Genome-wide Linkage Disequilibrium Linkage Analysis (LDLA) of Body Fat Traits in an F2 Porcine Model for Human Obesity

Publikation: Konferencebidrag › Poster › Forskning › fagfællebedømt

Standard

Genome-wide Linkage Disequilibrium Linkage Analysis (LDLA) of Body Fat Traits in an F2 Porcine Model for Human Obesity. / Pant, Sameer Dinkar; Karlskov-Mortensen, Peter; Cirera Salicio, Susanna; Kogelman, Lisette; Jacobsen, Mette Juul; Bruun, Camilla Vibeke Sichlau; Jørgensen, Claus Bøttcher; Meuwissen, T.H.E.; Kadarmideen, Haja; Fredholm, Merete.

2014. Poster session præsenteret ved 10th World Congress of Genetics Applied to Livestock Production, Vancouver, Canada.

Publikation: Konferencebidrag › Poster › Forskning › fagfællebedømt

Harvard

Pant, SD, Karlskov-Mortensen, P, Cirera Salicio, S, Kogelman, L, Jacobsen, MJ, Bruun, CVS, Jørgensen, CB, Meuwissen, THE, Kadarmideen, H & Fredholm, M 2014, 'Genome-wide Linkage Disequilibrium Linkage Analysis (LDLA) of Body Fat Traits in an F2 Porcine Model for Human Obesity', 10th World Congress of Genetics Applied to Livestock Production, Vancouver, Canada, 16/08/2014 - 23/08/2014. <https://asas.org/docs/default-source/wcgalp-posters/595_paper_8938_manuscript_319_0.pdf?sfvrsn=2>

APA

Pant, S. D., Karlskov-Mortensen, P., Cirera Salicio, S., Kogelman, L., Jacobsen, M. J., Bruun, C. V. S., Jørgensen, C. B., Meuwissen, T. H. E., Kadarmideen, H., & Fredholm, M. (2014). Genome-wide Linkage Disequilibrium Linkage Analysis (LDLA) of Body Fat Traits in an F2 Porcine Model for Human Obesity. Poster session præsenteret ved 10th World Congress of Genetics Applied to Livestock Production, Vancouver, Canada. https://asas.org/docs/default-source/wcgalp-posters/595_paper_8938_manuscript_319_0.pdf?sfvrsn=2

Vancouver

Pant SD, Karlskov-Mortensen P, Cirera Salicio S, Kogelman L, Jacobsen MJ, Bruun CVS o.a.. Genome-wide Linkage Disequilibrium Linkage Analysis (LDLA) of Body Fat Traits in an F2 Porcine Model for Human Obesity. 2014. Poster session præsenteret ved 10th World Congress of Genetics Applied to Livestock Production, Vancouver, Canada.

Author

Pant, Sameer Dinkar ; Karlskov-Mortensen, Peter ; Cirera Salicio, Susanna ; Kogelman, Lisette ; Jacobsen, Mette Juul ; Bruun, Camilla Vibeke Sichlau ; Jørgensen, Claus Bøttcher ; Meuwissen, T.H.E. ; Kadarmideen, Haja ; Fredholm, Merete. / Genome-wide Linkage Disequilibrium Linkage Analysis (LDLA) of Body Fat Traits in an F2 Porcine Model for Human Obesity. Poster session præsenteret ved 10th World Congress of Genetics Applied to Livestock Production, Vancouver, Canada.4 s.

