatis Infection in Minipigs Intramuscularly Immunized With UV-Inactivated Bacteria Adjuvanted With CAF01

    Erneholm, K., Lorenzen, E., Boje, S., Olsen, A. W., Jungersen, G., Jensen, Henrik Elvang, Cassidy, J. P., Andersen, P., Agerholm, Jørgen Steen & Follmann, F., 2019, In: Frontiers in Microbiology. 10, 10 p., 197.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium

    Cornely, O. A., Alastruey-Izquierdo, A., Arenz, D., Chen, S. C. A., Dannaoui, E., Hochhegger, B., Hoenigl, M., Jensen, H. E., Lagrou, K., Lewis, R. E., Mellinghoff, S. C., Mer, M., Pana, Z. D., Seidel, D., Sheppard, D. C., Wahba, R., Akova, M., Alanio, A., Al-Hatmi, A. M. S., Arikan-Akdagli, S. & 31 others, Badali, H., Ben-Ami, R., Bonifaz, A., Bretagne, S., Castagnola, E., Chayakulkeeree, M., Colombo, A. L., Corzo-León, D. E., Drgona, L., Groll, A. H., Guinea, J., Heussel, C., Ibrahim, A. S., Kanj, S. S., Klimko, N., Lackner, M., Lamoth, F., Lanternier, F., Lass-Floerl, C., Lee, D., Lehrnbecher, T., Lmimouni, B. E., Mares, M., Maschmeyer, G., Meis, J. F., Meletiadis, J., Morrissey, C. O., Nucci, M., Oladele, R., Pagano, L. & Mucormycosis ECMM MSG Global Guideline Writing Group, M. E. M. G. G. W. G., 2019, In: Lancet Infectious Diseases. 19, 12, p. e405-e421

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Guideline for Preclinical Studies of Bone Infections in Large Animals Based on a Systematic Review of 316 Non-Rodent Models

    Jensen, Louise Kruse, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie & Jensen, Henrik Elvang, 2019, In: The Journal of bone and joint surgery. American volume. 101, 21, p. 1894-1903 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Guidelines for porcine models of human bacterial infections

    Jensen, Louise Kruse, Henriksen, Nicole Lind & Jensen, Henrik Elvang, 2019, In: Laboratory Animals. 53, 2, p. 125-136

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Histology of Sculpin spp. in East Greenland. II. Histopathology and trace element concentrations

    Kaarsholm, H. M., Verland, N., Nørregaard, R. D., Bach, L., Søndergaard, J., Rigét, F. F., Dietz, R., Hansen, M., Eulaers, I., Desforges, J. P., Leifsson, Páll S., Dang, M., Nowak, B. & Sonne, C., 2019, In: Toxicological and Environmental Chemistry. 100, 8-10, p. 769–784

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Hyperglycemia-induced transcriptional regulation of ROCK1 and TGM2 expression is involved in small artery remodeling in obese diabetic Göttingen Minipigs

    Ludvigsen, T. P., Olsen, Lisbeth Høier, Pedersen, H. D., Østergaard Christoffersen, B. & Jensen, Lars Jørn, 2019, In: Clinical Science. 133, 24, p. 2499–2516 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Implantable loop recorders for arrhythmia detection - a new promising diagnostic tool for longterm arrhythmia monitoring

    Hesselkilde, E. Z., Carsten, H., Fenner, Merle Friederike, Jespersen, Thomas, T-felt, J., Sattler, Stefan M & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 93-93 35.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  31. Published

    Implications of Microglia in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

    Haukedal, H. & Freude, Kristine, 2019, In: Journal of Molecular Biology. 431, 9, p. 1818-1829

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    In vivo gentamicin susceptibility test for prevention of bacterial biofilms in bone tissue and on implants

