Pathobiological Sciences

  1. 2021
  2. Published

    Implant-associated osteomyelitis: Development, characterisation, and application of a porcine model

    Jensen, Louise Kruse, 2021, University of Copenhagen. 72 p.

    Research output: Book/ReportDoctoral thesisResearch

  3. Published

    Implant-associated osteomyelitis: Development, characterisation, and application of a porcine model

    Jensen, Louise Kruse, 2021, In: APMIS. 129, S141, p. 1-44 44 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Implications of Glycosylation in Alzheimer’s Disease

    Haukedal, H. & Freude, Kristine, 2021, In: Frontiers in Neuroscience. 14, 18 p., 625348.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Increased fibroblast accumulation in the equine heart following persistent atrial fibrillation

    Saljic, Arnela, Fenner, Merle Friederike, Winters, J., Flethøj, M., Eggert Eggertsen, C., Carstensen, Helena, Nissen, Sarah Dalgas, Melis Hesselkilde, E., van Hunnik, A., Schotten, U., Sørensen, U., Jespersen, Thomas, Verheule, S. & Buhl, Rikke, 2021, In: IJC Heart and Vasculature. 35, 100842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Infection, recovery and re-infection of farmed mink with SARS-CoV-2

    Rasmussen, T. B., Fonager, J., Jørgensen, C. S., Lassaunière, R., Hammer, Anne Sofie Vedsted, Quaade, Michelle Lauge, Boklund, Anette, Lohse, L., Strandbygaard, B., Rasmussen, M., Michaelsen, T. Y., Mortensen, S., Fomsgaard, A., Belsham, Graham John & Bøtner, A., 2021, In: PLOS Pathogens. 17, 11, e1010068.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells

    Schmidt, S. I., Bogetofte, H., Ritter, L., Agergaard, Jette Bach, Hammerich, D., Kabiljagic, A. A., Wlodarczyk, A., Lopez, S. G., Sørensen, M. D., Jørgensen, M. L., Okarmus, J., Serrano, A. M., Kristensen, Bjarne Winther, Freude, Kristine, Owens, T. & Meyer, M., 2021, In: Stem Cell Reports. 16, p. 1-14

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Molecular Techniques for Genus and Species Determination of Fungi From Fresh and Paraffin-Embedded Formalin-Fixed Tissue in the Revised EORTC/MSGERC Definitions of Invasive Fungal Infection

    Lockhart, S. R., Bialek, R., Kibbler, C. C., Cuenca-Estrella, M., Jensen, Henrik Elvang & Kontoyiannis, D. P., 2021, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 72, 2, p. S109-S113

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Molecular characterization of highly pathogenic avian influenza viruses h5n6 detected in denmark in 2018–2019

    Liang, Yuan, Krog, J. S., Ryt-Hansen, Pia, Pedersen, A. G., Kvisgaard, L. K., Holm, E., Nielsen, P. D., Hammer, Anne Sofie Vedsted, Madsen, Jesper Johannes, Thorup, Kasper, Larsen, Lars & Hjulsager, C. K., 2021, In: Viruses. 13, 6, 1052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Neural Derivates of Canine Induced Pluripotent Stem Cells-Like Cells From a Mild Cognitive Impairment Dog

    Chandrasekaran, Abinaya, Thomsen, B. B., Agerholm, Jørgen Steen, Pessôa, L. V. D. F., Godoy Pieri, N. C., Sabaghidarmiyan, V., Langley, K., Kolko, Miriam, De Andrade, A. F. C., Bressan, F. F., Hyttel, P., Berendt, Mette & Freude, Kristine, 2021, In: Frontiers in Veterinary Science. 8, 14 p., 725386.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Neuronal alpha-amylase is important for neuronal activity and glycogenolysis and reduces in presence of amyloid beta pathology

    Byman, E., Martinsson, I., Haukedal, H., Gouras, G., Freude, Kristine, Wennstrom, M. & Netherlands Brain Ban, N. B. B., 2021, In: Aging Cell. 20, 8, 14 p., 13433.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington’s Disease?

