Dexamethasone treatment affects skin mucous cell density in Gyrodactylus derjavini infected Salmo salar
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Dexamethasone treatment affects skin mucous cell density in Gyrodactylus derjavini infected Salmo salar. / Olafsdottir, S. H.; Buchmann, K.
I: Journal of Helminthology, Bind 78, Nr. 1, 03.2004, s. 87-90.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Dexamethasone treatment affects skin mucous cell density in Gyrodactylus derjavini infected Salmo salar
AU - Olafsdottir, S. H.
AU - Buchmann, K.
PY - 2004/3
Y1 - 2004/3
N2 - Atlantic salmon, Salmo salar, is normally rather refractive to infection with the ectoparasitic monogenean Gyrodactylus derjavini but dexamethasone treatment of the host increases the susceptibility. The causative mechanisms were elucidated in this work. Groups of Atlantic salmon were treated by intra-peritoneal dexamethasone injections and subsequently infected with G. derjavini. It was shown that both the infection level and the mucous cell density of caudal and pelvic fins were affected by the treatment. Significantly higher mucous cell densities were found on infected and treated fish whereas non-infected and treated fish showed no significant elevation of cell density. This suggests that mucous cell discharge elicited by infection is inhibited by the drug. The association with elevated parasite counts in these fish can be explained either by decreased anti-parasitic mucus action or by parasite predilection for intact mucous cells.
AB - Atlantic salmon, Salmo salar, is normally rather refractive to infection with the ectoparasitic monogenean Gyrodactylus derjavini but dexamethasone treatment of the host increases the susceptibility. The causative mechanisms were elucidated in this work. Groups of Atlantic salmon were treated by intra-peritoneal dexamethasone injections and subsequently infected with G. derjavini. It was shown that both the infection level and the mucous cell density of caudal and pelvic fins were affected by the treatment. Significantly higher mucous cell densities were found on infected and treated fish whereas non-infected and treated fish showed no significant elevation of cell density. This suggests that mucous cell discharge elicited by infection is inhibited by the drug. The association with elevated parasite counts in these fish can be explained either by decreased anti-parasitic mucus action or by parasite predilection for intact mucous cells.
U2 - 10.1079/JOH2003206
DO - 10.1079/JOH2003206
M3 - Journal article
C2 - 14972042
AN - SCOPUS:1642341165
VL - 78
SP - 87
EP - 90
JO - Journal of Helminthology
JF - Journal of Helminthology
SN - 0022-149X
IS - 1
ER -
ID: 247150846