    Jensen, Louise Kruse, Bjarnsholt, Thomas, Kragh, K. N., Aalbæk, Bent, Henriksen, Nicole Lind, Blirup-Plum, Sophie Amalie, Pankoke, K., Petersen, A. & Jensen, Henrik Elvang, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 2, 10 p., e01889-18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Induced pluripotent stem cells throughout the animal kingdom: Availability and applications

    Pessôa, L. V. D. F., Bressan, F. F. & Freude, Kristine, 2019, In: World Journal of Stem Cells. 11, 8, p. 491-505 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Isavuconazole in a Successful Combination Treatment of Disseminated Mucormycosis in a Child with Acute Lymphoblastic Leukaemia and Generalized Haemochromatosis: A Case Report and Review of the Literature

    Pomorska, A., Malecka, A., Jaworski, R., Radon-Proskura, J., Hare, R. K., Nielsen, H. V., Andersen, L. O., Jensen, Henrik Elvang, Arendrup, Maiken Cavling & Irga-Jaworska, N., 2019, In: Mycopathologia. 184, 1, p. 81–88

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    Isolation and culture of porcine primary fetal progenitors and neurons from the developing dorsal telencephalon

    Aubid, N. N., Liu, Y., Peralvo Vidal, Juan Miguel & Hall, Vanessa Jane, 2019, In: Journal of Veterinary Science. 20, 2, 13 p., e3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Kinetic modelling of [68Ga]Ga-DOTA-siglec-9 in porcine osteomyelitis and soft tissue infections

    Jødal, L., Roivainen, A., Oikonen, V., Jalkanen, S., Hansen, S. B., Afzelius, P., Alstrup, A. K. O., Nielsen, O. L. & Jensen, S. B., 2019, In: Molecules. 24, 22, 21 p., 4094.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Metabolic impairments in neurons and astrocytes derived from human induced pluripotent stem cells of Alzheimer's disease patients

    Garcia, B. A., Salcedo, C., Hyttel, P., Waagepetersen, Helle S. & Freude, Kristine, 2019, p. 111-111.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  38. Published

    Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells

    Kobolák, J., Molnár, K., Varga, E., Bock, I., Jezsó, B., Téglási, A., Zhou, S., Lo Giudice, M., Hoogeveen-Westerveld, M., Pijnappel, W. P., Phanthong, P., Varga, N., Kitiyanant, N., Freude, Kristine, Nakanishi, H., László, L., Hyttel, P. & Dinnyés, A., 2019, In: Experimental Cell Research. 380, 2, p. 216-233 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Muscle assessment using multi-frequency bioimpedance in a healthy Danish population aged 20–69 years: a powerful non-invasive tool in sports and in the clinic

    Bartels, E. M., Andersen, E. L., Olsen, J. K., Kristensen, Lars Erik Vølund, Bliddal, Henning, Danneskiold-Samsøe, B. & Harrison, Adrian Paul, 2019, In: Physiological Reports. 7, 11, 9 p., e14109.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Oocytes, embryos and pluripotent stem cells from a biomedical perspective

    Hyttel, P., Pessôa, L. V. D. F., Secher, Jan Bojsen-Møller, Dittlau, Katarina Stoklund, Freude, Kristine, Hall, Vanessa Jane, Fair, T., Assey, R. J., Laurincik, J., Callesen, H., Greve, T. & Stroebech, L. B., 2019, In: Animal Reproduction. 16, 3, p. 508-523 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    PACAP-38 and PACAP(6-38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB3-Receptor

    Pedersen, S. H., la Cour, S. H., Callø, Kirstine, Hauser, Frank, Olesen, Jes, Klærke, Dan Arne & Jansen-Olesen, I., 2019, In: Frontiers in Cellular Neuroscience. 13, 11 p., 114.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Production of stellate cells from induced pluripotent stem cells to study Alzheimer's disease pathology

    Mogus, L., Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 2019. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  43. Published

    Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer

    Flores-Morales, A., Bergmann, T. B., Lavallee, C., Batth, T. S., Lin, D., Lerdrup, M., Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, K., Røder, M. A., Brasso, K., Moreira, J. M., Bjartell, A., Wang, Y., Olsen, J. V., Collins, C. C. & 1 others, Iglesias Gato, Diego, 2019, In: Clinical Cancer Research. 25, 2, p. 1-15

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Purification of Functional Human TRP Channels Recombinantly Produced in Yeast

    Zhang, L., Wang, Kaituo, Klærke, Dan Arne, Callø, Kirstine, Lowrey, L., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2019, In: Cells. 8, 2, p. 1-20 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Retinal vessel diameters and systemic antioxidant capacity during hypoxia in patients with normal-tension glaucoma and individuals with ocular hypertension

    Langbøl, Mia Aggergaard, Baskaran, T., Tiedemann, D., Saruhanian, S., Toft-Kehler, A. K., Jensen, P. K., Jensen, P. S., Olsen, N. V., Vohra, Rupali & Kolko, Miriam, 2019. 2 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  46. Published

    SET domain containing 1B gene is mutated in primary hepatic neuroendocrine tumors

    Yang, P., Huang, X., Lai, C., Li, L., Li, T., Huang, P., Ouyang, S., Yan, J., Cheng, S., Lei, G., Wang, Z., Yu, L., Hong, Z., Li, R., Dong, H., Wang, C., Yu, Y., Wang, X., Li, X., Wang, L. & 7 others, Lv, F., Yin, Y., Yang, H., Song, J., Gao, Q., Wang, X. & Zhang, S., 2019, In: International Journal of Cancer. 145, 11, p. 2986-2995

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Sandwich cortial lamination and single-cell analysis decodes the developing spatial processing system

    Liu, Y., Bergmann, T. B., Lee, J., Pfisterer, U. G., Handfield, L-F., Mori, Y., Asenjo Martinez, A., Lisa Vargas, I., Seemann, E. S., Lee, J. T. H., Patikis, N., Peralvo Vidal, J. M., Pihl, M., Kornum, B. R., Thomsen, P. D., Hyttel, P., Witter, M., Khodosevich, K., Gorodkin, J., Hemberg, M. & 2 others, Pers, Tune H & Hall, Vanessa Jane, 2019. 45 p.

    Research output: Contribution to conference › Paper › Communication

  48. Published

    Simulated physiological oocyte maturation has side effects on bovine oocytes and embryos

    Razza, E. M., Pedersen, H. S., Stroebech, L., Fontes, P. K., Kadarmideen, H. N., Callesen, H., Pihl, M., Nogueira, M. F. G. & Hyttel, P., 2019, In: Journal of Assisted Reproduction and Genetics. 36, 3, p. 413–424

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Staphylococcus aureus infected embolic stroke upregulates Orm1 and Cxcl2 in a rat model of septic stroke pathology

    Astrup, L. B., Skovgaard, K., Rasmussen, Rune Skovgaard, Iburg, T. M., Agerholm, Jørgen Steen, Aalbæk, Bent, Jensen, Henrik Elvang, Nielsen, O. L., Johansen, F. F., Heegaard, P. M. H. & Leifsson, Páll S., 2019, In: Neurological Research. 41, 5, p. 399-412 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Stem cells on regenerative and reproductive science in domestic animals

    Pieri, N. C. G., de Souza, A. F., Botigelli, R. C., Machado, L. S., Ambrosio, C. E., dos Santos Martins, D., de Andrade, A. F. C., Meirelles, F. V., Hyttel, P. & Bressan, F. F., 2019, In: Veterinary Research Communications. 43, 1, p. 7-16 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    Structure of the human ClC-1 chloride channel

    Wang, Kaituo, Preisler, Sarah Spruce, Zhang, L., Cui, Y., Missel, Julie Winkel, Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.

    Research output: Contribution to journal › Journal article › Research › peer-review

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