Increased susceptibility of Atlantic salmon Salmo salar to infections with Gyrodactylus derjavini induced by dexamethasone bath treatment
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Increased susceptibility of Atlantic salmon Salmo salar to infections with Gyrodactylus derjavini induced by dexamethasone bath treatment. / Nielsen, C. V.; Buchmann, K.
I: Journal of Helminthology, Bind 77, Nr. 1, 03.2003, s. 65-68.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Increased susceptibility of Atlantic salmon Salmo salar to infections with Gyrodactylus derjavini induced by dexamethasone bath treatment
AU - Nielsen, C. V.
AU - Buchmann, K.
PY - 2003/3
Y1 - 2003/3
N2 - Dexamethasone, a known immunosuppressant, was administered by bath or injection to Atlantic salmon Salmo salar (Conon stock) to study if this treatment could affect the susceptibility of fish to infections with a Danish strain of Gyrodactylus derjavini (Monogenea). Three groups of S. salar (Conon stock) were immersion treated either with 10, 60 or 240 μg dexamethasone 1-1 water, respectively. In addition, one group (positive control) was treated intraperitoneally with 200 μg dexamethasone per fish and one negative control group was kept untreated. A single G. derjavini parasite was placed on the anal fin of each fish and the infection was subsequently monitored weekly for 6 weeks. An increase in parasite populations on the salmon was positively correlated with the amount of immunosuppressant used. Infection levels in the group immersion treated with dexamethasone (240 μg1-1 water) and in the i.p. treated positive control group were significantly higher compared to the untreated control group.
AB - Dexamethasone, a known immunosuppressant, was administered by bath or injection to Atlantic salmon Salmo salar (Conon stock) to study if this treatment could affect the susceptibility of fish to infections with a Danish strain of Gyrodactylus derjavini (Monogenea). Three groups of S. salar (Conon stock) were immersion treated either with 10, 60 or 240 μg dexamethasone 1-1 water, respectively. In addition, one group (positive control) was treated intraperitoneally with 200 μg dexamethasone per fish and one negative control group was kept untreated. A single G. derjavini parasite was placed on the anal fin of each fish and the infection was subsequently monitored weekly for 6 weeks. An increase in parasite populations on the salmon was positively correlated with the amount of immunosuppressant used. Infection levels in the group immersion treated with dexamethasone (240 μg1-1 water) and in the i.p. treated positive control group were significantly higher compared to the untreated control group.
U2 - 10.1079/JOH2002159
DO - 10.1079/JOH2002159
M3 - Journal article
C2 - 12590667
AN - SCOPUS:0037342542
VL - 77
SP - 65
EP - 68
JO - Journal of Helminthology
JF - Journal of Helminthology
SN - 0022-149X
IS - 1
ER -
ID: 247151081