Bibtex

@conference{9a655cd639d0495f86c0239b3cbf61d2,
title = "Genome-wide Linkage Disequilibrium Linkage Analysis (LDLA) of Body Fat Traits in an F2 Porcine Model for Human Obesity",
abstract = "ABSTRACT: Purebred Duroc and Yorkshire sows werecrossed with G{\"o}ttingen minipig boars to obtain two separateF2 intercross resource populations (n=287 and 279respectively). Several obesity, metabolic and slaughtermeasurements were recorded from birth to slaughter (220 ±45 days). In addition, body composition was determined atabout two months of age (64 ± 11 days) via dual-energy xrayabsorptiometry (DXA) scanning. All pigs weregenotyped using Illumina Porcine 60k SNP Beadchip and acombined LDLA approach was used to perform genomewidelinkage and association analysis for body fat traits.Subsequently bioinformatic analysis was performed toidentify genes in close proximity of chromosomal positionswhere statistically significant QTLs were identified. Severalimportant genes previously linked to obesity (e.g. BBS4,CHRNA2, DLK1), along with other novel genes wereidentified, that together provide novel insights that mayfurther the current understanding of the molecularmechanisms underlying human obesity.",
author = "Pant, {Sameer Dinkar} and Peter Karlskov-Mortensen and {Cirera Salicio}, Susanna and Lisette Kogelman and Jacobsen, {Mette Juul} and Bruun, {Camilla Vibeke Sichlau} and J{\o}rgensen, {Claus B{\o}ttcher} and T.H.E. Meuwissen and Haja Kadarmideen and Merete Fredholm",
year = "2014",
language = "English",
note = "null ; Conference date: 16-08-2014 Through 23-08-2014",

}

RIS

TY - CONF

T1 - Genome-wide Linkage Disequilibrium Linkage Analysis (LDLA) of Body Fat Traits in an F2 Porcine Model for Human Obesity

AU - Pant, Sameer Dinkar

AU - Karlskov-Mortensen, Peter

AU - Cirera Salicio, Susanna

AU - Kogelman, Lisette

AU - Jacobsen, Mette Juul

AU - Bruun, Camilla Vibeke Sichlau

AU - Jørgensen, Claus Bøttcher

AU - Meuwissen, T.H.E.

AU - Kadarmideen, Haja

AU - Fredholm, Merete

PY - 2014

Y1 - 2014

N2 - ABSTRACT: Purebred Duroc and Yorkshire sows werecrossed with Göttingen minipig boars to obtain two separateF2 intercross resource populations (n=287 and 279respectively). Several obesity, metabolic and slaughtermeasurements were recorded from birth to slaughter (220 ±45 days). In addition, body composition was determined atabout two months of age (64 ± 11 days) via dual-energy xrayabsorptiometry (DXA) scanning. All pigs weregenotyped using Illumina Porcine 60k SNP Beadchip and acombined LDLA approach was used to perform genomewidelinkage and association analysis for body fat traits.Subsequently bioinformatic analysis was performed toidentify genes in close proximity of chromosomal positionswhere statistically significant QTLs were identified. Severalimportant genes previously linked to obesity (e.g. BBS4,CHRNA2, DLK1), along with other novel genes wereidentified, that together provide novel insights that mayfurther the current understanding of the molecularmechanisms underlying human obesity.

AB - ABSTRACT: Purebred Duroc and Yorkshire sows werecrossed with Göttingen minipig boars to obtain two separateF2 intercross resource populations (n=287 and 279respectively). Several obesity, metabolic and slaughtermeasurements were recorded from birth to slaughter (220 ±45 days). In addition, body composition was determined atabout two months of age (64 ± 11 days) via dual-energy xrayabsorptiometry (DXA) scanning. All pigs weregenotyped using Illumina Porcine 60k SNP Beadchip and acombined LDLA approach was used to perform genomewidelinkage and association analysis for body fat traits.Subsequently bioinformatic analysis was performed toidentify genes in close proximity of chromosomal positionswhere statistically significant QTLs were identified. Severalimportant genes previously linked to obesity (e.g. BBS4,CHRNA2, DLK1), along with other novel genes wereidentified, that together provide novel insights that mayfurther the current understanding of the molecularmechanisms underlying human obesity.

M3 - Poster

Y2 - 16 August 2014 through 23 August 2014

ER -

ID: 140392873