    Duque Villegas, Luisana Carolina, Nørremølle, Anne, Freude, Kristine & Vilhardt, Frederik, 2021, In: Frontiers in Aging Neuroscience. 13, 20 p., 736734.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction

    Tribble, J. R., Otmani, A., Sun, S., Ellis, S. A., Cimaglia, G., Vohra, R., Jöe, M., Lardner, E., Venkataraman, A. P., Domínguez-Vicent, A., Kokkali, E., Rho, S., Jóhannesson, G., Burgess, R. W., Fuerst, P. G., Brautaset, R., Kolko, M., Morgan, J. E., Crowston, J. G., Votruba, M. & 1 others, Williams, P. A., 2021, In: Redox Biology. 43, 21 p., 101988.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Non-immunogenic Induced Pluripotent Stem Cells, a Promising Way Forward for Allogenic Transplantations for Neurological Disorders

    Frederiksen, Henriette Reventlow S, Doehn, U., Tveden-Nyborg, Pernille & Freude, Kristine, 2021, In: Frontiers in Genome Editing. 2, 623717.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Oxidative stress in optic neuropathies

    Sanz-Morello, B., Ahmadi, H., Vohra, Rupali, Saruhanian, S., Freude, Kristine, Hamann, Steffen & Kolko, Miriam, 2021, In: Antioxidants. 10, 10, 27 p., 1538.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Post-weaning diarrhea in pigs weaned without medicinal zinc: risk factors, pathogen dynamics, and association to growth rate

    Eriksen, E. Ø., Kudirkiene, E., Christensen, A. E., Schmidt, Marianne Viuf Agerlin, Weber, N. R., Nødtvedt, A., Nielsen, Jens Peter, Hartmann, Katrine Top, Skade, L., Larsen, Lars, Pankoke, K., Olsen, John Elmerdahl, Jensen, Henrik Elvang & Pedersen, Ken Steen, 2021, In: Porcine Health Management. 7, 54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Preclinical testing of radiopharmaceuticals for the detection and characterization of osteomyelitis: Experiences from a porcine model

    Alstrup, A. K. O., Jensen, S. B., Nielsen, O. L., Jødal, L. & Afzelius, P., 2021, In: Molecules. 26, 14, 4221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Preliminary report of an outbreak of SARS-CoV-2 in mink and mink farmers associated with community spread, Denmark, June to November 2020

    Larsen, H. D., Fonager, J., Lomholt, F. K., Dalby, T., Benedetti, G., Kristensen, B., Urth, T. R., Rasmussen, M., Lassaunière, R., Rasmussen, T. B., Strandbygaard, B., Lohse, L., Chaine, M., Møller, K. L., Berthelsen, A. S. N., Nørgaard, S. K., Sönksen, U. W., Boklund, A. E., Hammer, A. S., Belsham, G. J. & 5 others, Krause, Tyra Grove, Mortensen, S., Bøtner, A., Fomsgaard, A. & Mølbak, Kåre, 2021, In: Eurosurveillance. 26, 5, 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published
  20. Published

    Quantitative proteome comparison of human hearts with those of model organisms

    Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    RT-qPCR assay for detection of mink astrovirus in outbreaks of diarrhea on Danish mink farms

    Barsøe, S., Ullman, K., Leijon, M., Hedlund, K. O., Klingström, J., Krarup, L. I., Andresen, Lars, Quaade, Michelle Lauge & Hammer, Anne Sofie Vedsted, 2021, In: PLoS ONE. 16, 5, e0252022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    SARS-CoV-2 in Danish Mink Farms: Course of the Epidemic and a Descriptive Analysis of the Outbreaks in 2020

