Pathobiological Sciences

  1. 2024
  2. Published

    Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy

    Kamand, M., Taleb, R., Wathikthinnakon, Methi, Mohamed, Fadumo Abdullahi, Ghanzanfari, S. P., Konstantinov, D., Hald, Jonas Laugård, Holst, B., Andersen, C. B., Møller, R. S., Lemke, J. R., Krey, I., Freude, Kristine & Chandrasekaran, Abinaya, 1 Apr 2024, In: Stem Cell Research. 76

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Astrocytes: The Stars in Neurodegeneration?

    Dittlau, Katarina Stoklund & Freude, Kristine, 28 Feb 2024, In: Biomolecules.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Functional, Structural and Proteomic Effects of Ageing in Resistance Arteries

    Jensen, Lars Jørn, 23 Feb 2024, 22 p. MDPI - Open Access Publishing.

    Research output: Other contributionResearch

  5. Published

    The loss-of-function variant p.M764R in the cardiac sodium channel Nav1.5 is associated with ventricular arrhythmias and sudden cardiac death in a family without overt Brugada syndrome

    Callø, Kirstine, Christiansen, M. K., Henriksen, F. L. & Jensen, H. K., Feb 2024, In: HeartRhythm Case Reports. 10, 2, p. 137-141 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Implications of SNP-triggered miRNA dysregulation in Schizophrenia development

    Mohamed, Fadumo Abdullahi & Freude, Kristine, 26 Jan 2024, In: Frontiers in Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    USP30 inhibition induces mitophagy and reduces oxidative stress in parkin-deficient human neurons

    Okarmus, J., Agergaard, J. B., Stummann, T., Haukedal, H., Ambjørn, M., Freude, Kristine, Fog, K. & Meyer, M., 14 Jan 2024, In: Nature.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Atrial fibrillation as a risk factor for exercise-induced pulmonary haemorrhage following a standardised exercise test

    Hansen, Sanni, Dam Otten, Nina, Nissen, Sarah Dalgas, Carstensen, Helena, Hopster-Iversen, Charlotte, Fjeldborg, Julie, Staun, S. H., Fenner, Merle Friederike, Hesselkilde, E. M. & Buhl, Rikke, 2024, In: Equine Veterinary Journal. 56, 3, p. 552-561

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Catheter-associated bladder mucosal trauma during intermittent voiding: An experimental study in pigs

    Stærk, K., Schrøder, B., Jensen, Louise Kruse, Petersen, T., Andersen, T. E. & Nielsen, L. F., 2024, In: BJUI Compass. 5, 2, p. 217-223 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Charting the Explicit Path: Translational Dynamics of Hepatic Bioengineering from Experimental Benchmarks to Practical Bedside Applications

    Radhakrishnan, S., Martin, C. A., Dhayanithy, G., Martin, J. C., Chandrasekaran, Abinaya, Kalkura, S. N. & Rela, M., 2024, In: MedLiber of Regenerative Medicine. 2, 1, p. 1-18

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Clinicopathologic evaluation of congenital idiopathic megaesophagus in a Gordon Setter puppy: a case report and development and application of peripherin immunohistochemistry for detection of ganglion cells

    Becker, Cecilie Brandt & Jensen, Henrik Elvang, 2024, In: Journal of Veterinary Diagnostic Investigation. 36, 2, p. 254-257 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Distinct Metabolic Profiles of Ocular Hypertensives in Response to Hypoxia

    Langbøl, Mia Aggergaard, Rovelt, Jens, Saruhanian, A., Saruhanian, S., Tiedemann, D., Baskaran, T., Bocca, C., Vohra, Rupali, Cvenkel, B., Lenaers, G. & Kolko, Miriam, 2024, In: International Journal of Molecular Sciences. 25, 1, 18 p., 195.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Effect on calf growth of accounting for early in vitro degradation kinetics when composing a calf starter ration

    Sembach, Lasse Emil, Nielsen, L. R. H., Jensen, M. M., Dhakal, Rajan & Hansen, Hanne Helene, 2024, In: Livestock Science. 283, 8 p., 105459.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. E-pub ahead of print

    Equine dental sinusitis—A statistical analysis of the effect of antibiotics on dental sinusitis following dental extraction

