Pathobiological Sciences

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  1. 2022
  2. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The Molecular target of oxantel in whipworms

    Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Callø, Kirstine, Courtot, E., Grencis, R., Issouf, M., Martin, R., Neveu, C. & Charvet, C., 2022.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  4. Published

    Treatment of implant-associated osteomyelitis with injectable in situ-forming depot drug delivery system

    Fuglsang-Madsen, A., Henriksen, Nicole Lind, Kvich, Lasse Andersson, Birch, Julie Knippel Melsted, Hartmann, Katrine Top, Bjarnsholt, Thomas, Andresen, T. L., Jensen, Louise Kruse, Henriksen, J. R. & Hansen, A. E., 2022.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  5. Published

    Tularæmi

    Hammer, Anne Sofie Vedsted, 2022, Risikovurdering af zoonotiske virus og andre agens, der kan forekomme i dyr og kan have epidemisk potentiale. Bødker, R., Kjær, L. J., Jokelainen, P., Trebbien, R., Boklund, A. & Larsen, L. E. (eds.). Københavns Universitet, p. 79-85 7 p.

    Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

  6. Published

    Urinary and plasma metabolome of farm mink (Neovison vison) after an intervention with raw or cooked poultry offal: a 1H NMR investigation

    Trimigno, A., Khakimov, Bekzod, Quaade, Michelle Lauge, Honoré, O. L., Clausen, T., Blaabjerg, K., Engelsen, Søren Balling & Hammer, Anne Sofie Vedsted, 2022, In: Archives of Animal Nutrition. 76, 1, p. 74-91

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Vectorborne zoonoses

    Bødker, René, Reipurth, M., Hammer, Anne Sofie Vedsted, Lohse, L. & Kjær, Lene Jung, 2022, Annual Report on Zoonoses in Denmark 2021. Olsen, A., Høg, B. B., Sandberg, M., Müller, L. & Torpdahl, M. (eds.). Technical University of Denmark, p. 17-20 (Annual Report on Zoonoses in Denmark, Vol. 2021).

    Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

  8. Published

    Virological and Histopathological Findings in Boars Naturally Infected With Porcine Reproductive and Respiratory Syndrome Virus Type 1

    Pedersen, K., Blirup-Plum, Sophie Amalie, Kristensen, C. S., Kvisgaard, L. K., Skade, L., Jensen, Henrik Elvang & Larsen, Lars, 2022, In: Frontiers in Microbiology. 13, 10 p., 874498.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet

    Skovsted, Gry Freja, Skat-Rørdam, Josephine, Frøkiær, A. P., Jensen, Henrik Elvang, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2022, In: Antioxidants. 11, 11, 2226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    “Non-healing” claw horn lesions in dairy cows: Clinical, histopathological and molecular biological characterization of four cases

    Alsaaod, M., Weber, J., Jensen, Tim Kåre, Brandt, S., Gurtner, C., Devaux, D., Studer, E. & Steiner, A., 2022, In: Frontiers in Veterinary Science. 9, 1041215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2021
  12. Published

    Forskningsfriheden i Danmark er under pres

    Albrechtsen, N. J. W., Andersen, P. E., Autzen, A., Bjørn, A., Damgaard, R. B., Burholt, L., Danbolt, M., Ellersgaard, C., Hansen, N. C., Jensen, L. K., Jensen, K. M. Ø., Jønsson, K., Kristensen, P. M., Kropp, K., Levisen, C., Møller, N. M., Nielsen, T. K., Laustsen, A. H., Nielsen, M. W., Simonsen, K. B. & 4 others, Sylow, Lykke, Vallgårda, Karen Asta Arnfred, Zetterberg-Nielsen, S. & Det Unge Akademi, D. U. A., 30 Oct 2021, In: Politiken. p. 5-6 2 p.

    Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication

  13. Published

    17 forskere: Udflytning splitter selve universitetsuddannelsernes DNA

    Jauffred, Liselotte, Albrechtsen, Nicolai Jacob Wewer, Bjørk, R., Dalsgaard, Peter Winstén, Damgaard, R. B., Dimke, H., Hansen, N. C., Jønsson, Knud Andreas, Kropp, K., Laustsen, A. H., Levisen, C., Jensen, Louise Kruse, Møller, Niels Martin, Nielsen, Mathias Wullum, Andersen, P. E., Sørensen, Thomas Just & Vallgårda, Karen Asta Arnfred, 15 Jun 2021, Altinget.dk.