    Boklund, Anette, Hammer, Anne Sofie Vedsted, Quaade, Michelle Lauge, Rasmussen, T. B., Lohse, L., Strandbygaard, B., Jørgensen, C. S., Olesen, A. S., Hjerpe, F. B., Petersen, H. H., Jensen, Tim Kåre, Mortensen, S., Calvo-Artavia, F. F., Lefèvre, S. K., Nielsen, Søren Saxmose, Halasa, T., Belsham, Graham John & Bøtner, A., 2021, In: Animals. 11, 1, p. 1-16 16 p., 164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    SARS-CoV-2 transmission between mink (neovison vison) and Humans, Denmark

    Hammer, Anne Sofie Vedsted, Quaade, Michelle Lauge, Rasmussen, T. B., Fonager, J., Rasmussen, M., Mundbjerg, K., Lohse, L., Strandbygaard, B., Jørgensen, C. S., Alfaro-Núñez, A., Rosenstierne, M. W., Boklund, Anette, Halasa, T., Fomsgaard, A., Belsham, Graham John & Bøtner, A., 2021, In: Emerging Infectious Diseases . 27, 2, p. 547-551 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The Development of Contractures in Cerebral Palsy and Stroke: Pathophysiological Approaches

    Pingel, Jessica, Harrison, Adrian Paul, Korbo, L. & Bartels, E., 2021, In: Journal of Clinical and Experimental Neuroimmunology. 6, 4, 5 p., 1000127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The Effect of Aromatherapy on Equine Facial Expression, Heart Rate, Respiratory Tidal Volume and Spontaneous Muscle Contractures in M. Temporalis and M. Cleidomastoideus

    Kosiara, S. & Harrison, Adrian Paul, 2021, In: Open Journal of Veterinary Medicine. 11, 02, p. 87-103

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The effect of antimicrobial treatment on mortality associated with urinary tract disease in mink kits (Neovison vison)

    Mundbjerg, K., Pedersen, P. E. & Hammer, Anne Sofie Vedsted, 2021, In: Acta Veterinaria Scandinavica. 63, 1, 6 p., 15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The impact of water depth and speed on muscle fiber activation of healthy dogs walking in a water treadmill

    Vitger, Anne Désiré, Bruhn-Rasmussen, T., Pedersen, E. O., Fuglsang-Damgaard, L. H. & Harrison, Adrian Paul, 2021, In: Acta Veterinaria Scandinavica. 63, 1, 46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The narrow-spectrum anthelmintic oxantel is a potent agonist of a novel acetylcholine receptor subtype in whipworms

    Hansen, Tina Vicky Alstrup, Cirera, Susanna, Neveu, C., Courtot, E., Charvet, C. L., Callø, Kirstine, Klærke, Dan Arne & Martin, R. J., 2021, In: P L o S Pathogens. 17, 2, 26 p., e1008982.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Vascular calcium signaling and aging

    Harraz, O. F. & Jensen, Lars Jørn, 2021, In: The Journal of Physiology. 599, 24, p. 5361-5377

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Visualization of intestinal infections with astro- and sapovirus in mink (Neovison vison) kits by in situ hybridization

    Birch, Julie Knippel Melsted, Leijon, M., Nielsen, Søren Saxmose, Struve, T. & Jensen, Henrik Elvang, 2021, In: FEMS Microbes. 2, 6 p., xtab005.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Visualization of intestinal infections with astro- and sapovirus in mink (nevison vison) kits by in situ hybridization

    Birch, Julie Knippel Melsted, Leijon, M., Nielsen, Søren Saxmose, Struve, T. & Jensen, Henrik Elvang, 2021, In: FEMS Microbes. 2, 6 p., xtab005.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Vitrification yields higher cryo-survival rate than slow freezing in biopsied bovine in vitro produced blastocysts

    Najafzadeh, Vahid, Secher, Jan Bojsen-Møller, Pihl, M., Ærenlund, A., Jørgensen, N., Jensen, K. K., Jensen, M. T., Fenner, Merle Friederike, Strøbech, L. & Hyttel, P., 2021, In: Theriogenology. 171, p. 44-54 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    When is a control not a control? Reactive microglia occur throughout the control contralateral pathway of retinal ganglion cell projections in experimental glaucoma