    Lydiksen, C. V., Christensen, J. I., Rosenmeier, J. G., Jensen, Dan Børge & Lindegaard, Casper, 2024, (E-pub ahead of print) In: Equine Veterinary Education.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Accepted/In press

    Eradication of Staphylococcus aureus in Implant-Associated Osteomyelitis by an Injectable in situ-Forming Depot Antibiotics Delivery System

    Fuglsang-Madsen, A. J., Henriksen, Nicole Lind, Chávez, E. S., Kvich, Lasse Andersson, Birch, Julie Knippel Melsted, Hartmann, Katrine Top, Eriksen, Thomas, Bjarnsholt, Thomas, Gottlieb, Hans, Andresen, T. L., Jensen, Louise Kruse, Henriksen, J. R. & Hansen, A. E., 2024, (Accepted/In press) In: The Journal of Infectious Diseases.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies

    Dittlau, Katarina Stoklund, Chandrasekaran, Abinaya, Freude, Kristine & Van Den Bosch, L., 2024, In: Bio-protocol. 14, 4, 16 p., e4936.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus

    Duque Villegas, Luisana Carolina, Chandrasekaran, Abinaya, Flintholm Andersen, S. A., Nørremølle, Anne, Schmid, B., Pouladi, M. A. & Freude, Kristine, 2024, In: Stem Cell Research. 77, 6 p., 103408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    High fat diet is associated with gut microbiota dysbiosis and decreased gut microbial derived metabolites related to metabolic health in young Göttingen Minipigs

    Lützhøft, Ditte Olsen, Bækgård, Cecilie, Wimborne, E., Straarup, E. M., Pedersen, K. M., Swann, J. R., Pedersen, H. D., Kristensen, K., Morgills, L., Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Bracken, M. K., Cirera, Susanna & Christoffersen, B. Ø., 2024, In: PLoS ONE. 19, 3, 27 p., e0298602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. E-pub ahead of print

    Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease

    Salcedo, C., Pozo Garcia, V., Garcia-Adan, B., Ameen, Aisha, Gegelashvili, G., Waagepetersen, Helle S., Freude, Kristine & Aldana, Blanca, 2024, (E-pub ahead of print) In: Journal of Neurochemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published
  21. Published

    Migratory pattern of zoonotic Toxocara cati and T. canis in experimentally infected pigs

    Poulsen, C. S., Yoshida, A., Wellbrant, T. T., Leifsson, Páll S., Skallerup, P., Thamsborg, Stig Milan & Nejsum, P., 2024, In: European Journal of Clinical Microbiology and Infectious Diseases. 43, p. 587-596 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Pathological Diagnosis of Pulmonary Aspergillosis

    Jensen, Henrik Elvang & Becker, Cecilie Brandt, 2024, In: Seminars in Respiratory and Critical Care Medicine. 45, 1, p. 41-49

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Rifampicin does not reduce moxifloxacin concentrations at the site of infection and may not improve treatment outcome of a one-stage exchange surgery protocol of implant-associated osteomyelitis lesions in a porcine model

    Vittrup, S., Jensen, Louise Kruse, Hartmann, Katrine Top, Aalbæk, Bent, Hanberg, P., Slater, J., Hvistendahl, M. A., Stilling, M., Jørgensen, N. P. & Bue, M., 2024, In: APMIS. 132, 3, p. 198-209 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The avian influenza A virus receptor SA-α2,3-Gal is expressed in the porcine nasal mucosa sustaining the pig as a mixing vessel for new influenza viruses

    Kristensen, Charlotte, Larsen, Lars, Trebbien, R. & Jensen, Henrik Elvang, 2024, In: Virus Research. 340, 8 p., 199304.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2023
  26. Published

    Complexity of Sex Differences and Their Impact on Alzheimer’s Disease

    Kadlecová, Marion, Freude, Kristine & Haukedal, H., 24 Apr 2023, In: Biomedicines. 11, 5, 29 p., 1261.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    3D-organization and spatial localization of chromatin and epigenetic marks in relation to nucleolar activity in porcine oocytes

    Fenner, Merle Friederike, Benc, M., Rosenbaum Bartkova , A., Pihl, M., Chebrout, M., Freude, Kristine, Strejeck, F., Hyttel, P., Lucas-Hahn, A., Laurincik, J. & Bonnet-Garnier, A., 2023. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

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