    Research output: Other contribution › Communication

  14. Published

    Single-stage repair of tibial segmental bone defect with combined autograft, allograft and platelet-rich fibrin – case report

    Miles, James Edward, Gundersen, Ragnhild Skogstrøm & Jensen, Louise Kruse, 5 May 2021.

    Research output: Contribution to conference › Poster › Research › peer-review

  15. Published

    Påvisning af PRRSV/Materiale fra orner

    Kristensen, C. S., Kvisgaard, L. K., Blirup-Plum, Sophie Amalie, Skade, L., Pedersen, K., Jensen, Henrik Elvang & Larsen, Lars, 4 Feb 2021, SEGES Svineproduktion.

    Research output: Other contribution › Net publication - Internet publication › Communication

  16. Published

    Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins

    Preisler, Sarah Spruce, Wiuf, A. D., Friis, M., Kjaergaard, L., Hurd, M., Becares, E. R., Nurup, C. N., Bjoerkskov, F. B., Szathmáry, Z., Gourdon, Pontus Emanuel, Callø, Kirstine, Klærke, Dan Arne, Gotfryd, K. & Pedersen, Per Amstrup, 2021, In: Current research in structural biology. 3, p. 51-71 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A Static Bioimpedance and Dynamic Acoustic Myography Preliminary Assessment of Low Frequency Therapeutic Ultrasound Treatment of the Shoulder Muscle Trapezius: An Equine Study

    Isbell, D., Laguna, S. & Harrison, Adrian Paul, 2021, In: Open Journal of Veterinary Medicine. 11, 04, p. 125-135

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A comparative assessment of marker expression between cardiomyocyte differentiation of human induced pluripotent stem cells and the developing pig heart

    Lauschke, K., Volpini, L., Liu, Y., Vinggaard, A. M. & Hall, Vanessa Jane, 2021, In: Stem Cells and Development. 30, 7, p. 374-385

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A protein-centric view of in vitro biological model systems for schizophrenia

    Chandrasekaran, Abinaya, Jensen, P., Mohamed, Fadumo Abdullahi, Lancaster, M., Benros, Michael Eriksen, Larsen, M. R. & Freude, Kristine, 2021, In: Stem Cells. 39, 12, p. 1569-1578

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    APOE4 affects basal and NMDAR mediated protein synthesis in neurons by perturbing calcium homeostasis

    Ramakrishna, S., Jhaveri, V., Konings, S. C., Nawalpuri, B., Chakraborty, S., Holst, B., Schmid, B., Gouras, G. K., Freude, Kristine & Muddashetty, R. S., 2021, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 41, 42, p. 8686-8709

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Altered muscle activation in agility dogs performing warm-up exercises: an acoustic myography study

    Fuglsang-Damgaard, L. H., Harrison, Adrian Paul & Vitger, Anne Désiré, 2021, In: Comparative Exercise Physiology. 17, 3, p. 251-262 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    An Investigation Into the Short-Term Effects of Photobiomodulation on the Mechanical Nociceptive Thresholds of M. Longissimus and M. Gluteus Medius, in Relation to Muscle Firing Rate in Horses at Three Different Gaits

    Ahmed, W., Elbrønd (Bibs), Vibeke Sødring, Harrison, Adrian Paul, Hart, J. O. & Williams, R. E., 2021, In: Journal of Equine Veterinary Science. 98, 7 p., 103363.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Animal models in Mycology

    Jensen, Henrik Elvang & Barington, Kristiane, 2021, Handbook of laboratory animal science: Essential Principles and Practices. Hau, J. & Schapiro, SJ. (eds.). 4 ed. CRC Press, p. 695-722

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  24. Published

    Application of multi-omics data integration and machine learning approaches to identify epigenetic and transcriptomic differences between in vitro and in vivo produced bovine embryos

    Rabaglino, M. B., O’Doherty, A., Secher, Jan Bojsen-Møller, Lonergan, P., Hyttel, P., Fair, T. & Kadarmideen, H. N., 2021, In: PLoS ONE. 16, 5, 17 p., e0252096.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Artificial Intelligence-Based Quantification of Epithelial Proliferation in Mammary Glands of Rats and Oviducts of Göttingen Minipigs

    Hvid, H., Skydsgaard, M., Jensen, N. K., Viuff, B. M., Jensen, Henrik Elvang, Oleksiewicz, M. B. & Kvist, P. H., 2021, In: Toxicologic Pathology. 49, 4, p. 912-927