    Tribble, J. R., Kokkali, E., Otmani, A., Plastino, F., Lardner, E., Vohra, Rupali, Kolko, Miriam, André, H., Morgan, J. E. & Williams, P. A., 2021, In: Translational Vision Science and Technology. 10, p. 1-23 23 p., 22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    iPSC-derived Microglia for Disease Modeling of Frontotemporal Dementia 3

    Haukedal, H., Freude, Kristine, Garcia, B. A., Corsi, G., Gadekar, V. & Gorodkin, Jan, 2021, In: Glia. 69, S1, p. E480-E481 T14-066D.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. 2020
  36. Published

    Patient iPSC-Derived Neorons for Disease Modeling of Familiar Alzheimer's Disease with Mutations in Presenilin 1

    Haukedal, H., Poon, A. F., Jensen, P., Aldana, Blanca, Pires, C., Chandrasekaran, Abinaya, Christensen, S. K., Schiønning, P., Vallin, S., Simonsen, A. H., Nielsen, J., Dinnyes, A., Gorodkin, Jan, Ramakrishna, S., Muddashetty, R., Palakodeti, D., Hyttel, P., Waagepetersen, Helle S., Larsen, M. R. & Freude, Kristine, Oct 2020.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  37. Published

    Canine induced pluripotent stem cells: an in vitro approach to validate the dog as a large animal model for Alzheimer's disease

    Pessoa, L. V. D. F., Chandrasekaran, Abinaya, Thomsen, B. B., Berendt, Mette, Hyttel, P. & Freude, Kristine, Sep 2020, iPSCs from Diverse Species. 1 ed. Elsevier: Academic Press, Vol. 2.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  38. Published

    Mammorna tog ansvaret hemma när skolorna stängde

    Leijnse, E. & Hall, Vanessa Jane, 6 Aug 2020

    Research output: Other contributionNet publication - Internet publicationCommunication

  39. Published

    European Forensic Veterinary Pathology Comes of Age

    Munro, R., Ressel, L., Gröne, A., Hetzel, U., Jensen, Henrik Elvang, Paciello, O. & Kipar, A., 1 Aug 2020, In: Journal of Comparative Pathology. 179, p. 83-88 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    A Novel Promazine Derivative Shows High in vitro and in vivo Antimicrobial Activity Against Staphylococcus aureus

    Ronco, T., Jørgensen, N. S., Holmer, I., Kromann, Sofie, Sheikhsamani, E., Permin, A., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad & Olsen, Rikke Heidemann, 2020, In: Frontiers in Microbiology. 11, 12 p., 560798.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A community-based transcriptomics classification and nomenclature of neocortical cell types

    Yuste, R., Hawrylycz, M., Aalling, N., Aguilar-valles, A., Arendt, D., Arnedillo, R. A., Ascoli, G. A., Bielza, C., Bokharaie, V., Bergmann, T. B., Bystron, I., Capogna, M., Chang, Y., Clemens, A., De Kock, C. P. J., Defelipe, J., Dos Santos, S. E., Dunville, K., Feldmeyer, D., Fiáth, R. & 53 others, Fishell, G. J., Foggetti, A., Gao, X., Ghaderi, P., Goriounova, N. A., Güntürkün, O., Hagihara, K., Hall, Vanessa Jane, Helmstaedter, M., Herculano, S., Hilscher, M. M., Hirase, Hajime, Hjerling-leffler, J., Hodge, R., Huang, J., Huda, R., Khodosevich, Konstantin, Kiehn, Ole, Koch, H., Kuebler, E. S., Kühnemund, M., Larrañaga, P., Lelieveldt, B., Louth, E. L., Lui, J. H., Mansvelder, H. D., Marin, O., Martinez-trujillo, J., Moradi Chameh, H., Nath, A., Nedergaard, M., Němec, P., Ofer, N., Pfisterer, U. G., Pontes, S., Redmond, W., Rossier, J., Sanes, J. R., Scheuermann, R., Serrano-saiz, E., Steiger, J. F., Somogyi, P., Tamás, G., Tolias, A. S., Tosches, M. A., García, M. T., Vieira, H. M., Wozny, C., Wuttke, T. V., Yong, L., Yuan, J., Zeng, H. & Lein, E., 2020, In: Nature Neuroscience. 23, p. 1456-1468 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    A non-invasive assessment of ground reaction forces in the human leg in response to walking, jogging, running and jumping

