Dorte Frees

Dorte Frees

Associate Professor

Member of:


    1. 2012
    2. Published

      Norlichexanthone modulate Staphylococcus aureus virulence gene expression possibly via agr and sae

      Nielsen, A., Ifrah, D., Friberg, C., Larsen, T. O., Novick, R. P., Frøkiær, Hanne, Frees, Dorte, Hede, N. G. & Ingmer, Hanne, 2012.

      Research output: Contribution to conferencePosterResearch

    3. Published

      Pathology and biofilm formation in a porcine model of staphylococcal osteomyelitis

      Johansen, L. K., Koch, J., Frees, Dorte, Aalbæk, Bent, Nielsen, O. L., Leifsson, Páll S., Iburg, T. M., Svalastoga, Eiliv Lars, Buelund, Lene Elisabeth, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Henrik Elvang, 2012, In: Journal of Comparative Pathology. 147, 2-3, p. 343-353 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Planktonic aggregates of Staphylococcus aureus protect against common antibiotics

      Haaber, J. K., Cohn, M. T., Frees, Dorte, Andersen, Thorbjørn Joest & Ingmer, Hanne, 2012, In: P L o S One. 7, 7, 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      The YjbH adaptor protein enhances proteolysis of the transcriptional regulator Spx in Staphylococcus aureus

      Engman, J., Rogstam, A. H., Frees, Dorte, Ingmer, Hanne & Wachenfeldt, C. V., 2012, In: Journal of Bacteriology. 194, 5, p. 1186-1194 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. 2011
    7. Published

      A porcine model of acute, haematogenous, localized osteomyelitis due to Staphylococcus aureus: a pathomorphological study

      Jensen, Louise Kruse, Frees, Dorte, Aalbæk, Bent, Koch, J., Iburg, T. M., Nielsen, O. L., Leifsson, Páll S. & Jensen, Henrik Elvang, 2011, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 119, 2, p. 111-118 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Clp-dependent proteolysis of the LexA N-terminal domain in Staphylococcus aureus

      Cohn, M. T., Kjelgaard, P. M., Frees, Dorte, Penadés, J. R. & Ingmer, Hanne, 2011, In: Microbiology. 157, 3, p. 677-684 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Expression and secretion of the RTX-toxin GtxA among members of the genus Gallibacterium

      Kristensen, B. M., Frees, Dorte & Bojesen, Anders Miki, 2011, In: Veterinary Microbiology. 153, 1-2, p. 116-123 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Searching for small sB-regulated genes in Staphylococcus aureus

      Nielsen, J. S., Christiansen, M. H. G., Bonde, M., Gottschalk, S., Frees, Dorte, Thomsen, Line Elnif & Kallipolitis, B. H., 2011, In: Archives of Microbiology. 193, 1, p. 23-34 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. 2010
    12. Published

      A hitherto not recognized phenotype of spvA in Salmonella

      Frees, Dorte, Gram, L., Holmstrøm, K. & Olsen, John Elmerdahl, 2010, Proceedings: 13S international symposium salmonella and salmonellosis. p. 33-34 2 p.

      Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

    13. Published

      Distribution, expression and secretion of the RTX-toxin GtxA among members of the genus Gallibacterium

      Kristensen, B. M., Frees, Dorte & Bojesen, Anders Miki, 2010, Pathogenesis of bacterial diseases in animals. p. 22 1 p.

      Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

    14. Published

      Growth phase-dependent regulation of the global virulence regulator Rot in clinical isolates of Staphylococcus aureus

      Jelsbak, L., Hemmingsen, L., Donat, S., Ohlsen, K., Boye, K., Westh, H., Ingmer, Hanne & Frees, Dorte, 2010, In: International Journal of Medical Microbiology. 300, 4, p. 229-236 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      GtxA from Gallibacterium anatis, a cytolytic RTX-toxin with a novel domain organisation

      Kristensen, B. M., Frees, Dorte & Bojesen, Anders Miki, 2010, In: Veterinary Research. 41, 25, 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Method for screening compounds that influence virulence gene expression in Staphylococcus aureus

      Nielsen, A., Nielsen, K. F., Frees, Dorte, Larsen, T. O. & Ingmer, Hanne, 2010, In: Antimicrobial Agents and Chemotherapy. 54, 1, p. 509-512 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      PhD course "Infection Microbiology": time schedule for module A, 2010

      Frees, Dorte, Nielsen, M. & Thomsen, Line Elnif, 2010, Department of Veterinary Disease Biology, University of Copenhagen. 72 p.

      Research output: Book/ReportCompendium/lecture notesEducation

    18. Published

      The chaperone ClpX stimulates expression of Staphylococcus aureus protein A by rot dependent and independent pathways

      Jelsbak, L., Ingmer, Hanne, Valihrach, L., Cohn, M. T., Christiansen, M. H. G., Kallipolitis, B. H. & Frees, Dorte, 2010, In: PLoS ONE. 5, 9, 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. 2009
    20. Published

      The role of Spi-6 and a putative type six secretion system in Salmonella serotype Gallinarum virulence

      Olsen, John Elmerdahl, Kristensen, B. M. & Frees, Dorte, 2009, ASM conference on Salmonella: Biology, Pathogenesis & Prevention. p. 50 1 p.

      Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

    21. 2008
    22. Published

      Investigation of correlation between gene expressions of 162 selected genes and survival and colonization abilities of Salmonella strains in the food chain

      Olsen, John Elmerdahl, Gram, L., Frees, Dorte & Holmstrøm, K., 2008, The 21st International ICFMH Symposium "Evolving Microbial Food Quality and Safety": Programme and Abstract Book. p. 164 1 p.

      Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

    23. Published

      Simple plate assay for identification of new compounds used in anti-virulence therapy of Staphylococcus aureus

      Nielsen, A., Nielsen, K. F., Frees, Dorte, Larsen, T. O. & Ingmer, Hanne, 2008. 1 p.

      Research output: Contribution to conferencePaperResearchpeer-review

    24. Published

      Simple plate assay for identification of new compounds used in anti-virulence therapy of Staphylococcus aureus

      Nielsen, A., Nielsen, K. F., Frees, Dorte, Larsen, T. O. & Ingmer, Hanne, 2008.

      Research output: Contribution to conferencePosterResearch

    25. Published

      Simple plate assay for identification of new compounds used in anti-virulence therapy of Staphylococcus aureus

      Nielsen, A., Nielsen, K. F., Frees, Dorte, Larsen, T. O. & Ingmer, Hanne, 2008.

      Research output: Contribution to conferencePosterResearch

    26. 2007
    27. Published

      Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram-positive bacteria

      Frees, Dorte, Savijoki, K., Varmanen, P. & Ingmer, Hanne, 2007, In: Molecular Microbiology. 63, 5, p. 1285-1295 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      SpxB regulates O-acetylation-dependent resistance of Lactococcus lactis peptidoglycan to hydrolysis

      Veiga, P., Bulbarela-Sampieri, C., Furlan, S., Maisons, A., Chapot-Chartier, M., Erkelenz, M., Mervelet, P., Noirot, P., Frees, Dorte, Kuipers, O. P., Kok, J., Gruss, A., Buist, G. & Kulakauskas, S., 2007, In: Journal of Biological Chemistry. 282, 27, p. 19342-19354 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      The role of ClpX in Staphylococcus aureus stress response and virulence

      Rasmussen, T., Frees, Dorte & Thomsen, Line Elnif, 2007. 1 p.

      Research output: Contribution to conferencePosterResearch

    30. 2006
    31. Published

      Identification of the ClpX Regulon in Staphylococcus aureus

      Jelsbak, L., Thomsen, Line Elnif, Ingmer, Hanne, Donat, S., Ohlsen, K. & Frees, Dorte, 2006. 1 p.

      Research output: Contribution to conferencePosterResearch

    32. Published

      Spx is a global effector impacting stress tolerance and biofilm formation in Staphylococcus aureus

      Pamp, S. J., Frees, Dorte, Engelmann, S., Hecker, M. & Ingmer, Hanne, 2006, In: Journal of Bacteriology. 188, 13, p. 4861-4870 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. 2005
    34. Published

      Salmonella isolates with different behavior in adhesion to surfaces studied by DNA micro array assisted analysis

      Holmstrøm, K., Olsen, K. N., Meldgaard, H., Bagge-Ravn, D., Frees, Dorte, Lauritsen, D., Gram, L. & Olsen, John Elmerdahl, 2005. 1 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearch

    35. Published

      Global virulence regulation in Staphylococcus aureus: pinpointing the roles of ClpP and ClpX in the sar/agr regulatory network

      Frees, Dorte, Sørensen, K. & Ingmer, Hanne, 2005, In: Infection and Immunity. 73, 12, p. 8100-8108 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Staphylococcus aureus ClpYQ plays a minor role in stress survival

      Frees, Dorte, Thomsen, Line Elnif & Ingmer, Hanne, 2005, In: Archives of Microbiology. 183, 4, p. 286-291 6 p.

      Research output: Contribution to journalJournal articleResearch

    37. 2004
    38. Published

      Clp ATPases are required for stress tolerance, intracellular replication and biofilm formation in Staphylococcus aureus

      Frees, Dorte, Chastanet, A., Quzi, S., Sørensen, K., Hill, P., Msadek, T. & Ingmer, Hanne, 2004, In: Molecular Microbiology. 54, 5, p. 1445-1462 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. 2003
    40. Published

      Alternative roles of CIpX and CIpP in Staphylococus aureus stress toelrance and virulence.

      Frees, Dorte, Saara, N. A. Q., Philip, J. H. & Ingmer, Hanne, 2003, In: Molecular Microbiology. (2003) 48 (6), p. 1565 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Heat and DNA damage induction of the LexA-like regulator HdiR from Lactococcus lactis is mediated by RecA and ClpP

      Savijoki, K., Ingmer, Hanne, Frees, Dorte, Vogensen, Finn Kvist, Palva, A. & Varmanen, P., 2003, In: Molecular Microbiology. 50, 2, p. s.609-621 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Identification of proteins induced at low pH in Lactococcus lactis

      Frees, Dorte, Vogensen, Finn Kvist & Ingmer, Hanne, 2003, In: International Journal of Food Microbiology. 87, 87, p. 293-300 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Stress toelrance mechanisms influencing virulence and survival of food borne pathogens

      Frees, Dorte, Varmanen, P. ;., SavijokiK.;, Andersen, M. T., Brønsted, L. & Ingmer, Hanne, 2003. 1 p.

      Research output: Contribution to conferencePaperResearch

    44. 2001
    45. Published

      Inactivation of a gene that is highly conserved in Gram-positive bacteria stimulates degradation of non-native proteins and concomitantly increases stress tolerance in Lactococcus lactis

      Frees, Dorte, Varmanen, P. & Ingmer, Hanne, 2001, In: Molecular Microbiology. 41, 1, p. 93-103 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. 1999
    47. Published

      ClpP participaytes in the degradation of misfolded protein in Lactococcuss lactis

      Frees, Dorte & Ingmer, Hanne, 1999, In: Molecular Microbiology. 31, 1, p. 79 - 87 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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