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3

    Chandrasekaran, A., Dittlau, K. S., Corsi, G. I., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Zhang, Y., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J. E., Kolko, M., Kobolák, J., Dinnyés, A., Hyttel, P., Palakodeti, D. & 5 others, Gorodkin, Jan, Muddashetty, R. S., Meyer, M., Aldana, Blanca & Freude, Kristine, 2021, In: Stem Cell Reports. 16, 11, p. 2736-2751

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Benzalkonium Chloride-Preserved Anti-Glaucomatous Eye Drops and Their Effect on Human Conjunctival Goblet Cells in vitro

    Nagstrup, Anne Hedengran, Begun, X., Müllertz, O., Mouhammad, Zaynab Ahmad, Vohra, Rupali, Bair, J., Dartt, D. A., Cvenkel, B., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2021, In: Biomedicine Hub. 6, 2, p. 69-75

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Blood glucose and subcutaneous continuous glucose monitoring in critically ill horses: A pilot study

    Vitale, V., Berg, Lise Charlotte, Larsen, B. B., Hannesdottir, A., Thomsen, Preben Dybdahl, Laursen, S. H., Verwilghen, D. & van Galen, G., 2021, In: PLoS ONE. 16, 2 February, e0247561.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Cellular bioenergetics in human iPSC-derived glutamatergic neurons in health and disease

    Aldana, Blanca, Salcedo, C., Freude, Kristine & Waagepetersen, Helle S., 2021, Current Progress in iPSC-derived Cell Types. Birbrair, A. (ed.). Elsevier, p. 205-221 17 p. (Advances in Stem Cell Biology, Vol. 10).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  30. Published

    Deep Myofascial Kinetic Lines in Horses, Comparative Dissection Studies Derived from Humans

    Elbrønd (Bibs), Vibeke Sødring & Schultz, R. M., 2021, In: Open Journal of Veterinary Medicine. 11, 01, p. 14-40

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Detecting bird’s eggs in the diet of raccoon dog (Nyctereutes procyonoides)

    Bahlke, S. Ø., Nash, David Richard, Pedersen, Jes Søe, Hansen, Mette Sif, Chriél, M. & Pagh, S., 2021, In: Genetics and Biodiversity Journal. 5, 2, p. 127-139 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Development of an aerogenous Escherichia coli infection model in adult broiler breeders

    Kromann, Sofie, Olsen, Rikke Heidemann, Bojesen, Anders Miki, Jensen, Henrik Elvang & Thoefner, Ida , 2021, In: Scientific Reports. 11, 15 p., 19556.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Development of the entorhinal cortex occurs via parallel lamination during neurogenesis

    Liu, Y., Bergmann, T., Mori, Yuki, Peralvo Vidal, Juan Miguel, Pihl, M., Vasistha, Navneet A, Thomsen, Preben Dybdahl, Seemann, Ernst Stefan, Gorodkin, Jan, Hyttel, P., Khodosevich, Konstantin, Witter, M. P. & Hall, Vanessa Jane, 2021, In: Frontiers in Neuroanatomy. 15, 19 p., 663667.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, Helle S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Early risk factors, development, disappearance and contents of umbilical outpouching in Danish pigs

    Hovmand-Hansen, T., Jensen, T. B., Vestergaard, K., Nielsen, M. B. F., Leifsson, Páll S. & Jensen, Henrik Elvang, 2021, In: Livestock Science. 251, 9 p., 104654.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Effect of age on the vascular proteome in middle cerebral arteries and mesenteric resistance arteries in mice

    Rabaglino, M. B., Wakabayashi, M., Pearson, J. T. & Jensen, Lars Jørn, 2021, In: Mechanisms of Ageing and Development. 200, 111594.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Enhanced Physiological Stress Response in Patients with Normal Tension Glaucoma during Hypoxia

    Dalgaard, L. M., Vibæk, J., Vohra, Rupali, Jensen, Lars Thorbjørn, Cvenkel, B., Secher, Niels H., Olsen, N. V. & Kolko, Miriam, 2021, In: Journal of Ophthalmology. 2021, 5826361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Epigenomic and transcriptomic analyses reveal early activation of the HPG axis in in vitro-produced male dairy calves

    Rabaglino, M. B., Secher, Jan Bojsen-Møller, Sirard, M. A., Hyttel, P. & Kadarmideen, H. N., 2021, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 35, 10, e21882.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Epigenomics and transcriptomics of muscle and liver tissues from in vitro- and in vivo-produced dairy calves at 3 months of age