    Pingel, Jessica & Harrison, Adrian Paul, 2020, In: Open Journal of Orthopedics. 10, 7, p. 152-160

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    A novel derivative of thioridazine shows low toxicity and efficient activity against gram‐positive pathogens

    Jørgensen, N. S., Saaby, Lasse, Andersson, A. M., Kromann, Sofie, Sheikhsamani, E., Permin, A., Ronco, T., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad & Olsen, Rikke Heidemann, 2020, In: Antibiotics. 9, 6, 11 p., 327.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Acoustic Myography in Assessment of Isokinetic and Isometric Muscle Strength in a Healthy Danish Population

    Bartels, E. M., Ahmed, W., Olsen, J. K., Andersen, E. L., Danneskiold-samsøe, B., Kristensen, Lars Erik Vølund, Bliddal, Henning, Bartholdy, C. R. & Harrison, Adrian Paul, 2020, In: Journal of Biomedical Science and Engineering. 13, 12, p. 235-253

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Aging, calcium channel signaling and vascular tone

    Harraz, O. F. & Jensen, Lars Jørn, 2020, In: Mechanisms of Ageing and Development. 191, 5 p., 111336.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    An Investigation into Cold-Therapy of the Equine Metacarpus, Following Temperature Changes with Exercise as Well as Post Intervention

    Nielsen, S. B., Madvig, C. B. & Harrison, Adrian Paul, 2020, In: Open Journal of Veterinary Medicine. 10, 10, p. 185-194

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Association between Fur Animal Necrotizing Pyoderma in breeding farm mink (Neovison vison) and reduced fertility

    Honoré, O. L., Sebbelov, I., Wallin, A., Petersen, A., Clausen, T., Larsen, P. F. & Hammer, Anne Sofie Vedsted, 2020, In: Acta Veterinaria Scandinavica. 62, 1, 66.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Attempts to Target Staphylococcus aureus Induced Osteomyelitis Bone Lesions in a Juvenile Pig Model by Using Radiotracers

    Afzelius, P., Alstrup, A. K. O., Nielsen, O. L., Nielsen, K. M. & Jensen, S. B., 2020, In: Molecules. 25, 18, p. 4329 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Bovine in-vitro produced embryos: Development of embryo proper and associated membranes from day 26 to 47 of gestation

    Pedersen, H. S., Mazzoni, G., Pihl, M., Kadarmideen, H. N., Hyttel, P. & Callesen, H., 2020, In: Reproductive Biology. 20, 4, p. 595-599

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Canine induced pluripotent stem cells: An in vitro approach to validate the dog as a large animal model for Alzheimer’s disease

    De Figueiredo Pessôa, L. V., Chandrasekaran, Abinaya, Thomsen, B. B., Berendt, Mette, Hyttel, P. & Freude, Kristine, 2020, iPSCs from Diverse Species. Academic Press, p. 77-91 15 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  51. Published

    Characterization of the endometrial transcriptome in early diestrus influencing pregnancy status in dairy cattle after transfer of in vitro-produced embryos

    Mazzoni, G., Pedersen, H. S., Rabaglino, M. B., Hyttel, P., Callesen, H. & Kadarmideen, H. N., 2020, In: Physiological Genomics. 52, 7, p. 269-279 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Cloning and Expression of an Oxantel Sensitive Homomeric Nicotinic Acetylcholine Receptor of Trichuris, the Tsu-ACR-16-like receptor

    Hansen, Tina Vicky Alstrup, Klærke, Dan Arne, Cirera, Susanna, Neveu, C., Callø, Kirstine & Martin, R., 2020.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

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