    Rabaglino, M., Secher, Jan Bojsen-Møller, Hyttel, P. & Kadarmideen, H., 2021, In: Reproduction, fertility, and development. 34, 2, p. 316 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  40. Published

    Estimation of the age and reproductive performance of wild-born and escaped mink (Neovison vison) caught in the wild in Denmark

    Pagh, S., Pertoldi, C., Chriel, M., Petersen, H. H., Jensen, T. H., Madsen, S., Kraft, D. C. E., Schou, T. M. & Hansen, Mette Sif, 2021, In: Animals. 11, 1, 11 p., 162.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Evaluating a tylosin dosage regimen for treatment of Staphylococcus delphini infection in mink (Neovison vison): a pharmacokinetic-pharmacodynamic approach

    Ronaghinia, A. A., Birch, Julie Knippel Melsted, Frandsen, H. L., Toutain, P. L., Damborg, Peter Panduro & Struve, T., 2021, In: Veterinary Research. 52, 1, 16 p., 34.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Evaluation of electrocardiographic repolarization parameters after administration of trimethoprim-sulfadiazine, detomidine, or their combination in horses

    Trachsel, D. S., Callø, Kirstine, Jørgensen, Elin , Lunddahl, C. S., Pedersen, P. J., Kanters, Jørgen K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: American Journal of Veterinary Research. 82, 3, p. 207-217 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Exercise-Associated Sudden Death in Finnish Standardbred and Coldblooded Trotters - A Case Series With Pedigree Analysis

    Trachsel, D. S., Callø, Kirstine, Mykkänen, A. K., Raistakka, P., Anttila, M., Fredholm, Merete, Tala, M., Lamminpää, K., Klærke, Dan Arne & Buhl, Rikke, 2021, In: Journal of Equine Veterinary Science. 104, 103694.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Andersen, Jens Velde, Vinten, K. T., Pinborg, Lars Hageman, Waagepetersen, Helle S., Freude, Kristine & Aldana, Blanca, 2021, In: Frontiers in Aging Neuroscience. 13, 736580.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets

    Garcia Bermudez, Mariana Yolotzin, Freude, Kristine, Mouhammad, Zaynab Ahmad, van Wijngaarden, P., Martin, K. K. & Kolko, Miriam, 2021, In: Frontiers in Neurology. 12, 17 p., 624983.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, H., Westi, Emil Winther, Diaz-delCastillo, M., Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, Helle S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Histological examination of testes and epididymides from boars naturally infected with porcine reproductive and respiratory syndrome virus (PRRSV)

    Blirup-Plum, Sophie Amalie, Larsen, Lars, Jensen, Henrik Elvang, Kristensen, C. S. & Kvisgaard, L. K., 2021.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  48. Published

    Histopathology: Histopathological diagnosis using conventional staining techniques, with a key to identification

    Jensen, Henrik Elvang, Vonk, A. G., Verdijk, R., Boer, H. D., Lee, H. V. D. & Rijs, T., 2021, Atlas of clinical fungi: The ultimate benchtool for diagnostics. de Hoog, G. S., Guarro, J., Gené, J., Ahmed, S., Al-Hatmi, A. M. S., Figueras, M. J. & Vitale, R. G. (eds.). 4 ed. 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  49. Published

    Histopathology in the Diagnosis of Invasive Fungal Diseases

    Jensen, Henrik Elvang, 2021, In: Current Fungal Infection Reports. 15, 1, p. 23-31 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  50. Published

    Hornless cattle – is gene editing the best solution?

    Sandøe, Peter, Borchersen, S., Dean, Wesley, Hyttel, P., Sørensen, L. P. & Palmer, C., 2021, Justice and food security in a changing climate: EurSafe 2021, Fribourg, Switzerland, 24-26 June 2021. Schübel, H. & Wallimann-Helmer, I. (eds.). Wageningen Academic Publishers, p. 324-330 7 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  51. Published

    Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)

    Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, Nana Isabella, Ozgür, Burak, Holst, B., Shusta, E., Hall, Vanessa Jane, Saaby, Lasse, Hyttel, P. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism

    Okarmus, J., Havelund, J. F., Ryding, M., Schmidt, S. I., Bogetofte, H., Heon-Roberts, R., Wade-Martins, R., Cowley, S. A., Ryan, B. J., Færgeman, N. J., Hyttel, P. & Meyer, M., 2021, In: Stem Cell Reports. 16, 6, p. 1510-1526 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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